Synthesis and antimicrobial activity against Pseudomonas aeruginosa of macrocyclic β-hairpin peptidomimetic antibiotics containing N-methylated amino acids

Bioorganic and Medicinal Chemistry

Volumn 24, Issue 24, 2016, Pages 6332-6339

  Vetterli, Stefan U ^a   Moehle, Kerstin ^a   Robinson, John A ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

Antibiotic; Gram negative bacteria; Lipopolysaccharide transport; LptD; NMR structure; Peptide

Indexed keywords

AMINO ACID DERIVATIVE; MACROLIDE; PEPTIDOMIMETIC AGENT; AMINO ACID; ANTIINFECTIVE AGENT; MACROCYCLIC COMPOUND; PEPTIDE;

ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERIAL STRAIN; CARBON NUCLEAR MAGNETIC RESONANCE; CONTROLLED STUDY; DRUG STRUCTURE; DRUG SYNTHESIS; METHYLATION; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; PSEUDOMONAS AERUGINOSA; CHEMISTRY; DRUG EFFECTS; METABOLISM; MICROBIAL SENSITIVITY TEST; SYNTHESIS;

AMINO ACIDS; ANTI-BACTERIAL AGENTS; MACROCYCLIC COMPOUNDS; METHYLATION; MICROBIAL SENSITIVITY TESTS; PEPTIDES; PEPTIDOMIMETICS; PSEUDOMONAS AERUGINOSA;

EID: 84970045821     PISSN: 09680896     EISSN: 14643391     Source Type: Journal    
DOI: 10.1016/j.bmc.2016.05.027     Document Type: Article

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