Increased epicardial fat thickness correlates with aortic stiffness and N-terminal pro-brain natriuretic peptide levels in acute ischemic stroke patients

Texas Heart Institute Journal

Volumn 43, Issue 3, 2016, Pages 220-226

  Altun, Ibrahim ^a   Unal, Yasemin ^a   Basaran, Ozcan ^a   Akin, Fatih ^a   Emir, Gulserkaradaban ^a   Kutlu, Gulnihal ^a   Biteker, Murat ^a  

^a MUGLA SITKI KOCMAN UNIVERSITY   (Turkey)

Author keywords

Adipose tissue pathology ultrasonography; Brain ischemia physiopathology; Brain blood; Cerebral infarction physiopathology; Echocardiography; Natriuretic peptide; Pericardium ultrasonography; Predictive value of tests; Prospective studies; Risk factors; Vascular stiffness physiology

Indexed keywords

ALBUMIN; AMINO TERMINAL PRO BRAIN NATRIURETIC PEPTIDE; HEMOGLOBIN; BRAIN NATRIURETIC PEPTIDE; PEPTIDE FRAGMENT; PRO-BRAIN NATRIURETIC PEPTIDE (1-76);

AGED; AORTIC DISTENSIBILITY; AORTIC STRAIN; ARTERIAL STIFFNESS; ARTICLE; BRAIN ISCHEMIA; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; DISEASE SEVERITY; EPICARDIAL FAT THICKNESS; ERYTHROCYTE SEDIMENTATION RATE; FEMALE; HEART LEFT VENTRICLE EJECTION FRACTION; HUMAN; LEUKOCYTE COUNT; MAJOR CLINICAL STUDY; MALE; MEDICAL PARAMETERS; NATIONAL INSTITUTES OF HEALTH STROKE SCALE; PROGNOSIS; RISK FACTOR; SENSITIVITY AND SPECIFICITY; THROMBOCYTE VOLUME; TRANSTHORACIC ECHOCARDIOGRAPHY; WAIST CIRCUMFERENCE; WAIST TO HEIGHT RATIO; ACUTE DISEASE; ADIPOSE TISSUE; BLOOD; DIAGNOSTIC IMAGING; ECHOCARDIOGRAPHY; FOLLOW UP; PATHOPHYSIOLOGY; PERICARDIUM; PHYSIOLOGY; PREDICTIVE VALUE; RETROSPECTIVE STUDY; THORACIC AORTA; TIME FACTOR; X-RAY COMPUTED TOMOGRAPHY;

ACUTE DISEASE; ADIPOSE TISSUE; AGED; AORTA, THORACIC; BRAIN ISCHEMIA; ECHOCARDIOGRAPHY; FEMALE; FOLLOW-UP STUDIES; HUMANS; MALE; NATRIURETIC PEPTIDE, BRAIN; PEPTIDE FRAGMENTS; PERICARDIUM; PREDICTIVE VALUE OF TESTS; RETROSPECTIVE STUDIES; RISK FACTORS; TIME FACTORS; TOMOGRAPHY, X-RAY COMPUTED; VASCULAR STIFFNESS;

EID: 84973370233     PISSN: 07302347     EISSN: 15266702     Source Type: Journal    
DOI: 10.14503/THIJ-15-5428     Document Type: Article

References (28)

