-
1
-
-
4644324025
-
Cancer immunotherapy: Moving beyond current vaccines
-
Rosenberg SA, Yang JC, Restifo NP. Cancer immunotherapy: moving beyond current vaccines. Nat. Med. 10(9), 909-915 (2004).
-
(2004)
Nat. Med.
, vol.10
, Issue.9
, pp. 909-915
-
-
Rosenberg, S.A.1
Yang, J.C.2
Restifo, N.P.3
-
2
-
-
84924902841
-
Immunologic checkpoints in cancer therapy: Focus on the programmed death-1 (PD-1) receptor pathway
-
Momtaz P, Postow MA. Immunologic checkpoints in cancer therapy: focus on the programmed death-1 (PD-1) receptor pathway. Pharmgenomics Pers. Med. 7, 357 (2014).
-
(2014)
Pharmgenomics Pers. Med.
, vol.7
, pp. 357
-
-
Momtaz, P.1
Postow, M.A.2
-
3
-
-
77954801079
-
Improved survival with ipilimumab in patients with metastatic melanoma
-
Hodi FS, O'day SJ, Mcdermott DF et al. Improved survival with ipilimumab in patients with metastatic melanoma. N. Engl. J. Med. 363(8), 711-723 (2010).
-
(2010)
N. Engl. J. Med.
, vol.363
, Issue.8
, pp. 711-723
-
-
Hodi, F.S.1
O'Day, S.J.2
Mcdermott, D.F.3
-
4
-
-
79959772576
-
Ipilimumab plus dacarbazine for previously untreated metastatic melanoma
-
Robert C, Thomas L, Bondarenko I et al. Ipilimumab plus dacarbazine for previously untreated metastatic melanoma. N. Engl. J. Med. 364(26), 2517-2526 (2011).
-
(2011)
N. Engl. J. Med.
, vol.364
, Issue.26
, pp. 2517-2526
-
-
Robert, C.1
Thomas, L.2
Bondarenko, I.3
-
5
-
-
84879759020
-
Safety and tumor responses with lambrolizumab (anti-PD-1) in melanoma
-
Hamid O, Robert C, Daud A et al. Safety and tumor responses with lambrolizumab (anti-PD-1) in melanoma. N. Engl. J. Med. 369(2), 134-144 (2013).
-
(2013)
N. Engl. J. Med.
, vol.369
, Issue.2
, pp. 134-144
-
-
Hamid, O.1
Robert, C.2
Daud, A.3
-
6
-
-
84929481481
-
Pembrolizumab versus ipilimumab in advanced melanoma
-
Robert C, Schachter J, Long GV et al. Pembrolizumab versus ipilimumab in advanced melanoma. N. Engl. J. Med. 372(26), 2521-2532 (2015).
-
(2015)
N. Engl. J. Med.
, vol.372
, Issue.26
, pp. 2521-2532
-
-
Robert, C.1
Schachter, J.2
Long, G.V.3
-
7
-
-
84929481480
-
Pembrolizumab for the treatment of non-small-cell lung cancer
-
Garon EB, Rizvi NA, Hui R et al. Pembrolizumab for the treatment of non-small-cell lung cancer. N. Engl. J. Med. 372(21), 2018-2028 (2015).
-
(2015)
N. Engl. J. Med.
, vol.372
, Issue.21
, pp. 2018-2028
-
-
Garon, E.B.1
Rizvi, N.A.2
Hui, R.3
-
8
-
-
49649114804
-
Phase i safety and pharmacokinetic study of ct-011, a humanized antibody interacting with PD-1, in patients with advanced hematologic malignancies
-
Berger R, Rotem-Yehudar R, Slama G et al. Phase I safety and pharmacokinetic study of ct-011, a humanized antibody interacting with PD-1, in patients with advanced hematologic malignancies. Clin. Cancer Res. 14(10), 3044-3051 (2008).
-
(2008)
Clin. Cancer Res.
, vol.14
, Issue.10
, pp. 3044-3051
-
-
Berger, R.1
Rotem-Yehudar, R.2
Slama, G.3
-
9
-
-
84890096527
-
Disabling immune tolerance by programmed death-1 blockade with pidilizumab after autologous hematopoietic stem-cell transplantation for diffuse large B-cell lymphoma: Results of an international Phase II trial
-
Armand P, Nagler A, Weller EA et al. Disabling immune tolerance by programmed death-1 blockade with pidilizumab after autologous hematopoietic stem-cell transplantation for diffuse large B-cell lymphoma: results of an international Phase II trial. J. Clin. Oncol. 31(33), 4199-4206 (2013).
