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Volumn 17, Issue 4, 2016, Pages 494-510

Meta-analysis of the efficacy and safety of prazosin versus placebo for the treatment of nightmares and sleep disturbances in adults with posttraumatic stress disorder

Author keywords

Nightmares; posttraumatic stress disorder; prazosin; sleep disturbance

Indexed keywords

PLACEBO; PRAZOSIN; ALPHA 1 ADRENERGIC RECEPTOR BLOCKING AGENT;

EID: 84969651081     PISSN: 15299732     EISSN: 15299740     Source Type: Journal    
DOI: 10.1080/15299732.2016.1141150     Document Type: Review
Times cited : (62)

References (22)
  • 1
    • 84923181110 scopus 로고    scopus 로고
    • Comparing the effect of prazosin and hydroxyzine on sleep quality in patients suffering from posttraumatic stress disorder
    • M.Ahmadpanah,, P.Sabzeiee,, S.M.Hosseini,, S.M.Hosseini,, S.Torabian,, M.Haghighi,, … S.Brand, (2014). Comparing the effect of prazosin and hydroxyzine on sleep quality in patients suffering from posttraumatic stress disorder. Neuropsychobiology, 69(4), 235–242. doi:10.1159/000362243
    • (2014) Neuropsychobiology , vol.69 , Issue.4 , pp. 235-242
    • Ahmadpanah, M.1    Sabzeiee, P.2    Hosseini, S.M.3    Hosseini, S.M.4    Torabian, S.5    Haghighi, M.6    Brand, S.7
  • 4
    • 84945910436 scopus 로고    scopus 로고
    • Targeting the noradrenergic system in posttraumatic stress disorder: A systematic review and meta-analysis of prazosin trials
    • D.De Berardis,, S.Marini,, N.Serroni,, F.Iasevoli,, C.Tomasetti,, A.Bartolomeis,, … M.D.Giannantonio, (2015). Targeting the noradrenergic system in posttraumatic stress disorder: A systematic review and meta-analysis of prazosin trials. Current Drug Targets, 16(10), 1094–1106. doi:10.2174/1389450116666150506114108
    • (2015) Current Drug Targets , vol.16 , Issue.10 , pp. 1094-1106
    • De Berardis, D.1    Marini, S.2    Serroni, N.3    Iasevoli, F.4    Tomasetti, C.5    Bartolomeis, A.6    Giannantonio, M.D.7
  • 5
    • 84856215953 scopus 로고    scopus 로고
    • Placebo-controlled comparison of prazosin and cognitive-behavioral treatments for sleep disturbances in US military veterans
    • A.Germain,, R.Richardson,, D.E.Moul,, O.Mammen,, G.Haas,, S.D.Forman,, … E.A.Nofzinger, (2012). Placebo-controlled comparison of prazosin and cognitive-behavioral treatments for sleep disturbances in US military veterans. Journal of Psychosomatic Research, 72(2), 89–96. doi:10.1016/j.jpsychores.2011.11.010
    • (2012) Journal of Psychosomatic Research , vol.72 , Issue.2 , pp. 89-96
    • Germain, A.1    Richardson, R.2    Moul, D.E.3    Mammen, O.4    Haas, G.5    Forman, S.D.6    Nofzinger, E.A.7
  • 6
    • 78751472155 scopus 로고    scopus 로고
    • Retrieved from
    • J.L.Gradus, (2015). Epidemiology of PTSD. Retrieved from http://www.ptsd.va.gov/professional/PTSD-overview/epidemiological-facts-ptsd.asp
    • (2015) Epidemiology of PTSD
    • Gradus, J.L.1
  • 8
    • 84905004690 scopus 로고    scopus 로고
    • Prazosin in the treatment of PTSD
    • B.Green, (2014). Prazosin in the treatment of PTSD. Journal of Psychiatric Practice, 20(4), 253–259. doi:10.1097/01.pra.0000452561.98286.1e
    • (2014) Journal of Psychiatric Practice , vol.20 , Issue.4 , pp. 253-259
    • Green, B.1
  • 10
