메뉴 건너뛰기




Volumn 54, Issue 11, 2016, Pages 2521-2527

Myrtenal alleviates hyperglycaemia, hyperlipidaemia and improves pancreatic insulin level in STZ-induced diabetic rats

Author keywords

Antihyperglycaemic; antihyperlipidaemic; atherogenic index; histopathology

Indexed keywords

CHOLESTEROL; FATTY ACID; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; INSULIN; LIPOPROTEIN LIPASE; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MYRTENAL; PHOSPHATIDYLCHOLINE STEROL ACYLTRANSFERASE; TERPENE DERIVATIVE; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; VERY LOW DENSITY LIPOPROTEIN CHOLESTEROL; STREPTOZOCIN; TERPENE;

EID: 84966714530     PISSN: 13880209     EISSN: 17445116     Source Type: Journal    
DOI: 10.3109/13880209.2016.1168852     Document Type: Article
Times cited : (20)

References (48)
  • 1
    • 0023880042 scopus 로고
    • High density lipoprotein cholesterol, total cholesterol screening, and myocardial infarction. The Framingham Study
    • R.D.Abbott, P.W.Wilson, W.B.Kannel, W.P.Castelli 1988. High density lipoprotein cholesterol, total cholesterol screening, and myocardial infarction. The Framingham Study. Arteriosclerosis. 8:207–211.
    • (1988) Arteriosclerosis , vol.8 , pp. 207-211
    • Abbott, R.D.1    Wilson, P.W.2    Kannel, W.B.3    Castelli, W.P.4
  • 4
    • 0028037942 scopus 로고
    • Hypoglycaemic effect of Artemisia herba alba. II. Effect of a valuable extract on some blood parameters in diabetic animals
    • L.Al-Shamaony, S.M.Al-Khazraji, H.A.Twaij 1994. Hypoglycaemic effect of Artemisia herba alba. II. Effect of a valuable extract on some blood parameters in diabetic animals. J Ethnopharmacol. 43:167–171.
    • (1994) J Ethnopharmacol , vol.43 , pp. 167-171
    • Al-Shamaony, L.1    Al-Khazraji, S.M.2    Twaij, H.A.3
  • 5
    • 84865659623 scopus 로고    scopus 로고
    • Myrtenal, a natural monoterpene, down-regulates TNF-α expression and suppresses carcinogen-induced hepatocellular carcinoma in rats
    • L.H.Babu, S.Perumal, M.P.Balasubramanian 2012. Myrtenal, a natural monoterpene, down-regulates TNF-α expression and suppresses carcinogen-induced hepatocellular carcinoma in rats. Mol Cell Biochem. 369:183–193.
    • (2012) Mol Cell Biochem , vol.369 , pp. 183-193
    • Babu, L.H.1    Perumal, S.2    Balasubramanian, M.P.3
  • 7
    • 0346880515 scopus 로고    scopus 로고
    • Alterations in high-density lipoprotein metabolism and reverse cholesterol transport in insulin resistance and type 2 diabetes mellitus: role of lipolytic enzymes, lecithin: cholesterol acyltransferase and lipid transfer proteins
    • S.E.Borggreve, R.DeVries, R.P.F.Dullaart 2003. Alterations in high-density lipoprotein metabolism and reverse cholesterol transport in insulin resistance and type 2 diabetes mellitus:role of lipolytic enzymes, lecithin:cholesterol acyltransferase and lipid transfer proteins. Eur J Clin Invest. 33:1051–1069.
    • (2003) Eur J Clin Invest , vol.33 , pp. 1051-1069
    • Borggreve, S.E.1    DeVries, R.2    Dullaart, R.P.F.3
  • 9
    • 27644544883 scopus 로고    scopus 로고
    • Lipid and lipoprotein metabolism
    • Baltimore: Williams and Wilkins Publishers
    • R.M.Cohn, K.S.Roth 1996. Lipid and lipoprotein metabolism. Biochemistry and disease. Baltimore:Williams and Wilkins Publishers.
    • (1996) Biochemistry and disease
    • Cohn, R.M.1    Roth, K.S.2
  • 10
    • 84855161758 scopus 로고    scopus 로고
    • Linalool, a plant derived monoterpene alcohol, rescues kidney from diabetes induced nephropathic changes via blood glucose reduction
    • B.Deepa, C.V.Anuradha 2011. Linalool, a plant derived monoterpene alcohol, rescues kidney from diabetes induced nephropathic changes via blood glucose reduction. Diabetol Croat. 40–44.
