Combinatorial targeting of TSLP, IL-25, and IL-33 in type 2 cytokine-driven inflammation and fibrosis

Science Translational Medicine

Volumn 8, Issue 337, 2016, Pages

  Vannella, Kevin M ^a   Ramalingam, Thirumalai R ^a   Borthwick, Lee A ^a,b   Barron, Luke ^a   Hart, Kevin M ^a   Thompson, Robert W ^a   Kindrachuk, Kristen N ^a   Cheever, Allen W ^a,c   White, Sandra ^a   Budelsky, Alison L ^d   Comeau, Michael R ^d   Smith, Dirk E ^d   Wynn, Thomas A ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b NEWCASTLE UNIVERSITY   (United Kingdom)

^c BIOMEDICAL RESEARCH INSTITUTE   (United States)

^d AMGEN INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 25; INTERLEUKIN 25 MONOCLONAL ANTIBODY; INTERLEUKIN 33; INTERLEUKIN 33 MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY; NEUTRALIZING ANTIBODY; THYMIC STROMAL LYMPHOPOIETIN; THYMIC STROMAL LYMPHOPOIETIN MONOCLONAL ANTIBODY; UNCLASSIFIED DRUG; CYTOKINE; INTERLEUKIN 13; INTERLEUKIN 17; INTERLEUKIN 4;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOKINE RESPONSE; DRUG TARGETING; EOSINOPHIL; FEMALE; GENE INACTIVATION; HOUSE DUST ALLERGY; INNATE IMMUNITY; INTRACELLULAR SIGNALING; LIVER FIBROSIS; LUNG FIBROSIS; LUNG GRANULOMA; LYMPHOID CELL; MALE; MOUSE; MUCUS SECRETION; NONHUMAN; PNEUMONIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TARGETING; RESPIRATORY TRACT ALLERGY; SCHISTOSOMA MANSONI; SCHISTOSOMIASIS; ANIMAL; ANTAGONISTS AND INHIBITORS; BAGG ALBINO MOUSE; C57BL MOUSE; FIBROSIS; GENETICS; GRANULOMA; IMMUNOLOGY; INFLAMMATION; KNOCKOUT MOUSE; LUNG TUMOR; METABOLISM; PARASITOLOGY; PATHOGENICITY;

ANIMALS; ANTIBODIES, MONOCLONAL; CYTOKINES; FEMALE; FIBROSIS; GRANULOMA; INFLAMMATION; INTERLEUKIN-13; INTERLEUKIN-17; INTERLEUKIN-33; INTERLEUKIN-4; LUNG NEOPLASMS; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, KNOCKOUT; SCHISTOSOMA MANSONI;

EID: 84969941113     PISSN: 19466234     EISSN: 19466242     Source Type: Journal    
DOI: 10.1126/scitranslmed.aaf1938     Document Type: Article

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