The role of human coronaviruses in children hospitalized for acute bronchiolitis, acute gastroenteritis, and febrile seizures: A 2-year prospective study

PLoS ONE

Volumn 11, Issue 5, 2016, Pages

  Jevšnik, Monika ^a   Steyer, Andrej ^a   Pokorn, Marko ^b   Mrvič, Tatjana ^b   Grosek, Štefan ^b   Strle, Franc ^b   Lusa, Lara ^c   Petrovec, Miroslav ^a  

^a UNIVERSITY OF LJUBLJANA   (Slovenia)

^b UNIVERSITY MEDICAL CENTRE LJUBLJANA   (Slovenia)

^c UNIVERSITY OF LJUBLJANA   (Slovenia)

Author keywords

[No Author keywords available]

Indexed keywords

ANTICONVULSIVE AGENT;

ACUTE GASTROENTERITIS; ARTICLE; BRONCHIOLITIS; CHILD; CONTROLLED STUDY; CORONAVIRIDAE; DISEASE ASSOCIATION; FEBRILE CONVULSION; FECES ANALYSIS; FEMALE; GENE AMPLIFICATION; HOSPITAL ADMISSION; HUMAN; MAJOR CLINICAL STUDY; MALE; NONHUMAN; NOSE SMEAR; NUCLEOTIDE SEQUENCE; PATHOGENESIS; PROSPECTIVE STUDY; THROAT CULTURE; VIRUS DETECTION; VIRUS LOAD; VIRUS VIRULENCE; ACUTE DISEASE; CLINICAL TRIAL; COMPLICATION; DNA SEQUENCE; FOLLOW UP; GASTROENTERITIS; HOSPITALIZED CHILD; NASOPHARYNX; PATHOLOGY; PHYSIOLOGY; SEASON; SEIZURES, FEBRILE; VIROLOGY;

ACUTE DISEASE; BRONCHIOLITIS; CHILD; CHILD, HOSPITALIZED; CORONAVIRUS; FEMALE; FOLLOW-UP STUDIES; GASTROENTERITIS; HUMANS; MALE; NASOPHARYNX; PROSPECTIVE STUDIES; SEASONS; SEIZURES, FEBRILE; SEQUENCE ANALYSIS, DNA;

EID: 84969941145     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0155555     Document Type: Article

References (50)

