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Volumn 13, Issue 2, 2016, Pages 195-199

A double-blind, randomized and placebo-controlled trial of Saffron (Crocus sativus L.) in the treatment of anxiety and depression

Author keywords

anxiety; Beck Anxiety Inventory (BAI); Beck Depression Inventory (BDI); depression; saffron

Indexed keywords

ANTIDEPRESSANT AGENT; ANXIOLYTIC AGENT; CROCUS SATIVUS EXTRACT; PLACEBO; PLANT MEDICINAL PRODUCT;

EID: 84969802845     PISSN: None     EISSN: 15533840     Source Type: Journal    
DOI: 10.1515/jcim-2015-0043     Document Type: Article
Times cited : (107)

References (22)
  • 3
    • 0030964895 scopus 로고    scopus 로고
    • Compliance during treatment with antidepressants
    • Demyttenaere K. Compliance during treatment with antidepressants. J Affect Disord 1997;43:27-39.
    • (1997) J Affect Disord , vol.43 , pp. 27-39
    • Demyttenaere, K.1
  • 4
    • 13544274008 scopus 로고    scopus 로고
    • Hydroalcoholic extract of Crocus sativus L. Versus fluoxetine in the treatment of mild to moderate depression: A double-blind, randomized pilot trial
    • Noorbala AA, Akhondzadeh S, Tamacebi-pour N, Jamshidi AH. Hydroalcoholic extract of Crocus sativus L. versus fluoxetine in the treatment of mild to moderate depression: a double-blind, randomized pilot trial. Ethnopharmacology 2005;97:281-4.
    • (2005) Ethnopharmacology , vol.97 , pp. 281-284
    • Noorbala, A.A.1    Akhondzadeh, S.2    Tamacebi-Pour, N.3    Jamshidi, A.H.4
  • 5
    • 33845685607 scopus 로고    scopus 로고
    • The evidence base of complementary and alternative therapies in depression
    • Thachil AF, Mohan R, Bhugra D. The evidence base of complementary and alternative therapies in depression. J Affect Disord 2007;97:23-35.
    • (2007) J Affect Disord , vol.97 , pp. 23-35
    • Thachil, A.F.1    Mohan, R.2    Bhugra, D.3
  • 6
    • 84870469320 scopus 로고    scopus 로고
    • American Psychiatric Association Washington DC: American Psychiatric Association
    • American Psychiatric Association. Diagnostic and statistical manual of mental disorders. Washington, DC: American Psychiatric Association, 2000.
    • (2000) Diagnostic and Statistical Manual of Mental Disorders
  • 7
    • 34547718033 scopus 로고    scopus 로고
    • Current treatment of generalized anxiety disorder
    • Antai-Otong D. Current treatment of generalized anxiety disorder. J Psychosoc Nurs Ment Health Serv 2003;41:20-9.
    • (2003) J Psychosoc Nurs Ment Health Serv , vol.41 , pp. 20-29
    • Antai-Otong, D.1
  • 8
    • 33750500316 scopus 로고    scopus 로고
    • Crocus sativus L. (petal) in the treatment of mild-to-moderate depression: A double-blind, randomized and Placebo-Controlled trial
    • Moshiri E, Basti AA, Noorbala AA, Jamshidi AH, Hesameddin Abbasi S, Akhondzadeh S. Crocus sativus L. (petal) in the treatment of mild-to-moderate depression: a double-blind, randomized and placebo-controlled trial. Phytomedicine 2006;13:607-11.
    • (2006) Phytomedicine , vol.13 , pp. 607-611
    • Moshiri, E.1    Basti, A.A.2    Noorbala, A.A.3    Jamshidi, A.H.4    Hesameddin Abbasi, S.5    Akhondzadeh, S.6
  • 9
    • 84974658484 scopus 로고    scopus 로고
    • Saffron supplements decrease serum prooxidant-antioxidant balance in patients with metabolic Syndrome: A randomized, placebo-controlled clinical trial
    • Epub ahead of print
    • Kermani T, Mousavi SH, Shemshian M, Norouzy A, Mazidi M, Moezzi A, et al. Saffron supplements decrease serum prooxidant-antioxidant balance in patients with metabolic syndrome: a randomized, placebo-controlled clinical trial. Avicenna J Phytomed 2015, Epub ahead of print.
    • (2015) Avicenna J Phytomed
    • Kermani, T.1    Mousavi, S.H.2    Shemshian, M.3    Norouzy, A.4    Mazidi, M.5    Moezzi, A.6
  • 11
    • 0029934789 scopus 로고    scopus 로고
    • An update review of saffron and its active constituents
    • Rios JL, Recio MC, Giner RM, Manez S. An update review of saffron and its active constituents. Phytother Res 1996;10:189-93.
    • (1996) Phytother Res , vol.10 , pp. 189-193
    • Rios, J.L.1    Recio, M.C.2    Giner, R.M.3    Manez, S.4
  • 12
