Serpins in a lepidopteran insect, Manduca sexta

Molecular and Cellular Aspects of the Serpinopathies and Disorders in Serpin Activity

Volumn , Issue , 2007, Pages 229-241

  Kanost, Michael R ^a  

^a KANSAS STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84967679621     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1142/9789812707543_0009     Document Type: Chapter

References (56)

1. Kanost MR (1999) Serine proteinase inhibitors in arthropod immunity. Dev Comp Immunol 23(4-5):291-301.
2. Polanowski A, Wilusz T, Blum MS, Escoubas P, Schmidt JO and Travis J (1992) Serine proteinase inhibitor profiles in the hemolymph of a wide range of insect species. Comp Biochem Physiol B 102(4):757-760.
3. Polanowski A and Wilusz T (1996) Serine proteinase inhibitors from insect hemolymph. Acta Biochim Pol 43(3):445-453.
4. Sasaki T, Kobayashi K and Ozeki T (1987) Interaction of silkworm larval hemolymph antitrypsin and bovine trypsin. J Biochem (Tokyo)102(2):433-441.
5. Sasaki T, Kohara A, Shimidzu T and Kobayashi, K (1990) Single site proteolysis in silkworm antitrypsin causes structural changes in behavior against denaturing reagents. Agric Biol Chem 54(1):139-145.
6. Sasaki T, Kohara A, Takagi H and Shimidzu T (1990) Limited proteolysis of silkworm antitrypsin by several proteinases. Agric Biol Chem 54(1):131-137.
7. Sasaki T (1985) The reactive site of silkworm hemolymph antichymotrypsin is located at the COOH-terminal region of the molecule. Biochem Biophys Res Commun 132 (1):320-326.
8. Kanost MR, Prasad SV andWells MA (1989) Primary structure of a member of the serpin superfamily of proteinase inhibitors from an insect, Manduca sexta. J Biol Chem 264(2):965-972.
9. Kanost MR(1990) Isolation and characterization of four serine proteinase inhibitors (serpins) from hemolymph of Manduca sexta. Insect Biochem 20:141-147.
10. Sasaki T (1991) Patchwork-structure serpins from silkworm (Bombyx mori) larval hemolymph. Eur J Biochem 202(2):255-261.
11. Narumi H, Hishida T, Sasaki T, Feng DF and Doolittle RF (1993) Molecular cloning of silkworm (Bombyx mori antichymotrypsin. A new member of the serpin superfamily of proteins from insects. Eur J Biochem 214(1):181-187.
12. Irving JA, Pike RN, Lesk AM and Whisstock JC (2000) Phylogeny of the serpin superfamily: Implications of patterns of amino acid conservation for structure and function. Genome Res 10(12):1845-1864.
13. Silverman GA, Bird PI, Carrell RWet al. (2001) The serpins are an expanding superfamily of structurally similar but functionally diverse proteins. Evolution, mechanism of inhibition, novel functions, and a revised nomenclature. J Biol Chem 276(36):33293-33296.
14. Kanost MR and Jiang H(1997) Serpins from an insect, Manduca sexta. Adv Exp Med Biol 425:155-161.
15. Kanost MR, Jiang H and Yu(2004) XQ Innate immune responses of a lepidopteran insect, Manduca sexta. Immunol Rev 198:97-105.
16. Tong Y, Jiang H and Kanost MR (2005) Identification of plasma proteases inhibited by Manduca sexta serpin-4 and serpin-5 and their association with components of the prophenol oxidase activation pathway. J Biol Chem 280(15):14932-14942.
17. Tong Y and Kanost MR (2005) Manduca sexta serpin-4 and serpin-5 inhibit the prophenol oxidase activation pathway: cDNA cloning, protein expression, and characterization. J Biol Chem 280(15):14923-14931.
