Multicenter, prospective trial of selective drain management for pancreatoduodenectomy using risk stratification

Annals of Surgery

Volumn 265, Issue 6, 2017, Pages 1209-1218

  McMillan, Matthew T ^a   Malleo, Giuseppe ^b   Bassi, Claudio ^b   Allegrini, Valentina ^b   Casetti, Luca ^b   Drebin, Jeffrey A ^a   Esposito, Alessandro ^b   Landoni, Luca ^b   Lee, Major K ^a   Pulvirenti, Alessandra ^b   Roses, Robert E ^a   Salvia, Roberto ^b   Vollmer, Charles M ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF VERONA   (Italy)

Author keywords

Amylase; Drain; Fistula Risk Score; Pancreatic fistula; Pancreatoduodenectomy

Indexed keywords

AMYLASE; ANTIBIOTIC AGENT; DRAIN FLUID AMYLASE; INSULIN; OCTREOTIDE; ORAL ANTIDIABETIC AGENT; UNCLASSIFIED DRUG;

ABDOMINAL DRAIN; ABDOMINAL DRAINAGE; ADULT; AGE; AGED; ANTIBIOTIC THERAPY; ARTICLE; BILE LEAKAGE; BILIARY STENT; BILIARY TRACT DISEASE; BLOOD TRANSFUSION; BODY MASS; CHYLE LEAKAGE; CLINICAL DECISION MAKING; CLINICAL EFFECTIVENESS; CLINICAL EVALUATION; COHORT ANALYSIS; CONTROLLED STUDY; DEVICE REMOVAL; DIABETES MELLITUS; DIGESTIVE SYSTEM DISEASE ASSESSMENT; ENTERIC FEEDING; FEMALE; FISTULA RISK SCORE; HIGH RISK PATIENT; HUMAN; INSULIN TREATMENT; LENGTH OF STAY; LOW RISK PATIENT; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; OBSTRUCTIVE JAUNDICE; OUTCOME ASSESSMENT; PANCREAS ADENOCARCINOMA; PANCREAS FISTULA; PANCREATICODUODENECTOMY; PANCREATITIS; PATIENT SAFETY; PERCUTANEOUS DRAINAGE; POSTOPERATIVE PERIOD; PREOPERATIVE EVALUATION; PRIORITY JOURNAL; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; REOPERATION; RISK ASSESSMENT; SEX; TOTAL PARENTERAL NUTRITION; VULNERABLE POPULATION; ADVERSE EFFECTS; CLINICAL PROTOCOL; CLINICAL TRIAL; DEVICES; DRAINAGE; PANCREATIC FISTULA; POSTOPERATIVE CARE; POSTOPERATIVE COMPLICATIONS; PROCEDURES; TIME FACTOR; TREATMENT OUTCOME;

AGED; CLINICAL PROTOCOLS; DEVICE REMOVAL; DRAINAGE; FEMALE; HUMANS; MALE; PANCREATIC FISTULA; PANCREATICODUODENECTOMY; POSTOPERATIVE CARE; POSTOPERATIVE COMPLICATIONS; PROSPECTIVE STUDIES; RISK ASSESSMENT; TIME FACTORS; TREATMENT OUTCOME;

EID: 84973529627     PISSN: 00034932     EISSN: 15281140     Source Type: Journal    
DOI: 10.1097/SLA.0000000000001832     Document Type: Article

References (31)