-
(2013)
J. Clin. Oncol.
, vol.31
, Issue.33
, pp. 4199-4206
-
-
Armand, P.1
Nagler, A.2
Weller, E.A.3
-
10
-
-
84962282863
-
Efficacy, safety and predictive biomarker results from a randomized phase II study comparing atezolizumab (MPDL3280A) vs docetaxel in 2L/3L NSCLC (POPLAR)
-
Spira A, Park K, Mazieres J, Vansteenkiste J, Rittmeyer A, Ballinger M. Efficacy, safety and predictive biomarker results from a randomized phase II study comparing atezolizumab (MPDL3280A) vs docetaxel in 2L/3L NSCLC (POPLAR). J. Clin. Oncol. 33 (2015).
-
(2015)
J. Clin. Oncol.
, vol.33
-
-
Spira, A.1
Park, K.2
Mazieres, J.3
Vansteenkiste, J.4
Rittmeyer, A.5
Ballinger, M.6
-
11
-
-
84862903106
-
Safety and activity of anti-PD-l1 antibody in patients with advanced cancer
-
Brahmer JR, Tykodi SS, Chow LQ et al. Safety and activity of anti-PD-l1 antibody in patients with advanced cancer. N. Engl. J. Med. 366(26), 2455-2465 (2012).
-
(2012)
N. Engl. J. Med.
, vol.366
, Issue.26
, pp. 2455-2465
-
-
Brahmer, J.R.1
Tykodi, S.S.2
Chow, L.Q.3
-
12
-
-
84942236061
-
Risk of cutaneous toxicities in patients with solid tumors treated with immune checkpoint inhibitors: A meta-analysis
-
Abdel-Rahman O, Elhalawani H, Fouad M. Risk of cutaneous toxicities in patients with solid tumors treated with immune checkpoint inhibitors: A meta-analysis. Future Oncol. 11(17), 2471-2484 (2015).
-
(2015)
Future Oncol.
, vol.11
, Issue.17
, pp. 2471-2484
-
-
Abdel-Rahman, O.1
Elhalawani, H.2
Fouad, M.3
-
13
-
-
84942294585
-
Risk of elevated transaminases in cancer patients treated with immune checkpoint inhibitors: A meta-analysis
-
Abdel-Rahman O, Elhalawani H, Fouad M. Risk of elevated transaminases in cancer patients treated with immune checkpoint inhibitors: A meta-analysis. Expert Opin. Drug Saf. 14(10), 1507-1518 (2015).
-
(2015)
Expert Opin. Drug Saf.
, vol.14
, Issue.10
, pp. 1507-1518
-
-
Abdel-Rahman, O.1
Elhalawani, H.2
Fouad, M.3
-
14
-
-
84963946266
-
Risk of endocrine complications in cancer patients treated with immune check point inhibitors; A meta-analysis
-
Abdel-Rahman O, El Halawani H, Fouad M. Risk of endocrine complications in cancer patients treated with immune check point inhibitors; a meta-analysis. Future Oncol. (2015).
-
(2015)
Future Oncol.
-
-
Abdel-Rahman, O.1
El Halawani, H.2
Fouad, M.3
-
15
-
-
84948171577
-
Risk of gastrointestinal complications in cancer patients treated with immune checkpoint inhibitors; A meta-analysis
-
Abdel-Rahman O, ElHalawani H. , Fouad M. Risk of gastrointestinal complications in cancer patients treated with immune checkpoint inhibitors; a meta-analysis. Immunotherapy 7(11), 1213-1227 (2015).
-
(2015)
Immunotherapy
, vol.7
, Issue.11
, pp. 1213-1227
-
-
Abdel-Rahman, O.1
ElHalawani, H.2
Fouad, M.3
-
16
-
-
84891373595
-
Safety and activity of PD1 blockade by pidilizumab in combination with rituximab in patients with relapsed follicular lymphoma: A single group, open-label, Phase 2 trial
-
Westin JR, Chu F, Zhang M et al. Safety and activity of PD1 blockade by pidilizumab in combination with rituximab in patients with relapsed follicular lymphoma: A single group, open-label, Phase 2 trial. Lancet Oncol. 15(1), 69-77 (2014).
