Extensively drug-resistant Acinetobacter baumannii outbreak cross-transmitted in an intensive care unit and respiratory intensive care unit

American Journal of Infection Control

Volumn 44, Issue 11, 2016, Pages 1280-1284

  Lei, Jin'e ^a,b,c   Han, Shaoshan ^c   Wu, Wenjing ^c   Wang, Xue ^c   Xu, Jiru ^a,b   Han, Lei ^a,b  

^a MEDICAL SCHOOL OF XI AN JIAOTONG UNIVERSITY   (China)

^b XI'AN JIAOTONG UNIVERSITY   (China)

^c THE FIRST AFFILIATED HOSPITAL OF XI AN JIAOTONG UNIVERSITY   (China)

Author keywords

cross transmit; Extensively drug resistant Acinetobacter baumannii; intensive care unit; outbreak; respiratory intensive care unit

Indexed keywords

AMIKACIN; AMPICILLIN; AZTREONAM; CEFAZOLIN; CEFEPIME; CEFOPERAZONE PLUS SULBACTAM; CEFOTETAN; CEFTAZIDIME; CEFTRIAXONE; CEFUROXIME; CIPROFLOXACIN; COLISTIN; COTRIMOXAZOLE; GENTAMICIN; IMIPENEM; LEVOFLOXACIN; MEROPENEM; NITROFURANTOIN; PIPERACILLIN; PIPERACILLIN PLUS TAZOBACTAM; SULTAMICILLIN; TIGECYCLINE; TOBRAMYCIN;

ABDOMINAL DRAINAGE; ACINETOBACTER BAUMANNII; ACINETOBACTER INFECTION; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL STRAIN; BACTERIUM ISOLATION; BLOOD CULTURE; BODY FLUID; BRONCHIAL ASPIRATION PROCEDURE; BROTH DILUTION; CLINICAL ARTICLE; DISEASE SURVEILLANCE; DISEASE TRANSMISSION; DISINFECTION; EPIDEMIC; EXTENSIVELY DRUG RESISTANT ACINETOBACTER BAUMANNII; GENOTYPING TECHNIQUE; HOSPITAL HYGIENE; HUMAN; INFECTION CONTROL; INTENSIVE CARE UNIT; LUNG LAVAGE; MICROBIOLOGICAL EXAMINATION; MINIMUM INHIBITORY CONCENTRATION; MULTILOCUS SEQUENCE TYPING; SPUTUM CULTURE; URINE CULTURE; WOUND FLUID; AGED; CASE REPORT; CLASSIFICATION; CROSS INFECTION; DRUG EFFECTS; FEMALE; GENETICS; GENOTYPE; ISOLATION AND PURIFICATION; MALE; MICROBIAL SENSITIVITY TEST; MIDDLE AGED; MULTIDRUG RESISTANCE; TERTIARY CARE CENTER; TRANSMISSION; VERY ELDERLY;

ACINETOBACTER BAUMANNII; ACINETOBACTER INFECTIONS; AGED; AGED, 80 AND OVER; CROSS INFECTION; DISEASE OUTBREAKS; DISEASE TRANSMISSION, INFECTIOUS; DRUG RESISTANCE, MULTIPLE, BACTERIAL; FEMALE; GENOTYPE; HUMANS; INTENSIVE CARE UNITS; MALE; MICROBIAL SENSITIVITY TESTS; MIDDLE AGED; MULTILOCUS SEQUENCE TYPING; TERTIARY CARE CENTERS;

EID: 84969169380     PISSN: 01966553     EISSN: 15273296     Source Type: Journal    
DOI: 10.1016/j.ajic.2016.03.041     Document Type: Article

References (26)

