-
1
-
-
84877100240
-
Analysis of tumor specimens at the time of acquired resistance to EGFR-TKI therapy in 155 patients with EGFR-mutant lung cancers
-
Yu Ha, Arcila ME, Rekhtman N, et al. Analysis of tumor specimens at the time of acquired resistance to EGFR-TKI therapy in 155 patients with EGFR-mutant lung cancers. Clin Cancer Res 2013; 19: 2240-2247
-
(2013)
Clin Cancer Res
, vol.19
, pp. 2240-2247
-
-
Yu, H.A.1
Arcila, M.E.2
Rekhtman, N.3
-
2
-
-
84942106463
-
Epidermal growth factor receptor-mutant lung cancer: New drugs, new resistance mechanisms, and future treatment options
-
Piotrowska Z, Sequist L. Epidermal growth factor receptor-mutant lung cancer: New drugs, new resistance mechanisms, and future treatment options. Cancer J 2015; 21,371-377
-
(2015)
Cancer J
, vol.21
, pp. 371-377
-
-
Piotrowska, Z.1
Sequist, L.2
-
3
-
-
84904898065
-
AZD9291 an irreversible EGFR TKI overcomes T790M-mediated resistance to EGFR inhibitors in lung cancer
-
Cross DA, Ashton SE, Ghiorghiu S, et al. AZD9291, an irreversible EGFR TKI, overcomes T790M-mediated resistance to EGFR inhibitors in lung cancer. Cancer Discov 2014; 4: 1046-1061
-
(2014)
Cancer Discov
, vol.4
, pp. 1046-1061
-
-
Cross, D.A.1
Ashton, S.E.2
Ghiorghiu, S.3
-
4
-
-
84908371107
-
Discovery of a potent and selective EGFR inhibitor (AZD9291) of both sensitizing and T790M resistance mutations that spares the wild type form of the receptor
-
Finlay MR, Anderton M, Ashton S, et al. Discovery of a potent and selective EGFR inhibitor (AZD9291) of both sensitizing and T790M resistance mutations that spares the wild type form of the receptor. J Med Chem 2014; 57: 8249-8267
-
(2014)
J Med Chem
, vol.57
, pp. 8249-8267
-
-
Finlay, M.R.1
Anderton, M.2
Ashton, S.3
-
5
-
-
84928739294
-
AZD9291 in EGFR inhibitor-resistant non-small-cell lung cancer
-
Jänne PA, Yang JC, Kim DW, et al. AZD9291 in EGFR inhibitor-resistant non-small-cell lung cancer. N Engl J Med 2015; 372: 1689-1699
-
(2015)
N Engl J Med
, vol.372
, pp. 1689-1699
-
-
Jänne, P.A.1
Yang, J.C.2
Kim, D.W.3
-
6
-
-
84928746232
-
Rociletinib in EGFR-mutated non-small-cell lung cancer
-
Sequist LV, Soria JC, Goldman JW, et al. Rociletinib in EGFR-mutated non-small-cell lung cancer. N Engl J Med 2015; 372: 1700-1709
-
(2015)
N Engl J Med
, vol.372
, pp. 1700-1709
-
-
Sequist, L.V.1
Soria, J.C.2
Goldman, J.W.3
-
7
-
-
84865197331
-
Efficacy of epidermal growth factor receptor tyrosine kinase inhibitors for brain metastasis in non-small cell lung cancer patients harboring either exon 19 or 21 mutation
-
Park SJ, Kim HT, Lee DH, et al. Efficacy of epidermal growth factor receptor tyrosine kinase inhibitors for brain metastasis in non-small cell lung cancer patients harboring either exon 19 or 21 mutation. Lung Cancer 2012; 77: 556-560
-
(2012)
Lung Cancer
, vol.77
, pp. 556-560
-
-
Park, S.J.1
Kim, H.T.2
Lee, D.H.3
-
8
-
-
84980342628
-
Preclinical activity of AZD9291 in-EGFR-mutant NSCLC brain metastases
-
abstract Mini 10.12
-
Ballard P, et al Preclinical activity of AZD9291 in-EGFR-mutant NSCLC brain metastases J Thorac Oncol 2015 10(9, Suppl2): S300, abstract Mini 10.12
-
(2015)
J Thorac Oncol
, vol.10
, Issue.9
, pp. S300
-
-
Ballard, P.1
-
9
-
-
84945255542
-
Spatiotemporal T790M heterogeneity in individual patients with EGFR-mutant non-small-cell lung cancer after acquired resistance to EGFR-TKI
-
Hata A, Katakami N, Yoshioka H, et al. Spatiotemporal T790M heterogeneity in individual patients with EGFR-mutant non-small-cell lung cancer after acquired resistance to EGFR-TKI. J Thorac Oncol 2015; 10: 1553-1559
-
(2015)
J Thorac Oncol
, vol.10
, pp. 1553-1559
-
-
Hata, A.1
Katakami, N.2
Yoshioka, H.3
-
10
-
-
84901602817
-
Incidence of T790M mutation in (sequential) rebiopsies in EGFR-mutated NSCLC-patients
-
Kuiper JL, Heideman DA, Thunnissen E, et al. Incidence of T790M mutation in (sequential) rebiopsies in EGFR-mutated NSCLC-patients. Lung Cancer 2014; 85: 19-24
-
(2014)
Lung Cancer
, vol.85
, pp. 19-24
-
-
Kuiper, J.L.1
Heideman, D.A.2
Thunnissen, E.3
-
11
-
-
84922949424
-
Prognostic impact of central nervous system metastases after acquired resistance to EGFR-TKI: Poorer prognosis associated with T790M-negative status and leptomeningeal metastases
-
Hata A, Katakami N, Yoshioka H, et al. Prognostic impact of central nervous system metastases after acquired resistance to EGFR-TKI: Poorer prognosis associated with T790M-negative status and leptomeningeal metastases. Anticancer Res 2015; 35: 1025-1031
-
(2015)
Anticancer Res
, vol.35
, pp. 1025-1031
-
-
Hata, A.1
Katakami, N.2
Yoshioka, H.3
-
12
-
-
84875950992
-
Epidermal growth factor receptor tyrosine kinase inhibitor-resistant disease
-
Ohashi K, Maruvka YE, Michor F, Pao E. Epidermal growth factor receptor tyrosine kinase inhibitor-resistant disease. J Clin Oncol 2013; 31: 1070-1080
-
(2013)
J Clin Oncol
, vol.31
, pp. 1070-1080
-
-
Ohashi, K.1
Maruvka, Y.E.2
Michor, F.3
Pao, E.4
|