    • 0141746538 scopus 로고    scopus 로고
    • Petal and stigma extracts of Crocus sativus L. Have antinociceptive and anti-inflammatory effects in mice
    • Hosseinzadeh H, Younesi H. Petal and stigma extracts of Crocus sativus L. have antinociceptive and anti-inflammatory effects in mice. BMC Pharmacol 2002;2:7.
    • (2002) BMC Pharmacol , vol.2 , pp. 7
    • Hosseinzadeh, H.1    Younesi, H.2
  • 13
    • 10444251371 scopus 로고    scopus 로고
    • Study of antidepressant effect of aqueous and ethanolic extracts of Crocus sativus in mice
    • Karimi G, Hosseinzadeh H, Khaleghpanah P. Study of antidepressant effect of aqueous and ethanolic extracts of Crocus sativus in mice. Iranian J Basic Med Sci 2001;4:11-15.
    • (2001) Iranian J Basic Med Sci , vol.4 , pp. 11-15
    • Karimi, G.1    Hosseinzadeh, H.2    Khaleghpanah, P.3
  • 14
    • 18444399219 scopus 로고    scopus 로고
    • Crocus sativus L. in the treatment of mild to moderate depression: A double-blind, randomized and placebo controlled trial
    • Akhondzadeh S, Tamacebi-pour N, Noorbala AA, Amini H, Fallah Pour H, Jamshidi AH, et al. Crocus sativus L. in the treatment of mild to moderate depression: a double-blind, randomized and placebo controlled trial. Phytother Res 2005;19:25-9.
    • (2005) Phytother Res , vol.19 , pp. 25-29
    • Akhondzadeh, S.1    Tamacebi-Pour, N.2    Noorbala, A.A.3    Amini, H.4    Fallah Pour, H.5    Jamshidi, A.H.6
  • 15
    • 85016856659 scopus 로고    scopus 로고
    • Ghrelin, food intake, and botanical Extracts: A Review
    • Epub ahead of print
    • Rezaie P, Mazidi M, Nematy M. Ghrelin, food intake, and botanical extracts: A Review. Avicenna J Phytomed 2015, Epub ahead of print.
    • (2015) Avicenna J Phytomed
    • Rezaie, P.1    Mazidi, M.2    Nematy, M.3
  • 16
    • 67149128716 scopus 로고    scopus 로고
    • Anxiolytic and hypnotic effect of Crocus sativus aqueous extract and its constituents, crocin and safranal, in mice
    • Hosseinzadeh H, Noraei NB. Anxiolytic and hypnotic effect of Crocus sativus aqueous extract and its constituents, crocin and safranal, in mice. Phytother Res 2009;23:768-74.
    • (2009) Phytother Res , vol.23 , pp. 768-774
    • Hosseinzadeh, H.1    Noraei, N.B.2
  • 18
    • 0029558356 scopus 로고
    • Mood disorders in the general population represent an important and worldwide public health problem
    • Judd L. Mood disorders in the general population represent an important and worldwide public health problem. Int J Clin Psychopharm 1995;10:5-10.
    • (1995) Int J Clin Psychopharm , vol.10 , pp. 5-10
    • Judd, L.1
  • 19
    • 10444231865 scopus 로고    scopus 로고
    • Comparison of Crocus sativus L. and imipramine in the treatment of mild to moderate depression: A pilot double-blind randomized trial
    • Akhondzadeh S, Fallah Pour H, Afkham K, Jamshidi AH, Khalighi-Cigarodi F. Comparison of Crocus sativus L. and imipramine in the treatment of mild to moderate depression: a pilot double-blind randomized trial. BMC Complement Altern Med 2004;4:12.
    • (2004) BMC Complement Altern Med , vol.4 , pp. 12
    • Akhondzadeh, S.1    Fallah Pour, H.2    Afkham, K.3    Jamshidi, A.H.4    Khalighi-Cigarodi, F.5
  • 20
    • 84866909578 scopus 로고    scopus 로고
    • Effects of the active constituents of Crocus Sativus L., crocins, in an animal model of obsessive-compulsive disorder
    • Georgiadou G, Tarantilis PA, Pitsikas N. Effects of the active constituents of Crocus Sativus L., crocins, in an animal model of obsessive-compulsive disorder. Neurosci Lett 2012;528:27-30.
    • (2012) Neurosci Lett , vol.528 , pp. 27-30
    • Georgiadou, G.1    Tarantilis, P.A.2    Pitsikas, N.3
  • 21
    • 77949490080 scopus 로고    scopus 로고
    • Antidepressant properties of bioactive fractions from the extract of Crocus sativus L
    • Wang Y, Han T, Zhu Y, Zheng CJ, Ming QL, Rahman K, et al. Antidepressant properties of bioactive fractions from the extract of Crocus sativus L. J Nat Med 2010;64:24-30.
    • (2010) J Nat Med , vol.64 , pp. 24-30
    • Wang, Y.1    Han, T.2    Zhu, Y.3    Zheng, C.J.4    Ming, Q.L.5    Rahman, K.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.