Telocytes express PDGFRα in the human gastrointestinal tract

Journal of Cellular and Molecular Medicine

Volumn 17, Issue 9, 2013, Pages 1099-1108

  Vannucchi, Maria Giuliana ^a   Traini, Chiara ^a   Manetti, Mirko ^a   Ibba Manneschi, Lidia ^a   Faussone Pellegrini, Maria Simonetta ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

Author keywords

C kit; CD34; Human gastrointestinal tract; Immunohistochemistry; PDGFR ; Telocytes

Indexed keywords

CD34 ANTIGEN; PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR; STEM CELL FACTOR RECEPTOR; UBIQUITIN THIOLESTERASE; UCHL1 PROTEIN, HUMAN;

ADULT; AGED; ARTICLE; C-KIT; CD34; CONNECTIVE TISSUE CELL; CYTOLOGY; GASTROINTESTINAL TRACT; HUMAN; HUMAN GASTROINTESTINAL TRACT; IMMUNOHISTOCHEMISTRY; METABOLISM; MIDDLE AGED; PDGFRΑ; TELOCYTES;

C-KIT; CD34; HUMAN GASTROINTESTINAL TRACT; IMMUNOHISTOCHEMISTRY; PDGFRΑ; TELOCYTES;

ADULT; AGED; ANTIGENS, CD34; CONNECTIVE TISSUE CELLS; GASTROINTESTINAL TRACT; HUMANS; IMMUNOHISTOCHEMISTRY; MIDDLE AGED; PROTO-ONCOGENE PROTEINS C-KIT; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR ALPHA; UBIQUITIN THIOLESTERASE;

EID: 84884785128     PISSN: 15821838     EISSN: None     Source Type: Journal    
DOI: 10.1111/jcmm.12134     Document Type: Article

References (52)