    • (2011) Diabetol Croat , pp. 40-44
    • Deepa, B.1    Anuradha, C.V.2
  • 11
    • 0033858450 scopus 로고    scopus 로고
    • Metabolic abnormalities of apolipoprotein B-containing lipoproteins in noninsulin-dependent diabetes: a stable isotope kinetic study
    • L.Duvillard, F.Pont, E.Florentin, C.Galland-Jos, P.Gambert, B.Vergès 2000. Metabolic abnormalities of apolipoprotein B-containing lipoproteins in noninsulin-dependent diabetes:a stable isotope kinetic study. Eur J Clin Invest. 30:685–694.
    • (2000) Eur J Clin Invest , vol.30 , pp. 685-694
    • Duvillard, L.1    Pont, F.2    Florentin, E.3    Galland-Jos, C.4    Gambert, P.5    Vergès, B.6
  • 12
    • 84890444690 scopus 로고    scopus 로고
    • Antihyperglycemic effect of carvacrol in combination with rosiglitazone in high-fat diet-induced type 2 diabetic C57BL/6J mice
    • M.Ezhumalai, T.Radhiga, K.V.Pugalendi 2014. Antihyperglycemic effect of carvacrol in combination with rosiglitazone in high-fat diet-induced type 2 diabetic C57BL/6J mice. Mol Cell Biochem. 385:23–31.
    • (2014) Mol Cell Biochem , vol.385 , pp. 23-31
    • Ezhumalai, M.1    Radhiga, T.2    Pugalendi, K.V.3
  • 13
    • 0015849889 scopus 로고
    • An easy colorimetric micro method for routine determination of free fatty acids in plasma
    • K.Falholt, W.Falholt, B.Lund 1973. An easy colorimetric micro method for routine determination of free fatty acids in plasma. Clin Chim Acta. 46:105–111.
    • (1973) Clin Chim Acta , vol.46 , pp. 105-111
    • Falholt, K.1    Falholt, W.2    Lund, B.3
  • 14
    • 70449158340 scopus 로고
    • A simple method for isolation and purification of total lipids from animal tissues
    • J.Folch, M.Lees, S.G.H.Solane 1957. A simple method for isolation and purification of total lipids from animal tissues. J Biol Chem. 26:497–509.
    • (1957) J Biol Chem , vol.26 , pp. 497-509
    • Folch, J.1    Lees, M.2    Solane, S.G.H.3
  • 15
    • 0019949179 scopus 로고
    • Serum triglycerides determined colorimetrically with an enzyme that produces hydrogen peroxide
    • P.Fossati, P.Lorenzo 1982. Serum triglycerides determined colorimetrically with an enzyme that produces hydrogen peroxide. Clin Chem. 28:2077–2080.
    • (1982) Clin Chem , vol.28 , pp. 2077-2080
    • Fossati, P.1    Lorenzo, P.2
  • 16
    • 0027174194 scopus 로고
    • Insulin resistance and lipid metabolism
    • K.N.Frayn 1993. Insulin resistance and lipid metabolism. Curr Opin Lipidol. 4:197–204.
    • (1993) Curr Opin Lipidol , vol.4 , pp. 197-204
    • Frayn, K.N.1
  • 17
    • 0000677439 scopus 로고
    • Estimation of the concentration of LDL-C in plasma without use of the preparative ultracentrifuge
    • W.T.Friedwald, R.I.Levy, D.S.Fredrickson 1972. Estimation of the concentration of LDL-C in plasma without use of the preparative ultracentrifuge. Clin Chem. 18:449–502.
    • (1972) Clin Chem , vol.18 , pp. 449-502
    • Friedwald, W.T.1    Levy, R.I.2    Fredrickson, D.S.3
  • 18
    • 0037317156 scopus 로고    scopus 로고
    • Effects of insulin resistance and type 2 diabetes on lipoprotein subclass particle size and concentration determined by nuclear magnetic resonance
    • W.T.Garvey, S.Kwon, D.Zheng, S.Shaughnessy, P.Wallace, A.Hutto, K.Pugh, A.J.Jenkins, R.L.Klein, Y.Liao 2003. Effects of insulin resistance and type 2 diabetes on lipoprotein subclass particle size and concentration determined by nuclear magnetic resonance. Diabetes. 52:453–462.
    • (2003) Diabetes , vol.52 , pp. 453-462
    • Garvey, W.T.1    Kwon, S.2    Zheng, D.3    Shaughnessy, S.4    Wallace, P.5    Hutto, A.6    Pugh, K.7    Jenkins, A.J.8    Klein, R.L.9    Liao, Y.10
  • 19
    • 0022459307 scopus 로고
    • Effect of differences in glucose tolerance on insulin stability regulate carbohydrate and free fatty acid metabolism in obese individuals
    • A.Golay, Y.D.Chen, G.M.Reaven 1986. Effect of differences in glucose tolerance on insulin stability regulate carbohydrate and free fatty acid metabolism in obese individuals. J Clin Endocrinol Metabol. 86:1081–1088.