-
(2014)
Lancet Oncol.
, vol.15
, Issue.1
, pp. 69-77
-
-
Westin, J.R.1
Chu, F.2
Zhang, M.3
-
17
-
-
84876248304
-
Endocrine side effects induced by immune checkpoint inhibitors
-
Corsello SM, Barnabei A, Marchetti P, De Vecchis L, Salvatori R, Torino F. Endocrine side effects induced by immune checkpoint inhibitors. J. Clin. Endocrinol. Metab. 98(4), 1361-1375 (2013).
-
(2013)
J. Clin. Endocrinol. Metab.
, vol.98
, Issue.4
, pp. 1361-1375
-
-
Corsello, S.M.1
Barnabei, A.2
Marchetti, P.3
De Vecchis, L.4
Salvatori, R.5
Torino, F.6
-
18
-
-
84888226962
-
Endocrine side-effects of anti-cancer drugs: MAbs and pituitary dysfunction: Clinical evidence and pathogenic hypotheses
-
Torino F, Barnabei A, Paragliola RM, Marchetti P, Salvatori R, Corsello SM. Endocrine side-effects of anti-cancer drugs: mAbs and pituitary dysfunction: clinical evidence and pathogenic hypotheses. Eur. J. Endocrinol. 169(6), R153-R164 (2013).
-
(2013)
Eur. J. Endocrinol.
, vol.169
, Issue.6
, pp. R153-R164
-
-
Torino, F.1
Barnabei, A.2
Paragliola, R.M.3
Marchetti, P.4
Salvatori, R.5
Corsello, S.M.6
-
19
-
-
69149107165
-
Preferred reporting items for systematic reviews and meta-analyses: The prisma statement
-
Moher D, Liberati A, Tetzlaff J, Altman DG. Preferred reporting items for systematic reviews and meta-analyses: the prisma statement. Ann. Intern. Med. 151(4), 264-269 (2009).
-
(2009)
Ann. Intern. Med.
, vol.151
, Issue.4
, pp. 264-269
-
-
Moher, D.1
Liberati, A.2
Tetzlaff, J.3
Altman, D.G.4
-
20
-
-
0029914622
-
Assessing the quality of reports of randomized clinical trials: Is blinding necessary?
-
Jadad AR, Moore RA, Carroll D et al. Assessing the quality of reports of randomized clinical trials: is blinding necessary? Control. Clin. Trials 17(1), 1-12 (1996).
-
(1996)
Control. Clin. Trials
, vol.17
, Issue.1
, pp. 1-12
-
-
Jadad, A.R.1
Moore, R.A.2
Carroll, D.3
-
21
-
-
26944454062
-
Simultaneous comparison of multiple treatments: Combining direct and indirect evidence
-
Caldwell DM, Ades A, Higgins J. Simultaneous comparison of multiple treatments: combining direct and indirect evidence. Br. Med. J. 331(7521), 897 (2005).
-
(2005)
Br. Med. J.
, vol.331
, Issue.7521
, pp. 897
-
-
Caldwell, D.M.1
Ades, A.2
Higgins, J.3
-
22
-
-
5044221416
-
Combination of direct and indirect evidence in mixed treatment comparisons
-
Lu G, Ades A. Combination of direct and indirect evidence in mixed treatment comparisons. Stat. Med. 23(20), 3105-3124 (2004).
-
(2004)
Stat. Med.
, vol.23
, Issue.20
, pp. 3105-3124
-
-
Lu, G.1
Ades, A.2
-
23
-
-
84936791837
-
Nivolumab versus docetaxel in advanced squamous cell non-small-cell lung cancer
-
Brahmer J, Reckamp KL, Baas P et al. Nivolumab versus docetaxel in advanced squamous cell non-small-cell lung cancer. N. Engl. J. Med. (2015).
-
(2015)
N. Engl. J. Med.
-
-
Brahmer, J.1
Reckamp, K.L.2
Baas, P.3
-
24
-
-
84925222119
-
Nivolumab in previously untreated melanoma without braf mutation
-
Robert C, Long GV, Brady B et al. Nivolumab in previously untreated melanoma without braf mutation. N. Engl. J. Med. 372(4), 320-330 (2015).
