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Volumn 23, Issue 6, 2016, Pages 608-618

Multilayered proteomics reveals molecular switches dictating ligand-dependent EGFR trafficking

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; LIGAND; PROTEOME; RAB7 PROTEIN; TRANSFORMING GROWTH FACTOR ALPHA; EGFR PROTEIN, HUMAN; EPIDERMAL GROWTH FACTOR; MEMBRANE PROTEIN; RAB PROTEIN; RAB11FIP1 PROTEIN, HUMAN; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

EID: 84965006770     PISSN: 15459993     EISSN: 15459985     Source Type: Journal    
DOI: 10.1038/nsmb.3218     Document Type: Article
Times cited : (82)

References (68)
  • 1
    • 33847392514 scopus 로고    scopus 로고
    • Untangling the signalling wires
    • Kholodenko, B. N. Untangling the signalling wires. Nat. Cell Biol. 9, 247-249 (2007).
    • (2007) Nat. Cell Biol. , vol.9 , pp. 247-249
    • Kholodenko, B.N.1
  • 2
    • 84880441014 scopus 로고    scopus 로고
    • Temporal regulation of EGF signalling networks by the scaffold protein Shc1
    • Zheng, Y. et al. Temporal regulation of EGF signalling networks by the scaffold protein Shc1. Nature 499, 166-171 (2013).
    • (2013) Nature , vol.499 , pp. 166-171
    • Zheng, Y.1
  • 3
    • 84874765320 scopus 로고    scopus 로고
    • Encoding and decoding cellular information through signaling dynamics
    • Purvis, J. E.&Lahav, G. Encoding and decoding cellular information through signaling dynamics. Cell 152, 945-956 (2013).
    • (2013) Cell , vol.152 , pp. 945-956
    • Purvis, J.E.1    Lahav, G.2
  • 4
    • 84858665104 scopus 로고    scopus 로고
    • Suppression of EGFR endocytosis by dynamin depletion reveals that EGFR signaling occurs primarily at the plasma membrane
    • Sousa, L. P. et al. Suppression of EGFR endocytosis by dynamin depletion reveals that EGFR signaling occurs primarily at the plasma membrane. Proc. Natl. Acad. Sci. USA 109, 4419-4424 (2012).
    • (2012) Proc. Natl. Acad. Sci. USA , vol.109 , pp. 4419-4424
    • Sousa, L.P.1
  • 5
    • 0030461226 scopus 로고    scopus 로고
    • Control of EGF receptor signaling by clathrin-mediated endocytosis
    • Vieira, A. V., Lamaze, C.&Schmid, S. L. Control of EGF receptor signaling by clathrin-mediated endocytosis. Science 274, 2086-2089 (1996).
    • (1996) Science , vol.274 , pp. 2086-2089
    • Vieira, A.V.1    Lamaze, C.2    Schmid, S.L.3
  • 6
    • 84964694996 scopus 로고    scopus 로고
    • Regulation of EGFR signal transduction by analogue-to-digital conversion in endosomes
    • Villaseñor, R., Nonaka, H., Del Conte-Zerial, P., Kalaidzidis, Y.&Zerial, M. Regulation of EGFR signal transduction by analogue-to-digital conversion in endosomes. eLife 4, e06156 (2015).
    • (2015) ELife , vol.4 , pp. e06156
    • Villaseñor, R.1    Nonaka, H.2    Del Conte-Zerial, P.3    Kalaidzidis, Y.4    Zerial, M.5
  • 7
    • 50649123584 scopus 로고    scopus 로고
    • Proliferation versus migration in platelet-derived growth factor signaling: The key role of endocytosis
    • De Donatis, A. et al. Proliferation versus migration in platelet-derived growth factor signaling: The key role of endocytosis. J. Biol. Chem. 283, 19948-19956 (2008).
    • (2008) J. Biol. Chem. , vol.283 , pp. 19948-19956
    • De Donatis, A.1
  • 8
    • 76149123944 scopus 로고    scopus 로고
    • The binding of NCAM to FGFR1 induces a specific cellular response mediated by receptor trafficking
    • Francavilla, C. et al. The binding of NCAM to FGFR1 induces a specific cellular response mediated by receptor trafficking. J. Cell Biol. 187, 1101-1116 (2009).
    • (2009) J. Cell Biol. , vol.187 , pp. 1101-1116
    • Francavilla, C.1
  • 9
    • 84884586861 scopus 로고    scopus 로고
    • Functional proteomics defines the molecular switch underlying FGF receptor trafficking and cellular outputs
    • Francavilla, C. et al. Functional proteomics defines the molecular switch underlying FGF receptor trafficking and cellular outputs. Mol. Cell 51, 707-722 (2013).