    • (1986) J Clin Endocrinol Metabol. 86: , pp. 1081-1088
    • Golay, A.1    Chen, Y.D.2    Reaven, G.M.3
  • 20
    • 0020512689 scopus 로고
    • Plasma lecithin: cholesterol acyltransferase-reference values and effects of xenobiotics
    • J.Hitz, J.Steinmetz, G.Siest 1983. Plasma lecithin:cholesterol acyltransferase-reference values and effects of xenobiotics. Clin Chim Acta. 133:85–96.
    • (1983) Clin Chim Acta , vol.133 , pp. 85-96
    • Hitz, J.1    Steinmetz, J.2    Siest, G.3
  • 21
    • 37849004127 scopus 로고    scopus 로고
    • Hypolipidemic effects of sophora flavescens and its constituents in poloxamer407-induced hyperlipidemic and cholesterol-fed rats
    • H.Kim, D.Jeong, H.Jung, Y.J.Jung, T.Yokozawa, J.S.Choi 2008. Hypolipidemic effects of sophora flavescens and its constituents in poloxamer407-induced hyperlipidemic and cholesterol-fed rats. Biol Pharm Bull. 31:73–78.
    • (2008) Biol Pharm Bull , vol.31 , pp. 73-78
    • Kim, H.1    Jeong, D.2    Jung, H.3    Jung, Y.J.4    Yokozawa, T.5    Choi, J.S.6
  • 22
    • 84873766944 scopus 로고
    • Clearing factor, a heparin-activated lipoprotein lipase. I. Isolation and characterization of the enzyme from normal rat heart
    • E.D.Korn 1955. Clearing factor, a heparin-activated lipoprotein lipase. I. Isolation and characterization of the enzyme from normal rat heart. J Biol Chem. 215:1–26.
    • (1955) J Biol Chem , vol.215 , pp. 1-26
    • Korn, E.D.1
  • 23
    • 80052895192 scopus 로고    scopus 로고
    • Methanolic extract of costusigneus (N.E.Br.) alleviates dyslipidemia in diabetic rats
    • K.Kripa, N.R.Vijayalakshmi, A.Helen 2011. Methanolic extract of costusigneus (N.E.Br.) alleviates dyslipidemia in diabetic rats. Asian J Pharm Clin Res. 4:154–157.
    • (2011) Asian J Pharm Clin Res , vol.4 , pp. 154-157
    • Kripa, K.1    Vijayalakshmi, N.R.2    Helen, A.3
  • 24
    • 0023787276 scopus 로고
    • Effect of dietary protein on cholesterol homeostasis in diabetic rats
    • B.J.Kudchodkar, J.C.Lee, S.M.Lee, N.M.DiMarco, A.G.Lacko 1988. Effect of dietary protein on cholesterol homeostasis in diabetic rats. J Lipid Res. 29:1272–1287.
    • (1988) J Lipid Res , vol.29 , pp. 1272-1287
    • Kudchodkar, B.J.1    Lee, J.C.2    Lee, S.M.3    DiMarco, N.M.4    Lacko, A.G.5
  • 25
    • 84856931839 scopus 로고    scopus 로고
    • Antihyperglycemic and antihyperlipidemic effect of Santalumalbum in streptozotocin induced diabetic rats
    • C.R.Kulkarni, M.M.Joglekar, S.B.Patil, A.U.Arvindekar 2012. Antihyperglycemic and antihyperlipidemic effect of Santalumalbum in streptozotocin induced diabetic rats. Pharm Biol. 50:360–365.
    • (2012) Pharm Biol , vol.50 , pp. 360-365
    • Kulkarni, C.R.1    Joglekar, M.M.2    Patil, S.B.3    Arvindekar, A.U.4
  • 26
    • 0031201332 scopus 로고    scopus 로고
    • Insecticidal activity of monoterpenoids to western corn rootworm (Coleoptera: Chrysomelidae) two-spotted spider mite (Acari: Tetranychidae), and house fly (Diptera: Muscidae)
    • S.Lee, R.Tsao, C.Peterson, J.R.Coats 1997. Insecticidal activity of monoterpenoids to western corn rootworm (Coleoptera:Chrysomelidae) two-spotted spider mite (Acari:Tetranychidae), and house fly (Diptera:Muscidae). J Econ Entomol. 90:883–892.