1. Gherghiceanu M, Popescu LM. Interstitial Cajal-like cells (ICLC) in human resting mammary gland stroma. Transmission electron microscope (TEM) identification. J Cell Mol Med. 2005; 9: 893-910.
2. Pieri L, Vannucchi MG, Faussone-Pellegrini MS. Histochemical and ultrastructural characteristics of an interstitial cell type different from ICC and resident in the muscle coat of human gut. J Cell Mol Med. 2008; 12: 1944-55.
3. Popescu LM, Faussone-Pellegrini MS. TELOCYTES - a case of serendipity: the winding way from Interstitial Cells of Cajal (ICC), via Interstitial Cajal-Like Cells (ICLC) to TELOCYTES. J Cell Mol Med. 2010; 14: 729-40.
4. Suciu L, Popescu LM, Gherghiceanu M, et al. Telocytes in human term placenta: morphology and phenotype. Cells Tissues Organs. 2010; 192: 325-39.
5. Popescu LM, Manole CG, Gherghiceanu M, et al. Telocytes in human epicardium. J Cell Mol Med. 2010; 14: 2085-93.
6. Faussone-Pellegrini MS, Popescu LM. Telocytes. Biomol Concepts. 2011; 2: 481-9.
7. Nicolescu MI, Popescu LM. Telocytes in the interstitium of human exocrine pancreas: ultrastructural evidence. Pancreas. 2012; 41: 949-56.
8. Gevaert T, De Vos R, Van Der Aa F, et al. Identification of telocytes in the upper lamina propria of the human urinary tract. J Cell Mol Med. 2012; 16: 2085-93.
9. Cretoiu D, Cretoiu SM, Simionescu AA, et al. Telocytes, a distinct type of cell among the stromal cells present in the lamina propria of jejunum. Histol Histopathol. 2012; 27: 1067-78.
10. Faussone Pellegrini MS, Cortesini C, Romagnoli P. Ultrastruttura della tunica della tunica muscolare della porzione cardiale dell'esofago e dello stomaco umano con particolare referenza alle cosiddette cellule interstiziali del Cajal. Arch Ital Anat Embriol. 1977; 82: 157-77.
11. Thuneberg L. Interstitial cells of Cajal: intestinal pacemaker cells? Adv Anat Embryol Cell Biol. 1982; 71: 1-130.
12. Faussone Pellegrini MS, Cortesini C. Some ultrastructural features of the muscular coat of human small intestine. Acta Anat. 1983; 115: 47-68.
13. Faussone Pellegrini MS, Cortesini C. Ultrastructural peculiarities of the inner portion of the circular layer of colon. I. Research in the human. Acta Anat. 1984; 120: 185-9.
14. Faussone-Pellegrini MS, Pantalone D, Cortesini C. An ultrastructural study of the interstitial cells of Cajal of the human stomach. Submicrosc Cytol Pathol. 1989; 21: 439-60.
15. Rumessen JJ, Thuneberg L. Interstitial cells of Cajal in human small intestine. Ultrastructural identification and organization between the main smooth muscle layers. Gastroenterology. 1991; 100: 1417-31.
16. Faussone-Pellegrini MS, Thuneberg L. Guide to the identification of interstitial cells of Cajal. Microsc Res Tech. 1999; 47: 248-66.
17. Faussone-Pellegrini MS, Cortesini C, Romagnoli P. The ultrastructure of the muscle coat of human gastro-oesophageal junction, with special reference to "interstitial cells of Cajal". Front Neurosci. 2013; 7: 49. Doi: 10.3389/fnins.2013.00049.
18. Sanders KM. A case for interstitial cells of Cajal as pacemakers and mediators of neurotransmission in the gastrointestinal tract. Gastroenterology. 1996; 111: 492-515.
19. Iino S, Horiguchi K, Horiguchi S, et al. c-Kit-negative fibroblast-like cells express platelet-derived growth factor receptor alpha in the murine gastrointestinal musculature. Histochem Cell Biol. 2009; 131: 691-702.
20. Iino S, Nojyo Y. Immunohistochemical demonstration of c-Kit-negative fibroblast-like cells in murine gastrointestinal musculature. Arch Histol Cytol. 2009; 72: 107-15.
21. Kurahashi M, Zheng H, Dwyer L, et al. A functional role for the 'fibroblast-like cells' in gastrointestinal smooth muscles. J Physiol. 2011; 589: 697-710.
22. Cobine CA, Hennig GW, Kurahashi M, et al. Relationship between interstitial cells of Cajal, fibroblast-like cells and inhibitory motor nerves in the internal anal sphincter. Cell Tissue Res. 2011; 344: 17-30.
23. Kurahashi M, Nakano Y, Hennig GW, et al. Platelet derived growth factor receptor α-positive cells in the tunica muscularis of human colon. J Cell Mol Med. 2012; 16: 1397-404.
24. Grover M, Bernard CE, Pasricha PJ, et al. Platelet-derived growth factor receptor α (PDGFRα)-expressing "fibroblast-like cells" in diabetic and idiopathic gastroparesis of humans. Neurogastroenterol Motil. 2012; 24: 844-52.
25. Kurahashi M, Nakano Y, Peri LE, et al. A novel population of subepithelial platelet-derived growth factor receptor α-positive cells in the mouse and human colon. Am J Physiol Gastrointest Liver Physiol. 2013; 304: G823-834.
26. + cells in human intestine are fibroblasts adjacent to, but distinct from, interstitial cells of Cajal. Lab Invest. 1999; 79: 59-65.