    • (2013) Mol. Cell , vol.51 , pp. 707-722
    • Francavilla, C.1
  • 10
    • 79958214335 scopus 로고    scopus 로고
    • GGA3 functions as a switch to promote Met receptor recycling, essential for sustained ERK and cell migration
    • Parachoniak, C. A., Luo, Y., Abella, J. V., Keen, J. H.&Park, M. GGA3 functions as a switch to promote Met receptor recycling, essential for sustained ERK and cell migration. Dev. Cell 20, 751-763 (2011).
    • (2011) Dev. Cell , vol.20 , pp. 751-763
    • Parachoniak, C.A.1    Luo, Y.2    Abella, J.V.3    Keen, J.H.4    Park, M.5
  • 11
    • 84856698420 scopus 로고    scopus 로고
    • Endocytosis and signaling: Cell logistics shape the eukaryotic cell plan
    • Sigismund, S. et al. Endocytosis and signaling: cell logistics shape the eukaryotic cell plan. Physiol. Rev. 92, 273-366 (2012).
    • (2012) Physiol. Rev. , vol.92 , pp. 273-366
    • Sigismund, S.1
  • 13
    • 78751498756 scopus 로고    scopus 로고
    • Functional selectivity and biased receptor signaling
    • Kenakin, T. Functional selectivity and biased receptor signaling. J. Pharmacol. Exp. Ther. 336, 296-302 (2011).
    • (2011) J. Pharmacol. Exp. Ther. , vol.336 , pp. 296-302
    • Kenakin, T.1
  • 14
    • 79251502034 scopus 로고    scopus 로고
    • Ligand-based receptor tyrosine kinase partial agonists: New paradigm for cancer drug discovery?
    • Riese, D. J., II. Ligand-based receptor tyrosine kinase partial agonists: new paradigm for cancer drug discovery? Expert Opin. Drug Discov. 6, 185-193 (2011).
    • (2011) Expert Opin. Drug Discov. , vol.6 , pp. 185-193
    • Riese, D.J.1    Ii2
  • 15
    • 84908880944 scopus 로고    scopus 로고
    • Cell and molecular biology of epidermal growth factor receptor
    • Ceresa, B. P.&Peterson, J. L. Cell and molecular biology of epidermal growth factor receptor. Int. Rev. Cell Mol. Biol. 313, 145-178 (2014).
    • (2014) Int. Rev. Cell Mol. Biol. , vol.313 , pp. 145-178
    • Ceresa, B.P.1    Peterson, J.L.2
  • 16
    • 67649889124 scopus 로고    scopus 로고
    • Differential effects of EGFR ligands on endocytic sorting of the receptor
    • Roepstorff, K. et al. Differential effects of EGFR ligands on endocytic sorting of the receptor. Traffic 10, 1115-1127 (2009).
    • (2009) Traffic , vol.10 , pp. 1115-1127
    • Roepstorff, K.1
  • 17
    • 77949424084 scopus 로고    scopus 로고
    • Systems survey of endocytosis by multiparametric image analysis
    • Collinet, C. et al. Systems survey of endocytosis by multiparametric image analysis. Nature 464, 243-249 (2010).
    • (2010) Nature , vol.464 , pp. 243-249
    • Collinet, C.1
  • 18
    • 84902089978 scopus 로고    scopus 로고
    • A hierarchical map of regulatory genetic interactions in membrane trafficking
    • Liberali, P., Snijder, B.&Pelkmans, L. A hierarchical map of regulatory genetic interactions in membrane trafficking. Cell 157, 1473-1487 (2014).
    • (2014) Cell , vol.157 , pp. 1473-1487
    • Liberali, P.1    Snijder, B.2    Pelkmans, L.3
  • 19
    • 84871297843 scopus 로고    scopus 로고
    • Next-generation proteomics: Towards an integrative view of proteome dynamics
    • Altelaar, A. F., Munoz, J.&Heck, A. J. Next-generation proteomics: Towards an integrative view of proteome dynamics. Nat. Rev. Genet. 14, 35-48 (2013).
    • (2013) Nat. Rev. Genet. , vol.14 , pp. 35-48
    • Altelaar, A.F.1    Munoz, J.2    Heck, A.J.3
  • 20
    • 84929709547 scopus 로고    scopus 로고
    • Quantitative interaction proteomics of neurodegenerative disease proteins
    • Hosp, F. et al. Quantitative interaction proteomics of neurodegenerative disease proteins. Cell Rep. 11, 1134-1146 (2015).