1. Pene F, Merlat A, Vabret A, Rozenberg F, Buzyn A, Dreyfus F, et al. Coronavirus 229E-related pneumonia in immunocompromised patients. Clin Infect Dis. 2003; 37(7):929-32. PMID: 13130404.
2. Vabret A, Mourez T, Gouarin S, Petitjean J, Freymuth F. An outbreak of coronavirus OC43 respiratory infection in Normandy, France. Clin Infect Dis. 2003; 36(8):985-9. PMID: 12684910.
3. Woo PC, Lau SK, Tsoi HW, Huang Y, Poon RW, Chu CM, et al. Clinical and molecular epidemiological features of coronavirus HKU1-associated community-acquired pneumonia. The Journal of infectious diseases. 2005; 192(11):1898-907. PMID: 16267760.
4. Kuypers J, Martin ET, Heugel J, Wright N, Morrow R, Englund JA. Clinical disease in children associated with newly described coronavirus subtypes. Pediatrics. 2007; 119(1):e70-6. PMID: 17130280.
5. Talbot HK, Crowe JE Jr, Edwards KM, Griffin MR, Zhu Y, Weinberg GA, et al. Coronavirus infection and hospitalizations for acute respiratory illness in young children. Journal of medical virology. 2009; 81(5):853-6. PMID: 19319948. doi: 10.1002/jmv.21443
6. van der Hoek L, Sure K, Ihorst G, Stang A, Pyrc K, Jebbink MF, et al. Croup is associated with the novel coronavirus NL63. PLoS medicine. 2005; 2(8):e240. PMID: 16104827.
7. Wu PS, Chang LY, Berkhout B, van der Hoek L, Lu CY, Kao CL, et al. Clinical manifestations of human coronavirus NL63 infection in children in Taiwan. European journal of pediatrics. 2008; 167(1):75-80. PMID: 17297612.
8. Han TH, Chung JY, Kim SW, Hwang ES. Human Coronavirus-NL63 infections in Korean children, 2004-2006. Journal of Clinical Virology. 2007; 38(1):27-31. PMID: 17137835.
9. Suzuki A, Okamoto M, Ohmi A, Watanabe O, Miyabayashi S, Nishimura H. Detection of human coronavirus-NL63 in children in Japan. The Pediatric infectious disease journal. 2005; 24(7):645-6. PMID: 15999010.
10. Ebihara T, Endo R, Ma X, Ishiguro N, Kikuta H. Detection of human coronavirus NL63 in young children with bronchiolitis. Journal of medical virology. 2005; 75(3):463-5. PMID: 15648061.
11. Vabret A, Mourez T, Dina J, van der Hoek L, Gouarin S, Petitjean J, et al. Human coronavirus NL63, France. Emerging infectious diseases. 2005; 11(8):1225-9. PMID: 16102311.
12. Lau SK, Woo PC, Yip CC, Tse H, Tsoi HW, Cheng VC, et al. Coronavirus HKU1 and other coronavirus infections in Hong Kong. Journa of Clinical Microbiology. 2006; 44(6):2063-71. PMID: 16757599.
13. Kuypers J, Martin ET, Heugel J, Wright N, Morrow R, Englund JA. Clinical disease in children associated with newly described coronavirus subtypes. Pediatrics. 2007; 119(1):e70-6. PMID: 17130280.
14. Bosis S, Esposito S, Niesters HG, Tremolati E, Pas S, Principi N, et al. Coronavirus HKU1 in an Italian pre-term infant with bronchiolitis. Journal of Clinical Virology. 2007; 38(3):251-3. PMID: 17320791.
15. Risku M, Lappalainen S, Rasanen S, Vesikari T. Detection of human coronaviruses in children with acute gastroenteritis. Journal of Clinical Virology. 2010; 48(1):27-30. PMID: 20233673. doi: 10.1016/j.jcv.2010.02.013
16. Esper F, Ou Z, Huang YT. Human coronaviruses are uncommon in patients with gastrointestinal illness. Journal of Clinical Virology. 2010; 48(2):131-3. PMID: 20362494. doi: 10.1016/j.jcv.2010.03.007
17. Clarke SK, Caul EO, Egglestone SI. The human enteric coronaviruses. Postgraduate medical journal. 1979; 55(640):135-42. PMID: 461276.
18. Stewart JN, Mounir S, Talbot PJ. Human coronavirus gene expression in the brains of multiple sclerosis patients. Virology. 1992; 191(1):502-5. PMID: 1413524.
19. Yeh EA, Collins A, Cohen ME, Duffner PK, Faden H. Detection of coronavirus in the central nervous system of a child with acute disseminated encephalomyelitis. Pediatrics. 2004; 113(1 Pt 1):e73-6. PMID: 14702500.
20. Jevsnik M, Steyer A, Zrim T, Pokorn M, Mrvic T, Grosek S, et al. Detection of human coronaviruses in simultaneously collected stool samples and nasopharyngeal swabs from hospitalized children with acute gastroenteritis. Virology journal. 2013; 10:46. Epub 2013/02/06. doi: 10.1186/1743-422X-10-46 PMID: 23379823; PubMed Central PMCID: PMC3610273.
