메뉴 건너뛰기




Volumn 65, Issue 6, 2016, Pages 1714-1723

Glucagon-like peptide 1 receptor activation attenuates platelet aggregation and thrombosis

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE DIPHOSPHATE; CYCLIC AMP; ENDOTHELIAL NITRIC OXIDE SYNTHASE; EXENDIN 4; GLUCAGON LIKE PEPTIDE 1 RECEPTOR; THROMBIN; ANTITHROMBOCYTIC AGENT; GLUCAGON LIKE PEPTIDE 1; PEPTIDE; VENOM;

EID: 84969776766     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db15-1141     Document Type: Article
Times cited : (95)

References (50)
  • 2
    • 84957440989 scopus 로고    scopus 로고
    • Platelets in hemostasis and thrombosis: Novel mechanisms of fibrinogen-independent platelet aggregation and fibronectin-mediated protein wave of hemostasis
    • 30 October [Epub ahead of print]
    • Hou Y, Carrim N, Wang Y, Gallant RC, Marshall A, Ni H. Platelets in hemostasis and thrombosis: novel mechanisms of fibrinogen-independent platelet aggregation and fibronectin-mediated protein wave of hemostasis. J Biomed Res. 30 October 2015 [Epub ahead of print]. DOI: 10.7555/JBR.29.20150121
    • (2015) J Biomed Res.
    • Hou, Y.1    Carrim, N.2    Wang, Y.3    Gallant, R.C.4    Marshall, A.5    Ni, H.6
  • 3
    • 0033050497 scopus 로고    scopus 로고
    • Relative contribution of insulin and its precursors to fibrinogen and PAI-1 in a large population with different states of glucose tolerance
    • Festa A, D'Agostino R Jr, Mykkänen L, et al.; The Insulin Resistance Atherosclerosis Study (IRAS). Relative contribution of insulin and its precursors to fibrinogen and PAI-1 in a large population with different states of glucose tolerance. Arterioscler Thromb Vasc Biol 1999;19:562-568
    • (1999) Arterioscler Thromb Vasc Biol , vol.19 , pp. 562-568
    • The Insulin Resistance Atherosclerosis Study (IRAS)1    Festa, A.2    D'Agostino, R.3    Mykkänen, L.4
  • 4
    • 84862741838 scopus 로고    scopus 로고
    • The platelet "sugar high" in diabetes
    • Ni H. The platelet "sugar high" in diabetes. Blood 2012;119:5949-5951
    • (2012) Blood , vol.119 , pp. 5949-5951
    • Ni, H.1
  • 5
    • 23644433510 scopus 로고    scopus 로고
    • Platelet function profiles in patients with type 2 diabetes and coronary artery disease on combined aspirin and clopidogrel treatment
    • Angiolillo DJ, Fernandez-Ortiz A, Bernardo E, et al. Platelet function profiles in patients with type 2 diabetes and coronary artery disease on combined aspirin and clopidogrel treatment. Diabetes 2005;54:2430-2435
    • (2005) Diabetes , vol.54 , pp. 2430-2435
    • Angiolillo, D.J.1    Fernandez-Ortiz, A.2    Bernardo, E.3
  • 6
    • 84864842497 scopus 로고    scopus 로고
    • Platelet reactivity in type 2 diabetes mellitus: A comparative analysis with survivors of myocardial infarction and the role of glycaemic control
    • Mylotte D, Kavanagh GF, Peace AJ, et al. Platelet reactivity in type 2 diabetes mellitus: a comparative analysis with survivors of myocardial infarction and the role of glycaemic control. Platelets 2012;23:439-446
    • (2012) Platelets , vol.23 , pp. 439-446
    • Mylotte, D.1    Kavanagh, G.F.2    Peace, A.J.3
  • 7
    • 34948875324 scopus 로고    scopus 로고
    • Impact of platelet reactivity on cardiovascular outcomes in patients with type 2 diabetes mellitus and coronary artery disease
    • Angiolillo DJ, Bernardo E, Sabaté M, et al. Impact of platelet reactivity on cardiovascular outcomes in patients with type 2 diabetes mellitus and coronary artery disease. J Am Coll Cardiol 2007;50:1541-1547
    • (2007) J Am Coll Cardiol , vol.50 , pp. 1541-1547
    • Angiolillo, D.J.1    Bernardo, E.2    Sabaté, M.3
  • 8
    • 84944800184 scopus 로고    scopus 로고
    • Empagliflozin, cardiovascular outcomes, and mortality in type 2 diabetes
    • Zinman B, Wanner C, Lachin JM, et al.; EMPA-REG OUTCOME Investigators. Empagliflozin, cardiovascular outcomes, and mortality in type 2 diabetes. N Engl J Med 2015;373:2117-2128
