Vitamin D status during pregnancy and risk of multiple sclerosis in offspring of women in the Finnish Maternity Cohort

JAMA Neurology

Volumn 73, Issue 5, 2016, Pages 515-519

  Munger, Kassandra L ^a   Åivo, Julia ^b   Hongell, Kira ^b   Soilu Hänninen, Merja ^b   Surcel, Heljä Marja ^c   Ascherio, Alberto ^a  

^a HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^b TURKU UNIVERSITY HOSPITAL   (Finland)

^c NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

25 HYDROXYVITAMIN D; CALCIFEDIOL;

ADULT; ARTICLE; ASSAY; CASE CONTROL STUDY; CHEMILUMINESCENCE ASSAY; COHORT ANALYSIS; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; FINLAND; FIRST TRIMESTER PREGNANCY; GESTATIONAL AGE; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTIPLE SCLEROSIS; PRIORITY JOURNAL; PROGENY; PROSPECTIVE STUDY; RISK REDUCTION; SEX; SUMMER; VITAMIN BLOOD LEVEL; VITAMIN D DEFICIENCY; WINTER; ADOLESCENT; BLOOD; PREGNANCY; STATISTICAL MODEL; YOUNG ADULT;

ADOLESCENT; CALCIFEDIOL; CASE-CONTROL STUDIES; COHORT STUDIES; FEMALE; FINLAND; HUMANS; LOGISTIC MODELS; MALE; MULTIPLE SCLEROSIS; PREGNANCY; VITAMIN D DEFICIENCY; YOUNG ADULT;

EID: 84966669923     PISSN: 21686149     EISSN: None     Source Type: Journal    
DOI: 10.1001/jamaneurol.2015.4800     Document Type: Article

References (19)

1. Ascherio A, Munger KL, Lünemann JD. The initiation and prevention of multiple sclerosis. Nat Rev Neurol. 2012;8(11):602-612.
2. Munger KL, Levin LI, Hollis BW, Howard NS, Ascherio A. Serum 25-hydroxyvitamin D levels and risk of multiple sclerosis. JAMA. 2006;296(23): 2832-2838.
3. Salzer J, Hallmans G, Nyström M, Stenlund H, Wadell G, Sundström P. Vitamin D as a protective factor in multiple sclerosis. Neurology. 2012;79(21): 2140-2145.
4. Munger KL, Zhang SM, O'Reilly E, et al. Vitamin D intake and incidence of multiple sclerosis. Neurology. 2004;62(1):60-65.
5. Ueda P, Rafatnia F, Bäärnhielm M, et al. Neonatal vitamin D status and risk of multiple sclerosis. Ann Neurol. 2014;76(3):338-346.
6. Mirzaei F, Michels KB, Munger K, et al. Gestational vitamin D and the risk of multiple sclerosis in offspring. Ann Neurol. 2011;70(1):30-40.
7. Willer CJ, Dyment DA, Sadovnick AD, Rothwell PM, Murray TJ, Ebers GC; Canadian Collaborative Study Group. Timing of birth and risk of multiple sclerosis: population based study. BMJ. 2005;330 (7483):120.
8. Staples J, Ponsonby AL, Lim L. Low maternal exposure to ultraviolet radiation in pregnancy, month of birth, and risk of multiple sclerosis in offspring: longitudinal analysis. BMJ. 2010;340: c1640.
9. Fiddes B, Wason J, Kemppinen A, Ban M, Compston A, Sawcer S. Confounding underlies the apparent month of birth effect in multiple sclerosis. Ann Neurol. 2013;73(6):714-720.
10. Tedeschi R, Luostarinen T, Marus A, et al. No risk of maternal EBV infection for childhood leukemia. Cancer Epidemiol Biomarkers Prev. 2009; 18(10):2790-2792.
11. Holl K, Surcel HM, Koskela P, et al. Maternal Epstein-Barr virus and cytomegalovirus infections and risk of testicular cancer in the offspring: a nested case-control study. APMIS. 2008;116(9): 816-822.
12. Institute of Medicine. Dietary Reference Intakes for Calcium and Vitamin D. Washington, DC: The National Academies Press; 2011.
13. Ascherio A, Munger KL. Not too late to take vitamin D supplements. Ann Neurol. 2014;76(3): 321-322.
14. Shor DB, Barzel J, Tauber E, Amital H. The effects of maternal vitamin D on neonatal growth parameters. Eur J Pediatr. 2015;174(9): 1169-1174.
15. Godang K, Frøslie KF, Henriksen T, Qvigstad E, Bollerslev J. Seasonal variation in maternal and umbilical cord 25(OH) vitamin D and their associations with neonatal adiposity. Eur J Endocrinol. 2014;170(4):609-617.
16. Wuertz C, Gilbert P, Baier W, Kunz C. Cross-sectional study of factors that influence the 25-hydroxyvitamin D status in pregnant women and in cord blood in Germany. Br J Nutr. 2013;110 (10):1895-1902.
17. Mahon P, Harvey N, Crozier S, et al; SWS Study Group. Low maternal vitamin D status and fetal bone development: cohort study. J Bone Miner Res. 2010;25(1):14-19.
18. Ioannou C, Javaid MK, Mahon P, et al. The effect of maternal vitamin D concentration on fetal bone. J Clin Endocrinol Metab. 2012;97(11):E2070-E2077.
19. Mokry LE, Ross S, Ahmad OS, et al. Vitamin D and risk of multiple sclerosis: a mendelian randomization study. PLoS Med. 2015;12(8): e1001866.