Comparison of a Broad Spectrum Anti-Aging Nutritional Supplement with and without the Addition of a DNA Repair Enhancing Cat's Claw Extract

Journal of Anti-Aging Medicine

Volumn 5, Issue 4, 2002, Pages 345-353

  Pero, Ronald W ^a   Giampapa, Vincent ^b   Vojdani, Aristo ^c  

^a LUND UNIVERSITY   (Sweden)

^b Immunosciences Lab Inc ^*  (United States)

^c Immunosciences Laboratories Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84968460519     PISSN: 10945458     EISSN: None     Source Type: Journal    
DOI: 10.1089/109454502763485467     Document Type: Article

References (18)

1. Hendler S. S., ed. The doctor's vitamin and mineral encyclopedia. New York: Simon and Schuster, 1991.
2. Cross C. E., Halliwell B., Borisch E. T., et al. Oxygen radicals and human disease. Ann Intern Med 1987;107: 526–545.
3. Baker H., DeAngelis B., Baker E., et al. Human plasma patterns during 14 days ingestion of vitamin E, beta carotene, ascorbic acid, and other various combinations. J Am Clin Nutr 1996;15:159–163.
4. Kubena K. S., McMurray D. N. Nutrition and the immune system. A review of nutrient-nutrient interactions. J Am Diet Assoc 1996;96:1156–1164.
5. Niki E., Noguchi N., Tsuchihashi H., et al. Interaction among vitamin C, vitamin E and beta carotene. Am J Clin Nutr 1995;62(suppl):1322S-1326S.
6. Cerutti P. Prooxidant states and tumor promotion. Science 1985;227:375–381.
7. Pero R. W., Olsson A., Sheng Y. et al. Progress in identifiying clinical relevance of inhibition, stimulation and measurement of poly ADP-ribosylation. Biochimie 1995;77:385–393.
8. Lamm S., Sheng Y., Pero R. W. Persistent response to pneumococcal vaccine in individuals supplemented with a novel water-soluble extract of Uncaria tomentosa, C-Med-100. Phytomedicine 2001;8:267–274.
9. Sandoval M., Charbonnet R. M., Okuhama N. N., et al. Cat's claw inhibits TNFalpha production and scavenger radicals: role in cytoprotection. Free Radic Biol Med 2000;29:71–78.
10. Sandoval-Chancon M., Thompson J. H., Zhang X. J., et al. Antiinflammatory actions of cat's claw: the role of NF-kB. Aliment Pharmacol Ther 1998;12:1279–1289.
11. Sheng Y., Pero R. W., Amiri A., et al. Induction of apoptosis and inhibition of proliferation in human tumor cells treated with extracts of Uncaria tomentosa. Anti-cancer Res 1998;18:3363–3368.
12. Sheng Y., Pero R. W., Olsson A. R., et al. DNA repair enhancement by combined supplement of carotenoids, nicotinamide, and zinc. Cancer Det Prevent 1998;22: 284–292.
13. Sheng Y., Bryngelsson C., Pero R. W. Enhanced DNA repair, immune function and reduced toxicity of C. Med-100, a novel aqueous extract from Uncaria tomentosa. J Ethanophamacol 2000;69:115–126.
14. Sheng Y., Pero R. W., Wagner H. Treatment of chemotherapy-induced leukopenia in a rat model with aqueous extract from Uncaria tomentosa. Phytomedicine 2000;7:137–143.
15. Sheng Y., Li L., Holmgren K., et al. DNA repair enhancement of aqueous extracts of Uncaria tomentosa in a human volunteer study. Phytomedicine 2001;8:275–282.
16. Park J. W., Cundy K. C., Ames B. N. Detection of DNA adducts by high pressure chromatography with electrochemical detection. Carcinogenesis 1989;10: 827–835.
17. Pero R. W., Hoppe C., Sheng Y. Serum thiols as a surrogate estimate of DNA repair correlates to mammalian life span. J Anti-Aging Med 2000;3:241–249.
18. Lieber M. R. Warner-Lambert/Parke Davis Award Lecture: pathological and physiological double-stranded breaks. Roles in cancer, aging and the immune system. Am J Pathol 1998;153:1323–1332.