메뉴 건너뛰기




Volumn 127, Issue 20, 2016, Pages 2481-2488

Clinical and laboratory variability in a cohort of patients diagnosed with type 1 VWD in the United States

(25)  Flood, Veronica H a,b,c   Christopherson, Pamela A c   Gill, Joan Cox a,b,c   Friedman, Kenneth D a,c   Haberichter, Sandra L a,b,c   Bellissimo, Daniel B c   Udani, Rupa A c   Dasgupta, Mahua a   Hoffmann, Raymond G a   Ragni, Margaret V d   Shapiro, Amy D e   Lusher, Jeanne M f   Lentz, Steven R g   Abshire, Thomas C a,b,c,h   Leissinger, Cindy i   Hoots, W Keith j   Manco Johnson, Marilyn J k   Gruppo, Ralph A l   Boggio, Lisa N m   Montgomery, Kate T n   more..


Author keywords

[No Author keywords available]

Indexed keywords

RISTOCETIN; VON WILLEBRAND FACTOR; VON WILLEBRAND ANTIGEN;

EID: 84974556876     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2015-10-673681     Document Type: Article
Times cited : (105)

References (46)
  • 1
    • 73049112574 scopus 로고    scopus 로고
    • The prevalence of symptomatic von Willebrand disease in primary care practice
    • Bowman M, Hopman WM, Rapson D, Lillicrap D, James P. The prevalence of symptomatic von Willebrand disease in primary care practice. J Thromb Haemost. 2010;8(1):213-216.
    • (2010) J Thromb Haemost , vol.8 , Issue.1 , pp. 213-216
    • Bowman, M.1    Hopman, W.M.2    Rapson, D.3    Lillicrap, D.4    James, P.5
  • 2
    • 0023164845 scopus 로고
    • Epidemiological investigation of the prevalence of von Willebrand's disease
    • Rodeghiero F, Castaman G, Dini E. Epidemiological investigation of the prevalence of von Willebrand's disease. Blood. 1987;69(2):454-459.
    • (1987) Blood , vol.69 , Issue.2 , pp. 454-459
    • Rodeghiero, F.1    Castaman, G.2    Dini, E.3
  • 4
    • 0037443406 scopus 로고    scopus 로고
    • Von Willebrand disease type 1: A diagnosis in search of a disease
    • Sadler JE. Von Willebrand disease type 1: a diagnosis in search of a disease. Blood. 2003;101(6):2089-2093.
    • (2003) Blood , vol.101 , Issue.6 , pp. 2089-2093
    • Sadler, J.E.1
  • 5
    • 13244262641 scopus 로고    scopus 로고
    • Slippery criteria for von Willebrand disease type 1
    • Sadler JE. Slippery criteria for von Willebrand disease type 1. J Thromb Haemost. 2004;2(10):1720-1723.
    • (2004) J Thromb Haemost , vol.2 , Issue.10 , pp. 1720-1723
    • Sadler, J.E.1
  • 6
    • 84868143302 scopus 로고    scopus 로고
    • The evolution and value of bleeding assessment tools
    • Rydz N, James PD. The evolution and value of bleeding assessment tools. J Thromb Haemost. 2012;10(11):2223-2229.
    • (2012) J Thromb Haemost , vol.10 , Issue.11 , pp. 2223-2229
    • Rydz, N.1    James, P.D.2
  • 7
    • 0023150449 scopus 로고
    • A sensitive ELISA for von Willebrand factor (vWf:Ag)
    • Ingerslev J. A sensitive ELISA for von Willebrand factor (vWf:Ag). Scand J Clin Lab Invest. 1987;47(2):143-149.
    • (1987) Scand J Clin Lab Invest. , vol.47 , Issue.2 , pp. 143-149
    • Ingerslev, J.1
  • 8
    • 0015624119 scopus 로고
    • Ristocetin: A means of differentiating von Willebrand's disease into two groups
    • Howard MA, Sawers RJ, Firkin BG. Ristocetin: a means of differentiating von Willebrand's disease into two groups. Blood. 1973;41(5):687-690.