27. Vanderwinden JM, Rumessen JJ, De Laet MH, et al. CD34 immunoreactivity and interstitial cells of Cajal in the human and mouse gastrointestinal tract. Cell Tissue Res. 2000; 302: 145-53.
28. + channel, in the gut musculature in health and disease. Cell Tissue Res. 2002; 310: 349-58.
29. + channel (SK2 and SK3) immunoreactivity in intestinal smooth muscles of the guinea-pig. Clin Exp Pharmacol Physiol. 2002; 29: 18-25.
30. + channel, SK3, in fibroblast-like cells forming gap junctions with smooth muscle cells in the mouse small intestine. J Pharmacol Sci. 2003; 92: 35-42.
31. Chan F, Liu Y, Sun H, et al. Distribution and possible role of PDGF-AA and PDGFR-alpha in the gastrointestinal tract of adult guinea pigs. Virchows Arch. 2010; 457: 381-8.
32. Cantarero Carmona I, Luesma Bartolomé MJ, Junquera Escribano C. Identification of telocytes in the lamina propria of rat duodenum: transmission electron microscopy. J Cell Mol Med. 2011; 15: 26-30.
33. Iino S, Horiguchi K, Nojyo Y. Interstitial cells of Cajal are innervated by nitrergic nerves and express nitric oxide-sensitive guanylate cyclase in the guinea-pig gastrointestinal tract. Neuroscience. 2008; 152: 43-8.
34. Groneberg D, Konig P, Koesling D, et al. Nitric oxide-sensitive guanylyl cyclase is dispensable for nitrergic signaling and gut motility in mouse intestinal smooth muscle. Gastroenterology. 2011; 140: 1608-17.
35. Faussone-Pellegrini MS, Bani D. Relationships between telocytes and cardiomyocytes during pre- and post-natal life. J Cell Mol Med. 2010; 14: 1061-3.
36. Bani D, Formigli L, Gherghiceanu M, et al. Telocytes as supporting cells for myocardial tissue organization in developing and adult heart. J Cell Mol Med. 2010; 14: 2531-8.
37. Hoch RV, Soriano P. Roles of PDGF in animal development. Development. 2003; 130: 4769-84.
38. Andrae J, Gallini R, Betsholtz C. Role of platelet-derived growth factors in physiology and medicine. Genes Dev. 2008; 22: 1276-312.
39. Karlsson L, Lindahl P, Heath JK, et al. Abnormal gastrointestinal development in PDGF-A and PDGFR-(alpha) deficient mice implicates a novel mesenchymal structure with putative instructive properties in villus morphogenesis. Development. 2000; 127: 457-66.
40. Kurahashi M, Niwa Y, Cheng J, et al. Platelet-derived growth factor signals play critical roles in differentiation of longitudinal smooth muscle cells in mouse embryonic gut. Neurogastroenterol Motil. 2008; 20: 521-31.
41. Popescu LM. The Tandem: telocytes - stem cells. Int J Biol Biomed Eng. 2011; 5: 83-92.
42. Popescu LM, Gherghiceanu M, Suciu LC, et al. Telocytes and putative stem cells in the lungs: electron microscopy, electron tomography and laser scanning microscopy. Cell Tissue Res. 2011; 345: 391-403.
43. Popescu LM, Manole E, Serboiu CS, et al. Identification of telocytes in skeletal muscle interstitium: implication for muscle regeneration. J Cell Mol Med. 2011; 15: 1379-92.
44. Ceafalan L, Gherghiceanu M, Popescu LM, et al. Telocytes in human skin-are they involved in skin regeneration? J Cell Mol Med. 2012; 16: 1405-20.
45. Furuya K, Sokabe M, Furuya S. Characteristics of subepithelial fibroblasts as a mechano-sensor in the intestine: cell-shape-dependent ATP release and P2Y1 signaling. J Cell Sci. 2005; 118: 3289-304.
46. Kaye GI, Lane N, Pascal RR. Colonic pericryptal fibroblast sheath: replication, migration, and cytodifferentiation of a mesenchimal cell system in adult tissue. II. Fine structural aspects of normal rabbit and human colon. Gastroenterology. 1968; 54: 852-65.
47. Rosenbaum ST, Svalø J, Nielsen K, et al. Immunolocalization and expression of small-conductance calcium-activated potassium channels in human myometrium. J Cell Mol Med. 2012; 16: 3001-8.
48. Suciu LC, Popescu BO, Kostin S, et al. Platelet-derived growth factor receptor-β-positive telocytes in skeletal muscle interstitium. J Cell Mol Med. 2012; 16: 701-7.
49. Manetti M, Guiducci S, Ruffo M, et al. Evidence for progressive reduction and loss of telocytes in the dermal cellular network of systemic sclerosis. J Cell Mol Med. 2013; 17: 482-96.
50. Zhao B, Chen S, Liu J, et al. Cardiac telocytes were decreased during myocardial infarction and their therapeutic effects for ischaemic heart in rat. J Cell Mol Med. 2013; 17: 123-33.
51. van Roeven CR, Ostendorf T, Denecke B, et al. Biological responses to PDGF-BB versus PDGF-DD in human mesangial cells. Kidney Int. 2006; 69: 1393-402.
52. Chen SW, Chen YX, Zhang XR, et al. Targeted inhibition of platelet-derived growth factor receptor-beta subunit in hepatic stellate cells ameliorates. Gene Ther. 2008; 15: 1424-35.