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Volumn 98, Issue 3-4, 2016, Pages 111-114
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Bosentan Pharmacokinetics in Pediatric Patients with Pulmonary Arterial Hypertension: Comparison of Dried Blood Spot and Plasma Analysis
a
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Author keywords
Bosentan; Dried blood spots; Pediatrics; Pharmacokinetics; Pulmonary arterial hypertension
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Indexed keywords
BOSENTAN;
DRUG METABOLITE;
RO 47 8634;
RO 48 5033;
RO 64 1056;
UNCLASSIFIED DRUG;
ANTIHYPERTENSIVE AGENT;
SULFONAMIDE;
AREA UNDER THE CURVE;
ARTICLE;
BLOOD-TO-PLASMA RATIO;
CONTROLLED STUDY;
DOSAGE SCHEDULE COMPARISON;
DRIED BLOOD SPOT TESTING;
DRUG BLOOD LEVEL;
DRUG DOSE REGIMEN;
GEOMETRIC MEAN RATIO;
HUMAN;
LIMIT OF QUANTITATION;
MAJOR CLINICAL STUDY;
MATHEMATICAL PARAMETERS;
MAXIMUM PLASMA CONCENTRATION;
MULTICENTER STUDY (TOPIC);
MULTIPLE DRUG DOSE;
PARTITION RATIO;
PEDIATRIC CARDIOLOGY;
PHASE 3 CLINICAL TRIAL (TOPIC);
PLASMA;
PLASMA CONCENTRATION-TIME CURVE;
PRIORITY JOURNAL;
PULMONARY HYPERTENSION;
RANDOMIZED CONTROLLED TRIAL (TOPIC);
TIME TO MAXIMUM PLASMA CONCENTRATION;
BLOOD;
CHILD;
CLINICAL TRIAL;
COMPARATIVE STUDY;
DRUG EFFECTS;
FEMALE;
HYPERTENSION, PULMONARY;
MALE;
METABOLISM;
MULTICENTER STUDY;
PHASE 3 CLINICAL TRIAL;
PROCEDURES;
RANDOMIZED CONTROLLED TRIAL;
STANDARDS;
ANTIHYPERTENSIVE AGENTS;
CHILD;
DRIED BLOOD SPOT TESTING;
FEMALE;
HUMANS;
HYPERTENSION, PULMONARY;
MALE;
PLASMA;
SULFONAMIDES;
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EID: 84969752534
PISSN: 00317012
EISSN: 14230313
Source Type: Journal
DOI: 10.1159/000446583 Document Type: Article |
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Times cited : (4)
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References (6)
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