Effects of user puff topography, device voltage, and liquid nicotine concentration on electronic cigarette nicotine yield: Measurements and model predictions

Nicotine and Tobacco Research

Volumn 17, Issue 2, 2015, Pages 150-157

  Talih, Soha ^a,b   Balhas, Zainab ^a,b   Eissenberg, Thomas ^b   Salman, Rola ^a   Karaoghlanian, Nareg ^a   Hellani, Ahmad El ^a,b   Baalbaki, Rima ^a,b   Saliba, Najat ^a,b   Shihadeh, Alan ^a,b  

^a AMERICAN UNIVERSITY OF BEIRUT   (Lebanon)

^b VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ELECTRONIC CIGARETTE; NICOTINE;

AEROSOL; ARTICLE; BLOOD LEVEL; CHEMICAL ANALYSIS; DEVICES; ELECTRIC CURRENT; MATHEMATICAL MODEL; MEASUREMENT; PARTICULATE MATTER; PRIORITY JOURNAL; SAMPLING; SIMULATION; TOPOGRAPHY; USER PUFF TOPOGRAPHY; BEHAVIOR; BIOLOGICAL MODEL; ELECTRONIC CIGARETTE; EQUIPMENT DESIGN; HUMAN; PACKAGING; PSYCHOLOGY; SMOKING;

BEHAVIOR; ELECTRONIC CIGARETTES; EQUIPMENT DESIGN; HUMANS; MODELS, BIOLOGICAL; NICOTINE; PRODUCT LABELING; SMOKING;

EID: 84922465390     PISSN: 14622203     EISSN: 1469994X     Source Type: Journal    
DOI: 10.1093/ntr/ntu174     Document Type: Article

References (39)