    • (1973) Blood , vol.41 , Issue.5 , pp. 687-690
    • Howard, M.A.1    Sawers, R.J.2    Firkin, B.G.3
  • 9
    • 83055187115 scopus 로고    scopus 로고
    • Von Willebrand disease (VWD): Evidence-based diagnosis and management guidelines, the National Heart, Lung, and Blood Institute (NHLBI) Expert Panel report (USA)
    • Nichols WL, Hultin MB, James AH, et al. von Willebrand disease (VWD): evidence-based diagnosis and management guidelines, the National Heart, Lung, and Blood Institute (NHLBI) Expert Panel report (USA). Haemophilia. 2008;14(2):171-232.
    • (2008) Haemophilia , vol.14 , Issue.2 , pp. 171-232
    • Nichols, W.L.1    Hultin, M.B.2    James, A.H.3
  • 10
    • 34147188129 scopus 로고    scopus 로고
    • Impact of plasma von Willebrand factor levels in the diagnosis of type 1 von Willebrand disease: Results from a multicenter European study (MCMDM-1VWD)
    • Tosetto A, Rodeghiero F, Castaman G, et al. Impact of plasma von Willebrand factor levels in the diagnosis of type 1 von Willebrand disease: results from a multicenter European study (MCMDM-1VWD). J Thromb Haemost. 2007;5(4):715-721.
    • (2007) J Thromb Haemost , vol.5 , Issue.4 , pp. 715-721
    • Tosetto, A.1    Rodeghiero, F.2    Castaman, G.3
  • 11
    • 84905675810 scopus 로고    scopus 로고
    • Quantitative impact of using different criteria for the laboratory diagnosis of type 1 von Willebrand disease
    • Quiroga T, Goycoolea M, Belmont S, et al. Quantitative impact of using different criteria for the laboratory diagnosis of type 1 von Willebrand disease. J Thromb Haemost. 2014;12(8):1238-1243.
    • (2014) J Thromb Haemost , vol.12 , Issue.8 , pp. 1238-1243
    • Quiroga, T.1    Goycoolea, M.2    Belmont, S.3
  • 12
    • 33751219230 scopus 로고    scopus 로고
    • An investigation of the von Willebrand factor genotype in UK patients diagnosed to have type 1 von Willebrand disease
    • UK Haemophilia Centre Doctors' Organisation
    • Cumming A, Grundy P, Keeney S, et al; UK Haemophilia Centre Doctors' Organisation. An investigation of the von Willebrand factor genotype in UK patients diagnosed to have type 1 von Willebrand disease. Thromb Haemost. 2006;96(5):630-641.
    • (2006) Thromb Haemost , vol.96 , Issue.5 , pp. 630-641
    • Cumming, A.1    Grundy, P.2    Keeney, S.3
  • 13
    • 33846026307 scopus 로고    scopus 로고
    • The mutational spectrum of type 1 von Willebrand disease: Results from a Canadian cohort study
    • James PD, Notley C, Hegadorn C, et al. The mutational spectrum of type 1 von Willebrand disease: results from a Canadian cohort study. Blood. 2007;109(1):145-154.
    • (2007) Blood , vol.109 , Issue.1 , pp. 145-154
    • James, P.D.1    Notley, C.2    Hegadorn, C.3
  • 14
    • 33845967766 scopus 로고    scopus 로고
    • Phenotype and genotype of a cohort of families historically diagnosed with type 1 von Willebrand disease in the European study, Molecular and Clinical Markers for the Diagnosis and Management of Type 1 von Willebrand Disease (MCMDM-1VWD)
    • Goodeve A, Eikenboom J, Castaman G, et al. Phenotype and genotype of a cohort of families historically diagnosed with type 1 von Willebrand disease in the European study, Molecular and Clinical Markers for the Diagnosis and Management of Type 1 von Willebrand Disease (MCMDM-1VWD). Blood. 2007;109(1):112-121.
    • (2007) Blood , vol.109 , Issue.1 , pp. 112-121
    • Goodeve, A.1    Eikenboom, J.2    Castaman, G.3
  • 15
    • 77956493323 scopus 로고    scopus 로고
    • ISTH/SSC bleeding assessment tool: A standardized questionnaire and a proposal for a new bleeding score for inherited bleeding disorders
    • Rodeghiero F, Tosetto A, Abshire T, et al; ISTH/SSC Joint VWF and Perinatal/Pediatric Hemostasis Subcommittees Working Group. ISTH/SSC bleeding assessment tool: a standardized questionnaire and a proposal for a new bleeding score for inherited bleeding disorders. J Thromb Haemost. 2010;8(9):2063-2065.