    • (1997) J Econ Entomol , vol.90 , pp. 883-892
    • Lee, S.1    Tsao, R.2    Peterson, C.3    Coats, J.R.4
  • 27
    • 0031898062 scopus 로고    scopus 로고
    • Evaluation of the preservative properties of Thymus vulgaris essential oil in topically applied formulations under a challenge test
    • L.Manou, L.Bouillard, M.J.Devleeschouwer, A.O.Barel 1998. Evaluation of the preservative properties of Thymus vulgaris essential oil in topically applied formulations under a challenge test. J Appl Microbiol. 84:368–376.
    • (1998) J Appl Microbiol , vol.84 , pp. 368-376
    • Manou, L.1    Bouillard, L.2    Devleeschouwer, M.J.3    Barel, A.O.4
  • 30
    • 0035857020 scopus 로고    scopus 로고
    • New drug targets for type 2 diabetes and metabolic syndrome
    • D.E.Moler 2001. New drug targets for type 2 diabetes and metabolic syndrome. Nature. 414:821–827.
    • (2001) Nature , vol.414 , pp. 821-827
    • Moler, D.E.1
  • 31
    • 60749131994 scopus 로고    scopus 로고
    • Dyslipidemia in type 2 diabetes mellitus
    • A.D.Mooradian 2009. Dyslipidemia in type 2 diabetes mellitus. Nat Clin Pract Endocrinol Metab. 5:150–159.
    • (2009) Nat Clin Pract Endocrinol Metab , vol.5 , pp. 150-159
    • Mooradian, A.D.1
  • 32
    • 84869084649 scopus 로고    scopus 로고
    • Antidiabetic effect of d-limonene, a monoterpene in streptozotocin-induced diabetic rats
    • R.Murali, R.Saravanan 2012. Antidiabetic effect of d-limonene, a monoterpene in streptozotocin-induced diabetic rats. Biomed Prev Nutr. 2:269–275.
    • (2012) Biomed Prev Nutr , vol.2 , pp. 269-275
    • Murali, R.1    Saravanan, R.2
  • 33
    • 0037178848 scopus 로고    scopus 로고
    • Over expression of apolipoprotein B in the heart impedes cardiac triglyceride accumulation and development of cardiac dysfunction in diabetic mice
    • L.B.Nielsen, E.D.Bartels, E.Bollana 2002. Over expression of apolipoprotein B in the heart impedes cardiac triglyceride accumulation and development of cardiac dysfunction in diabetic mice. J Biol Chem. 277:14–20.
    • (2002) J Biol Chem , vol.277 , pp. 14-20
    • Nielsen, L.B.1    Bartels, E.D.2    Bollana, E.3
  • 34
    • 11844289636 scopus 로고    scopus 로고
    • Effects of caffeic acid phenethyl ester on lipid peroxidation and antioxidant enzymes in diabetic rat heart
    • H.Okutan, N.Ozcelik, H.R.Yilmaz, E.Uz. 2005. Effects of caffeic acid phenethyl ester on lipid peroxidation and antioxidant enzymes in diabetic rat heart. Clin Biochem. 38:191–196.
    • (2005) Clin Biochem , vol.38 , pp. 191-196
    • Okutan, H.1    Ozcelik, N.2    Yilmaz, H.R.3    Uz, E.4
  • 36
    • 0018396215 scopus 로고
    • Improved methods for the assay and activation of 3-hydroxy-3-methylglutaryl coenzyme A reductase
    • B.Philipp, D.J.Shapiro 1970. Improved methods for the assay and activation of 3-hydroxy-3-methylglutaryl coenzyme A reductase. J Lipid Res. 20:588–593.
    • (1970) J Lipid Res , vol.20 , pp. 588-593
    • Philipp, B.1    Shapiro, D.J.2
  • 37
    • 78649733688 scopus 로고    scopus 로고
    • Antihyperglycaemic, antilipid peroxidative and antioxidant effects of gallic acid on streptozotocin induced diabetic Wistar rats
    • V.R.Punithavathi, P.S.Prince, R.Kumar, J.Selvakumari 2011. Antihyperglycaemic, antilipid peroxidative and antioxidant effects of gallic acid on streptozotocin induced diabetic Wistar rats. Eur J Pharmacol. 650:465–471.
    • (2011) . Eur J Pharmacol , vol.650 , pp. 465-471
    • Punithavathi, V.R.1    Prince, P.S.2    Kumar, R.3    Selvakumari, J.4
  • 38
    • 84873711490 scopus 로고    scopus 로고
    • Efficacy of asiatic acid, a pentacyclic triterpene on attenuating the key enzymes activities of carbohydrate metabolism in streptozotocin-induced diabetic rats
    • V.Ramachandran, R.Saravanan 2013. Efficacy of asiatic acid, a pentacyclic triterpene on attenuating the key enzymes activities of carbohydrate metabolism in streptozotocin-induced diabetic rats. Phytomedicine. 20:230–236.