    • 33745610463 scopus 로고    scopus 로고
    • Sleep disturbances in patients with post-traumatic stress disorder: Epidemiology, impact and approaches to management
    • M.J.Maher,, S.A.Rego,, & G.M.Asnis, (2006). Sleep disturbances in patients with post-traumatic stress disorder: Epidemiology, impact and approaches to management. CNS Drugs, 20(7), 567–590. doi:10.2165/00023210-200620070-00003
    • (2006) CNS Drugs , vol.20 , Issue.7 , pp. 567-590
    • Maher, M.J.1    Rego, S.A.2    Asnis, G.M.3
  • 11
    • 0344826500 scopus 로고    scopus 로고
    • Prescribing patterns for patients with posttraumatic stress disorder
    • T.A.Mellman,, R.E.Clark,, & W.J.Peacock, (2003). Prescribing patterns for patients with posttraumatic stress disorder. Psychiatric Services, 54(12), 1618–1621. doi:10.1176/appi.ps.54.12.1618
    • (2003) Psychiatric Services , vol.54 , Issue.12 , pp. 1618-1621
    • Mellman, T.A.1    Clark, R.E.2    Peacock, W.J.3
  • 12
    • 33947587104 scopus 로고    scopus 로고
    • A parallel group placebo controlled study of prazosin for trauma nightmares and sleep disturbance in combat veterans with post-traumatic stress disorder
    • M.A.Raskind,, E.R.Peskind,, D.J.Hoff,, K.L.Hart,, H.A.Holmes,, D.Warren,, … M.E.McFall, (2007). A parallel group placebo controlled study of prazosin for trauma nightmares and sleep disturbance in combat veterans with post-traumatic stress disorder. Biological Psychiatry, 61(8), 928–934. doi:10.1016/j.biopsych.2006.06.032
    • (2007) Biological Psychiatry , vol.61 , Issue.8 , pp. 928-934
    • Raskind, M.A.1    Peskind, E.R.2    Hoff, D.J.3    Hart, K.L.4    Holmes, H.A.5    Warren, D.6    McFall, M.E.7
  • 14
    • 84883689561 scopus 로고    scopus 로고
    • A trial of prazosin for combat trauma PTSD with nightmares in active-duty soldiers returned from Iraq and Afghanistan
    • M.A.Raskind,, K.Peterson,, T.Williams,, D.J.Hoff,, K.Hart,, H.Holmes,, … E.R.Peskind, (2013). A trial of prazosin for combat trauma PTSD with nightmares in active-duty soldiers returned from Iraq and Afghanistan. American Journal of Psychiatry, 170(9), 1003–1010. doi:10.1176/appi.ajp.2013.12081133
    • (2013) American Journal of Psychiatry , vol.170 , Issue.9 , pp. 1003-1010
    • Raskind, M.A.1    Peterson, K.2    Williams, T.3    Hoff, D.J.4    Hart, K.5    Holmes, H.6    Peskind, E.R.7
  • 15
    • 84907186615 scopus 로고    scopus 로고
    • Posttraumatic stress disorder in adults: Impact, comorbidity, risk factors, and treatment
    • J.Sareen, (2014). Posttraumatic stress disorder in adults: Impact, comorbidity, risk factors, and treatment. Canadian Journal of Psychiatry/Revue Canadienne De Psychiatrie, 59(9), 460–467.
    • (2014) Canadian Journal of Psychiatry/Revue Canadienne De Psychiatrie , vol.59 , Issue.9 , pp. 460-467
    • Sareen, J.1
  • 16
    • 84921033853 scopus 로고    scopus 로고
    • Comparative meta-analysis of prazosin and imagery rehearsal therapy for nightmare frequency, sleep quality, and posttraumatic stress
    • G.Seda,, M.M.Sanchez-Ortuno,, C.H.Welsh,, A.C.Halbower,, & J.D.Edinger, (2015). Comparative meta-analysis of prazosin and imagery rehearsal therapy for nightmare frequency, sleep quality, and posttraumatic stress. Journal of Clinical Sleep Medicine, 11(1), 11–22.