    • (2015) N Engl J Med , vol.373 , pp. 2117-2128
    • Zinman, B.1    Wanner, C.2    Lachin, J.M.3
  • 9
    • 79952273819 scopus 로고    scopus 로고
    • Long-term effects of intensive glucose lowering on cardiovascular outcomes
    • Gerstein HC, Miller ME, Genuth S, et al.; ACCORD Study Group. Long-term effects of intensive glucose lowering on cardiovascular outcomes. N Engl J Med 2011;364:818-828
    • (2011) N Engl J Med , vol.364 , pp. 818-828
    • Gerstein, H.C.1    Miller, M.E.2    Genuth, S.3
  • 10
    • 84883765959 scopus 로고    scopus 로고
    • Saxagliptin and cardiovascular outcomes in patients with type 2 diabetes mellitus
    • Scirica BM, Bhatt DL, Braunwald E, et al.; SAVOR-TIMI 53 Steering Committee and Investigators. Saxagliptin and cardiovascular outcomes in patients with type 2 diabetes mellitus. N Engl J Med 2013;369:1317-1326
    • (2013) N Engl J Med , vol.369 , pp. 1317-1326
    • Scirica, B.M.1    Bhatt, D.L.2    Braunwald, E.3
  • 11
    • 84883745765 scopus 로고    scopus 로고
    • Alogliptin after acute coronary syndrome in patients with type 2 diabetes
    • White WB, Cannon CP, Heller SR, et al.; EXAMINE Investigators. Alogliptin after acute coronary syndrome in patients with type 2 diabetes. N Engl J Med 2013;369:1327-1335
    • (2013) N Engl J Med , vol.369 , pp. 1327-1335
    • White, W.B.1    Cannon, C.P.2    Heller, S.R.3
  • 12
    • 84937053742 scopus 로고    scopus 로고
    • Effect of sitagliptin on cardiovascular outcomes in type 2 diabetes
    • Green JB, Bethel MA, Armstrong PW, et al.; TECOS Study Group. Effect of sitagliptin on cardiovascular outcomes in type 2 diabetes. N Engl J Med 2015;373:232-242
    • (2015) N Engl J Med , vol.373 , pp. 232-242
    • Green, J.B.1    Bethel, M.A.2    Armstrong, P.W.3
  • 13
    • 84890572455 scopus 로고    scopus 로고
    • Effects of glucagon-like peptide-1 receptor agonists on cardiovascular risk: A meta-analysis of randomized clinical trials
    • Monami M, Dicembrini I, Nardini C, Fiordelli I, Mannucci E. Effects of glucagon-like peptide-1 receptor agonists on cardiovascular risk: a meta-analysis of randomized clinical trials. Diabetes Obes Metab 2014;16:38-47
    • (2014) Diabetes Obes Metab , vol.16 , pp. 38-47
    • Monami, M.1    Dicembrini, I.2    Nardini, C.3    Fiordelli, I.4    Mannucci, E.5
  • 14
    • 77953108350 scopus 로고    scopus 로고
    • A systematic assessment of cardiovascular outcomes in the saxagliptin drug development program for type 2 diabetes
    • Frederich R, Alexander JH, Fiedorek FT, et al. A systematic assessment of cardiovascular outcomes in the saxagliptin drug development program for type 2 diabetes. Postgrad Med 2010;122:16-27
    • (2010) Postgrad Med , vol.122 , pp. 16-27
    • Frederich, R.1    Alexander, J.H.2    Fiedorek, F.T.3
  • 16
    • 84890572455 scopus 로고    scopus 로고
    • Effects of glucagon-like peptide-1 receptor agonists on cardiovascular risk: A metanalysis of randomised clinical trials
    • Monami M, Dicembrini I, Nardini C, Fiordelli I, Mannucci E. Effects of glucagon-like peptide-1 receptor agonists on cardiovascular risk: a metanalysis of randomised clinical trials. Diabetes Obes Metab 2014;16:38-47
    • (2014) Diabetes Obes Metab , vol.16 , pp. 38-47
    • Monami, M.1    Dicembrini, I.2    Nardini, C.3    Fiordelli, I.4    Mannucci, E.5
  • 17
    • 84868618976 scopus 로고    scopus 로고
    • Sitagliptin: Antiplatelet effect in diabetes and healthy volunteers
    • Gupta AK, Verma AK, Kailashiya J, Singh SK, Kumar N. Sitagliptin: antiplatelet effect in diabetes and healthy volunteers. Platelets 2012;23:565-570
    • (2012) Platelets , vol.23 , pp. 565-570
    • Gupta, A.K.1    Verma, A.K.2    Kailashiya, J.3    Singh, S.K.4    Kumar, N.5
  • 18
    • 33645678328 scopus 로고    scopus 로고
    • Endothelial nitric oxide synthase (eNOS) in platelets: How is it regulated and what is it doing there?