    • (2015) Cell Rep. , vol.11 , pp. 1134-1146
    • Hosp, F.1
  • 21
    • 84929129370 scopus 로고    scopus 로고
    • Multidimensional proteomics for cell biology
    • Larance, M.&Lamond, A. I. Multidimensional proteomics for cell biology. Nat. Rev. Mol. Cell Biol. 16, 269-280 (2015).
    • (2015) Nat. Rev. Mol. Cell Biol. , vol.16 , pp. 269-280
    • Larance, M.1    Lamond, A.I.2
  • 22
    • 84890644637 scopus 로고    scopus 로고
    • Status of large-scale analysis of post-translational modifications by mass spectrometry
    • Olsen, J. V.&Mann, M. Status of large-scale analysis of post-translational modifications by mass spectrometry. Mol. Cell. Proteomics 12, 3444-3452 (2013).
    • (2013) Mol. Cell. Proteomics , vol.12 , pp. 3444-3452
    • Olsen, J.V.1    Mann, M.2
  • 23
    • 84894460034 scopus 로고    scopus 로고
    • When ubiquitination meets phosphorylation: A systems biology perspective of EGFR/MAPK signalling
    • Nguyen, L. K., Kolch, W.&Kholodenko, B. N. When ubiquitination meets phosphorylation: A systems biology perspective of EGFR/MAPK signalling. Cell Commun. Signal. 11, 52 (2013).
    • (2013) Cell Commun. Signal. , vol.11 , pp. 52
    • Nguyen, L.K.1    Kolch, W.2    Kholodenko, B.N.3
  • 24
    • 78751496279 scopus 로고    scopus 로고
    • Proteomic snapshot of the EGF-induced ubiquitin network
    • Argenzio, E. et al. Proteomic snapshot of the EGF-induced ubiquitin network. Mol. Syst. Biol. 7, 462 (2011).
    • (2011) Mol. Syst. Biol. , vol.7 , pp. 462
    • Argenzio, E.1
  • 25
    • 84889244041 scopus 로고    scopus 로고
    • Perturbation of the mutated EGFR interactome identifies vulnerabilities and resistance mechanisms
    • Li, J. et al. Perturbation of the mutated EGFR interactome identifies vulnerabilities and resistance mechanisms. Mol. Syst. Biol. 9, 705 (2013).
    • (2013) Mol. Syst. Biol. , vol.9 , pp. 705
    • Li, J.1
  • 26
    • 33750456519 scopus 로고    scopus 로고
    • Global, in vivo, and site-specific phosphorylation dynamics in signaling networks
    • Olsen, J. V. et al. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. Cell 127, 635-648 (2006).
    • (2006) Cell , vol.127 , pp. 635-648
    • Olsen, J.V.1
  • 27
    • 84868320002 scopus 로고    scopus 로고
    • Global snapshot of the influence of endocytosis upon EGF receptor signaling output
    • Omerovic, J., Hammond, D. E., Prior, I. A.&Clague, M. J. Global snapshot of the influence of endocytosis upon EGF receptor signaling output. J. Proteome Res. 11, 5157-5166 (2012).
    • (2012) J. Proteome Res. , vol.11 , pp. 5157-5166
    • Omerovic, J.1    Hammond, D.E.2    Prior, I.A.3    Clague, M.J.4
  • 28
    • 14544306526 scopus 로고    scopus 로고
    • Clathrin-independent endocytosis of ubiquitinated cargos
    • Sigismund, S. et al. Clathrin-independent endocytosis of ubiquitinated cargos. Proc. Natl. Acad. Sci. USA 102, 2760-2765 (2005).
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 2760-2765
    • Sigismund, S.1
  • 29
    • 48549088895 scopus 로고    scopus 로고
    • Clathrin-mediated internalization is essential for sustained EGFR signaling but dispensable for degradation
    • Sigismund, S. et al. Clathrin-mediated internalization is essential for sustained EGFR signaling but dispensable for degradation. Dev. Cell 15, 209-219 (2008).
    • (2008) Dev. Cell , vol.15 , pp. 209-219
    • Sigismund, S.1
  • 30
    • 84901247682 scopus 로고    scopus 로고
    • From wavy hair to naked proteins: The role of transforming growth factor alpha in health and disease
    • Singh, B.&Coffey, R. J. From wavy hair to naked proteins: The role of transforming growth factor alpha in health and disease. Semin. Cell Dev. Biol. 28, 12-21 (2014).
