Telocytes contribute as cell progenitors and differentiation inductors in tissue regeneration

Current Stem Cell Research and Therapy

Volumn 11, Issue 5, 2016, Pages 383-389

  Vannucchi, Maria Giuliana ^a   Bani, Daniele ^a   Faussone Pellegrini, Maria Simonetta ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

Author keywords

Fibroblasts; Immunohistochemistry; Interstitial cells of Cajal; Mesenchymal stromal cells; Myofibroblasts; Ultrastructure

Indexed keywords

ARTICLE; CELL DIFFERENTIATION; CELL MATURATION; CELL PROLIFERATION; CELL SURVIVAL; CELL ULTRASTRUCTURE; FIBROBLAST; HUMAN; IMMUNOHISTOCHEMISTRY; INTERSTITIAL CELL OF CAJAL; MORPHOGENESIS; MYOFIBROBLAST; NONHUMAN; PRIORITY JOURNAL; STEM CELL; TELOCYTE; TISSUE DIFFERENTIATION; TISSUE REGENERATION; ANIMAL; CYTOLOGY; ORGANOGENESIS; REGENERATION; ULTRASTRUCTURE;

ANIMALS; CELL DIFFERENTIATION; HUMANS; ORGANOGENESIS; REGENERATION; STEM CELLS; TELOCYTES;

EID: 84974667159     PISSN: 1574888X     EISSN: None     Source Type: Journal    
DOI: 10.2174/1574888X10666150528142741     Document Type: Article

References (62)

