Large Porous Particles for Sustained Release of a Decoy Oligonucelotide and Poly(ethylenimine): Potential for Combined Therapy of Chronic Pseudomonas aeruginosa Lung Infections

Biomacromolecules

Volumn 17, Issue 5, 2016, Pages 1561-1571

  D'Angelo, Ivana ^a   Perfetto, Brunella ^a   Costabile, Gabriella ^b   Ambrosini, Veronica ^a   Caputo, Pina ^a   Miro, Agnese ^b   D'Emmanuele Di Villa Bianca, Roberta ^b   Sorrentino, Raffaella ^b   Donnarumma, Giovanna ^a   Quaglia, Fabiana ^b   Ungaro, Francesca ^b  

^a SECOND UNIVERSITY OF NAPLES   (Italy)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTICS; BACTERIA; CYTOTOXICITY; DISEASE CONTROL; DRUG PRODUCTS; OLIGONUCLEOTIDES; PATHOLOGY; POROUS MATERIALS;

ANTI-INFLAMMATORY DRUGS; ANTI-MICROBIAL ACTIVITY; CHRONIC INFLAMMATION; MINIMUM INHIBITORY CONCENTRATION; MULTIFUNCTIONAL SYSTEMS; POLY(LACTIC-CO-GLYCOLIC ACID); PSEUDOMONAS AERUGINOSA; TECHNOLOGICAL PROPERTIES;

BIOLOGICAL ORGANS;

AZTREONAM; DECOY OLIGONUCLEOTIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; OLIGONUCLEOTIDE; POLYETHYLENEIMINE; POLYGLACTIN; TOBRAMYCIN; UNCLASSIFIED DRUG; DRUG CARRIER; LACTIC ACID; POLYGLYCOLIC ACID; POLYLACTIC ACID-POLYGLYCOLIC ACID COPOLYMER;

AEROSOL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBIOTIC SENSITIVITY; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRY POWDER; ENCAPSULATION; EPITHELIUM BASAL CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; LUNG FIBROSIS; LUNG INFECTION; MALE; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PARTICLE SIZE; POROSITY; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; RAT; SUSTAINED DRUG RELEASE; ANIMAL; CHEMISTRY; CHRONIC DISEASE; DRUG EFFECTS; MICROBIOLOGY; PSEUDOMONAS INFECTIONS; RESPIRATORY TRACT INFECTIONS; WISTAR RAT;

ANIMALS; CHRONIC DISEASE; DRUG CARRIERS; HUMANS; LACTIC ACID; MALE; OLIGONUCLEOTIDES; POLYETHYLENEIMINE; POLYGLYCOLIC ACID; POROSITY; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTIONS; RATS; RATS, WISTAR; RESPIRATORY TRACT INFECTIONS;

EID: 84973635859     PISSN: 15257797     EISSN: 15264602     Source Type: Journal    
DOI: 10.1021/acs.biomac.5b01646     Document Type: Article

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