β-amyloid induces a dying-back process and remote trans-synaptic alterations in a microfluidic-based reconstructed neuronal network

Acta Neuropathologica Communications

Volumn 2, Issue 1, 2014, Pages

  Deleglise, Bérangére ^a,b,c   Magnifico, Sebastien ^b,c   Duplus, Eric ^a,b,c   Vaur, Pauline ^a,b,c   Soubeyre, Vanessa ^b,c   Belle, Morgane ^b,c   Vignes, Maeva ^b,c,d,e   Viovy, Jean Louis ^d,e   Jacotot, Etienne ^a,b,c,f   Peyrin, Jean Michel ^a,b,c   Brugg, Bernard ^a,b,c  

^a Département de Biologie   (France)

^b Université Pierre et Marie Curie   (France)

^c SORBONNE UNIVERSITÉ   (France)

^d INSTITUT CURIE   (France)

^e INSTITUT CURIE   (France)

^f HAMMERSMITH HOSPITAL   (United Kingdom)

Author keywords

Axonal degeneration; Microfluidics; Neuronal network; Synapse loss; Tau

Indexed keywords

AMYLOID BETA PROTEIN; MAPT PROTEIN, MOUSE; TAU PROTEIN;

ANIMAL; BRAIN CORTEX; DRUG EFFECTS; METABOLISM; MICROFLUIDIC ANALYSIS; MOUSE; NERVE CELL; NERVE CELL NETWORK; NERVE FIBER; PATHOLOGY; PHOSPHORYLATION; PRIMARY CELL CULTURE; PROCEDURES; SYNAPSE;

AMYLOID BETA-PEPTIDES; ANIMALS; AXONS; CEREBRAL CORTEX; MICE; MICROFLUIDIC ANALYTICAL TECHNIQUES; NERVE NET; NEURONS; PHOSPHORYLATION; PRIMARY CELL CULTURE; SYNAPSES; TAU PROTEINS;

EID: 84965087631     PISSN: None     EISSN: 20515960     Source Type: Journal    
DOI: 10.1186/s40478-014-0145-3     Document Type: Article

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