18. Jiang H, Wang Y and Kanost MR (1994) Mutually exclusive exon use and reactive center diversity in insect serpins. J Biol Chem 269(1):55-58.
19. Jiang H, Wang Y, Huang Y et al. (1996) Organization of serpin gene-1 from Manduca sexta. Evolution of a family of alternate exons encoding the reactive site loop. J Biol Chem 271(45):28017-28023.
20. Li J, Wang Z, Canagarajah B, Jiang H, Kanost M and Goldsmith EJ (1999) The structure of active serpin 1K from Manduca sexta. Struct Fold Des 7(1):103-109.
21. Ye S, Cech AL, Belmares R et al. (2001) The structure of a Michaelis serpinprotease complex. Nat Struct Biol 8(11):979-983.
22. Jiang H and Kanost MR (1997) Characterization and functional analysis of 12 naturally occurring reactive site variants of serpin-1 from Manduca sexta. J Biol Chem 272(2):1082-1087.
23. Kanost MR, Prasad SV, Huang Y and Willott E (1995) Regulation of serpin gene-1 in Manduca sexta. Insect Biochem Mol Biol 25(2):285-291.
24. Chamankhah M, Braun L, Visal-Shah S et al. (2003) Mamestra configurata serpin-1 homologues: Cloning, localization and developmental regulation. Insect Biochem Mol Biol 33(3):355-369.
25. Kruger O, Ladewig J, Koster K and Ragg H(2002)Widespread occurrence of serpin genes with multiple reactive centre-containing exon cassettes in insects and nematodes. Gene 293(1-2):97-105.
26. Danielli A, Kafatos FC and Loukeris TG (2003) Cloning and characterization of four Anopheles gambiae serpin isoforms, differentially induced in the midgut by Plasmodium berghei invasion. J Biol Chem 278(6):4184-4193.
27. Jiang H, MulnixABand KanostMR(1995) Expression and characterization of recombinant Manduca sexta serpin-1B and site-directed mutants that change its inhibitory selectivity. Insect Biochem Mol Biol 25(10):1093-1100.
28. Ye S and Goldsmith EJ (2001) Serpins and other covalent protease inhibitors. Curr Opin Struct Biol 11(6):740-745.
29. Gettins PG (2002) Serpin structure, mechanism, and function. Chem Rev 102(12):4751-4804.
30. Gan H,WangY, Jiang H, Mita K and Kanost MR (2001) A bacteria-induced, intracellular serpin in granular hemocytes of Manduca sexta. Insect Biochem Mol Biol 31(9):887-898.
31. Jiang H, WangY and Kanost MR (1999) Four serine proteinases expressed in Manduca sexta haemocytes. Insect Mol Biol 8(1):39-53.
32. Jiang H, Wang Y, Gu Y et al. (2005) Molecular identification of a bevy of serine proteinases in Manduca sexta hemolymph. Insect Biochem Mol Biol 35(8):931-943.
33. Silverman GA, Whisstock JC, Askew DJ et al. (2004) Human clade B serpins (ov-serpins) belong to a cohort of evolutionarily dispersed intracellular proteinase inhibitor clades that protect cells from promiscuous proteolysis. Cell Mol Life Sci 61(3):301-325.
34. Zhu Y, Wang Y, Gorman MJ, Jiang H and Kanost MR (2003) Manduca sexta serpin-3 regulates prophenoloxidase activation in response to infection by inhibiting prophenoloxidase-activating proteinases. J Biol Chem 278(47):46556-46564.
35. Park DS, Shin SW, Hong SD and Park HY (2000) Immunological detection of serpin in the fall webworm, Hyphantria cunea and its inhibitory activity on the prophenoloxidase system. Mol Cells 10(2):186-192.
36. De Gregorio E, Han SJ, Lee WJ et al. (2002) An immune-responsive Serpin regulates the melanization cascade in Drosophila. Dev Cell 3(4):581-592.
37. Ligoxygakis P, Pelte N, Ji C et al. (2002) A serpin mutant links Toll activation to melanization in the host defence of Drosophila. Embo J 21(23):6330-6337.