1. Towfighi A, Saver JL. Stroke declines from third to fourth leading cause of death in the United States: historical perspective and challenges ahead. Stroke 2011;42(8):2351-5
2. Roger VL, Go AS, Lloyd-Jones DM, Benjamin EJ, Berry JD, Borden WB, et al. Heart disease and stroke statistics--2012 update: a report from the American Heart Association [published erratum appears in Circulation 2012;125(22):e1002]. Circulation 2012;125(1):e2-e220
3. Biteker M, Ozden T, Dayan A, Tekkesin AI, Misirli CH. Aortic stiffness and plasma brain natriuretic peptide predicts mortality in acute ischemic stroke. Int J Stroke 2015;10(5):679-85
4. Kim J, Cha MJ, Lee DH, Lee HS, Nam CM, Nam HS, et al. The association between cerebral atherosclerosis and arterial stiffness in acute ischemic stroke. Atherosclerosis 2011;219(2): 887-91
5. Bertaso AG, Bertol D, Duncan BB, Foppa M. Epicardial fat: definition, measurements and systematic review of main outcomes [in Portuguese]. Arq Bras Cardiol 2013;101(1):e18-28
6. Ouwens DM, Sell H, Greulich S, Eckel J. The role of epicardial and perivascular adipose tissue in the pathophysiology of cardiovascular disease. J Cell Mol Med 2010;14(9):2223-34
7. Akil E, Akil MA, Varol S, Ozdemir HH, Yucel Y, Arslan D, et al. Echocardiographic epicardial fat thickness and neutrophil to lymphocyte ratio are novel inflammatory predictors of cerebral ischemic stroke. J Stroke Cerebrovasc Dis 2014;23(9): 2328-34
8. Hatano S. Experience from a multicentre stroke register: a preliminary report. Bull World Health Organ 1976;54(5):541-53
9. Brott T, Marler JR, Olinger CP, Adams HP Jr, Tomsick T, Barsan WG, et al. Measurements of acute cerebral infarction: lesion size by computed tomography. Stroke 1989;20(7):871-5
10. Lee LJ, Kidwell CS, Alger J, Starkman S, Saver JL. Impact on stroke subtype diagnosis of early diffusion-weighted magnetic resonance imaging and magnetic resonance angiography. Stroke 2000;31(5):1081-9
11. Sahn DJ, DeMaria A, Kisslo J, Weyman A. Recommendations regarding quantitation in M-mode echocardiography: results of a survey of echocardiographic measurements. Circulation 1978;58(6):1072-83
12. Stefanadis C, Stratos C, Boudoulas H, Kourouklis C, Toutouzas P. Distensibility of the ascending aorta: comparison of invasive and non-invasive techniques in healthy men and in men with coronary artery disease. Eur Heart J 1990;11(11):990-6
13. Lacombe F, Dart A, Dewar E, Jennings G, Cameron J, Laufer E. Arterial elastic properties in man: a comparison of echo- Doppler indices of aortic stiffness. Eur Heart J 1992;13(8): 1040-5
14. Iacobellis G, Willens HJ. Echocardiographic epicardial fat: a review of research and clinical applications. J Am Soc Echocardiogr 2009;22(12):1311-9
15. Iacobellis G, Lonn E, Lamy A, Singh N, Sharma AM. Epicardial fat thickness and coronary artery disease correlate independently of obesity. Int J Cardiol 2011;146(3):452-4
16. Iacobellis G, Bianco AC. Epicardial adipose tissue: emerging physiological, pathophysiological and clinical features. Trends Endocrinol Metab 2011;22(11):450-7
17. Nelson MR, Mookadam F, Thota V, Emani U, Al Harthi M, Lester SJ, et al. Epicardial fat: an additional measurement for subclinical atherosclerosis and cardiovascular risk stratification? J Am Soc Echocardiogr 2011;24(3):339-45
18. Kaya H, Ertas F, Oylumlu M, Bilik MZ, Yildiz A, Yuksel M, et al. Relation of epicardial fat thickness and brachial flowmediated vasodilation with coronary artery disease. J Cardiol 2013;62(6):343-7
19. Liang KW, Tsai IC, Lee WJ, Lin SY, Lee WL, Lee IT, et al. Correlation between reduction of superior interventricular groove epicardial fat thickness and improvement of insulin resistance after weight loss in obese men. Diabetol Metab Syndr 2014;6(1):115
20. Mazurek T, Zhang L, Zalewski A, Mannion JD, Diehl JT, Arafat H, et al. Human epicardial adipose tissue is a source of inflammatory mediators. Circulation 2003;108(20):2460-6
21. Kim BJ, Kim BS, Kang JH. Echocardiographic epicardial fat thickness is associated with arterial stiffness. Int J Cardiol 2013;167(5):2234-8
22. Cabrera-Rego JO, Iacobellis G, Castillo-Herrera JA, Valiente-Mustelier J, Gandarilla-Sarmientos JC, Marin-Julia SM, Navarrete-Cabrera J. Epicardial fat thickness correlates with carotid intima-media thickness, arterial stiffness, and cardiac geometry in children and adolescents. Pediatr Cardiol 2014; 35(3):450-6
23. Altun I, Akin F, Biteker M. The role of epicardial fat thickness and neutrophil-to-lymphocyte ratio are needed to be studied in real-world stroke patients. J Stroke Cerebrovasc Dis 2015; 24(5):1100
24. Llombart V, Antolin-Fontes A, Bustamante A, Giralt D, Rost NS, Furie K, et al. B-type natriuretic peptides help in cardioembolic stroke diagnosis: pooled data meta-analysis. Stroke 2015;46(5):1187-95
25. Laurent S, Katsahian S, Fassot C, Tropeano AI, Gautier I, Laloux B, Boutouyrie P. Aortic stiffness is an independent predictor of fatal stroke in essential hypertension. Stroke 2003;34 (5):1203-6
26. Mattace-Raso FU, van der Cammen TJ, Hofman A, van Popele NM, Bos ML, Schalekamp MA, et al. Arterial stiffness and risk of coronary heart disease and stroke: the Rotterdam Study. Circulation 2006;113(5):657-63
27. Dutour A, Achard V, Sell H, Naour N, Collart F, Gaborit B, et al. Secretory type II phospholipase A2 is produced and secreted by epicardial adipose tissue and overexpressed in patients with coronary artery disease. J Clin Endocrinol Metab 2010;95(2):963-7
28. Dogan M, Turak O, Akyel A, Grbovic E, Mendi MA, Oksuz F, et al. Increased epicardial adipose tissue thickness is linked to aortic stiffness in patients with primary hypertension. Blood Press 2014;23(4):222-7.