21. Diallo IS, Hewitson G, Wright L, Rodwell BJ, Corney BG. Detection of equine herpesvirus type 1 using a real-time polymerase chain reaction. Journal of virological methods. 2006; 131(1):92-8. Epub 2005/09/03. doi: 10.1016/j.jviromet.2005.07.010 PMID: 16137772.
22. Mankoc S, Hostnik P, Grom J, Toplak I, Klobucar I, Kosec M, et al. Comparison of different molecular methods for assessment of equine arteritis virus (EAV) infection: a novel one-step MGB real-time RT-PCR assay, PCR-ELISA and classical RT-PCR for detection of highly diverse sequences of Slovenian EAV variants. Journal of virological methods. 2007; 146(1-2):341-54. PMID: 17854913.
23. Kuypers J, Wright N, Morrow R. Evaluation of quantitative and type-specific real-time RT-PCR assays for detection of respiratory syncytial virus in respiratory specimens from children. Journal of clinical virology. 2004; 31(2):123-9. Epub 2004/09/15. doi: 10.1016/j.jcv.2004.03.018 PMID: 15364268.
24. Kuypers J, Wright N, Ferrenberg J, Huang ML, Cent A, Corey L, et al. Comparison of real-time PCR assays with fluorescent-antibody assays for diagnosis of respiratory virus infections in children. Journal of clinical microbiology. 2006; 44(7):2382-8. Epub 2006/07/11. doi: 10.1128/JCM.00216-06 PMID: 16825353; PubMed Central PMCID: PMC1489473.
25. Daum LT, Canas LC, Arulanandam BP, Niemeyer D, Valdes JJ, Chambers JP. Real-time RT-PCR assays for type and subtype detection of influenza A and B viruses. Influenza and other respiratory viruses. 2007; 1(4):167-75. Epub 2007/07/01. doi: 10.1111/j.1750-2659.2007.00024.x PMID: 19432632.
26. Maertzdorf J, Wang CK, Brown JB, Quinto JD, Chu M, de Graaf M, et al. Real-time reverse transcriptase PCR assay for detection of human metapneumoviruses from all known genetic lineages. Journal of clinical microbiology. 2004; 42(3):981-6. Epub 2004/03/09. PMID: 15004041; PubMed Central PMCID: PMC356857.
27. Lu X, Chittaganpitch M, Olsen SJ, Mackay IM, Sloots TP, Fry AM, et al. Real-time PCR assays for detection of bocavirus in human specimens. Journal of clinical microbiology. 2006; 44(9):3231-5. PMID: 16954253.
28. De Vos N, Vankeerberghen A, Vaeyens F, Van Vaerenbergh K, Boel A, De Beenhouwer H. Simultaneous detection of human bocavirus and adenovirus by multiplex real-time PCR in a Belgian paediatric population. European journal of clinical microbiology & infectious diseases. 2009; 28(11):1305-10. Epub 2009/08/26. doi: 10.1007/s10096-009-0780-y PMID: 19705175.
29. Scheltinga SA, Templeton KE, Beersma MF, Claas EC. Diagnosis of human metapneumovirus and rhinovirus in patients with respiratory tract infections by an internally controlled multiplex real-time RNA PCR. Journal of clinical virology. 2005; 33(4):306-11. Epub 2005/07/05. doi: 10.1016/j.jcv.2004.08.021 PMID: 15994117.
30. Kageyama T, Kojima S, Shinohara M, Uchida K, Fukushi S, Hoshino FB, et al. Broadly reactive and highly sensitive assay for Norwalk-like viruses based on real-time quantitative reverse transcription-PCR. Journal of clinical microbiology. 2003; 41(4):1548-57. PMID: 12682144.
31. Svraka S, van der Veer B, Duizer E, Dekkers J, Koopmans M, Vennema H. Novel approach for detection of enteric viruses to enable syndrome surveillance of acute viral gastroenteritis. Journal of clinical microbiology. 2009; 47(6):1674-9. Epub 2009/04/03. doi: 10.1128/JCM.00307-09 PMID: 19339472; PubMed Central PMCID: PMC2691081.
32. R CoreTeam. R: A language and environment for statistical computing. R Foundation for statistical Computing Vienna, Austria 2015. Available from: http://www.R-project.org/.
33. Vabret A, Dina J, Gouarin S, Petitjean J, Corbet S, Freymuth F. Detection of the new human coronavirus HKU1: a report of 6 cases. Clinical Infectious Diseases. 2006; 42(5):634-9. PMID: 16447108.
34. Woo PC, Yuen KY, Lau SK. Epidemiology of coronavirus-associated respiratory tract infections and the role of rapid diagnostic tests: a prospective study. Hong Kong medical journal = Xianggang yi xue za zhi / Hong Kong Academy of Medicine. 2012; 18 Suppl 2:22-4. Epub 2012/02/15. PMID: 22311356.
35. Esposito S, Bosis S, Niesters HG, Tremolati E, Begliatti E, Rognoni A, et al. Impact of human coronavirus infections in otherwise healthy children who attended an emergency department. Journal of medical virology. 2006; 78(12):1609-15. PMID: 17063525.