    • (2010) J Thromb Haemost , vol.8 , Issue.9 , pp. 2063-2065
    • Rodeghiero, F.1    Tosetto, A.2    Abshire, T.3
  • 16
    • 77955499972 scopus 로고    scopus 로고
    • Common VWF exon 28 polymorphisms in African Americans affecting the VWF activity assay by ristocetin cofactor
    • Flood VH, Gill JC, Morateck PA, et al. Common VWF exon 28 polymorphisms in African Americans affecting the VWF activity assay by ristocetin cofactor. Blood. 2010;116(2):280-286.
    • (2010) Blood , vol.116 , Issue.2 , pp. 280-286
    • Flood, V.H.1    Gill, J.C.2    Morateck, P.A.3
  • 17
    • 0014072767 scopus 로고
    • A semiautomatic one-stage factor 8 assay with a commercially prepared standard
    • Simone JV, Vanderheiden J, Abildgaard CF. A semiautomatic one-stage factor 8 assay with a commercially prepared standard. J Lab Clin Med. 1967;69(4):706-712.
    • (1967) J Lab Clin Med. , vol.69 , Issue.4 , pp. 706-712
    • Simone, J.V.1    Vanderheiden, J.2    Abildgaard, C.F.3
  • 18
    • 84861068515 scopus 로고    scopus 로고
    • Intersection of mechanisms of type 2A VWD through defects in VWF multimerization, secretion, ADAMTS-13 susceptibility, and regulated storage
    • Jacobi PM, Gill JC, Flood VH, Jakab DA, Friedman KD, Haberichter SL. Intersection of mechanisms of type 2A VWD through defects in VWF multimerization, secretion, ADAMTS-13 susceptibility, and regulated storage. Blood. 2012;119(19):4543-4553.
    • (2012) Blood , vol.119 , Issue.19 , pp. 4543-4553
    • Jacobi, P.M.1    Gill, J.C.2    Flood, V.H.3    Jakab, D.A.4    Friedman, K.D.5    Haberichter, S.L.6
  • 19
    • 84926664083 scopus 로고    scopus 로고
    • Crucial role for the VWF A1 domain in binding to type IV collagen
    • Zimmerman Program Investigators
    • Flood VH, Schlauderaff AC, Haberichter SL, et al; Zimmerman Program Investigators. Crucial role for the VWF A1 domain in binding to type IV collagen. Blood. 2015;125(14):2297-2304.
    • (2015) Blood , vol.125 , Issue.14 , pp. 2297-2304
    • Flood, V.H.1    Schlauderaff, A.C.2    Haberichter, S.L.3
  • 20
    • 79951469339 scopus 로고    scopus 로고
    • Gain-of-function GPIb ELISA assay for VWF activity in the Zimmerman program for the molecular and clinical biology of VWD
    • Flood VH, Gill JC, Morateck PA, et al. Gain-of-function GPIb ELISA assay for VWF activity in the Zimmerman program for the molecular and clinical biology of VWD. Blood. 2011;117(6):e67-e74.
    • (2011) Blood , vol.117 , Issue.6 , pp. e67-e74
    • Flood, V.H.1    Gill, J.C.2    Morateck, P.A.3
  • 21
    • 84935687838 scopus 로고    scopus 로고
    • Platelet-dependent von Willebrand factor activity. Nomenclature and methodology: Communication from the SSC of the ISTH
    • Subcommittee on von Willebrand factor
    • Bodó I, Eikenboom J, Montgomery R, Patzke J, Schneppenheim R, Di Paola J; Subcommittee on von Willebrand factor. Platelet-dependent von Willebrand factor activity. Nomenclature and methodology: communication from the SSC of the ISTH. J Thromb Haemost. 2015;13(7):1345-1350.
    • (2015) J Thromb Haemost , vol.13 , Issue.7 , pp. 1345-1350
    • Bodó, I.1    Eikenboom, J.2    Montgomery, R.3    Patzke, J.4    Schneppenheim, R.5    Di Paola, J.6
  • 22
    • 33751013939 scopus 로고    scopus 로고
    • Assay of the von Willebrand factor (VWF) propeptide to identify patients with type 1 von Willebrand disease with decreased VWF survival
    • Haberichter SL, Balistreri M, Christopherson P, et al. Assay of the von Willebrand factor (VWF) propeptide to identify patients with type 1 von Willebrand disease with decreased VWF survival. Blood. 2006;108(10):3344-3351.
