Cationic drug-based self-assembled polyelectrolyte complex micelles: Physicochemical, pharmacokinetic, and anticancer activity analysis

Colloids and Surfaces B: Biointerfaces

Volumn 146, Issue , 2016, Pages 152-160

  Ramasamy, Thiruganesh ^a   Poudel, Bijay Kumar ^a   Ruttala, Himabindu ^a   Choi, Ju Yeon ^a   Hieu, Truong Duy ^a   Umadevi, Kandasamy ^b   Youn, Yu Seok ^c   Choi, Han Gon ^d   Yong, Chul Soon ^a   Kim, Jong Oh ^a  

^a Yeungnam University   (South Korea)

^b OSMANIA UNIVERSITY   (India)

^c Sungkyunkwan University   (South Korea)

^d Hanyang University   (South Korea)

Author keywords

Anticancer activity; Cationic drugs; Nanofabrication; Pharmacokinetic; Polyelectrolyte complex micelles

Indexed keywords

BLOCK COPOLYMERS; BLOOD; CELL DEATH; CONTROLLED DRUG DELIVERY; DISEASES; DRUG INTERACTIONS; ETHYLENE; MICELLES; NANOTECHNOLOGY; PHARMACOKINETICS; POLYELECTROLYTES; POLYETHYLENE OXIDES; SELF ASSEMBLY;

ANTICANCER ACTIVITIES; BIOLOGICAL PERFORMANCE; CATIONIC DRUGS; IONIC BLOCK COPOLYMERS; PHARMACOKINETIC STUDIES; PHYSICOCHEMICAL PROPERTY; POLY(ACRYLIC ACID ); POLYELECTROLYTE COMPLEXES;

TARGETED DRUG DELIVERY;

ACRYLIC ACID; DOXORUBICIN; MITOXANTRONE; POLY(ETHYLENE OXIDE) BLOCK POLY(ACRYLIC ACID); UNCLASSIFIED DRUG; ANTINEOPLASTIC ANTIBIOTIC; CATION; DRUG CARRIER; MICELLE; POLYELECTROLYTE; POLYMER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; AREA UNDER THE CURVE; ARTICLE; CANCER CELL; CANCER INHIBITION; CIRCULATION; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DELIVERY SYSTEM; DRUG HALF LIFE; DRUG RELEASE; DRUG STABILITY; FEMALE; IN VITRO STUDY; IN VIVO STUDY; LUNG CANCER; MALE; MAXIMUM PLASMA CONCENTRATION; MEAN RETENTION TIME; MICELLE; MOUSE; NONHUMAN; PARTICLE SIZE; PH; PHARMACOLOGICAL PARAMETERS; PHYSICAL CHEMISTRY; POLYELECTROLYTE COMPLEX MICELLE; PRIORITY JOURNAL; RAT; SINGLE DRUG DOSE; TIME TO MAXIMUM PLASMA CONCENTRATION; TUMOR VOLUME; TUMOR XENOGRAFT; ZETA POTENTIAL; ANIMAL; BAGG ALBINO MOUSE; CELL PROLIFERATION; CHEMISTRY; DRUG EFFECTS; DRUG SCREENING; HUMAN; LUNG NEOPLASMS; NUDE MOUSE; PATHOLOGY; TISSUE DISTRIBUTION; TUMOR CELL CULTURE;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; APOPTOSIS; CATIONS; CELL PROLIFERATION; DOXORUBICIN; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; FEMALE; HUMANS; LUNG NEOPLASMS; MICE; MICE, INBRED BALB C; MICE, NUDE; MICELLES; POLYELECTROLYTES; POLYMERS; TISSUE DISTRIBUTION; TUMOR CELLS, CULTURED; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84974695966     PISSN: 09277765     EISSN: 18734367     Source Type: Journal    
DOI: 10.1016/j.colsurfb.2016.06.004     Document Type: Article

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