1. 1 Karageorgopoulos, D.E., Falagas, M.E., Current control and treatment of multidrug-resistant Acinetobacter baumannii infections. Lancet Infect Dis 8 (2008), 751–762.
2. 2 Peleg, A.Y., Seifert, H., Paterson, D.L., Acinetobacter baumannii: emergence of a successful pathogen. Clin Microbiol Rev 21 (2008), 538–582.
3. 3 Espinal, P., Macia, M.D., Roca, I., Gato, E., Ruiz, E., Fernandez-Cuenca, F., et al. First report of an OXA-23 carbapenemase-producing Acinetobacter baumannii clinical isolate related to Tn2006 in Spain. Antimicrob Agents Chemother 57 (2013), 589–591.
4. 4 Cristina, M.L., Spagnolo, A.M., Ottria, G., Sartini, M., Orlando, P., Perdelli, F., Spread of multidrug carbapenem-resistant Acinetobacter baumannii in different wards of an Italian hospital. Am J Infect Control 39 (2011), 790–794.
5. 5 Kohlenberg, A., Brummer, S., Higgins, P.G., Sohr, D., Piening, B.C., de Grahl, C., et al. Outbreak of carbapenem-resistant Acinetobacter baumannii carrying the carbapenemase OXA-23 in a German university medical centre. J Med Microbiol 58 (2009), 1499–1507.
6. 6 Magiorakos, A.P., Srinivasan, A., Carey, R.B., Carmeli, Y., Falagas, M.E., Giske, C.G., et al. Multidrug-resistant, extensively drug-resistant and pandrug-resistant bacteria: an international expert proposal for interim standard definitions for acquired resistance. Clin Microbiol Infect 18 (2012), 268–281.
7. 7 Higgins, P.G., Wisplinghoff, H., Krut, O., Seifert, H., A PCR-based method to differentiate between Acinetobacter baumannii and Acinetobacter genomic species 13TU. Clin Microbiol Infect 13 (2007), 1199–1201.
8. 8 CLSI, Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically; approved standard-ninth edition (M07-A9). 2012, CLSI, Wayne (PA).
9. 9 Livermore, D.M., Hope, R., Brick, G., Lillie, M., Reynolds, R., Non-susceptibility trends among Pseudomonas aeruginosa and other non-fermentative Gram-negative bacteria from bacteraemias in the UK and Ireland, 2001-06. J Antimicrob Chemother 62:Suppl (2008), ii55–63.
10. 10 Rossolini, G.M., Mantengoli, E., Antimicrobial resistance in Europe and its potential impact on empirical therapy. Clin Microbiol Infect 14:Suppl (2008), 2–8.
11. 11 Morgan, D.J., Weisenberg, S.A., Augenbraun, M.H., Calfee, D.P., Currie, B.P., Furuya, E.Y., et al. Multidrug-resistant Acinetobacter baumannii in New York City—10 years into the epidemic. Infect Control Hosp Epidemiol 30 (2009), 196–197.
12. 12 Vilacoba, E., Almuzara, M., Gulone, L., Rodriguez, R., Pallone, E., Bakai, R., et al. Outbreak of extensively drug-resistant Acinetobacter baumannii indigo-pigmented strains. J Clin Microbiol 51 (2013), 3726–3730.
13. 13 Zarrilli, R., Di Popolo, A., Bagattini, M., Giannouli, M., Martino, D., Barchitta, M., et al. Clonal spread and patient risk factors for acquisition of extensively drug-resistant Acinetobacter baumannii in a neonatal intensive care unit in Italy. J Hosp Infect 82 (2012), 260–265.
14. 14 Viehman, J.A., Nguyen, M.H., Doi, Y., Treatment options for carbapenem-resistant and extensively drug-resistant Acinetobacter baumannii infections. Drugs 74 (2014), 1315–1333.
15. 15 Roca, I., Espinal, P., Vila-Farres, X., Vila, J., The Acinetobacter baumannii oxymoron: commensal hospital dweller turned pan-drug-resistant menace. Front Microbiol, 3, 2012, 148.
16. 16 Manchanda, V., Sanchaita, S., Singh, N., Multidrug resistant Acinetobacter. J Glob Infect Dis 2 (2010), 291–304.
17. 17 Ye, D., Shan, J., Huang, Y., Li, J., Li, C., Liu, X., et al. A gloves-associated outbreak of imipenem-resistant Acinetobacter baumannii in an intensive care unit in Guangdong, China. BMC Infect Dis, 15, 2015, 179.
18. 18 Liang, W., Liu, X.F., Huang, J., Zhu, D.M., Li, J., Zhang, J., Activities of colistin- and minocycline-based combinations against extensive drug resistant Acinetobacter baumannii isolates from intensive care unit patients. BMC Infect Dis, 11, 2011, 109.
19. 19 Wareham, D.W., Gordon, N.C., Hornsey, M., In vitro activity of teicoplanin combined with colistin versus multidrug-resistant strains of Acinetobacter baumannii. J Antimicrob Chemother 66 (2011), 1047–1051.
20. 20 Gordon, N.C., Png, K., Wareham, D.W., Potent synergy and sustained bactericidal activity of a vancomycin-colistin combination versus multidrug-resistant strains of Acinetobacter baumannii. Antimicrob Agents Chemother 54 (2010), 5316–5322.
21. 21 Principe, L., D'Arezzo, S., Capone, A., Petrosillo, N., Visca, P., In vitro activity of tigecycline in combination with various antimicrobials against multidrug resistant Acinetobacter baumannii. Ann Clin Microbiol Antimicrob, 8, 2009, 18.
22. 22 Ozbek, B., Senturk, A., Postantibiotic effects of tigecycline, colistin sulfate, and levofloxacin alone or tigecycline-colistin sulfate and tigecycline-levofloxacin combinations against Acinetobacter baumannii. Chemotherapy 56 (2010), 466–471.
23. 23 Wei, W., Yang, H., Liu, Y., Ye, Y., Li, J., In vitro synergy of colistin combinations against extensively drug-resistant Acinetobacter baumannii producing OXA-23 carbapenemase. J Chemother, 2016, 10.1179/1973947815Y.0000000030 in press.
24. 24 Inchai, J., Liwsrisakun, C., Theerakittikul, T., Chaiwarith, R., Khositsakulchai, W., Pothirat, C., Risk factors of multidrug-resistant, extensively drug-resistant and pandrug-resistant Acinetobacter baumannii ventilator-associated pneumonia in a medical intensive care unit of university hospital in Thailand. J Infect Chemother 21 (2015), 570–574.
25. 25 Akajagbor, D.S., Wilson, S.L., Shere-Wolfe, K.D., Dakum, P., Charurat, M.E., Gilliam, B.L., Higher incidence of acute kidney injury with intravenous colistimethate sodium compared with polymyxin B in critically ill patients at a tertiary care medical center. Clin Infect Dis 57 (2013), 1300–1303.
26. 26 Markogiannakis, A., Fildisis, G., Tsiplakou, S., Ikonomidis, A., Koutsoukou, A., Pournaras, S., et al. Cross-transmission of multidrug-resistant Acinetobacter baumannii clonal strains causing episodes of sepsis in a trauma intensive care unit. Infect Control Hosp Epidemiol 29 (2008), 410–417.