Asymptomatic subjects with airway obstruction have significant impairment at exercise

Thorax

Volumn 71, Issue 9, 2016, Pages 804-811

  Soumagne, Thibaud ^a,b   Laveneziana, Pierantonio ^c,d   Veil Picard, Matthieu ^a,b   Guillien, Alicia ^a,e   Claudé, Frédéric ^a,b   Puyraveau, Marc ^f   Annesi Maesano, Isabella ^c   Roche, Nicolas ^g   Dalphin, Jean Charles ^b,h   Degano, Bruno ^a,e  

^a Service de Physiologie Explorations Fonctionnelles   (France)

^b Service de Pneumologie   (France)

^c INSERM   (France)

^d PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^e Bâtiment Socrate   (France)

^f UNIVERSITY HOSPITAL OF BESANÇON   (France)

^g Institut Cochin   (France)

^h UNIVERSITÉ DE FRANCHE COMTÉ   (France)

Author keywords

COPD Mechanisms; Exercise; Lung Physiology

Indexed keywords

ADULT; AGE DISTRIBUTION; AIRWAY OBSTRUCTION; ARTICLE; ASYMPTOMATIC DISEASE; BODY MASS; BORG SCALE; CARDIOPULMONARY EXERCISE TEST; CHRONIC OBSTRUCTIVE LUNG DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; DYSPNEA; EXERCISE TOLERANCE; FEMALE; FOLLOW UP; FORCED EXPIRATORY VOLUME; FORCED VITAL CAPACITY; HEALTH STATUS; HUMAN; HYPERINFLATION; LUNG FUNCTION TEST; MALE; OXYGEN CONSUMPTION; PRIORITY JOURNAL; RESPIRATORY TRACT DISEASE ASSESSMENT; SEX DIFFERENCE; SMOKING; SPIROMETRY; TIDAL VOLUME; AGED; CASE CONTROL STUDY; COMPLICATION; EXERCISE TEST; INHALATION TEST; MASS SCREENING; MIDDLE AGED; PATHOPHYSIOLOGY; PHYSIOLOGY; PROCEDURES; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE;

ADULT; AGED; BRONCHIAL PROVOCATION TESTS; CASE-CONTROL STUDIES; DYSPNEA; EXERCISE TEST; EXERCISE TOLERANCE; FEMALE; FORCED EXPIRATORY VOLUME; HUMANS; MALE; MASS SCREENING; MIDDLE AGED; OXYGEN CONSUMPTION; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; SPIROMETRY; TIDAL VOLUME;

EID: 84971505729     PISSN: 00406376     EISSN: 14683296     Source Type: Journal    
DOI: 10.1136/thoraxjnl-2015-207953     Document Type: Article

References (41)