    • (2014) Semin. Cell Dev. Biol. , vol.28 , pp. 12-21
    • Singh, B.1    Coffey, R.J.2
  • 31
    • 84934295586 scopus 로고    scopus 로고
    • Systems-wide analysis of BCR signalosomes and downstream phosphorylation and ubiquitylation
    • Satpathy, S. et al. Systems-wide analysis of BCR signalosomes and downstream phosphorylation and ubiquitylation. Mol. Syst. Biol. 11, 810 (2015).
    • (2015) Mol. Syst. Biol. , vol.11 , pp. 810
    • Satpathy, S.1
  • 32
    • 80855128254 scopus 로고    scopus 로고
    • Deep proteome and transcriptome mapping of a human cancer cell line
    • Nagaraj, N. et al. Deep proteome and transcriptome mapping of a human cancer cell line. Mol. Syst. Biol. 7, 548 (2011).
    • (2011) Mol. Syst. Biol. , vol.7 , pp. 548
    • Nagaraj, N.1
  • 33
    • 62649159446 scopus 로고    scopus 로고
    • Endocytosis and intracellular trafficking of ErbBs
    • Sorkin, A.&Goh, L. K. Endocytosis and intracellular trafficking of ErbBs. Exp. Cell Res. 315, 683-696 (2009).
    • (2009) Exp. Cell Res. , vol.315 , pp. 683-696
    • Sorkin, A.1    Goh, L.K.2
  • 34
    • 53749092962 scopus 로고    scopus 로고
    • Rab-coupling protein coordinates recycling of alpha5beta1 integrin and EGFR1 to promote cell migration in 3D microenvironments
    • Caswell, P. T. et al. Rab-coupling protein coordinates recycling of alpha5beta1 integrin and EGFR1 to promote cell migration in 3D microenvironments. J. Cell Biol. 183, 143-155 (2008).
    • (2008) J. Cell Biol. , vol.183 , pp. 143-155
    • Caswell, P.T.1
  • 35
    • 79952752375 scopus 로고    scopus 로고
    • System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation
    • Rigbolt, K. T. et al. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. Sci. Signal. 4, rs3 (2011).
    • (2011) Sci. Signal. , vol.4 , pp. rs3
    • Rigbolt, K.T.1
  • 36
    • 57749112131 scopus 로고    scopus 로고
    • Mechanistic insight into site-restricted monoubiquitination of FANCD2 by Ube2t, FANCL, and FANCI
    • Alpi, A. F., Pace, P. E., Babu, M. M.&Patel, K. J. Mechanistic insight into site-restricted monoubiquitination of FANCD2 by Ube2t, FANCL, and FANCI. Mol. Cell 32, 767-777 (2008).
    • (2008) Mol. Cell , vol.32 , pp. 767-777
    • Alpi, A.F.1    Pace, P.E.2    Babu, M.M.3    Patel, K.J.4
  • 37
    • 0030871891 scopus 로고    scopus 로고
    • BAG-1 modulates the chaperone activity of Hsp70/Hsc70
    • Takayama, S. et al. BAG-1 modulates the chaperone activity of Hsp70/Hsc70. EMBO J. 16, 4887-4896 (1997).
    • (1997) EMBO J. , vol.16 , pp. 4887-4896
    • Takayama, S.1
  • 38
    • 36749010218 scopus 로고    scopus 로고
    • The age of crosstalk: Phosphorylation, ubiquitination, and beyond
    • Hunter, T. The age of crosstalk: phosphorylation, ubiquitination, and beyond. Mol. Cell 28, 730-738 (2007).
    • (2007) Mol. Cell , vol.28 , pp. 730-738
    • Hunter, T.1
  • 39
    • 33644869303 scopus 로고    scopus 로고
    • Rab7 activity affects epidermal growth factor:epidermal growth factor receptor degradation by regulating endocytic trafficking from the late endosome
    • Ceresa, B. P.&Bahr, S. J. Rab7 activity affects epidermal growth factor:epidermal growth factor receptor degradation by regulating endocytic trafficking from the late endosome. J. Biol. Chem. 281, 1099-1106 (2006).
    • (2006) J. Biol. Chem. , vol.281 , pp. 1099-1106
    • Ceresa, B.P.1    Bahr, S.J.2
  • 40
    • 67249150119 scopus 로고    scopus 로고
    • Rab7: Roles in membrane trafficking and disease
    • Zhang, M., Chen, L., Wang, S.&Wang, T. Rab7: roles in membrane trafficking and disease. Biosci. Rep. 29, 193-209 (2009).
