A new cytotoxic clerodane diterpene from casearia graveolens twigs

Natural Product Communications

Volumn 11, Issue 1, 2016, Pages 13-15

  Meesakul, Pornphimol ^a   Ritthiwigrom, Thunwadee ^b   Cheenpracha, Sarot ^c   Sripisut, Tawanun ^a   Maneerat, Wisanu ^a   MacHan, Theeraphan ^a   Laphookhieo, Surat ^a  

^a MAE FAH LUANG UNIVERSITY   (Thailand)

^b CHIANG MAI UNIVERSITY   (Thailand)

^c UNIVERSITY OF PHAYAO   (Thailand)

Author keywords

Casearia graveolens; Clerodane diterpene; Cytotoxicity; Flacourtiaceae

Indexed keywords

CASEARIA GRAVEOLENS EXTRACT; CASEARIAGRAVEOLIN; CLERODANE; CYTOTOXIC AGENT; DITERPENE; DOXORUBICIN; PLANT EXTRACT; TAMOXIFEN; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; CLERODANE DERIVATIVE;

ARTICLE; BREAST CANCER CELL LINE; CASEARIA; CASEARIA GRAVEOLENS; CONTROLLED STUDY; DRUG IDENTIFICATION; DRUG ISOLATION; DRUG SCREENING; IC50; NONHUMAN; ORAL CANCER CELL LINE; PHYTOCHEMISTRY; PLANT STRUCTURES; CHEMICAL STRUCTURE; CHEMISTRY; HUMAN; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; CASEARIA; CELL LINE, TUMOR; DITERPENES, CLERODANE; HUMANS; MOLECULAR STRUCTURE;

EID: 84973408865     PISSN: 1934578X     EISSN: 15559475     Source Type: Journal    
DOI: 10.1177/1934578x1601100105     Document Type: Article

References (24)