    • (2013) Phytomedicine , vol.20 , pp. 230-236
    • Ramachandran, V.1    Saravanan, R.2
  • 39
    • 84912050041 scopus 로고    scopus 로고
    • Histopathological findings of the pancreas, liver, and carbohydrate metabolizing enzymes in STZ-induced diabetic rats improved by administration of myrtenal
    • A.Rathinam, L.Pari, R.Chandramohan, B.A.Sheikh 2014. Histopathological findings of the pancreas, liver, and carbohydrate metabolizing enzymes in STZ-induced diabetic rats improved by administration of myrtenal. J Physiol Biochem. 70:935–946.
    • (2014) J Physiol Biochem , vol.70 , pp. 935-946
    • Rathinam, A.1    Pari, L.2    Chandramohan, R.3    Sheikh, B.A.4
  • 40
    • 23744501476 scopus 로고    scopus 로고
    • Does statin monotherapy address the multiple lipid abnormalities in type 2 diabetes?
    • J.Shepherd 2005. Does statin monotherapy address the multiple lipid abnormalities in type 2 diabetes? Atheroscler Suppl. 6:15–19.
    • (2005) Atheroscler Suppl , vol.6 , pp. 15-19
    • Shepherd, J.1
  • 41
    • 34547858847 scopus 로고    scopus 로고
    • High-density lipoprotein as a therapeutic target: a systematic review
    • I.M.Singh, M.H.Shishehbor, B.J.Ansell 2007. High-density lipoprotein as a therapeutic target:a systematic review. J Am Med Assoc. 298:786–798.
    • (2007) J Am Med Assoc , vol.298 , pp. 786-798
    • Singh, I.M.1    Shishehbor, M.H.2    Ansell, B.J.3
  • 42
    • 16244416215 scopus 로고    scopus 로고
    • Anti-diabetic activity of the semi-purified fractions of Averrhoa bilimbi in high fat diet fed-streptozotocin-induced diabetic rats
    • B.K.Tan, C.H.Tan, P.N.Pushparaj 2005. Anti-diabetic activity of the semi-purified fractions of Averrhoa bilimbi in high fat diet fed-streptozotocin-induced diabetic rats. Life Sci. 76:2827–2839.
    • (2005) Life Sci , vol.76 , pp. 2827-2839
    • Tan, B.K.1    Tan, C.H.2    Pushparaj, P.N.3
  • 43
    • 0023126669 scopus 로고
    • Lipoprotein lipase in diabetes
    • M.R.Taskinen 1987. Lipoprotein lipase in diabetes. Diabetes Metab Rev. 3:551–570.
    • (1987) Diabetes Metab Rev , vol.3 , pp. 551-570
    • Taskinen, M.R.1
  • 44
    • 15744392472 scopus 로고    scopus 로고
    • Metabolic insights into phospholipid function using gene targeted mice
    • J.E.Vance, D.E.Vance 2005. Metabolic insights into phospholipid function using gene targeted mice. J Biol Chem. 280:10877–10880.
    • (2005) J Biol Chem , vol.280 , pp. 10877-10880
    • Vance, J.E.1    Vance, D.E.2
  • 45
    • 70449498069 scopus 로고    scopus 로고
    • Lipid modification in type 2 diabetes: the role of LDL and HDL
    • B.Verges 2009. Lipid modification in type 2 diabetes:the role of LDL and HDL. Fundam Clin Pharmacol. 23:681–685.
    • (2009) Fundam Clin Pharmacol , vol.23 , pp. 681-685
    • Verges, B.1
  • 47
    • 6544234261 scopus 로고
    • Microdetermination of plasma phospholipids by trichloroacetic acid precipitation
    • B.B.Zilversmit, A.K.Davis 1950. Microdetermination of plasma phospholipids by trichloroacetic acid precipitation. J Lab Clin Med. 35:155–160.
    • (1950) J Lab Clin Med , vol.35 , pp. 155-160
    • Zilversmit, B.B.1    Davis, A.K.2
  • 48
    • 50449112322 scopus 로고
    • A simple method for determination of serum cholesterol
    • A.Zlatkis, B.Zak, G.J.Boyle 1953. A simple method for determination of serum cholesterol. J Clin Med Res. 41:486–492.
    • (1953) J Clin Med Res , vol.41 , pp. 486-492
    • Zlatkis, A.1    Zak, B.2    Boyle, G.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.