    • Randriamboavonjy V, Fleming I. Endothelial nitric oxide synthase (eNOS) in platelets: how is it regulated and what is it doing there? Pharmacol Rep 2005;57(Suppl.):59-65
    • (2005) Pharmacol Rep , vol.57 , pp. 59-65
    • Randriamboavonjy, V.1    Fleming, I.2
  • 19
    • 37549032754 scopus 로고    scopus 로고
    • Unresolved roles of platelet nitric oxide synthase
    • Naseem KM, Riba R. Unresolved roles of platelet nitric oxide synthase. J Thromb Haemost 2008;6:10-19
    • (2008) J Thromb Haemost , vol.6 , pp. 10-19
    • Naseem, K.M.1    Riba, R.2
  • 20
    • 84855428526 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 activates endothelial nitric oxide synthase in human umbilical vein endothelial cells
    • Ding L, Zhang J. Glucagon-like peptide-1 activates endothelial nitric oxide synthase in human umbilical vein endothelial cells. Acta Pharmacol Sin 2012;33:75-81
    • (2012) Acta Pharmacol Sin , vol.33 , pp. 75-81
    • Ding, L.1    Zhang, J.2
  • 21
    • 77954384449 scopus 로고    scopus 로고
    • Exendin-4 stimulates proliferation of human coronary artery endothelial cells through eNOS-, PKA- and PI3K/Akt-dependent pathways and requires GLP-1 receptor
    • Erdogdu O, Nathanson D, Sjöholm A, Nyström T, Zhang Q. Exendin-4 stimulates proliferation of human coronary artery endothelial cells through eNOS-, PKA- and PI3K/Akt-dependent pathways and requires GLP-1 receptor. Mol Cell Endocrinol 2010;325:26-35
    • (2010) Mol Cell Endocrinol , vol.325 , pp. 26-35
    • Erdogdu, O.1    Nathanson, D.2    Sjöholm, A.3    Nyström, T.4    Zhang, Q.5
  • 22
    • 84892763773 scopus 로고    scopus 로고
    • Fluorescent exendin-4 derivatives for pancreatic β-cell analysis
    • Clardy SM, Keliher EJ, Mohan JF, et al. Fluorescent exendin-4 derivatives for pancreatic β-cell analysis. Bioconjug Chem 2014;25:171-177
    • (2014) Bioconjug Chem , vol.25 , pp. 171-177
    • Clardy, S.M.1    Keliher, E.J.2    Mohan, J.F.3
  • 23
    • 79961244260 scopus 로고    scopus 로고
    • Accurate measurement of pancreatic islet beta-cell mass using a second-generation fluorescent exendin-4 analog
    • Reiner T, Thurber G, Gaglia J, et al. Accurate measurement of pancreatic islet beta-cell mass using a second-generation fluorescent exendin-4 analog. Proc Natl Acad Sci USA 2011;108:12815-12820
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 12815-12820
    • Reiner, T.1    Thurber, G.2    Gaglia, J.3
  • 24
    • 77951436599 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 receptor is present on human hepatocytes and has a direct role in decreasing hepatic steatosis in vitro by modulating elements of the insulin signaling pathway
    • Gupta NA, Mells J, Dunham RM, et al. Glucagon-like peptide-1 receptor is present on human hepatocytes and has a direct role in decreasing hepatic steatosis in vitro by modulating elements of the insulin signaling pathway. Hepatology 2010;51:1584-1592
    • (2010) Hepatology , vol.51 , pp. 1584-1592
    • Gupta, N.A.1    Mells, J.2    Dunham, R.M.3
  • 25
    • 33748753772 scopus 로고    scopus 로고
    • Fibrinogen and von Willebrand factor-independent platelet aggregation in vitro and in vivo
    • Yang H, Reheman A, Chen P, et al. Fibrinogen and von Willebrand factor-independent platelet aggregation in vitro and in vivo. J Thromb Haemost 2006;4:2230-2237
    • (2006) J Thromb Haemost , vol.4 , pp. 2230-2237