38. Wang Y and Jiang H (2004) Purification and characterization of Manduca sexta serpin-6: A serine proteinase inhibitor that selectively inhibits prophenoloxidase-activating proteinase-3. Insect Biochem Mol Biol 34(4):387-395.
39. Zou Z and Jiang H (2005) Manduca sexta serpin-6 regulates immune serine proteinases PAP-3 and HP8. cDNA cloning, protein expression, inhibition kinetics, and function elucidation. J Biol Chem 280(14):14341-14348.
40. Adams MD, Celniker SE, Holt RA et al. (2000) The genome sequence of Drosophila melanogaster. Science 287(5461):2185-2195.
41. Ross J, Jiang H, Kanost MR and Wang Y(2003) Serine proteases and their homologs in the Drosophila melanogaster genome: An initial analysis of sequence conservation and phylogenetic relationships. Gene 304:117-131.
42. Christophides GK, ZdobnovE, Barillas-MuryCet al. (2002) Immunity-related genes and gene families in Anopheles gambiae. Science 298(5591):159-165.
43. Kanost M and Clarke T(2005) Proteases, in L Gilbert, K Iatrou and S Gill (eds.), Comprehensive Molecular Insect Science. Elsevier, New York, pp. 247-266.
44. Iwanaga S (2002) The molecular basis of innate immunity in the horseshoe crab. Curr Opin Immunol 14(1):87-95.
45. Cerenius L and Soderhall K(2004) The prophenoloxidase-activating system in invertebrates. Immunol Rev 198:116-126.
46. Yu X-Q Prakash O and Kanost MR(2001) Insect ENF family peptides with diverse biological activities display similar core structures in solution. Medicinal Chem Res 10:493-501.
47. Ferrandon D, Imler JL and Hoffmann JA (2004) Sensing infection in Drosophila: Toll and beyond. Semin Immunol 16(1):43-53.
48. Jiang H, Wang Y and Kanost MR (1998) Pro-phenol oxidase activating proteinase from an insect, Manduca sexta:A bacteria-inducible protein similar to Drosophila easter. Proc Natl Acad Sci USA 95(21):12220-12225.
49. Jiang H,WangY, Yu XQ and Kanost MR (2003) Prophenoloxidase-activating proteinase-2 from hemolymph of Manduca sexta. A bacteria-inducible serine proteinase containing two clip domains. J Biol Chem 278(6):3552-3561.
50. Jiang H, Wang Y, Yu XQ, Zhu Y and Kanost M (2003) Prophenoloxidaseactivating proteinase-3 (PAP-3) from Manduca sexta hemolymph: A clipdomain serine proteinase regulated by serpin-1J and serine proteinase homologs. Insect Biochem Mol Biol 33(10):1049-1060.
51. Yu XQ, Jiang H, Wang Y and Kanost MR (2003) Nonproteolytic serine proteinase homologs are involved in prophenoloxidase activation in the tobacco hornworm, Manduca sexta. Insect Biochem Mol Biol 33(2):197-208.
52. Gupta S, Wang Y and Jiang H(2005) Manduca sexta prophenoloxidase (proPO) activation requires proPO-activating proteinase (PAP) and serine proteinase homologs (SPHs) simultaneously. Insect Biochem Mol Biol 35:241-248.
53. Jiang H and Kanost MR (2000) The clip-domain family of serine proteinases in arthropods. Insect Biochem Mol Biol 30(2):95-105.
54. Hashimoto C, Kim DR, Weiss LA, Miller JW and Morisato D (2003) Spatial regulation of developmental signaling by a serpin. Dev Cell 5(6):945-950.
55. Ligoxygakis P, Roth S and Reichhart JM (2003) A serpin regulates dorsalventral axis formation in the Drosophila embryo. Curr Biol 13(23):2097-2102.
56. Ligoxygakis P, Pelte N, Hoffmann JA and Reichhart JM (2002) Activation of Drosophila toll during fungal infection by a blood serine protease. Science 297(5578):114-116.