    • (2015) Journal of Clinical Sleep Medicine , vol.11 , Issue.1 , pp. 11-22
    • Seda, G.1    Sanchez-Ortuno, M.M.2    Welsh, C.H.3    Halbower, A.C.4    Edinger, J.D.5
  • 17
    • 70449553405 scopus 로고    scopus 로고
    • Persistent nightmares are associated with repeat suicide attempt: A prospective study
    • N.Sjostrom,, J.Hetta,, & M.Waern, (2009). Persistent nightmares are associated with repeat suicide attempt: A prospective study. Psychiatry Research, 170(2–3), 208–211. doi:10.1016/j.psychres.2008.09.006
    • (2009) Psychiatry Research , vol.170 , Issue.2-3 , pp. 208-211
    • Sjostrom, N.1    Hetta, J.2    Waern, M.3
  • 18
    • 78649719150 scopus 로고    scopus 로고
    • The neural correlates and temporal sequence of the relationship between shock exposure, disturbed sleep and impaired consolidation of fear extinction
    • V.I.Spoormaker,, A.Sturm,, K.C.Andrade,, M.S.Schroter,, A.Sturm,, R.Goya-Maldonado,, … M.Czisch, (2010). The neural correlates and temporal sequence of the relationship between shock exposure, disturbed sleep and impaired consolidation of fear extinction. Journal of Psychiatric Research, 44(16), 1121–1128. doi:10.1016/j.jpsychires.2010.04.017
    • (2010) Journal of Psychiatric Research , vol.44 , Issue.16 , pp. 1121-1128
    • Spoormaker, V.I.1    Sturm, A.2    Andrade, K.C.3    Schroter, M.S.4    Sturm, A.5    Goya-Maldonado, R.6    Czisch, M.7
  • 19
    • 39449113662 scopus 로고    scopus 로고
    • Prazosin effects on objective sleep measures and clinical symptoms in civilian trauma posttraumatic stress disorder: A placebo-controlled study
    • F.B.Taylor,, P.Martin,, C.Thompson,, J.Williams,, T.A.Mellman,, C.Gross,, … M.A.Raskind, (2008). Prazosin effects on objective sleep measures and clinical symptoms in civilian trauma posttraumatic stress disorder: A placebo-controlled study. Biological Psychiatry, 63(6), 629–632. doi:10.1016/j.biopsych.2007.07.001
    • (2008) Biological Psychiatry , vol.63 , Issue.6 , pp. 629-632
    • Taylor, F.B.1    Martin, P.2    Thompson, C.3    Williams, J.4    Mellman, T.A.5    Gross, C.6    Raskind, M.A.7
  • 20
    • 0036007450 scopus 로고    scopus 로고
    • The alpha-adrenergic antagonist prazosin improves sleep and nightmares in civilian trauma posttraumatic stress disorder
    • F.B.Taylor,, & M.A.Raskind, (2002). The alpha-adrenergic antagonist prazosin improves sleep and nightmares in civilian trauma posttraumatic stress disorder. Journal of Clinical Psychopharmacology, 22(1), 82–85. doi:10.1097/00004714-200202000-00013
    • (2002) Journal of Clinical Psychopharmacology , vol.22 , Issue.1 , pp. 82-85
    • Taylor, F.B.1    Raskind, M.A.2
  • 21
    • 0034029707 scopus 로고    scopus 로고
    • Comparison of prazosin, terazosin and tamsulosin in the treatment of symptomatic benign prostatic hyperplasia: A short-term open, randomized multicenter study
    • T.Tsujii, (2000). Comparison of prazosin, terazosin and tamsulosin in the treatment of symptomatic benign prostatic hyperplasia: A short-term open, randomized multicenter study. International Journal of Urology, 7(6), 199–205. doi:10.1046/j.1442-2042.2000.00175.x
    • (2000) International Journal of Urology , vol.7 , Issue.6 , pp. 199-205
    • Tsujii, T.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.