1. Jeekel J. No abdominal drainage after Whipple's procedure. Br J Surg. 1992;79:182.
2. Heslin MJ, Harrison LE, Brooks AD, et al. Is intra-abdominal drainage necessary after pancreaticoduodenectomy? J Gastrointest Surg. 1998;2: 373-378.
3. Conlon KC, Labow D, Leung D, et al. Prospective randomized clinical trial of the value of intraperitoneal drainage after pancreatic resection. Ann Surg. 2001;234:487-493. discussion 493-4.
4. Fisher WE, Hodges SE, Silberfein EJ, et al. Pancreatic resection without routine intraperitoneal drainage. HPB (Oxford). 2011;13:503-510.
5. van der Wilt AA, Coolsen MM, de Hingh IH, et al. To drain or not to drain: A cumulative meta-analysis of the use of routine abdominal drains after pancreatic resection. HPB (Oxford). 2013;15:337-344.
6. Mehta VV, Fisher SB,Maithel SK, et al. Is it time to abandon routine operative drain use? A single institution assessment of 709 consecutive pancreaticoduodenectomies. J Am Coll Surg. 2013;216:635-642. discussion 642-4.
7. Correa-Gallego C, Brennan MF, D'Angelica M, et al. Operative drainage following pancreatic resection: analysis of 1122 patients resected over 5 years at a single institution. Ann Surg. 2013;258:1051-1058.
8. Van Buren G 2nd, Bloomston M, Hughes SJ, et al. A randomized prospective multicenter trial of pancreaticoduodenectomy with and without routine intraperitoneal drainage. Ann Surg. 2014;259:605-612.
9. McMillan MT, Fisher WE, Van Buren G 2nd, et al. The value of drains as a fistula mitigation strategy for pancreatoduodenectomy: something for everyone? Results of a randomized prospective multi-institutional study. J Gastrointest Surg. 2015;19:21-31.
10. McMillan MT, Malleo G, Bassi C, et al. Drain management after pancreatoduodenectomy: reappraisal of a prospective randomized trial using risk stratification. J Am Coll Surg. 2015;221:798-809.
11. Witzigmann H, Diener MK, Kissenkoetter S, et al. No need for routine drainage after pancreatoduodenectomy: The dual center randomized controlled PANDRA-Trial (ISRCTN04937707). Ann Surg. 2016. In press.
12. McMillan MT, Soi S, Asbun HJ, et al. Risk-adjusted outcomes of clinically relevant pancreatic fistula following pancreatoduodenectomy: A model for performance evaluation. Ann Surg. 2015. Epub ahead of print.
13. Kawai M, Tani M, Terasawa H, et al. Early removal of prophylactic drains reduces the risk of intra-abdominal infections in patients with pancreatic head resection: prospective study for 104 consecutive patients. Ann Surg. 2006;244:1-7.
14. Bassi C, Molinari E, Malleo G, et al. Early versus late drain removal after standard pancreatic resections: results of a prospective randomized trial. Ann Surg. 2010;252:207-214.
15. Molinari E, Bassi C, Salvia R, et al. Amylase value in drains after pancreatic resection as predictive factor of postoperative pancreatic fistula: results of a prospective study in 137 patients. Ann Surg. 2007;246:281-287.
16. Giglio MC, Spalding DR, Giakoustidis A, et al. Meta-analysis of drain amylase content on postoperative day 1 as a predictor of pancreatic fistula following pancreatic resection. Br J Surg. 2016;103:328-336.
17. Callery MP, Pratt WB, Kent TS, et al. A prospectively validated clinical risk score accurately predicts pancreatic fistula after pancreatoduodenectomy. J Am Coll Surg. 2013;216:1-14.
18. McMillan MT, Vollmer CM Jr, Asbun HJ, et al. The characterization and prediction of ISGPF Grade C fistulas following pancreatoduodenectomy. J Gastrointest Surg. 2016;20:262-276.
19. Bassi C, Dervenis C, Butturini G, et al. Postoperative pancreatic fistula: an international study group (ISGPF) definition. Surgery. 2005;138:8-13.
20. Porembka MR, Hall BL, Hirbe M, et al. Quantitative weighting of postoperative complications based on the accordion severity grading system: demonstration of potential impact using the american college of surgeons national surgical quality improvement program. J Am Coll Surg. 2010;210:286-298.
21. Pocock SJ. Clinical Trials: A Practical Approach. John Wiley & Sons; 2013.
22. Hanley JA, McNeil BJ. The meaning and use of the area under a receiver operating characteristic (ROC) curve. Radiology. 1982;143:29-36.
23. Sanford DE, Woolsey CA, Hall BL, et al. Variations in definition and method of retrieval of complications influence outcomes statistics after pancreatoduodenectomy: comparison of NSQIP with non-NSQIP methods. J Am Coll Surg. 2014;219:407-415.
24. McMillan MT, Vollmer CM. Peritoneal Drain Placement at Pancreatoduodenectomy. Difficult Decisions in Hepatobiliary and Pancreatic Surgery. 2016;609-620.
25. McMillan MT, Malleo G, Bassi C, et al. Defining the practice of pancreatoduodenectomy around the world. HPB (Oxford). 2015;17:1145-1154.
26. Nissen NN, Menon VG, Puri V, et al. A simple algorithm for drain management after pancreaticoduodenectomy. Am Surg. 2012;78:1143-1146.
27. Israel JS, Rettammel RJ, Leverson GE, et al. Does postoperative drain amylase predict pancreatic fistula after pancreatectomy? J Am Coll Surg. 2014;218:978-987.
28. Lee CW, Pitt HA, Riall TS, et al. Low drain fluid amylase predicts absence of pancreatic fistula following pancreatectomy. J Gastrointest Surg. 2014;18:1902-1910.
29. Partelli S, Tamburrino D, Crippa S, et al. Evaluation of a predictive model for pancreatic fistula based on amylase value in drains after pancreatic resection. Am J Surg. 2014;208:634-639.
30. McMillan MT, Vollmer CM Jr. Predictive factors for pancreatic fistula following pancreatectomy. Langenbecks Arch Surg. 2014;399:811-824.
31. Lee SE, Ahn YJ, Jang JY, et al. Prospective randomized pilot trial comparing closed suction drainage and gravity drainage of the pancreatic duct in pancreaticojejunostomy. J Hepatobiliary Pancreat Surg. 2009;16:837-843.