    • (2006) Blood , vol.108 , Issue.10 , pp. 3344-3351
    • Haberichter, S.L.1    Balistreri, M.2    Christopherson, P.3
  • 23
    • 84857720362 scopus 로고    scopus 로고
    • VWF mutations and new sequence variations identified in healthy controls are more frequent in the African-American population
    • Bellissimo DB, Christopherson PA, Flood VH, et al. VWF mutations and new sequence variations identified in healthy controls are more frequent in the African-American population. Blood. 2012;119(9):2135-2140.
    • (2012) Blood , vol.119 , Issue.9 , pp. 2135-2140
    • Bellissimo, D.B.1    Christopherson, P.A.2    Flood, V.H.3
  • 24
    • 84889054093 scopus 로고    scopus 로고
    • Detection limit of intragenic deletions with targeted array comparative genomic hybridization
    • Askree SH, Chin EL, Bean LH, Coffee B, Tanner A, Hegde M. Detection limit of intragenic deletions with targeted array comparative genomic hybridization. BMC Genet. 2013;14:116.
    • (2013) BMC Genet. , vol.14 , pp. 116
    • Askree, S.H.1    Chin, E.L.2    Bean, L.H.3    Coffee, B.4    Tanner, A.5    Hegde, M.6
  • 25
    • 84930351608 scopus 로고    scopus 로고
    • Solving the molecular diagnostic testing conundrum for Mendelian disorders in the era of next-generation sequencing: Single-gene, gene panel, or exome/genome sequencing
    • Xue Y, Ankala A, Wilcox WR, Hegde MR. Solving the molecular diagnostic testing conundrum for Mendelian disorders in the era of next-generation sequencing: single-gene, gene panel, or exome/genome sequencing. Genet Med. 2015;17(6):444-451.
    • (2015) Genet Med. , vol.17 , Issue.6 , pp. 444-451
    • Xue, Y.1    Ankala, A.2    Wilcox, W.R.3    Hegde, M.R.4
  • 26
    • 46749133213 scopus 로고    scopus 로고
    • Identification of type 1 von Willebrand disease patients with reduced von Willebrand factor survival by assay of the VWF propeptide in the European study: Molecular and clinical markers for the diagnosis and management of type 1 VWD (MCMDM-1VWD)
    • Haberichter SL, Castaman G, Budde U, et al. Identification of type 1 von Willebrand disease patients with reduced von Willebrand factor survival by assay of the VWF propeptide in the European study: molecular and clinical markers for the diagnosis and management of type 1 VWD (MCMDM-1VWD). Blood. 2008;111(10):4979-4985.
    • (2008) Blood , vol.111 , Issue.10 , pp. 4979-4985
    • Haberichter, S.L.1    Castaman, G.2    Budde, U.3
  • 27
    • 85019848943 scopus 로고    scopus 로고
    • Spectrum of type 2 von Willebrand disease in the Zimmerman program
    • abstract
    • Flood VH, Christopherson PA, Bellissimo DB, et al. Spectrum of type 2 von Willebrand disease in the Zimmerman program [abstract]. Blood. 2014;124(21). Abstract 472.
    • (2014) Blood , vol.124 , Issue.21
    • Flood, V.H.1    Christopherson, P.A.2    Bellissimo, D.B.3
  • 28
    • 84942517095 scopus 로고    scopus 로고
    • Normal range of bleeding scores for the ISTH-BAT: Adult and pediatric data from the merging project
    • Zimmerman Program Investigators
    • Elbatarny M, Mollah S, Grabell J, et al; Zimmerman Program Investigators. Normal range of bleeding scores for the ISTH-BAT: adult and pediatric data from the merging project. Haemophilia. 2014;20(6):831-835.
    • (2014) Haemophilia , vol.20 , Issue.6 , pp. 831-835
    • Elbatarny, M.1    Mollah, S.2    Grabell, J.3
  • 29
    • 77954496769 scopus 로고    scopus 로고
    • Absent collagen binding in a VWF A3 domain mutant: Utility of the VWF:CB in diagnosis of VWD
    • Flood VH, Lederman CA, Wren JS, et al. Absent collagen binding in a VWF A3 domain mutant: utility of the VWF:CB in diagnosis of VWD. J Thromb Haemost. 2010;8(6):1431-1433.
    • (2010) J Thromb Haemost , vol.8 , Issue.6 , pp. 1431-1433
    • Flood, V.H.1    Lederman, C.A.2    Wren, J.S.3
  • 30
    • 0023257218 scopus 로고
    • The effect of ABO blood group on the diagnosis of von Willebrand disease
    • Gill JC, Endres-Brooks J, Bauer PJ, Marks WJ Jr, Montgomery RR. The effect of ABO blood group on the diagnosis of von Willebrand disease. Blood. 1987;69(6):1691-1695.
