Relationship of Insulin Resistance to Prevalence and Progression of Coronary Artery Calcification beyond Metabolic Syndrome Components

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 36, Issue 8, 2016, Pages 1703-1708

  Yamazoe, Masahiro ^a,b   Hisamatsu, Takashi ^b,c   Miura, Katsuyuki ^b   Kadowaki, Sayaka ^b   Zaid, Maryam ^b   Kadota, Aya ^b   Torii, Sayuki ^b   Miyazawa, Itsuko ^b   Fujiyoshi, Akira ^b   Arima, Hisatomi ^b,d   Sekikawa, Akira ^e   Maegawa, Hiroshi ^b   Horie, Minoru ^b   Ueshima, Hirotsugu ^b  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^b SHIGA UNIVERSITY OF MEDICAL SCIENCE   (Japan)

^c SHIMANE UNIVERSITY   (Japan)

^d FUKUOKA UNIVERSITY   (Japan)

^e UNIVERSITY OF PITTSBURGH GRADUATE SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

atherosclerosis; coronary artery calcification; epidemiology; insulin resistance; metabolic syndrome

Indexed keywords

GLUCOSE; HEMOGLOBIN A1C; INSULIN; BIOLOGICAL MARKER; GLUCOSE BLOOD LEVEL; GLYCOSYLATED HEMOGLOBIN; HEMOGLOBIN A1C PROTEIN, HUMAN;

ADULT; AGED; ARTICLE; ATHEROSCLEROSIS; CORONARY ARTERY CALCIFICATION; DIABETES MELLITUS; DISEASE ASSOCIATION; DISEASE COURSE; DISEASE DURATION; FOLLOW UP; HUMAN; INSULIN RESISTANCE; JAPANESE (PEOPLE); MAJOR CLINICAL STUDY; MALE; METABOLIC SYNDROME X; POPULATION RESEARCH; PREVALENCE; PRIORITY JOURNAL; ANALYSIS; ASYMPTOMATIC DISEASE; BLOOD; CHI SQUARE DISTRIBUTION; CORONARY ANGIOGRAPHY; CORONARY ARTERY DISEASE; DIAGNOSTIC IMAGING; DIET RESTRICTION; GLUCOSE BLOOD LEVEL; JAPAN; MIDDLE AGED; MULTIDETECTOR COMPUTED TOMOGRAPHY; MULTIVARIATE ANALYSIS; ODDS RATIO; PROCEDURES; RISK ASSESSMENT; RISK FACTOR; STATISTICAL MODEL; VASCULAR CALCIFICATION;

ADULT; AGED; ASYMPTOMATIC DISEASES; BIOMARKERS; BLOOD GLUCOSE; CHI-SQUARE DISTRIBUTION; CORONARY ANGIOGRAPHY; CORONARY ARTERY DISEASE; DISEASE PROGRESSION; FASTING; HEMOGLOBIN A, GLYCOSYLATED; HUMANS; INSULIN; INSULIN RESISTANCE; JAPAN; LOGISTIC MODELS; MALE; METABOLIC SYNDROME X; MIDDLE AGED; MULTIDETECTOR COMPUTED TOMOGRAPHY; MULTIVARIATE ANALYSIS; ODDS RATIO; PREVALENCE; RISK ASSESSMENT; RISK FACTORS; VASCULAR CALCIFICATION;

EID: 84973573762     PISSN: 10795642     EISSN: 15244636     Source Type: Journal    
DOI: 10.1161/ATVBAHA.116.307612     Document Type: Article

References (23)