1. Vestbo J, Hurd SS, Agustí AG, et al. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary. Am J Respir Crit Care Med 2013;187:347-65.
2. Halbert RJ, Natoli JL, Gano A, et al. Global burden of COPD: systematic review and meta-analysis. Eur Respir J 2006;28:523-32.
3. Soriano JB, Zielinski J, Price D. Screening for and early detection of chronic obstructive pulmonary disease. Lancet 2009;374:721-32.
4. Ofir D, Laveneziana P, Webb KA, et al. Mechanisms of dyspnea during cycle exercise in symptomatic patients with GOLD stage I chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2008;177:622-9.
5. Guenette JA, Chin RC, Cheng S, et al. Mechanisms of exercise intolerance in Global Initiative for Chronic Obstructive Lung Disease grade 1 COPD. Eur Respir J 2014;44:1177-87.
6. Díaz AA, Morales A, Díaz JC, et al. CT and physiologic determinants of dyspnea and exercise capacity during the six-minute walk test in mild COPD. Respir Med 2013;107:570-9.
7. Elbehairy AF, Webb KA, Neder JA, et al. Should mild COPD be treated? Evidence for early pharmacological intervention. Drugs 2013;73:1991-2001.
8. van den Boom G, van Schayck CP, van Möllen MP, et al. Active detection of chronic obstructive pulmonary disease and asthma in the general population. Results and economic consequences of the DIMCA program. Am J Respir Crit Care Med 1998;158:1730-8.
9. Buffels J, Degryse J, Heyrman J, et al. Office spirometry significantly improves early detection of COPD in general practice: the DIDASCO Study. Chest 2004;125:1394-9.
10. Bednarek M, Maciejewski J, Wozniak M, et al. Prevalence, severity, and underdiagnosis of COPD in primary care setting. Thorax 2008;63:402-7.
11. Zieliñski J, Bednarek M. Early detection of COPD in a high-risk population using spirometric screening. Chest 2001;119:731-6.
12. Bridevaux PO, Gerbase MW, Probst-Hensch NM, et al. Long-term decline in lung function, utilisation of care and quality of life in modified GOLD stage 1 COPD. Thorax 2008;63:768-74.
13. Bertens LC, Reitsma JB, van Mourik Y, et al. COPD detected with screening: impact on patient management and prognosis. Eur Respir J 2014;44:1571-8.
14. de Marco R, Accordini S, Antò JM, et al. Long-term outcomes in mild/moderate chronic obstructive pulmonary disease in the European community respiratory health survey. Am J Respir Crit Care Med 2009;180:956-63.
15. Mannino DM, Sonia Buist A, Vollmer WM. Chronic obstructive pulmonary disease in the older adult: what defines abnormal lung function? Thorax 2007;62:237-41.
16. Vaz Fragoso CA, Concato J, McAvay G, et al. Defining chronic obstructive pulmonary disease in older persons. Respir Med 2009;103:1468-76.
17. Quanjer PH, Cooper B, Ruppel GL, et al. Defining airflow obstruction. Eur Respir J 2015;45:561-2.
18. Degano B, Bouhaddi M, Laplante JJ, et al. [COPD in dairy farmers: screening, characterization and constitution of a cohort. The BALISTIC study]. Rev Mal Respir 2012;29:1149-56.
19. Guillien A, Puyraveau M, Soumagne T, et al. Prevalence and risk factors for COPD in farmers: a cross-sectional controlled study. Eur Respir J 2016;47:95-103.
20. Quanjer PH, Stanojevic S, Cole TJ, et al. Multi-ethnic reference values for spirometry for the 3-95-yr age range: the global lung function 2012 equations. Eur Respir J 2012;40:1324-43.
21. Macintyre N, Crapo RO, Viegi G, et al. Standardisation of the single-breath determination of carbon monoxide uptake in the lung. Eur Respir J 2005;26:720-35.
22. Wanger J, Clausen JL, Coates A, et al. Standardisation of the measurement of lung volumes. Eur Respir J 2005;26:511-22.
23. Palange P, Ward SA, Carlsen KH, et al. Recommendations on the use of exercise testing in clinical practice. Eur Respir J 2007;29:185-209.
24. Jones NL, Makrides L, Hitchcock C, et al. Normal standards for an incremental progressive cycle ergometer test. Am Rev Respir Dis 1985;131:700-8.
25. Borg GA. Psychophysical bases of perceived exertion. Med Sci Sports Exerc 1982;14:377-81.
26. O'Donnell DE, Revill SM, Webb KA. Dynamic hyperinflation and exercise intolerance in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2001;164:770-7.
27. Laveneziana P, Webb KA, Ora J, et al. Evolution of dyspnea during exercise in chronic obstructive pulmonary disease: impact of critical volume constraints. Am J Respir Crit Care Med 2011;184:1367-73.
28. Hey EN, Lloyd BB, Cunningham DJ, et al. Effects of various respiratory stimuli on the depth and frequency of breathing in man. Respir Physiol 1966;1:193-205.
29. Elbehairy AF, Raghavan N, Cheng S, et al. Physiologic characterization of the chronic bronchitis phenotype in GOLD grade IB COPD. Chest 2015;147: 1235-45.
30. Lamprecht B, Soriano JB, Studnicka M, et al. Determinants of underdiagnosis of COPD in national and international surveys. Chest 2015;148:971-85.
31. Lyngsø AM, Gottlieb V, Backer V, et al. Early detection of COPD in primary care: the Copenhagen COPD screening project. COPD 2013;10:208-15.
32. Zachariades AG, Zachariadou T, Adamide T, et al. Prevalence of chronic obstructive pulmonary disease in Cyprus: a population-based study. COPD 2012;9:259-67.
33. Roche N, Dalmay F, Perez T, et al. Impact of chronic airflow obstruction in a working population. Eur Respir J 2008;31:1227-33.
34. Barjaktarevic I, Springmeyer S, Gonzalez X, et al. Diffusing capacity for carbon monoxide correlates best with tissue volume from quantitative CT scanning analysis. Chest 2015;147:1485-93.
35. Neder JA, Arbex FF, Alencar MC, et al. Exercise ventilatory inefficiency in mild to end-stage COPD. Eur Respir J 2015;45:377-87.
36. Leith DE, Brown R. Human lung volumes and the mechanisms that set them. Eur Respir J 1999;13:468-72.
37. Gagnon P, Bussières JS, Ribeiro F, et al. Influences of spinal anesthesia on exercise tolerance in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2012;186:606-15.
38. Parshall MB, Schwartzstein RM, Adams L, et al. An official American Thoracic Society statement: update on the mechanisms, assessment, and management of dyspnea. Am J Respir Crit Care Med 2012;185:435-52.
39. Tavazzi L, Swedberg K, Komajda M, et al. Clinical profiles and outcomes in patients with chronic heart failure and chronic obstructive pulmonary disease: an efficacy and safety analysis of SHIFT study. Int J Cardiol 2013;170:182-8.
40. Chiari S, Torregiani C, Boni E, et al. Dynamic pulmonary hyperinflation occurs without expiratory flow limitation in chronic heart failure during exercise. Respir Physiol Neurobiol 2013;189:34-41.
41. O'Donnell DE, Laveneziana P, Ora J, et al. Evaluation of acute bronchodilator reversibility in patients with symptoms of GOLD stage I COPD. Thorax 2009;64:216-23.