Metabolic engineering of Corynebacterium glutamicum for methionine production by removing feedback inhibition and increasing NADPH level

Antonie van Leeuwenhoek, International Journal of General and Molecular Microbiology

Volumn 109, Issue 9, 2016, Pages 1185-1197

  Li, Ying ^a   Cong, Hua ^a   Liu, Bingnan ^b   Song, Jinzhu ^a   Sun, Xueying ^a   Zhang, Junzheng ^a   Yang, Qian ^a  

^a HARBIN INSTITUTE OF TECHNOLOGY   (China)

^b DALIAN POLYTECHNIC UNIVERSITY   (China)

Author keywords

Corynebacterium glutamicum; Feedback inhibition; Fermentation; Metabolic flux; Methionine biosynthesis

Indexed keywords

GLUCOSE 6 PHOSPHATE DEHYDROGENASE; METHIONINE; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; PENTOSE PHOSPHATE; BACTERIAL PROTEIN; PHOSPHOGLUCONATE DEHYDROGENASE;

ARTICLE; BACTERIAL GENE; BIOACCUMULATION; CONTROLLED STUDY; CORYNEBACTERIUM GLUTAMICUM; DAPA GENE; DOWN REGULATION; FED BATCH FERMENTATION; GENE DELETION; GENETIC MANIPULATION; INTRACELLULAR MEMBRANE; LYSC GENE; MUTAGENESIS; NEGATIVE FEEDBACK; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN ENGINEERING; PROTEIN SYNTHESIS; PROTEIN TRANSPORT; PYC GENE; START CODON; THRB GENE; BIOSYNTHESIS; ENZYMOLOGY; FERMENTATION; GENETICS; METABOLIC ENGINEERING; METABOLISM; PROCEDURES;

BACTERIAL PROTEINS; CORYNEBACTERIUM GLUTAMICUM; FERMENTATION; GLUCOSEPHOSPHATE DEHYDROGENASE; METABOLIC ENGINEERING; METABOLIC NETWORKS AND PATHWAYS; METHIONINE; MUTAGENESIS; NADP; PHOSPHOGLUCONATE DEHYDROGENASE;

EID: 84973098166     PISSN: 00036072     EISSN: 15729699     Source Type: Journal    
DOI: 10.1007/s10482-016-0719-0     Document Type: Article

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