1. Popescu LM, Faussone-Pellegrini MS. TELOCYTES-a case of serendipity: the winding way from Interstitial Cells of Cajal (ICC), via Interstitial Cajal-Like Cells (ICLC) to TELOCYTES. J Cell Mol Med 2010; 14: 729-40.
2. Pieri L, Vannucchi MG, Faussone-Pellegrini MS. Histochemical and ultrastructural characteristics of an interstitial cell type different from ICC and resident in the muscle coat of human gut. J Cell Mol Med 2008; 12: 1944-55.
3. Kostin S, Popescu LM. A distinct type of cell in myocardium: interstitial Cajal-like cells [ICLCs]. J Cell Mol Med 2009; 13: 295-308.
4. Faussone-Pellegrini MS, Popescu LM. Telocytes. Biomol Concepts 2011; 2: 481-9.
5. Cretoiu SM, Popescu LM. Telocytes revisited. Biomol Conc 2014; 5(5): 353-69.
6. Vannucchi MG, Traini C, Guasti D, del Popolo G, Faussone-Pellegrini MS. Telocytes subtypes in human urinary bladder. J Cell Mol Med 2014; 18: 2000-8.
7. Gevaert T, De Vos R, Van Der Aa F, et al. Identification of telocytes in the upper lamina propria of the human urinary tract. J Cell Mol Med 2012; 16: 2085-93.
8. Vannucchi MG, Traini C, Manetti M, Ibba-Manneschi L, Faussone-Pellegrini MS. Telocytes express PDGFRalpha in the human gastrointestinal tract. J Cell Mol Med 2013; 17: 1099-108.
9. Kurahashi M, Nakano Y, Peri LE, Townsend JB, Ward SM, Sanders KM. A novel population of subepithelial platelet-derived growth factor receptor α-positive cells in the mouse and human colon. Am J Physiol Gastrointest Liver Physiol 2013; 304: G823-34.
10. Hinescu ME, Popescu LM, Gherghiceanu M, Faussone-Pellegrini MS. Interstitial Cajal-like cells in rat mesentery: an ultrastructural and immunohistochemical approach. J Cell Mol Med 2008; 12: 260-70.
11. Cretoiu SM, Cretoiu D, Popescu LM. Human myometrium-the ultrastructural 3D network of telocytes. J Cell Mol Med 2012; 16: 2844-9.
12. Grover M, Bernard CE, Pasricha PJ, et al. Platelet-derived growth factor receptor α (PDGFRα)-expressing "fibroblast-like cells" in diabetic and idiopathic gastroparesis of humans. Neurogastroenterol Motil 2012; 24: 844-52.
13. Wiseman OJ, Brady CM, Hussain IF, et al. The ultrastructure of bladder lamina propria nerves in healthy subjects and patients with detrusor hyperreflexia. J Urol 2002; 168: 2040-45.
14. Diaz-Flores L, Gutierrez R, Saez FJ, Diaz-Flores L, Jr., Madrid JF. Telocytes in neuromuscular spindles. J Cell Mol Med 2013; 17: 457-65.
15. Koh BH, Roy R, Hollywood MA, et al. Platelet-derived growth factor receptor-alpha cells in mouse urinary bladder: a new class of interstitial cells. J Cell Mol Med 2012; 16: 691-700.
16. Sanders KM, Ward SM, Koh SD. Interstitial cells: regulators of smooth muscle function. Physiol Rev 2014; 94: 859-907.
17. Gibbons SJ, De Giorgio R, Faussone Pellegrini MS, et al. Apoptotic cell death of human interstitial cells of Cajal. Neurogastroenterol Motil 2009; 2: 85-93.
18. Lorincz A, Redelman D, Horváth VJ, Bardsley MR, Chen H, Ordög T. Progenitors of interstitial cells of Cajal in the postnatal murine stomach. Gastroenterology 2008; 134: 1083-93.
19. Huizinga JD, White EJ. Progenitor cells of interstitial cells of Cajal: on the road to tissue repair. Gastroenterology 2008; 134: 1252-3.
20. Faussone Pellegrini MS. Morphogenesis of the special circular muscle layer and of the interstitial cells of Cajal related to the plexus muscularis profundus of mouse intestinal muscle coat. An E.M. study. Anat Embryol (Berl) 1984; 169: 151-8.
21. Faussone-Pellegrini MS. Cytodifferentiation of the interstitial cells of Cajal of mouse colonic circular muscle layer. An EM study from fetal to adult life. Acta Anat (Basel) 1987; 128: 98-109.
22. Faussone-Pellegrini MS, Vannucchi MG, Alaggio R, Strojna A, Midrio P. Morphology of the interstitial cells of Cajal of the human ileum from foetal to neonatal life. J Cell Mol Med 2007; 11: 482-94.
23. Faussone-Pellegrini MS, Vannucchi MG, Ledder O, Huang TY, Hanani M. Plasticity of interstitial cells of Cajal: a study of mouse colon. Cell Tissue Res 2006; 325: 211-7.
24. McCann CJ, Hwang SJ, Hennig GW, Ward SM, Sanders KM. Bone Marrow Derived Kit-positive Cells Colonize the Gut but Fail to Restore Pacemaker Function in Intestines Lacking Interstitial Cells of Cajal. J Neurogastroenterol Motil 2014; 20: 326-37.
25. Eyden B. The Myofibroblast: A Study of Normal, Reactive and Neoplastic Tissues with an Emphasis on Ultrastructure. Nuova Immagine Editrice: Siena, Italy, 2007.
26. Odelberg SJ. Cellular plasticity in vertebrate regeneration. Anat Rec B New Anat 2005; 287: 25-35.
27. Yannas IV. Similarities and differences between induced organ regeneration in adults and early foetal regeneration. J R Soc Interface 2005; 2: 403-17.
28. Crawford JR, Haudek SB, Cieslik KA, et al. Origin of developmental precursors dictates the pathophysiologic role of cardiac fibroblasts. J Cardiovasc Transl Res. 2012; 5: 749-59.
29. Suciu L, Popescu LM, Gherghiceanu M, et al. Telocytes in human term placenta: morphology and phenotype. Cells Tissues Organs 2010; 192: 325-39.
30. Diaz-Flores L, Gutierrez R, Garcia MP, et al. CD34+ stromal cells/fibroblasts/fibrocytes/telocytes as a tissue reserve and a principal source of mesenchymal cells. Location, morphology, function and role in pathology. Histol Histopathol 2014; 29: 831-70.