    • Yang, H.1    Reheman, A.2    Chen, P.3
  • 26
    • 61849083539 scopus 로고    scopus 로고
    • Plasma fibronectin depletion enhances platelet aggregation and thrombus formation in mice lacking fibrinogen and von Willebrand factor
    • Reheman A, Yang H, Zhu G, et al. Plasma fibronectin depletion enhances platelet aggregation and thrombus formation in mice lacking fibrinogen and von Willebrand factor. Blood 2009;113:1809-1817
    • (2009) Blood , vol.113 , pp. 1809-1817
    • Reheman, A.1    Yang, H.2    Zhu, G.3
  • 27
    • 0033838314 scopus 로고    scopus 로고
    • Persistence of platelet thrombus formation in arterioles of mice lacking both von Willebrand factor and fibrinogen
    • Ni H, Denis CV, Subbarao S, et al. Persistence of platelet thrombus formation in arterioles of mice lacking both von Willebrand factor and fibrinogen. J Clin Invest 2000;106:385-392
    • (2000) J Clin Invest , vol.106 , pp. 385-392
    • Ni, H.1    Denis, C.V.2    Subbarao, S.3
  • 28
    • 0029958404 scopus 로고    scopus 로고
    • Glucose intolerance but normal satiety in mice with a null mutation in the glucagon-like peptide 1 receptor gene
    • Scrocchi LA, Brown TJ, MaClusky N, et al. Glucose intolerance but normal satiety in mice with a null mutation in the glucagon-like peptide 1 receptor gene. Nat Med 1996;2:1254-1258
    • (1996) Nat Med , vol.2 , pp. 1254-1258
    • Scrocchi, L.A.1    Brown, T.J.2    MaClusky, N.3
  • 29
    • 79551488587 scopus 로고    scopus 로고
    • Exendin-4, a glucagon-like peptide-1 receptor agonist, reduces intimal thickening after vascular injury
    • Goto H, Nomiyama T, Mita T, et al. Exendin-4, a glucagon-like peptide-1 receptor agonist, reduces intimal thickening after vascular injury. Biochem Biophys Res Commun 2011;405:79-84
    • (2011) Biochem Biophys Res Commun , vol.405 , pp. 79-84
    • Goto, H.1    Nomiyama, T.2    Mita, T.3
  • 30
    • 77951151612 scopus 로고    scopus 로고
    • Inhibition of monocyte adhesion to endothelial cells and attenuation of atherosclerotic lesion by a glucagon-like peptide-1 receptor agonist, exendin-4
    • Arakawa M, Mita T, Azuma K, et al. Inhibition of monocyte adhesion to endothelial cells and attenuation of atherosclerotic lesion by a glucagon-like peptide-1 receptor agonist, exendin-4. Diabetes 2010;59:1030-1037
    • (2010) Diabetes , vol.59 , pp. 1030-1037
    • Arakawa, M.1    Mita, T.2    Azuma, K.3
  • 31
    • 84893185728 scopus 로고    scopus 로고
    • Anfibatide, a novel GPIb complex antagonist, inhibits platelet adhesion and thrombus formation in vitro and in vivo in murine models of thrombosis
    • Lei X, Reheman A, Hou Y, et al. Anfibatide, a novel GPIb complex antagonist, inhibits platelet adhesion and thrombus formation in vitro and in vivo in murine models of thrombosis. Thromb Haemost 2014;111:279-289
    • (2014) Thromb Haemost , vol.111 , pp. 279-289
    • Lei, X.1    Reheman, A.2    Hou, Y.3
  • 32
    • 84907487892 scopus 로고    scopus 로고
    • Plasma fibronectin supports hemostasis and regulates thrombosis
    • Wang Y, Reheman A, Spring CM, et al. Plasma fibronectin supports hemostasis and regulates thrombosis. J Clin Invest 2014;124:4281-4293
    • (2014) J Clin Invest , vol.124 , pp. 4281-4293
    • Wang, Y.1    Reheman, A.2    Spring, C.M.3
  • 33
    • 84871675071 scopus 로고    scopus 로고
    • The glucagon-like peptide-1 receptor - Or not?