-
(2015)
N. Engl. J. Med.
, vol.372
, Issue.4
, pp. 320-330
-
-
Robert, C.1
Long, G.V.2
Brady, B.3
-
25
-
-
84931083080
-
Nivolumab versus chemotherapy in patients with advanced melanoma who progressed after anti-CTLA-4 treatment (checkmate 037): A randomised, controlled, open-label, Phase 3 trial
-
Weber JS, D'angelo SP, Minor D et al. Nivolumab versus chemotherapy in patients with advanced melanoma who progressed after anti-CTLA-4 treatment (checkmate 037): A randomised, controlled, open-label, Phase 3 trial. Lancet Oncol. 16(4), 375-384 (2015).
-
(2015)
Lancet Oncol.
, vol.16
, Issue.4
, pp. 375-384
-
-
Weber, J.S.1
D'Angelo, S.P.2
Minor, D.3
-
26
-
-
84944937210
-
Nivolumab versus docetaxel in advanced nonsquamous non-small-cell lung cancer
-
Borghaei H, Paz-Ares L, Horn L et al. Nivolumab versus docetaxel in advanced nonsquamous non-small-cell lung cancer. N. Engl. J. Med. 373(17), 1627-1639 (2015).
-
(2015)
N. Engl. J. Med.
, vol.373
, Issue.17
, pp. 1627-1639
-
-
Borghaei, H.1
Paz-Ares, L.2
Horn, L.3
-
27
-
-
84938205998
-
Pembrolizumab versus investigator-choice chemotherapy for ipilimumab-refractory melanoma (keynote-002): A randomised, controlled, Phase 2 trial
-
Ribas A, Puzanov I, Dummer R et al. Pembrolizumab versus investigator-choice chemotherapy for ipilimumab-refractory melanoma (keynote-002): A randomised, controlled, Phase 2 trial. Lancet Oncol. 16(8 ), 908-918 (2015).
-
(2015)
Lancet Oncol.
, vol.16
, Issue.8
, pp. 908-918
-
-
Ribas, A.1
Puzanov, I.2
Dummer, R.3
-
28
-
-
84929481482
-
Nivolumab and ipilimumab versus ipilimumab in untreated melanoma
-
Postow MA, Chesney J, Pavlick AC et al. Nivolumab and ipilimumab versus ipilimumab in untreated melanoma. N. Engl. J. Med. 372(21), 2006-2017 (2015).
-
(2015)
N. Engl. J. Med.
, vol.372
, Issue.21
, pp. 2006-2017
-
-
Postow, M.A.1
Chesney, J.2
Pavlick, A.C.3
-
29
-
-
84936147067
-
Combined nivolumab and ipilimumab or monotherapy in untreated melanoma
-
Larkin J, Chiarion-Sileni V, Gonzalez R et al. Combined nivolumab and ipilimumab or monotherapy in untreated melanoma. N. Engl. J. Med. 373(1), 23-34 (2015).
-
(2015)
N. Engl. J. Med.
, vol.373
, Issue.1
, pp. 23-34
-
-
Larkin, J.1
Chiarion-Sileni, V.2
Gonzalez, R.3
-
30
-
-
84952638752
-
Immune checkpoints aberrations and gastric cancer; Assessment of prognostic value and evaluation of therapeutic potentials
-
Abdel-Rahman O. Immune checkpoints aberrations and gastric cancer; assessment of prognostic value and evaluation of therapeutic potentials. Crit. Rev. Oncol. Hematol. (2015).
-
(2015)
Crit. Rev. Oncol. Hematol.
-
-
Abdel-Rahman, O.1
-
31
-
-
84879579673
-
At the bench: Preclinical rationale for CTLA-4 and PD-1 blockade as cancer immunotherapy
-
Intlekofer AM, Thompson CB. At the bench: preclinical rationale for CTLA-4 and PD-1 blockade as cancer immunotherapy. J. Leukoc. Biol. 94(1), 25-39 (2013).
-
(2013)
J. Leukoc. Biol.
, vol.94
, Issue.1
, pp. 25-39
-
-
Intlekofer, A.M.1
Thompson, C.B.2
-
32
-
-
0030443168
-
Regulation of surface and intracellular expression of CTLA4 on mouse T cells
-
Alegre M-L, Noel PJ, Eisfelder BJ et al. Regulation of surface and intracellular expression of CTLA4 on mouse T cells. J. Immunol. 157(11), 4762-4770 (1996).
