Primary tumor site is a useful predictor of cetuximab efficacy in the third-line or salvage treatment of KRAS wild-type (exon 2 non-mutant) metastatic colorectal cancer: A nationwide cohort study

BMC Cancer

Volumn 16, Issue 1, 2016, Pages

  Chen, Kuo Hsing ^a,b   Shao, Yu Yun ^a,b   Chen, Ho Min ^a   Lin, Yu Lin ^a,b   Lin, Zhong Zhe ^a,b   Lai, Mei Shu ^a,c,d   Cheng, Ann Lii ^a,b   Yeh, Kun Huei ^a,b  

^a NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^c Taiwan Cancer Registry   (Taiwan)

^d NATIONAL TAIWAN UNIVERSITY   (Taiwan)

Author keywords

Cetuximab; Colorectal cancer; KRAS wild type; Predictive biomarker; Primary tumor site

Indexed keywords

CETUXIMAB; ANTINEOPLASTIC AGENT; KRAS PROTEIN, HUMAN; PROTEIN P21;

ADULT; ARTICLE; CANCER SURVIVAL; CLINICAL EFFECTIVENESS; COHORT ANALYSIS; COLON CARCINOGENESIS; COLORECTAL CANCER; CONTROLLED STUDY; DISEASE ACTIVITY; DRUG EFFICACY; DRUG RESPONSE; EXON; FEMALE; HUMAN; LEFT SIDED COLORECTAL CANCER; MAJOR CLINICAL STUDY; MALE; METASTATIC COLORECTAL CANCER; MIDDLE AGED; MOLECULAR PATHOLOGY; ONCOGENE K RAS; OUTCOME ASSESSMENT; OVERALL SURVIVAL; PREDICTION; PRIMARY TUMOR; RIGHT SIDED COLORECTAL CANCER; SURVIVAL RATE; TUMOR LOCALIZATION; ADENOCARCINOMA; ADOLESCENT; AGED; CANCER GRADING; CANCER STAGING; COLORECTAL NEOPLASMS; FOLLOW UP; GENETICS; LYMPH NODE METASTASIS; MUTATION; PATHOLOGY; PROGNOSIS; SALVAGE THERAPY; SECONDARY; TAIWAN; TUMOR INVASION; TUMOR RECURRENCE; YOUNG ADULT;

ADENOCARCINOMA; ADOLESCENT; ADULT; AGED; ANTINEOPLASTIC AGENTS; CETUXIMAB; COHORT STUDIES; COLORECTAL NEOPLASMS; FOLLOW-UP STUDIES; HUMANS; LYMPHATIC METASTASIS; MALE; MIDDLE AGED; MUTATION; NEOPLASM GRADING; NEOPLASM INVASIVENESS; NEOPLASM RECURRENCE, LOCAL; NEOPLASM STAGING; PROGNOSIS; PROTO-ONCOGENE PROTEINS P21(RAS); SALVAGE THERAPY; SURVIVAL RATE; TAIWAN; YOUNG ADULT;

EID: 84970016836     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/s12885-016-2358-2     Document Type: Article

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