    • Pyke C, Knudsen LB. The glucagon-like peptide-1 receptor - or not? Endocrinology 2013;154:4-8
    • (2013) Endocrinology , vol.154 , pp. 4-8
    • Pyke, C.1    Knudsen, L.B.2
  • 34
    • 67650682753 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 induced signaling and insulin secretion do not drive fuel and energy metabolism in primary rodent pancreatic beta-cells
    • Peyot ML, Gray JP, Lamontagne J, et al. Glucagon-like peptide-1 induced signaling and insulin secretion do not drive fuel and energy metabolism in primary rodent pancreatic beta-cells. PLoS One 2009;4:e6221
    • (2009) PLoS One , vol.4
    • Peyot, M.L.1    Gray, J.P.2    Lamontagne, J.3
  • 35
    • 50449094096 scopus 로고    scopus 로고
    • Glucose and GLP-1 stimulate cAMP production via distinct adenylyl cyclases in INS-1E insulinoma cells
    • Ramos LS, Zippin JH, Kamenetsky M, Buck J, Levin LR. Glucose and GLP-1 stimulate cAMP production via distinct adenylyl cyclases in INS-1E insulinoma cells. J Gen Physiol 2008;132:329-338
    • (2008) J Gen Physiol , vol.132 , pp. 329-338
    • Ramos, L.S.1    Zippin, J.H.2    Kamenetsky, M.3    Buck, J.4    Levin, L.R.5
  • 37
    • 84877917989 scopus 로고    scopus 로고
    • Enhanced platelet activity and thrombosis in a murine model of type I diabetes are partially insulin-like growth factor 1-dependent and phosphoinositide 3-kinase-dependent
    • Stolla MC, Li D, Lu L, Woulfe DS. Enhanced platelet activity and thrombosis in a murine model of type I diabetes are partially insulin-like growth factor 1-dependent and phosphoinositide 3-kinase-dependent. J Thromb Haemost 2013;11:919-929
    • (2013) J Thromb Haemost , vol.11 , pp. 919-929
    • Stolla, M.C.1    Li, D.2    Lu, L.3    Woulfe, D.S.4
  • 38
    • 84897569638 scopus 로고    scopus 로고
    • Exenatide induces aortic vasodilation increasing hydrogen sulphide, carbon monoxide and nitric oxide production
    • Sélley E, Kun S, Szijártó IA, et al. Exenatide induces aortic vasodilation increasing hydrogen sulphide, carbon monoxide and nitric oxide production. Cardiovasc Diabetol 2014;13:69
    • (2014) Cardiovasc Diabetol , vol.13 , pp. 69
    • Sélley, E.1    Kun, S.2    Szijártó, I.A.3
  • 39
    • 76749159335 scopus 로고    scopus 로고
    • A novel antihypertensive effect of exenatide, a GLP-1 agonist
    • Dandona P, Chaudhuri A, Dhindsa S. A novel antihypertensive effect of exenatide, a GLP-1 agonist. Am J Hypertens 2010;23:228
    • (2010) Am J Hypertens , vol.23 , pp. 228
    • Dandona, P.1    Chaudhuri, A.2    Dhindsa, S.3
  • 40
    • 84871936025 scopus 로고    scopus 로고
    • Dipeptidyl peptidase-4 inhibitors and cardiovascular risk: A meta-analysis of randomized clinical trials
    • Monami M, Ahrén B, Dicembrini I, Mannucci E. Dipeptidyl peptidase-4 inhibitors and cardiovascular risk: a meta-analysis of randomized clinical trials. Diabetes Obes Metab 2013;15:112-120
    • (2013) Diabetes Obes Metab , vol.15 , pp. 112-120
    • Monami, M.1    Ahrén, B.2    Dicembrini, I.3    Mannucci, E.4
  • 41
    • 84948740668 scopus 로고    scopus 로고
    • Lixisenatide in patients with type 2 diabetes and acute coronary syndrome
    • Pfeffer MA, Claggett B, Diaz R, et al.; ELIXA Investigators. Lixisenatide in patients with type 2 diabetes and acute coronary syndrome. N Engl J Med 2015;373:2247-2257
    • (2015) N Engl J Med , vol.373 , pp. 2247-2257
    • Pfeffer, M.A.1    Claggett, B.2    Diaz, R.3
  • 42
    • 84871686739 scopus 로고    scopus 로고
    • GLP-1 receptor activation indirectly reduces hepatic lipid accumulation but does not attenuate development of atherosclerosis in diabetic male ApoE(-/-) mice
