Gene Xpert for direct detection of Mycobacterium Tuberculosis in stool specimens from children with presumptive pulmonary tuberculosis

Annals of Clinical and Laboratory Science

Volumn 46, Issue 2, 2016, Pages 198-203

  Moussa, Husseiny Sh ^a   Bayoumi, Faten Sayed ^b,c   Mohamed, Ahmed Mohamed Ali ^d  

^a Ain Shams University   (Egypt)

^b October University for Modern Sciences and Arts   (Egypt)

^c NATIONAL RESEARCH CENTRE   (Egypt)

^d Egyptian Company of Serum and Vaccines   (Egypt)

Author keywords

Children; Gene Xpert; Mycobacterium tuberculosis; Pulmonary tuberculosis

Indexed keywords

ADOLESCENT; ARTICLE; BACTERIUM DETECTION; CHILD; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FECES ANALYSIS; FECES CULTURE; FEMALE; GOLD STANDARD; HUMAN; INFANT; LUNG TUBERCULOSIS; MAJOR CLINICAL STUDY; MALE; MYCOBACTERIUM TUBERCULOSIS; POLYMERASE CHAIN REACTION SYSTEM; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; SENSITIVITY AND SPECIFICITY; DEMOGRAPHY; FECES; GENETICS; ISOLATION AND PURIFICATION; MICROBIOLOGY; PRESCHOOL CHILD; PROCEDURES; REPRODUCIBILITY;

ADOLESCENT; CHILD; CHILD, PRESCHOOL; DEMOGRAPHY; FECES; FEMALE; HUMANS; INFANT; MALE; MYCOBACTERIUM TUBERCULOSIS; REAL-TIME POLYMERASE CHAIN REACTION; REPRODUCIBILITY OF RESULTS; TUBERCULOSIS, PULMONARY;

EID: 84966593827     PISSN: 00917370     EISSN: 15508080     Source Type: Journal    
DOI: None     Document Type: Article

References (26)

