Inhibition of DNA topoisomerase I and growth inhibition of human cancer cell lines by an oleanane from Junellia aspera (Verbenaceae)

Cellular and Molecular Biology

Volumn 53, Issue 3, 2007, Pages 13-17

  Pungitore, C R ^a   Padron J M ^b,c   Leon, L G ^b,c   Garcia C ^c   Ciuffo, G M ^a   Martin, V S ^c   Tonn, C E ^a  

^a UNIVERSIDAD NACIONAL DE SAN LUIS   (Argentina)

^b Madrid Spain   (Spain)

^c UNIVERSIDAD DE LA LAGUNA   (Spain)

Author keywords

Anticancer drugs; DNA topoisomerase inhibitors; Junellia aspera; Solid tumours; Triterpenes

Indexed keywords

3BETA ACETOXYOLEAN 12ALPHA BROMINE(28-13)OLIDE; DAUCOSTEROL; DNA POLYMERASE; DNA TOPOISOMERASE; DNA TOPOISOMERASE INHIBITOR; JUNELLIA ASPERA EXTRACT; MASLINIC ACID; MASLINIC ACID DIACETATE; METHYL OLEANATE; OLEANOLIC ACID; OLEANOLIC ACID ACETATE; PLANT EXTRACT; TRITERPENOID; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; CANCER CELL CULTURE; CANCER GROWTH; CANCER INHIBITION; CHEMOSENSITIVITY; COMPUTER SIMULATION; CONFERENCE PAPER; CONTROLLED STUDY; DNA METABOLISM; DRUG MECHANISM; ENZYME INHIBITION; ENZYME STRUCTURE; HUMAN; HUMAN CELL; IC 50; JUNELLIA ASPERA; POLYMERASE CHAIN REACTION; VERBENACEAE;

JUNELLIA; VERBENACEAE;

EID: 84965098356     PISSN: 01455680     EISSN: 1165158X     Source Type: Journal    
DOI: 10.1170/T791     Document Type: Article

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