Spleen tyrosine kinase (SYK) is a potential target for the treatment of cutaneous lupus erythematosus patients

Experimental Dermatology

Volumn 25, Issue 5, 2016, Pages 375-379

  Braegelmann, Christine ^a   Hölzel, Michael ^a   Ludbrook, Valerie ^b   Dickson, Marion ^b   Turan, Nil ^b   Ferring Schmitt, Sandra ^a   Sternberg, Sonja ^a   Bieber, Thomas ^a   Kuhn, Annegret ^c   Wenzel, Joerg ^a  

^a UNIVERSITY OF BONN   (Germany)

^b GLAXOSMITHKLINE   (United Kingdom)

^c UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

Author keywords

Cutaneous lupus erythematosus; Innate immunity; Kinase inhibition; Targeted therapy

Indexed keywords

NUCLEIC ACID; PROTEIN KINASE SYK; CYTOKINE; SYK PROTEIN, HUMAN;

ADULT; ARTICLE; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; GENE EXPRESSION; HUMAN; IMMUNOCOMPETENT CELL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; KERATINOCYTE; NORMAL HUMAN; PROTEIN EXPRESSION; REGULATORY MECHANISM; SKIN BIOPSY; SKIN LUPUS ERYTHEMATOSUS; TREATMENT OUTCOME; UPREGULATION; CASE CONTROL STUDY; CELL CULTURE; ENZYMOLOGY; METABOLISM; PHOSPHORYLATION;

CASE-CONTROL STUDIES; CELLS, CULTURED; CYTOKINES; HUMANS; LUPUS ERYTHEMATOSUS, CUTANEOUS; PHOSPHORYLATION; SYK KINASE;

EID: 84966600302     PISSN: 09066705     EISSN: 16000625     Source Type: Journal    
DOI: 10.1111/exd.12986     Document Type: Article

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