    • (1987) Blood , vol.69 , Issue.6 , pp. 1691-1695
    • Gill, J.C.1    Endres-Brooks, J.2    Bauer, P.J.3    Marks, W.J.4    Montgomery, R.R.5
  • 31
    • 84904249971 scopus 로고    scopus 로고
    • Von Willebrand disease and aging: An evolving phenotype
    • Sanders YV, Giezenaar MA, Laros-van Gorkom BA, et al; WiN study group. von Willebrand disease and aging: an evolving phenotype. J Thromb Haemost. 2014;12(7):1066-1075.
    • (2014) J Thromb Haemost , vol.12 , Issue.7 , pp. 1066-1075
    • Sanders, Y.V.1    Giezenaar, M.A.2    Laros-Van Gorkom, B.A.3
  • 32
    • 84942194089 scopus 로고    scopus 로고
    • Changes in von Willebrand factor level and von Willebrand activity with age in type 1 von Willebrand disease
    • Rydz N, Grabell J, Lillicrap D, James PD. Changes in von Willebrand factor level and von Willebrand activity with age in type 1 von Willebrand disease. Haemophilia. 2015;21(5):636-641.
    • (2015) Haemophilia , vol.21 , Issue.5 , pp. 636-641
    • Rydz, N.1    Grabell, J.2    Lillicrap, D.3    James, P.D.4
  • 33
    • 33746615625 scopus 로고    scopus 로고
    • Laboratory tests for measurement of von Willebrand factor show poor agreement among different centers: Results from the United Kingdom National External Quality Assessment Scheme for Blood Coagulation
    • Kitchen S, Jennings I, Woods TA, Kitchen DP, Walker ID, Preston FE. Laboratory tests for measurement of von Willebrand factor show poor agreement among different centers: results from the United Kingdom National External Quality Assessment Scheme for Blood Coagulation. Semin Thromb Hemost. 2006;32(5):492-498.
    • (2006) Semin Thromb Hemost , vol.32 , Issue.5 , pp. 492-498
    • Kitchen, S.1    Jennings, I.2    Woods, T.A.3    Kitchen, D.P.4    Walker, I.D.5    Preston, F.E.6
  • 34
    • 33746644201 scopus 로고    scopus 로고
    • An external quality assessment program for von Willebrand factor laboratory analysis: An overview from the European concerted action on thrombosis and disabilities foundation
    • Meijer P, Haverkate F. An external quality assessment program for von Willebrand factor laboratory analysis: an overview from the European concerted action on thrombosis and disabilities foundation. Semin Thromb Hemost. 2006;32(5):485-491.
    • (2006) Semin Thromb Hemost , vol.32 , Issue.5 , pp. 485-491
    • Meijer, P.1    Haverkate, F.2
  • 36
    • 84884180924 scopus 로고    scopus 로고
    • The C-type lectin receptor CLEC4M binds, internalizes, and clears von Willebrand factor and contributes to the variation in plasma von Willebrand factor levels
    • Rydz N, Swystun LL, Notley C, et al. The C-type lectin receptor CLEC4M binds, internalizes, and clears von Willebrand factor and contributes to the variation in plasma von Willebrand factor levels. Blood. 2013;121(26):5228-5237.
    • (2013) Blood , vol.121 , Issue.26 , pp. 5228-5237
    • Rydz, N.1    Swystun, L.L.2    Notley, C.3
  • 37
    • 84930180243 scopus 로고    scopus 로고
    • CLEC4M and STXBP5 gene variations contribute to von Willebrand factor level variation in von Willebrand disease
    • Sanders YV, van der Bom JG, Isaacs A, et al; WiN Study Group. CLEC4M and STXBP5 gene variations contribute to von Willebrand factor level variation in von Willebrand disease. J Thromb Haemost. 2015;13(6):956-966.
    • (2015) J Thromb Haemost , vol.13 , Issue.6 , pp. 956-966
    • Sanders, Y.V.1    Van Der Bom, J.G.2    Isaacs, A.3
  • 38
    • 84872180690 scopus 로고    scopus 로고
    • Linkage analysis identifies a locus for plasma von Willebrand factor undetected by genome-wide association
    • Desch KC, Ozel AB, Siemieniak D, et al. Linkage analysis identifies a locus for plasma von Willebrand factor undetected by genome-wide association. Proc Natl Acad Sci USA. 2013;110(2):588-593.
