Development of third-generation cocal envelope producer cell lines for robust lentiviral gene transfer into hematopoietic stem cells and t-cells

Molecular Therapy

Volumn 24, Issue 7, 2016, Pages 1237-1246

  Humbert, Olivier ^a   Gisch, Don W ^a   Wohlfahrt, Martin E ^a   Adams, Amie B ^a   Greenberg, Phil D ^a,b,c   Schmitt, Tom M ^a   Trobridge, Grant D ^d,e   Kiem, Hans Peter ^a,b  

^a USA   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

^c UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^d WASHINGTON STATE UNIVERSITY   (United States)

^e WASHINGTON STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD34 ANTIGEN; GAG PROTEIN; GREEN FLUORESCENT PROTEIN; HISTONE DEACETYLASE INHIBITOR; HISTONE DEACETYLASE INHIBITOR NABU; LENTIVIRUS VECTOR; LOW DENSITY LIPOPROTEIN RECEPTOR; MESSENGER RNA; REV PROTEIN; SOLUBLE LOW DENSITY LIPOPROTEIN RECEPTOR; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG; VESICULAR STOMATITIS VIRUS ENVELOPE GLYCOPROTEIN; VIRUS GLYCOPROTEIN; WT1 PROTEIN; GLYCOPROTEIN G, COCAL VIRUS; MEMBRANE PROTEIN; VIRUS ENVELOPE PROTEIN; VIRUS RECEPTOR;

ADAPTATION; AMINO ACID SEQUENCE; ARTICLE; BINDING AFFINITY; CD4+ T LYMPHOCYTE; CELL CULTURE TECHNIQUE; CELL ENTRY; CELL FREE CULTURE; CELL LINE; CELL SUSPENSION; CELLULAR, SUBCELLULAR AND MOLECULAR BIOLOGICAL PHENOMENA AND FUNCTIONS; CONTROLLED STUDY; EMBRYO; HEK293 CELL LINE; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; MOLECULAR DYNAMICS; PROCESS OPTIMIZATION; PROTEIN EXPRESSION; RNA TRANSCRIPTION; SEQUENCE HOMOLOGY; T LYMPHOCYTE; THIRD GENERATION COCAL ENVELOPE PRODUCER CELL LINE; TRANSCRIPTION REGULATION; VIRAL GENE DELIVERY SYSTEM; VIRUS TITRATION; GENE EXPRESSION; GENE VECTOR; GENETIC ENGINEERING; GENETIC TRANSDUCTION; GENETICS; LENTIVIRINAE; METABOLISM; REPORTER GENE; TRANSGENE; VESICULAR STOMATITIS INDIANA VIRUS;

CELL CULTURE TECHNIQUES; GENE EXPRESSION; GENES, REPORTER; GENETIC ENGINEERING; GENETIC VECTORS; HEK293 CELLS; HEMATOPOIETIC STEM CELLS; HUMANS; LENTIVIRUS; MEMBRANE GLYCOPROTEINS; RECEPTORS, LDL; RECEPTORS, VIRUS; T-LYMPHOCYTES; TRANSDUCTION, GENETIC; TRANSGENES; VESICULAR STOMATITIS INDIANA VIRUS; VIRAL ENVELOPE PROTEINS;

EID: 84970028787     PISSN: 15250016     EISSN: 15250024     Source Type: Journal    
DOI: 10.1038/mt.2016.70     Document Type: Article

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