1. Dye C, Scheele S, Dolin P, Pathania V, Raviglione MC. Global burden of tuberculosis: estimated incidence, prevalence, and mortality by country. Jama. 1999;282(7):677-86
2. WHO. Global Tuberculosis Control. World Health Organization, Geneva, (2014)
3. El Din MAT, El Maraghy AA, Hay AHRA. Adverse reactions among patients being treated for multi-drug resistant tuberculosis at Abbassia Chest Hospital. Egyptian Journal of Chest Diseases and Tuberculosis. 2015
4. Marais BJ, Graham SM, Maeurer M, Zumla A. Progress and challenges in childhood tuberculosis. The Lancet infectious diseases. 2013;13(4):287-9
5. Khan EA, Starke JR. Diagnosis of tuberculosis in children: increased need for better methods. Emerging infectious diseases. 1995;1(4):115
6. Welday SH, Kimang'a AN, Kabera BM, Mburu JW, Mwachari C, Mungai E, et al. Stool as Appropriate Sample for the Diagnosis of Mycobacterium tuberculosis by Gene Xpert Test. Open Journal of Respiratory Diseases. 2014;2014
7. Cordova J, Shiloh R, Gilman RH, Sheen P, Martin L, Arenas F, et al. Evaluation of molecular tools for detection and drug susceptibility testing of Mycobacterium tuberculosis in stool specimens from patients with pulmonary tuberculosis. Journal of clinical microbiology. 2010;48(5):1820-6
8. Lawn SD, Brooks SV, Kranzer K, Nicol MP, Whitelaw A, Vogt M, et al. Screening for HIV-associated tuberculosis and rifampicin resistance before antiretroviral therapy using the Xpert MTB/RIF assay: a prospective study. PLoS medicine. 2011;8(7):e1001067
9. O'Grady J, Maeurer M, Mwaba P, Kapata N, Bates M, Hoelscher M, et al. New and improved diagnostics for detection of drug-resistant pulmonary tuberculosis. Current opinion in pulmonary medicine. 2011;17(3):134-41
10. Boehme CC, Nabeta P, Hillemann D, Nicol MP, Shenai S, Krapp F, et al. Rapid molecular detection of tuberculosis and rifampin resistance. New England Journal of Medicine. 2010;363(11):1005-15
11. Helb D, Jones M, Story E, Boehme C, Wallace E, Ho K, et al. Rapid detection of Mycobacterium tuberculosis and rifampin resistance by use of on-demand, near-patient technology. Journal of clinical microbiology. 2010;48(1):229-37
12. Boehme CC, Nicol MP, Nabeta P, Michael JS, Gotuzzo E, Tahirli R, et al. Feasibility, diagnostic accuracy, and effectiveness of decentralised use of the Xpert MTB/RIF test for diagnosis of tuberculosis and multidrug resistance: a multicentre implementation study. The lancet. 2011;377(9776):1495-505
13. Graham SM, Ahmed T, Amanullah F, Browning R, Cardenas V, Casenghi M, et al. Evaluation of tuberculosis diagnostics in children: 1. Proposed clinical case definitions for classification of intrathoracic tuberculosis disease. Consensus from an expert panel. Journal of Infectious Diseases. 2012;205(suppl 2):S199-S208
14. Zar HJ, Hanslo D, Apolles P, Swingler G, Hussey G. Induced sputum versus gastric lavage for microbiological confirmation of pulmonary tuberculosis in infants and young children: a prospective study. The Lancet. 2005;365(9454):130-4
15. Kawai V, Soto G, Gilman RH, Bautista CT, Caviedes L, Huaroto L, et al. Tuberculosis mortality, drug resistance, and infectiousness in patients with and without HIV infection in Peru. The American journal of tropical medicine and hygiene. 2006;75(6):1027-33
16. Woods GL, Brown-Elliott B, Desmond EP, Hall GS, Heifets L, Pfyffer GE, et al. Susceptibility testing of mycobacteria, nocardiae, and other aerobic actinomycetes: approved standard: NCCLS; 2003
17. Kokuto H, Sasaki Y, Yoshimatsu S, Mizuno K, Yi L, Mitarai S, editors. Detection of Mycobacterium tuberculosis in fecal specimens from adults diagnosed with pulmonary tuberculosis using the XpertMTB/RIF test. Open Forum Infectious Diseases; 2015: Oxford University Press
18. Nicol MP, Spiers K, Workman L, Isaacs W, Munro J, Black F, et al. Xpert MTB/RIF testing of stool samples for the diagnosis of pulmonary tuberculosis in children. Clinical Infectious Diseases. 2013;57(3):e18-e21
19. Zweig MH, Campbell G. Receiver-operating characteristic (ROC) plots: a fundamental evaluation tool in clinical medicine. Clinical chemistry. 1993;39(4):561-77
20. Brodie D, Schluger NW. The diagnosis of tuberculosis. Clinics in chest medicine. 2005;26(2):247-71
21. Triasih R, Graham SM. Limitations of the Indonesian Pediatric Tuberculosis Scoring System in the context of child contact investigation. Paediatr Indones. 2011;51:332-7
22. Lawn SD, Nicol MP. Xpert® MTB/RIF assay: development, evaluation and implementation of a new rapid molecular diagnostic for tuberculosis and rifampicin resistance. Future microbiology. 2011;6(9):1067-82
23. Steingart KR, Schiller I, Horne DJ, Pai M, Boehme CC, Dendukuri N. Xpert® MTB/RIF assay for pulmonary tuberculosis and rifampicin resistance in adults. Cochrane Database Syst Rev. 2014;1
24. Chang K, Lu W, Wang J, Zhang K, Jia S, Li F, et al. Rapid and effective diagnosis of tuberculosis and rifampicin resistance with Xpert MTB/RIF assay: a meta-analysis. Journal of Infection. 2012;64(6):580-8
25. Welday SH. Gene Xpert Testing Of Stool Samples for the Diagnosis of Pulmonary Tuberculosis in Children Less Than 15 Years in Hospitals In and Around Nairobi 2015
26. Nicol MP, Workman L, Isaacs W, Munro J, Black F, Eley B, et al. Accuracy of the Xpert MTB/RIF test for the diagnosis of pulmonary tuberculosis in children admitted to hospital in Cape Town, South Africa: a descriptive study. The Lancet infectious diseases. 2011;11(11):819-24