    • (2013) Proc Natl Acad Sci USA , vol.110 , Issue.2 , pp. 588-593
    • Desch, K.C.1    Ozel, A.B.2    Siemieniak, D.3
  • 39
    • 84867246111 scopus 로고    scopus 로고
    • Mutation distribution in the von Willebrand factor gene related to the different von Willebrand disease (VWD) types in a cohort of VWD patients
    • Yadegari H, Driesen J, Pavlova A, Biswas A, Hertfelder HJ, Oldenburg J. Mutation distribution in the von Willebrand factor gene related to the different von Willebrand disease (VWD) types in a cohort of VWD patients. Thromb Haemost. 2012;108(4):662-671.
    • (2012) Thromb Haemost , vol.108 , Issue.4 , pp. 662-671
    • Yadegari, H.1    Driesen, J.2    Pavlova, A.3    Biswas, A.4    Hertfelder, H.J.5    Oldenburg, J.6
  • 40
    • 56749160315 scopus 로고    scopus 로고
    • Generation and validation of the condensed MCMDM-1VWD bleeding questionnaire for von Willebrand disease
    • Bowman M, Mundell G, Grabell J, et al. Generation and validation of the condensed MCMDM-1VWD bleeding questionnaire for von Willebrand disease. J Thromb Haemost. 2008;6(12):2062-2066.
    • (2008) J Thromb Haemost , vol.6 , Issue.12 , pp. 2062-2066
    • Bowman, M.1    Mundell, G.2    Grabell, J.3
  • 41
    • 43249098361 scopus 로고    scopus 로고
    • Evidence-based diagnosis of type 1 von Willebrand disease: A Bayes theorem approach
    • Tosetto A, Castaman G, Rodeghiero F. Evidence-based diagnosis of type 1 von Willebrand disease: a Bayes theorem approach. Blood. 2008;111(8):3998-4003.
    • (2008) Blood , vol.111 , Issue.8 , pp. 3998-4003
    • Tosetto, A.1    Castaman, G.2    Rodeghiero, F.3
  • 42
    • 84880611860 scopus 로고    scopus 로고
    • Bleeders, bleeding rates, and bleeding score
    • Tosetto A, Castaman G, Rodeghiero F. Bleeders, bleeding rates, and bleeding score. J Thromb Haemost. 2013;11(suppl 1):142-150.
    • (2013) J Thromb Haemost , vol.11 , pp. 142-150
    • Tosetto, A.1    Castaman, G.2    Rodeghiero, F.3
  • 43
    • 84898678042 scopus 로고    scopus 로고
    • Evaluation of an automated method for measuring von Willebrand factor activity in clinical samples without ristocetin
    • Graf L, Moffat KA, Carlino SA, et al. Evaluation of an automated method for measuring von Willebrand factor activity in clinical samples without ristocetin. Int J Lab Hematol. 2014;36(3):341-351.
    • (2014) Int J Lab Hematol. , vol.36 , Issue.3 , pp. 341-351
    • Graf, L.1    Moffat, K.A.2    Carlino, S.A.3
  • 45
    • 33644977050 scopus 로고    scopus 로고
    • A quantitative analysis of bleeding symptoms in type 1 von Willebrand disease: Results from a multicenter European study (MCMDM-1 VWD)
    • Tosetto A, Rodeghiero F, Castaman G, et al. A quantitative analysis of bleeding symptoms in type 1 von Willebrand disease: results from a multicenter European study (MCMDM-1 VWD). J Thromb Haemost. 2006;4(4):766-773.
    • (2006) J Thromb Haemost , vol.4 , Issue.4 , pp. 766-773
    • Tosetto, A.1    Rodeghiero, F.2    Castaman, G.3
  • 46
    • 84903647813 scopus 로고    scopus 로고
    • The bleeding score predicts clinical outcomes and replacement therapy in adults with von Willebrand disease
    • Federici AB, Bucciarelli P, Castaman G, et al. The bleeding score predicts clinical outcomes and replacement therapy in adults with von Willebrand disease. Blood. 2014;123(26):4037-4044.
    • (2014) Blood , vol.123 , Issue.26 , pp. 4037-4044
    • Federici, A.B.1    Bucciarelli, P.2    Castaman, G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.