Voltage-gated potassium channel antibodies

Neurology

Volumn 86, Issue 18, 2016, Pages 1657-1658

  Graus, Francesc ^a   Gorman, Mark P ^b  

^a UNIVERSITY OF BARCELONA   (Spain)

^b BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; UNCLASSIFIED DRUG; VOLTAGE GATED POTASSIUM CHANNEL; VOLTAGE GATED POTASSIUM CHANNEL ANTIBODY; AUTOANTIBODY;

ACUTE DISSEMINATED ENCEPHALOMYELITIS; CANCER SCREENING; CEREBROSPINAL FLUID; EATON LAMBERT SYNDROME; EDITORIAL; HUMAN; IMMUNOASSAY; IMMUNOPRECIPITATION; IMMUNOTHERAPY; MYASTHENIA GRAVIS; PRIORITY JOURNAL; RADIOIMMUNOASSAY; CHANNEL GATING;

ANTIBODIES; AUTOANTIBODIES; HUMANS; ION CHANNEL GATING; POTASSIUM CHANNELS, VOLTAGE-GATED;

EID: 84966487114     PISSN: 00283878     EISSN: 1526632X     Source Type: Journal    
DOI: 10.1212/WNL.0000000000002644     Document Type: Editorial

References (10)

1. Vincent A, Roberts M, Willison H, Lang B, Newsom-Davis J. Autoantibodies, neurotoxins and the nervous system. J Physiol Paris 1995; 89: 129-136
2. Vincent A, Buckley C, Schott JM, et al. Potassium channel antibody-associated encephalopathy: a potentially immunotherapy-responsive form of limbic encephalitis. Brain 2004; 127: 701-712
3. Paterson RW, Zandi MS, Armstrong R, Vincent A, Schott JM. Clinical relevance of positive Voltage-gated potassium channel (VGKC)-complex antibodies: experience from a tertiary referral centre. J Neurol Neurosurg Psychiatry 2014; 85: 625-630
4. Klein CJ, Lennon VA, Aston PA, et al. Insights from LGI1 and CASPR2 potassium channel complex autoantibody subtyping. JAMA Neurol 2013; 70: 229-234
5. Tan KM, Lennon VA, Klein CJ, Boeve BF, Pittock SJ. Clinical spectrum of Voltage-gated potassium channel autoimmunity. Neurology 2008; 70: 1883-1890
6. Lai M, Huijbers MG, Lancaster E, et al. Investigation of LGI1 as the antigen in limbic encephalitis previously attributed to potassium channels: a case series. Lancet Neurol 2010; 9: 776-785
7. Irani SR, Alexander S, Waters P, et al. Antibodies to KV1 potassium channel-complex proteins leucine-rich, glioma inactivated 1 protein and contactin-associated protein-2 in limbic encephalitis, Morvans syndrome and acquired neuromyotonia. Brain 2010; 133: 2734-2748
8. Hacohen Y, Singh R, Rossi M, et al. Clinical relevance of Voltage-gated potassium channel-complex antibodies in children. Neurology 2015; 85: 967-975
9. Van Sonderen A, Schreurs MWJ, De Bruijn MAAM, et al. The relevance of VGKC positivity in the absence of LGI1 and Caspr2 antibodies. Neurology 2016; 86: 1692-1699
10. Irani SR, Pettingill P, Kleopa KA, et al. Morvan syndrome: clinical and serological observations in 29 cases. Ann Neurol 2012; 72: 241-255