The C-type lectin receptor CLEC4M binds, internalizes, and clears von Willebrand factor and contributes to the variation in plasma von Willebrand factor levels

Blood

Volumn 121, Issue 6, 2013, Pages 5228-5237

  Rydz, Natalia ^a   Swystun, Laura L ^a   Notley, Colleen ^a   Paterson, Andrew D ^b   Riches, J Jacob ^a   Sponagle, Kate ^a   Boonyawat, Boonchai ^b   Montgomery, Robert R ^c   James, Paula D ^a   Lillicrap, David ^a  

^a QUEEN S UNIVERSITY   (Canada)

^b HOSPITAL FOR SICK CHILDREN   (Canada)

^c MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

C TYPE LECTIN DOMAIN FAMILY 4 MEMBER M; LECTIN RECEPTOR; UNCLASSIFIED DRUG; VON WILLEBRAND FACTOR; DNA; LECTIN;

ADOLESCENT; ADULT; ALLELE; ANIMAL EXPERIMENT; ARTICLE; CHILD; CLEARANCE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENETIC POLYMORPHISM; GENOTYPE; HEK293 CELL LINE; HUMAN; IMMUNOFLUORESCENCE; IN VITRO STUDY; IN VIVO STUDY; INTERNALIZATION; MAJOR CLINICAL STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN BLOOD LEVEL; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; VARIABLE NUMBER OF TANDEM REPEAT; VON WILLEBRAND DISEASE; ANIMAL; BLOOD; CASE CONTROL STUDY; CELL STRAIN HEK293; COMPARATIVE STUDY; ENZYME IMMUNOASSAY; FAMILY; FEMALE; FLOW CYTOMETRY; GENE LINKAGE DISEQUILIBRIUM; GENETIC ASSOCIATION; GENETICS; INFANT; LIVER; MALE; METABOLISM; MIDDLE AGED; PATHOLOGY; POLYMERASE CHAIN REACTION; PRESCHOOL CHILD;

ADOLESCENT; ADULT; ANIMALS; CASE-CONTROL STUDIES; CHILD; CHILD, PRESCHOOL; DNA; ENZYME-LINKED IMMUNOSORBENT ASSAY; FAMILY; FEMALE; FLOW CYTOMETRY; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HEK293 CELLS; HUMANS; IMMUNOENZYME TECHNIQUES; INFANT; LECTINS, C-TYPE; LINKAGE DISEQUILIBRIUM; LIVER; MALE; MICE; MIDDLE AGED; MINISATELLITE REPEATS; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; VON WILLEBRAND DISEASES; VON WILLEBRAND FACTOR; YOUNG ADULT;

EID: 84884180924     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2012-10-457507     Document Type: Article

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