1. Sarwar N, Gao P, Seshasai SR, et al. Diabetes mellitus, fasting blood glucose concentration, and risk of vascular disease: A collaborative metaanalysis of 102 prospective studies. Lancet. 2010;375:2215-2222
2. Faerch K, Vaag A, Holst JJ, Hansen T, Jørgensen T, Borch-Johnsen K. Natural history of insulin sensitivity and insulin secretion in the progression from normal glucose tolerance to impaired fasting glycemia and impaired glucose tolerance: the Inter99 study. Diabetes Care. 2009;32:439-444. doi: 10. 2337/dc08-1195
3. Kim SH, Reaven GM. Isolated impaired fasting glucose and peripheral insulin sensitivity: not a simple relationship. Diabetes Care. 2008;31:347-352. doi: 10. 2337/dc07-1574
4. Alberti KG, Eckel RH, Grundy SM, Zimmet PZ, Cleeman JI, Donato KA, Fruchart JC, James WP, Loria CM, Smith SC Jr; International Diabetes Federation Task Force on Epidemiology and Prevention; Hational Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; International Association for the Study of Obesity. Harmonizing the metabolic syndrome: a joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity. Circulation. 2009;120:1640-1645. doi: 10. 1161/ CIRCULATIONAHA. 109. 192644
5. Reilly MP, Wolfe ML, Rhodes T, Girman C, Mehta N, Rader DJ. Measures of insulin resistance add incremental value to the clinical diagnosis of metabolic syndrome in association with coronary atherosclerosis. Circulation. 2004;110:803-809. doi: 10. 1161/01. CIR. 0000138740. 84883. 9C
6. Blaha MJ, DeFilippis AP, Rivera JJ, Budoff MJ, Blankstein R, Agatston A, Szklo M, Lakoski SG, Bertoni AG, Kronmal RA, Blumenthal RS, Nasir K. The relationship between insulin resistance and incidence and progression of coronary artery calcification: the Multi-Ethnic Study of Atherosclerosis (MESA). Diabetes Care. 2011;34:749-751. doi: 10. 2337/dc10-1681
7. Arad Y, Newstein D, Cadet F, Roth M, Guerci AD. Association of multiple risk factors and insulin resistance with increased prevalence of asymptomatic coronary artery disease by an electron-beam computed tomographic study. Arterioscler Thromb Vasc Biol. 2001;21:2051-2058
8. Budoff MJ, Young R, Lopez VA, et al. Progression of coronary calcium and incident coronary heart disease events: MESA (Multi-Ethnic Study of Atherosclerosis). J Am Coll Cardiol. 2013;61:1231-1239. doi: 10. 1016/j. jacc. 2012. 12. 035
9. Lee KK, Fortmann SP, Fair JM, Iribarren C, Rubin GD, Varady A, Go AS, Quertermous T, Hlatky MA. Insulin resistance independently predicts the progression of coronary artery calcification. Am Heart J. 2009;157:939-945. doi: 10. 1016/j. ahj. 2009. 02. 006
10. Sung KC, Choi JH, Gwon HC, Choi SH, Kim BS, Kwag HJ, Kim SH. Relationship between insulin resistance and coronary artery calcium in young men and women. PLoS One. 2013;8:e53316. doi: 10. 1371/journal. pone. 0053316
11. Bornfeldt KE, Tabas I. Insulin resistance, hyperglycemia, and atherosclerosis. Cell Metab. 2011;14:575-585. doi: 10. 1016/j. cmet. 2011. 07. 015
12. Giacco F, Brownlee M. Oxidative stress and diabetic complications. Circ Res. 2010;107:1058-1070. doi: 10. 1161/CIRCRESAHA. 110. 223545
13. Zavaroni I, Bonora E, Pagliara M, Dall'Aglio E, Luchetti L, Buonanno G, Bonati PA, Bergonzani M, Gnudi L, Passeri M. Risk factors for coronary artery disease in healthy persons with hyperinsulinemia and normal glucose tolerance. N Engl J Med. 1989;320:702-706. doi: 10. 1056/ NEJM198903163201105
14. Sheu WH, Jeng CY, Young MS, Le WJ, Chen YT. Coronary artery disease risk predicted by insulin resistance, plasma lipids, and hypertension in people without diabetes. Am J Med. Sci. 2000;319:84-88
15. DeFronzo RA. Insulin resistance, lipotoxicity, type 2 diabetes and atherosclerosis: The missing links. The Claude Bernard Lecture 2009. Diabetologia. 2010;53:1270-1287
16. Rask-Madsen C, Li Q, Freund B, et al. Loss of insulin signaling in vascular endothelial cells accelerates atherosclerosis in apolipoprotein E null mice. Cell Metab. 2010;11:379-389. doi: 10. 1016/j. cmet. 2010. 03. 013
17. Budoff MJ, Hokanson JE, Nasir K, Shaw LJ, Kinney GL, Chow D, Demoss D, Nuguri V, Nabavi V, Ratakonda R, Berman DS, Raggi P. Progression of coronary artery calcium predicts all-cause mortality. JACC Cardiovasc Imaging. 2010;3:1229-1236. doi: 10. 1016/j. jcmg. 2010. 08. 018
18. Kronmal RA, McClelland RL, Detrano R, Shea S, Lima JA, Cushman M, Bild DE, Burke GL. Risk factors for the progression of coronary artery calcification in asymptomatic subjects: results from the Multi-Ethnic Study of Atherosclerosis (MESA). Circulation. 2007;115:2722-2730. doi: 10. 1161/CIRCULATIONAHA. 106. 674143
19. Cassidy AE, Bielak LF, Zhou Y, Sheedy PF II, Turner ST, Breen JF, Araoz PA, Kullo IJ, Lin X, Peyser PA. Progression of subclinical coronary atherosclerosis: does obesity make a difference? Circulation. 2005;111:1877-1882. doi: 10. 1161/01. CIR. 0000161820. 40494. 5D
20. Okwuosa TM, Greenland P, Burke GL, Eng J, Cushman M, Michos ED, Ning H, Lloyd-Jones DM. Prediction of coronary artery calcium progression in individuals with low Framingham Risk Score: the Multi-Ethnic Study of Atherosclerosis. JACC Cardiovasc Imaging. 2012;5:144-153. doi: 10. 1016/j. jcmg. 2011. 11. 008
21. Gast KB, Tjeerdema N, Stijnen T, Smit JW, Dekkers OM. Insulin resistance and risk of incident cardiovascular events in adults without diabetes: meta-analysis. PLoS One. 2012;7:e52036. doi: 10. 1371/journal. pone. 0052036
22. McNeely MJ, McClelland RL, Bild DE, Jacobs DR Jr, Tracy RP, Cushman M, Goff DC Jr, Astor BC, Shea S, Siscovick DS. The association between A1C and subclinical cardiovascular disease: the multi-ethnic study of atherosclerosis. Diabetes Care. 2009;32:1727-1733. doi: 10. 2337/ dc09-0074
23. Carson AP, Steffes MW, Carr JJ, Kim Y, Gross MD, Carnethon MR, Reis JP, Loria CM, Jacobs DR Jr, Lewis CE. Hemoglobin a1c and the progression of coronary artery calcification among adults without diabetes. Diabetes Care. 2015;38:66-71. doi: 10. 2337/dc14-0360