    • Panjwani N, Mulvihill EE, Longuet C, et al. GLP-1 receptor activation indirectly reduces hepatic lipid accumulation but does not attenuate development of atherosclerosis in diabetic male ApoE(-/-) mice. Endocrinology 2013;154:127-139
    • (2013) Endocrinology , vol.154 , pp. 127-139
    • Panjwani, N.1    Mulvihill, E.E.2    Longuet, C.3
  • 43
    • 47649095282 scopus 로고    scopus 로고
    • NO-synthase-/NO-independent regulation of human and murine platelet soluble guanylyl cyclase activity
    • Gambaryan S, Kobsar A, Hartmann S, et al. NO-synthase-/NO-independent regulation of human and murine platelet soluble guanylyl cyclase activity. J Thromb Haemost 2008;6:1376-1384
    • (2008) J Thromb Haemost , vol.6 , pp. 1376-1384
    • Gambaryan, S.1    Kobsar, A.2    Hartmann, S.3
  • 44
    • 84949758990 scopus 로고    scopus 로고
    • The spatiotemporal regulation of cAMP signaling in blood platelets-old friends and new players
    • Raslan Z, Aburima A, Naseem KM. The spatiotemporal regulation of cAMP signaling in blood platelets-old friends and new players. Front Pharmacol 2015;6:266
    • (2015) Front Pharmacol , vol.6 , pp. 266
    • Raslan, Z.1    Aburima, A.2    Naseem, K.M.3
  • 45
    • 84897012538 scopus 로고    scopus 로고
    • Time-resolved characterization of cAMP/PKA-dependent signaling reveals that platelet inhibition is a concerted process involving multiple signaling pathways
    • Beck F, Geiger J, Gambaryan S, et al. Time-resolved characterization of cAMP/PKA-dependent signaling reveals that platelet inhibition is a concerted process involving multiple signaling pathways. Blood 2014;123:e1-e10
    • (2014) Blood , vol.123 , pp. e1-e10
    • Beck, F.1    Geiger, J.2    Gambaryan, S.3
  • 46
    • 84875715176 scopus 로고    scopus 로고
    • Intrinsic platelet reactivity and thrombus burden in patients with ST-elevation myocardial infarction
    • Alexopoulos D, Xanthopoulou I, Tsigkas G, et al. Intrinsic platelet reactivity and thrombus burden in patients with ST-elevation myocardial infarction. Thromb Res 2013;131:333-337
    • (2013) Thromb Res , vol.131 , pp. 333-337
    • Alexopoulos, D.1    Xanthopoulou, I.2    Tsigkas, G.3
  • 48
    • 78549272749 scopus 로고    scopus 로고
    • Platelet CD40L mediates thrombotic and inflammatory processes in atherosclerosis
    • Lievens D, Zernecke A, Seijkens T, et al. Platelet CD40L mediates thrombotic and inflammatory processes in atherosclerosis. Blood 2010;116:4317-4327
    • (2010) Blood , vol.116 , pp. 4317-4327
    • Lievens, D.1    Zernecke, A.2    Seijkens, T.3
  • 49
    • 84877356252 scopus 로고    scopus 로고
    • Cholesterol efflux in megakaryocyte progenitors suppresses platelet production and thrombocytosis
    • Murphy AJ, Bijl N, Yvan-Charvet L, et al. Cholesterol efflux in megakaryocyte progenitors suppresses platelet production and thrombocytosis. Nat Med 2013;19:586-594
    • (2013) Nat Med , vol.19 , pp. 586-594
    • Murphy, A.J.1    Bijl, N.2    Yvan-Charvet, L.3
  • 50
    • 79953826349 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 receptor agonist ameliorates renal injury through its anti-inflammatory action without lowering blood glucose level in a rat model of type 1 diabetes
    • Kodera R, Shikata K, Kataoka HU, et al. Glucagon-like peptide-1 receptor agonist ameliorates renal injury through its anti-inflammatory action without lowering blood glucose level in a rat model of type 1 diabetes. Diabetologia 2011;54:965-978
    • (2011) Diabetologia , vol.54 , pp. 965-978
    • Kodera, R.1    Shikata, K.2    Kataoka, H.U.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.