31. Manetti M, Guiducci S, Ruffo M, et al. Evidence for progressive reduction and loss of telocytes in the dermal cellular network of systemic sclerosis. J Cell Mol Med 2013; 17: 482-96.
32. Milia AF, Ruffo M, Manetti M, et al. Telocytes in Crohn's disease. J Cell Mol Med 2013; 17: 1525-36.
33. Manetti M, Rosa I, Messerini L, Guiducci S, Matucci-Cerinic M, Ibba-Manneschi L. A loss of telocytes accompanies fibrosis of multiple organs in systemic sclerosis. J Cell Mol Med 2014; 18: 253-62.
34. Manetti M, Rosa I, Messerini L, Ibba-Manneschi L. A loss of telocytes accompanies inflammation-driven fibrotic remodelling of the colonic wall in ulcerative colitis. J Cell Mol Med 2014 Oct 6. doi: 10.1111/jcmm.12457.
35. Cretoiu D, Ciontea SM, Popescu LM, Ceafalan L, Ardeleanu C. Interstitial Cajal-like cells (ICLC) as steroid hormone sensors in human myometrium: immunocytochemical approach. J Cell Mol Med 2006; 10: 789-95.
36. Cretoiu SM, Cretoiu D, Suciu L, Popescu LM. Interstitial Cajallike cells of human Fallopian tube express estrogen and progesterone receptors. J Mol Histol 2009; 40: 387-94.
37. Gherghiceanu M, Popescu LM. Cardiomyocyte precursors and telocytes in epicardial stem cell niche: electron microscope images. J Cell Mol Med 2010; 14: 871-7.
38. Popescu LM, Manole CG, Gherghiceanu M, et al. Telocytes in human epicardium. J Cell Mol Med 2010; 14: 2085-93.
39. Popescu LM. The tandem: telocytes-stem cells. Int J Biol Biomed Eng 2011; 5:83-92.
40. Bojin FM, Gavriliuc OI, Cristea MI, et al. Telocytes within human skeletal muscle stem cell niche. J Cell Mol Med 2011; 15: 2269-72.
41. Popescu LM, Manole E, Serboiu CS, et al. Identification of telocytes in skeletal muscle interstitium: implication for muscle regeneration. J Cell Mol Med 2011; 15: 1379-92.
42. Luesma MJ, Gherghiceanu M, Popescu LM. Telocytes and stem cells in limbus and uvea of mouse eye. J Cell Mol Med 2013; 17: 1016-24.
43. Ceafalan LC, Popescu BO, Hinescu ME. Cellular players in skeletal muscle regeneration. Biomed Res Int 2014; 2014: 957014. doi: 10.1155/2014/957014. Epub 2014 Mar 23.
44. Wang F, Song Y, Bei Y, Zhao Y, Xiao J, Yang C. Telocytes in liver regeneration: possible roles. J Cell Mol Med 2014; 18: 1720-6.
45. Hsu YC, Li L, Fuchs E. Emerging interactions between skin stem cells and their niches. Nat Med 2014; 20: 847-56.
46. Hoch RV, Soriano P. Roles of PDGF in animal development. Development 2003; 130: 4769-84.
47. Andrae J, Gallini R, Betsholtz C. Role of platelet-derived growth factors in physiology and medicine. Genes Dev 2008; 22: 276-312.
48. Karlsson L, Lindahl P, Heath JK, Betsholtz C. Abnormal gastrointestinal development in PDGF-A and PDGFR-(alpha) deficient mice implicates a novel mesenchymal structure with putative instructive properties in villus morphogenesis. Development 2000; 127: 457-66.
49. Kurahashi M, Niwa Y, Cheng J, et al. Platelet-derived growth factor signals play critical roles in differentiation of longitudinal smooth muscle cells in mouse embryonic gut. Neurogastroenterol Motil 2008; 20: 521-31.
50. Smythies J, Edelstein L. Telocytes, exosomes, gap junctions and the cytoskeleton: the makings of a primitive nervous system? Front Cell Neurosci 2014; 7: 1-3.
51. Bani D, Nistri S. New insights into the morphogenic role of stromal cells and their relevance for regenerative medicine. Lessons from the heart. J Cell Mol Med 2014; 18: 363-70.
52. Bani D, Formigli L, Gherghiceanu M, Faussone-Pellegrini MS. Telocytes as supporting cells for myocardial tissue organization in developing and adult heart. J Cell Mol Med. 2010; 14: 2531-8.
53. Rusu MC, Pop F, Hostiuc S, Curca GC, Jianu AM, Paduraru D. Telocytes form networks in normal cardiac tissues. Histol Histopathol. 2012; 27: 807-16.
54. Zhao B, Chen S, Liu J, et al. Cardiac telocytes were decreased during myocardial infarction and their therapeutic effects for ischaemic heart in rat. J Cell Mol Med 2013; 17: 123-33.
55. Zhou J, Wang Y, Zhu P, et al. Distribution and characteristics of telocytes as nurse cells in the architectural organization of engineered heart tissues. Sci China Life Sci 2014; 57: 241-7.
56. Popescu LM, Gherghiceanu M, Manole CG, Faussone-Pellegrini MS. Cardiac renewing: interstitial Cajal-like cells nurse cardiomyocyte progenitors in epicardial stem cell niches. J Cell Mol Med 2009; 13: 866-86.
57. Gherghiceanu M, Popescu LM. Cardiomyocyte precursors and telocytes in epicardial stem cell niche: electron microscope images. J Cell Mol Med 2010; 14: 871-7.
58. Fertig ET, Gherghiceanu M, Popescu LM. Extracellular vesicles release by cardiac telocytes: electron microscopy and electron tomography. J Cell Mol Med 2014; 18: 1938-43.
59. Miao Q, Shim W, Tee N, et al. iPSC-derived human mesenchymal stem cells improve myocardial strain of infarcted myocardium. J Cell Mol Med 2014; 18: 1644-54.
60. Mazhari R, Hare JM. Mechanisms of action of mesenchymal stem cells in cardiac repair: potential influences on the cardiac stem cell niche. Nat Clin Pract Cardiovasc Med 2007; 4(suppl.1): S21-6.
61. Ausoni S, Sartore S. The cardiovascular unit as a dynamic player in disease and regeneration. Trends Mol Med 2009; 15: 543-52.
62. Zhao B, Liao Z, Chen S, et al. Intramyocardial transplantation of cardiac telocytes decreases myocardial infarction and improves post-infarcted cardiac function in rats. J Cell Mol Med 2014; 18: 780-9.