-
(1996)
J. Immunol.
, vol.157
, Issue.11
, pp. 4762-4770
-
-
Alegre, M.-L.1
Noel, P.J.2
Eisfelder, B.J.3
-
33
-
-
84862859820
-
Safety, activity, and immune correlates of anti-PD-1 antibody in cancer
-
Topalian SL, Hodi FS, Brahmer JR et al. Safety, activity, and immune correlates of anti-PD-1 antibody in cancer. N. Engl. J. Med. 366(26), 2443-2454 (2012).
-
(2012)
N. Engl. J. Med.
, vol.366
, Issue.26
, pp. 2443-2454
-
-
Topalian, S.L.1
Hodi, F.S.2
Brahmer, J.R.3
-
34
-
-
84904553412
-
Kidney injuries related to ipilimumab
-
Izzedine H, Gueutin V, Gharbi C et al. Kidney injuries related to ipilimumab. Invest. New Drugs 32(4), 769-773 (2014).
-
(2014)
Invest. New Drugs
, vol.32
, Issue.4
, pp. 769-773
-
-
Izzedine, H.1
Gueutin, V.2
Gharbi, C.3
-
35
-
-
67650491041
-
Anti-ctla4 antibody-induced lupus nephritis
-
Fadel F, Karoui KE, Knebelmann B. Anti-ctla4 antibody-induced lupus nephritis. N. Engl. J. Med. 361(2), 211-212 (2009).
-
(2009)
N. Engl. J. Med.
, vol.361
, Issue.2
, pp. 211-212
-
-
Fadel, F.1
Karoui, K.E.2
Knebelmann, B.3
-
36
-
-
84940658390
-
Proteinuria in patients with solid tumors treated with ramucirumab: A systematic review and meta-analysis
-
Abdel-Rahman O, Elhalawani H. Proteinuria in patients with solid tumors treated with ramucirumab: A systematic review and meta-analysis. Chemotherapy 60(5-6), 325-333 (2014).
-
(2014)
Chemotherapy
, vol.60
, Issue.5-6
, pp. 325-333
-
-
Abdel-Rahman, O.1
Elhalawani, H.2
-
37
-
-
84864052441
-
Management of immune-related adverse events and kinetics of response with ipilimumab
-
Weber JS, Kähler KC, Hauschild A. Management of immune-related adverse events and kinetics of response with ipilimumab. J. Clin. Oncol. 30(21), 2691-2697 (2012).
-
(2012)
J. Clin. Oncol.
, vol.30
, Issue.21
, pp. 2691-2697
-
-
Weber, J.S.1
Kähler, K.C.2
Hauschild, A.3
-
38
-
-
84929508057
-
Ipilimumab granulomatous interstitial nephritis
-
Thajudeen B, Madhrira M, Bracamonte E, Cranmer LD. Ipilimumab granulomatous interstitial nephritis. Am. J. Ther. 22(3), e84-e87 (2015).
-
(2015)
Am. J. Ther.
, vol.22
, Issue.3
, pp. e84-e87
-
-
Thajudeen, B.1
Madhrira, M.2
Bracamonte, E.3
Cranmer, L.D.4
-
39
-
-
84946607195
-
Nivolumab versus everolimus in advanced renal-cell carcinoma
-
Motzer RJ, Escudier B, Mcdermott DF et al. Nivolumab versus everolimus in advanced renal-cell carcinoma. N. Engl. J. Med. 373(19), 1803-1813 (2015).
-
(2015)
N. Engl. J. Med.
, vol.373
, Issue.19
, pp. 1803-1813
-
-
Motzer, R.J.1
Escudier, B.2
Mcdermott, D.F.3
-
40
-
-
82455194995
-
Radiologic manifestations of immune-related adverse events in patients with metastatic melanoma undergoing anti-CTLA-4 antibody therapy
-
Bronstein Y, Ng CS, Hwu P, Hwu W-J. Radiologic manifestations of immune-related adverse events in patients with metastatic melanoma undergoing anti-CTLA-4 antibody therapy. AJR Am. J. Roentgenol. 197(6), W992-W1000 (2011).
-
(2011)
AJR Am. J. Roentgenol.
, vol.197
, Issue.6
, pp. W992-W1000
-
-
Bronstein, Y.1
Ng, C.S.2
Hwu, P.3
Hwu, W.-J.4
|