36. Gaunt ER, Hardie A, Claas EC, Simmonds P, Templeton KE. Epidemiology and clinical presentations of the four human coronaviruses 229E, HKU1, NL63, and OC43 detected over 3 years using a novel multiplex real-time PCR method. Journal of clinical microbiology. 2010; 48(8):2940-7. PMID: 20554810. doi: 10.1128/JCM.00636-10
37. Kistler A, Avila PC, Rouskin S, Wang D, Ward T, Yagi S, et al. Pan-viral screening of respiratory tract infections in adults with and without asthma reveals unexpected human coronavirus and human rhinovirus diversity. The Journal of infectious diseases. 2007; 196(6):817-25. PMID: 17703411.
38. Kristoffersen AW, Nordbo SA, Rognlien AG, Christensen A, Dollner H. Coronavirus causes lower respiratory tract infections less frequently than RSV in hospitalized Norwegian children. The Pediatric infectious disease journal. 2011; 30(4):279-83. PMID: 21057374. doi: 10.1097/INF.0b013e3181fcb159
39. Miller EK, Gebretsadik T, Carroll KN, Dupont WD, Mohamed YA, Morin LL, et al. Viral etiologies of infant bronchiolitis, croup and upper respiratory illness during 4 consecutive years. The Pediatric infectious disease journal. 2013; 32(9):950-5. doi: 10.1097/INF.0b013e31829b7e43 PMID: 23694832; PubMed Central PMCID: PMCPMC3880140.
40. Paloniemi M, Lappalainen S, Vesikari T. Commonly circulating human coronaviruses do not have a significant role in the etiology of gastrointestinal infections in hospitalized children. J Clin Virol. 2015; 62:114-7. doi: 10.1016/j.jcv.2014.10.017 PMID: 25464968.
41. Brian DA, Baric RS. Coronavirus genome structure and replication. Current topics in microbiology and immunology. 2005; 287:1-30. PMID: 15609507.
42. Desforges M, Le Coupanec A, Stodola JK, Meessen-Pinard M, Talbot PJ. Human coronaviruses: viral and cellular factors involved in neuroinvasiveness and neuropathogenesis. Virus research. 2014; 194:145-58. doi: 10.1016/j.virusres.2014.09.011 PMID: 25281913.
43. Chiu SS, Chan KH, Chu KW, Kwan SW, Guan Y, Poon LL, et al. Human coronavirus NL63 infection and other coronavirus infections in children hospitalized with acute respiratory disease in Hong Kong, China. Clinical infectious diseases. 2005; 40(12):1721-9. PMID: 15909257.
44. Leung TF, Li CY, Lam WY, Wong GW, Cheuk E, Ip M, et al. Epidemiology and clinical presentations of human coronavirus NL63 infections in hong kong children. Journal of clinical microbiology. 2009; 47(11):3486-92. PMID: 19759228. doi: 10.1128/JCM.00832-09
45. Jevsnik M, Ursic T, Zigon N, Lusa L, Krivec U, Petrovec M. Coronavirus infections in hospitalized pediatric patients with acute respiratory tract disease. BMC Infect Dis. 2012; 12:365. PMID: 23256846. doi: 10.1186/1471-2334-12-365
46. Woo PC, Yuen KY, Lau SK. Epidemiology of coronavirus-associated respiratory tract infections and the role of rapid diagnostic tests: a prospective study. Hong Kong Medical Journal. 2012; 18 Suppl 2:22-4. PMID: 22311356.
47. Matoba Y, Abiko C, Ikeda T, Aoki Y, Suzuki Y, Yahagi K, et al. Detection of the human coronavirus 229E, HKU1, NL63, and OC43 between 2010 and 2013 in Yamagata, Japan. Japanese journal of infectious diseases. 2015; 68(2):138-41. doi: 10.7883/yoken.JJID.2014.266 PMID: 25420656.
48. Jin Y, Zhang RF, Xie ZP, Yan KL, Gao HC, Song JR, et al. Newly identified respiratory viruses associated with acute lower respiratory tract infections in children in Lanzou, China, from 2006 to 2009. Clin Microbiol Infect. 2012; 18(1):74-80. doi: 10.1111/j.1469-0691.2011.03541.x PMID: 21767329.
49. Stempel HE, Martin ET, Kuypers J, Englund JA, Zerr DM. Multiple viral respiratory pathogens in children with bronchiolitis. Acta paediatrica. 2009; 98(1):123-6. Epub 2008/09/13. doi: 10.1111/j.1651-2227.2008.01023.x PMID: 18785966; PubMed Central PMCID: PMC2605206.
50. Chen YW, Huang YC, Ho TH, Huang CG, Tsao KC, Lin TY. Viral etiology of bronchiolitis among pediatric inpatients in northern Taiwan with emphasis on newly identified respiratory viruses. Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi. 2014; 47(2):116-21. doi: 10.1016/j.jmii.2012.08.012 PMID: 23040235.