1. Ayers JW, Ribisl KM, Brownstein JS. Tracking the rise in popularity of electronic nicotine delivery systems (electronic cigarettes) using search query surveillance. Am J Prev Med. 2011;40: 448-453.
2. Adkison SE, O'Connor RJ, Bansal-Travers M, et al. Electronic nicotine delivery systems: international tobacco control four-country survey. Am J Prev Med. 2013;44: 207-215.
3. CDC. About one in five US adult cigarette smokers have tried an electronic cigarette. http://www.cdc.gov/media/releases/2013/p0228_electronic_cigarettes.html. Accessed May 14, 2014.
4. Hinds W. Aerosol Technology: Properties, Behavior, and Measurement of Airborne Particles. 2nd ed. Hoboken, NJ: Wiley-Interscience; 1999.
5. Noel JK, Rees VW, Connolly GN. Electronic cigarettes: a new 'tobacco' industry? Tob Control. 2011;20: 81.
6. Farsalinos KE, Romagna G, Tsiapras D, Kyrzopoulos S, Spyrou A, Voudris V. Impact of flavour variability on electronic cigarette use experience: an internet survey. Int J Environ Res Public Health. 2013;10: 7272-7282.
7. Grana RA, Ling PM. "Smoking revolution": a content analysis of electronic cigarette retail websites. Am J Prev Med. 2014;46: 395-403.
8. Henningfield JE, Zaatari GS. Electronic nicotine delivery systems: emerging science foundation for policy. Tob Control. 2010;19: 89-90.
9. Dawkins L, Corcoran O. Acute electronic cigarette use: nicotine delivery and subjective effects in regular users. Psychopharmacology (Berl). 2014;231: 401-407.
10. Vansickel AR, Eissenberg T. Electronic cigarettes: effective nicotine delivery after acute administration. Nicotine Tob Res. 2013;15: 267-270.
11. USDHHS, ed. The health consequences of smoking: Nicotine addiction: a report of the Surgeon General ((CDC) 88-8406 ed.). Center for Health Promotion and Education. Office on Smoking and Health: USDHHS. http://profiles.nlm.nih.gov/NN/B/B/Z/D/. Accessed May 15, 2014.
12. Goniewicz ML, Knysak J, Gawron M, et al. Levels of selected carcinogens and toxicants in vapour from electronic cigarettes. Tob Control. 2013;23: 133-139.
13. Westenberger BJ. Evaluation of e-cigarettes - Department of Health and Human Services, Food and Drug Administration, Center for Drug Evaluation and Research, Division of Pharmaceutical Analysis. http://www.fda.gov/downloads/drugs/scienceresearch/ucm173250.pdf. Accessed May 15, 2014.
14. Grana RA, Ling PM, Benowitz N, Glantz S. Electronic cigarettes. Circulation. 2014;129:e490-e492.
15. Bullen C, McRobbie H, Thornley S, Glover M, Lin R, Laugesen M. Effect of an electronic nicotine delivery device (e cigarette) on desire to smoke and withdrawal, user preferences and nicotine delivery: randomised cross-over trial. Tob Control. 2010;19: 98-103.
16. Eissenberg T. Electronic nicotine delivery devices: ineffective nicotine delivery and craving suppression after acute administration. Tob Control. 2010;19: 87-88.
17. Vansickel AR, Cobb CO, Weaver MF, Eissenberg TE. A clinical laboratory model for evaluating the acute effects of electronic "cigarettes": nicotine delivery profile and cardiovascular and subjective effects. Cancer Epidemiol Biomarkers Prev. 2010;19: 1945-1953.
18. Djordjevic MV, Stellman SD, Zang E. Doses of nicotine and lung carcinogens delivered to cigarette smokers. J Natl Cancer Inst. 2000;92: 106-111.
19. Katurji M, Daher N, Sheheitli H, Saleh R, Shihadeh A. Direct measurement of toxicants inhaled by water pipe users in the natural environment using a real-time in situ sampling technique. Inhal Toxicol. 2010;22: 1101-1109.
20. Maziak W, Rastam S, Shihadeh AL, et al. Nicotine exposure in daily waterpipe smokers and its relation to puff topography. Addict Behav. 2011;36: 397-399.
21. Shihadeh A. Investigation of mainstream smoke aerosol of the argileh water pipe. Food Chem Toxicol. 2003;41: 143-152.
22. Shihadeh A, Saleh R. Polycyclic aromatic hydrocarbons, carbon monoxide, "tar", and nicotine in the mainstream smoke aerosol of the narghile water pipe. Food Chem Toxicol. 2005;43: 655-661.
23. Shihadeh A, Azar S. A closed-loop control "playback" smoking machine for generating mainstream smoke aerosols. J Aerosol Med. 2006;19: 137-147.
24. Zacny JP, Stitzer ML. Monograph 7: the FTC cigarette test method for determining tar, nicotine, and carbon monoxide yields of US cigarettes, National Cancer Institute. http://cancercontrol.cancer.gov/Brp/tcrb/monographs/7/index.html. Accessed May 15, 2014.
25. Shihadeh AL, Eissenberg TE. Significance of smoking machine toxicant yields to blood-level exposure in water pipe tobacco smokers. Cancer Epidemiol Biomarkers Prev. 2011;20: 2457-2460.
26. Farsalinos KE, Romagna G, Tsiapras D, Kyrzopoulos S, Voudris V. Evaluation of electronic cigarette use (vaping) topography and estimation of liquid consumption: implications for research protocol standards definition and for public health authorities' regulation. Int J Environ Res Public Health. 2013;10: 2500-2514.
27. Hua M, Yip H, Talbot P. Mining data on usage of electronic nicotine delivery systems (ENDS) from YouTube videos. Tob Control. 2013;22: 103-106.
28. Eissenberg T, Adams C, Riggins EC III, Likness M. Smokers' sex and the effects of tobacco cigarettes: subject-rated and physiological measures. Nicotine Tob Res. 1999;1: 317-324.
29. Kleykamp BA, Jennings JM, Sams C, Weaver MF, Eissenberg T. The influence of transdermal nicotine on tobacco/nicotine abstinence and the effects of a concurrently administered cigarette in women and men. Exp Clin Psychopharmacol. 2008;16: 99-112.
30. Spindle T, Breland A, Shihadeh AL, Eissenberg, T. Examination of electronic cigarette user puff topography: the effect of a mouthpiece-based topography measurement device on plasma nicotine and subjective effects. Nicotine Tob Res. 2014; under review.
31. Kosmider L, Sobczak A, Fik M, et al. Carbonyl compounds in electronic cigarette vapors-effects of nicotine solvent and battery output voltage. Nicotine Tob Res. 2014;16: 1319-1326.
32. Goniewicz ML, Kuma T, Gawron M, Knysak J, Kosmider L. Nicotine levels in electronic cigarettes. Nicotine Tob Res. 2013;15: 158-166.
33. Trehy ML, Ye W, Hadwiger ME, et al. Analysis of electronic cigarette cartridges, refill solutions, and smoke for nicotine and nicotine related impurities. J Liq Chromatogr R T. 2011;34: 1442-1458.
34. Fuoco FC, Buonanno G, Stabile L, Vigo P. Influential parameters on particle concentration and size distribution in the mainstream of e-cigarettes. Environ Pollut. 2014;184: 523-529.
35. McQueen A, Tower S, Sumner W. Interviews with "vapers": implications for future research with electronic cigarettes. Nicotine Tob Res. 2011;13: 860-867.
36. Nides MA, Leischow SJ, Bhatter M, Simmons M. Nicotine blood levels and short-term smoking reduction with an electronic nicotine delivery system. Am J Health Behav. 2014;38: 265-274.
37. Kosmider L, Sobczak A, Knysak J, Goniewicz M. Effect of solvent and battery output voltage on nicotine levels released from electronic cigarette. Presented at: SRNT 20th Annual Meeting; February 2014; Seattle, WA.
38. Goniewicz ML, Hajek P, McRobbie H. Nicotine content of electronic cigarettes, its release in vapour and its consistency across batches: regulatory implications. Addiction. 2014;109: 500-507.
39. Farsalinos KE, Spyrou A, Tsimopoulou K, Stefopoulos C, Romagna G, Voudris V. Nicotine absorption from electronic cigarette use: comparison between first and new-generation devices. Sci Rep. 2014;4: 4133.