1. Itokawa H, Totsuka N, Takeya K, Watanabe K, Obata E. (1988) Antitumor principles from Casearia sylvestris Sw. (Flacourtiaceae), structure elucidation of new clerodane diterpenes by 2-D NMR spectroscopy. Chemical and Pharmaceutical Bulletin, 36, 1585-1588
2. Mosaddik A, Forster PI, Booth R, Waterman PG. (2006) New clerodane and halimane diterpenes from the leaves and woody stems of Casearia grayi (Flacourtiaceae/Salicaceae). Natural Product Communications, 1, 441-448
3. Mosaddik A, Waterman PG. (2006) A sesquiterpene, clerodane diterpenes and a furanone from the roots of Casearia multinervosa (Flacourtiaceae/Salicaceae). Natural Product Communications, 1, 601-607.
4. Prakash CVS, Hoch JM, Kingston DGI. (2002) Structure and stereochemistry of new cytotoxic clerodane diterpenoids from the bark of Casearia lucida from the Madagascar rainforest. Journal of Natural Products, 65, 100-107.
5. Shen YC, Wang CH, Cheng YB, Wang LT, Guh JH, Chien CT, Khalil AT. (2004) New cytotoxic clerodane diterpenoids from the leaves and twigs of Casearia membranacea. Journal of Natural Products, 67, 316-321.
6. Shen YC, Cheng YB, Ahmed AF, Lee CL, Chen SY, Chien CT, Kuo YH, Tzeng GL. (2005) Cytotoxic clerodane diterpenoids from Casearia membranacea. Journal of Natural Products, 68, 1665-1668.
7. Morita H, Nakayama M, Kojima H, Takeya K, Itokawa H, Schenkel EP, Motidome M. (1991) Structures and cytotoxic activity relationship of casearins, new clerodane diterpenes from Casearia sylvestris Sw. Chemical and Pharmaceutical Bulletin, 39, 693-697.
8. Chang KC, Duh CY, Chen IS, Tsai IL. (2003) A cytotoxic butenolide, two new dolabellane diterpenoids, a chroman and a benzoquinol derivative formosan Casearia membranacea. Planta Medica, 69, 667-672.
9. Shen YC, Wang LT, Wang CH, Khalil AT, Guh JH. (2004) Two new cytotoxic clerodane diterpenoids from Casearia membranacea. Chemical and Pharmaceutical Bulletin, 52, 108-110.
10. Wang W, Ali Z, Li XC, Smillie TA, Guo DA, Khan IA. (2009) New clerodane diterpenoids from Casearia sylvestris. Fitoterapia, 80, 404-407.
11. Williams RB, Norris A, Miller JS, Birkinshaw C, Ratovoson F, Andriantsiferana R, Rasamison VE, Kingston DG. (2007) Cytotoxic clerodane diterpenoids and their hydrolysis products from Casearia nigrescens from the rainforest of Madagascar. Journal of Natural Products, 70, 206-209.
12. Beutler JA, McCall KL, Herbert K, Herald DL, Pettit GR, Johnson T, Shoemaker RH, Boyd MR. (2000) Novel cytotoxic diterpenes from Casearia arborea. Journal of Natural Products, 63, 657-661.
13. Kanokmedhakul S, Kanokmedhakul K, Buayairaksa M. (2007) Cytotoxic clerodane diterpenoids from fruits of Casearia grewiifolia. Journal of Natural Products, 70, 1122-1126.
14. Junior GMV, Goncales TDO, Regasini LO, Ferreira PMP, Pessoa CDO, Lotufo LVC, Torres RB, Boralle N, Bolzani VDS, Cavalheiro AJ. (2009) Cytotoxic clerodane diterpenoids from Casearia oblique. Journal of Natural Products, 72, 1847-1850.
15. Junior GMV, Dutra LA, Ferreira PMP, Moraes MOD, Lotufo LVC, Pessoa CDO, Torres RB, Boralle N, Bolzani VDS, Cavalheiro AJ. (2011) Cytotoxic clerodane diterpenes from Casearia rupestris. Journal of Natural Products, 74, 776-781.
16. Kanokmedhakul S, Kanokmedhakul K, Kanarsa T, Buayairaksa M. (2005) New bioactive clerodane diterpenoids from the bark of Casearia grewiifolia. Journal of Natural Products, 68, 183-188.
17. Oberlies NH, Burgess JP, Navarro HA, Pinos RE, Fairchild CR, Peterson RW, Soejarto DD, Farnsworth NR, Kinghorn AD, Wani MC, Wall ME. (2002) Novel bioactive clerodane diterpenoids from the leaves and twigs of Casearia sylvestris. Journal of Natural Products, 65, 95-99.
18. Hunter MS, Corley DG, Carron CP, Rowold E, Kilpatrick BF, Durley RC.(1997) Four new clerodane diterpenes from the leaves of Casearia guianensis which inhibit the interaction of leukocyte function antigen 1 with intercellular adhesion molecule 1. Journal of Natural Products, 60, 894-899.
19. Itokawa H, Totsuka N, Morita H, Takeya K, Iitaka Y, Schenkel EP, Motidome M. (1990) New antitumor principles, casearins A-F, for Casearia sylvestris Sw. (Flacoutiaceae). Chemical and Pharmaceutical Bulletin, 38, 3384-3388.
20. Mosaddik MA, Forster PI, Booth R., Waterman PG. (2007) Clerodane diterpenes from the stems of Casearia grewiifolia var. gelonioides (Flacourtiaceae/Salicaceae sensu lato). Biochemical Systematics and Ecology, 35, 631-633.
21. Ruppelt BM, Pereira EF, Goncalves LC, Pereira NA. (1991) Pharmacological screening of plants recommended by folk medicine as anti-snake venom?I. Analgesic and anti-inflammatory activities. Memórias do Instituto Oswaldo Cruz, 86, 203-205.
22. Whitson EL, Thomas CL, Henrich CJ, Sayers TJ, Sayers JB, McKee TC. (2010) Clerodane diterpenes from Casearia arguta that act as synergistic TRAIL sensitizers. Journal of Natural Products, 73, 2013-2018.
23. Gibbons S, Gray AI, Waterman PG. (1996) Clerodane diterpenes from the bark of Casearia tremula. Phytochemistry, 44, 565-570.
24. Brien J, Wilson I, Orton T, Pognan F. (2000) Investigation of the alamar blue (resazurin) fluorescent dye for the assessment of mammalian cell cytotoxicity. European Journal of Biochemistry, 267, 5421-5426.