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Volumn 22, Issue 12, 2016, Pages 2832-2834

MET exon 14 alterations in lung cancer: Exon skipping extends half-life

Author keywords

[No Author keywords available]

Indexed keywords

CABOZANTINIB; CAPMATINIB; CRIZOTINIB; ONARTUZUMAB; PROTEOME; SCATTER FACTOR RECEPTOR;

EID: 84975076400     PISSN: 10780432     EISSN: 15573265     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-16-0229     Document Type: Article
Times cited : (42)

References (12)
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  • 3
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    • Point mutations in the dystrophin gene: Evidence for frequent use of cryptic splice sites as a result of splicing defects
    • Tuffery-Giraud S, Chambert S, Demaille J, Claustres M. Point mutations in the dystrophin gene: evidence for frequent use of cryptic splice sites as a result of splicing defects. Hum Mutat 1999;14:359-68.
    • (1999) Hum Mutat , vol.14 , pp. 359-368
    • Tuffery-Giraud, S.1    Chambert, S.2    Demaille, J.3    Claustres, M.4
  • 4
    • 33746927884 scopus 로고    scopus 로고
    • The connection between splicing and cancer
    • Srebrow A, Kornblihtt AR. The connection between splicing and cancer. J Cell Sci 2006;119:2635-41.
    • (2006) J Cell Sci , vol.119 , pp. 2635-2641
    • Srebrow, A.1    Kornblihtt, A.R.2
  • 5
    • 84938805958 scopus 로고    scopus 로고
    • Activation of MET via diverse exon 14 splicing alterations occurs in multiple tumor types and confers clinical sensitivity to MET inhibitors
    • Frampton GM, Ali SM, Rosenzweig M, Chmielecki J, Lu X, Bauer TM, et al. Activation of MET via diverse exon 14 splicing alterations occurs in multiple tumor types and confers clinical sensitivity to MET inhibitors. Cancer Discov 2015;5:850-9.
    • (2015) Cancer Discov , vol.5 , pp. 850-859
    • Frampton, G.M.1    Ali, S.M.2    Rosenzweig, M.3    Chmielecki, J.4    Lu, X.5    Bauer, T.M.6
  • 7
    • 0035930341 scopus 로고    scopus 로고
    • Mutation of the c-Cbl TKB domain binding site on the Met receptor tyrosine kinase converts it into a transforming protein
    • Peschard P, Fournier TM, Lamorte L, Naujokas MA, Band H, Langdon WY, et al. Mutation of the c-Cbl TKB domain binding site on the Met receptor tyrosine kinase converts it into a transforming protein. Mol Cell 2001;8:995-1004.
    • (2001) Mol Cell , vol.8 , pp. 995-1004
    • Peschard, P.1    Fournier, T.M.2    Lamorte, L.3    Naujokas, M.A.4    Band, H.5    Langdon, W.Y.6
  • 8
    • 84962609567 scopus 로고    scopus 로고
    • Next-generation sequencing of pulmonary sarcomatoid carcinoma reveals high frequency of actionable MET gene mutations
    • Liu X, Jia Y, Stoopler MB, Shen Y, Cheng H, Chen J, et al. Next-generation sequencing of pulmonary sarcomatoid carcinoma reveals high frequency of actionable MET gene mutations. J Clin Oncol 2016;34:794-802.
    • (2016) J Clin Oncol , vol.34 , pp. 794-802
    • Liu, X.1    Jia, Y.2    Stoopler, M.B.3    Shen, Y.4    Cheng, H.5    Chen, J.6
  • 9
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    • MET exon 14 mutations in non-small-cell lung cancer are associated with advanced age and stage-dependent MET genomic amplification and c-Met overexpression
    • Awad MM, Oxnard GR, Jackman DM, Savukoski DO, Hall D, Shivdasani P, et al. MET exon 14 mutations in non-small-cell lung cancer are associated with advanced age and stage-dependent MET genomic amplification and c-Met overexpression. J Clin Oncol 2016;34:721-30.
    • (2016) J Clin Oncol , vol.34 , pp. 721-730
    • Awad, M.M.1    Oxnard, G.R.2    Jackman, D.M.3    Savukoski, D.O.4    Hall, D.5    Shivdasani, P.6
  • 10
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    • Gastrointestinal malignancies harbor actionable MET exon 14 deletions
    • Lee J, Ou SH, Lee JM, Kim HC, Hong M, Kim SY, et al. Gastrointestinal malignancies harbor actionable MET exon 14 deletions. Oncotarget 2015;6:28211-22.
    • (2015) Oncotarget , vol.6 , pp. 28211-28222
    • Lee, J.1    Ou, S.H.2    Lee, J.M.3    Kim, H.C.4    Hong, M.5    Kim, S.Y.6
  • 11
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    • Functional expression and mutations of c-Met and its therapeutic inhibition with SU11274 and small interfering RNA in non-small cell lung cancer
    • Ma PC, Jagadeeswaran R, Jagadeesh S, Tretiakova MS, Nallasura V, Fox EA, et al. Functional expression and mutations of c-Met and its therapeutic inhibition with SU11274 and small interfering RNA in non-small cell lung cancer. Cancer Res 2005;65:1479-88.
    • (2005) Cancer Res , vol.65 , pp. 1479-1488
    • Ma, P.C.1    Jagadeeswaran, R.2    Jagadeesh, S.3    Tretiakova, M.S.4    Nallasura, V.5    Fox, E.A.6
  • 12
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    • Response to MET inhibitors in patients with stage IV lung adenocarcinomas harboring MET mutations causing exon 14 skipping
    • Paik PK, Drilon A, Fan PD, Yu H, Rekhtman N, Ginsberg MS, et al. Response to MET inhibitors in patients with stage IV lung adenocarcinomas harboring MET mutations causing exon 14 skipping. Cancer Discov 2015;5:842-9.
    • (2015) Cancer Discov , vol.5 , pp. 842-849
    • Paik, P.K.1    Drilon, A.2    Fan, P.D.3    Yu, H.4    Rekhtman, N.5    Ginsberg, M.S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.