    • (2009) Biosci. Rep. , vol.29 , pp. 193-209
    • Zhang, M.1    Chen, L.2    Wang, S.3    Wang, T.4
  • 41
    • 33644852909 scopus 로고    scopus 로고
    • Differential regulation of EGF receptor internalization and degradation by multiubiquitination within the kinase domain
    • Huang, F., Kirkpatrick, D., Jiang, X., Gygi, S.&Sorkin, A. Differential regulation of EGF receptor internalization and degradation by multiubiquitination within the kinase domain. Mol. Cell 21, 737-748 (2006).
    • (2006) Mol. Cell , vol.21 , pp. 737-748
    • Huang, F.1    Kirkpatrick, D.2    Jiang, X.3    Gygi, S.4    Sorkin, A.5
  • 42
    • 84881446387 scopus 로고    scopus 로고
    • Threshold-controlled ubiquitination of the EGFR directs receptor fate
    • Sigismund, S. et al. Threshold-controlled ubiquitination of the EGFR directs receptor fate. EMBO J. 32, 2140-2157 (2013).
    • (2013) EMBO J. , vol.32 , pp. 2140-2157
    • Sigismund, S.1
  • 43
    • 77951644400 scopus 로고    scopus 로고
    • Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis
    • Olsen, J. V. et al. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. Sci. Signal. 3, ra3 (2010).
    • (2010) Sci. Signal. , vol.3 , pp. ra3
    • Olsen, J.V.1
  • 44
    • 84865339184 scopus 로고    scopus 로고
    • Recycling of EGFR and ErbB2 is associated with impaired Hrs tyrosine phosphorylation and decreased deubiquitination by AMSH
    • Meijer, I. M., van Rotterdam, W., van Zoelen, E. J.&van Leeuwen, J. E. Recycling of EGFR and ErbB2 is associated with impaired Hrs tyrosine phosphorylation and decreased deubiquitination by AMSH. Cell. Signal. 24, 1981-1988 (2012).
    • (2012) Cell. Signal. , vol.24 , pp. 1981-1988
    • Meijer, I.M.1    Van Rotterdam, W.2    Van Zoelen, E.J.3    Van Leeuwen, J.E.4
  • 45
    • 84879637572 scopus 로고    scopus 로고
    • Integrated proteomic analysis of post-translational modifications by serial enrichment
    • Mertins, P. et al. Integrated proteomic analysis of post-translational modifications by serial enrichment. Nat. Methods 10, 634-637 (2013).
    • (2013) Nat. Methods , vol.10 , pp. 634-637
    • Mertins, P.1
  • 46
    • 84922537688 scopus 로고    scopus 로고
    • Ultradeep human phosphoproteome reveals a distinct regulatory nature of Tyr and Ser/Thr-based signaling
    • Sharma, K. et al. Ultradeep human phosphoproteome reveals a distinct regulatory nature of Tyr and Ser/Thr-based signaling. Cell Rep. 8, 1583-1594 (2014).
    • (2014) Cell Rep. , vol.8 , pp. 1583-1594
    • Sharma, K.1
  • 47
    • 59749089436 scopus 로고    scopus 로고
    • ESCRT proteins, endosome organization and mitogenic receptor down-regulation
    • Woodman, P. ESCRT proteins, endosome organization and mitogenic receptor down-regulation. Biochem. Soc. Trans. 37, 146-150 (2009).
    • (2009) Biochem. Soc. Trans. , vol.37 , pp. 146-150
    • Woodman, P.1
  • 49
    • 84872186679 scopus 로고    scopus 로고
    • Ubiquitylation of the chemokine receptor CCR7 enables efficient receptor recycling and cell migration
    • Schaeuble, K. et al. Ubiquitylation of the chemokine receptor CCR7 enables efficient receptor recycling and cell migration. J. Cell Sci. 125, 4463-4474 (2012).
    • (2012) J. Cell Sci. , vol.125 , pp. 4463-4474
    • Schaeuble, K.1
  • 50
    • 68849084073 scopus 로고    scopus 로고
    • RCP is a human breast cancer-promoting gene with Ras-activating function
    • Zhang, J. et al. RCP is a human breast cancer-promoting gene with Ras-activating function. J. Clin. Invest. 119, 2171-2183 (2009).
    • (2009) J. Clin. Invest. , vol.119 , pp. 2171-2183
    • Zhang, J.1
  • 51
    • 84885669414 scopus 로고    scopus 로고
    • The dynamics of signaling as a pharmacological target
    • Behar, M., Barken, D., Werner, S. L.&Hoffmann, A. The dynamics of signaling as a pharmacological target. Cell 155, 448-461 (2013).
    • (2013) Cell , vol.155 , pp. 448-461
    • Behar, M.1    Barken, D.2    Werner, S.L.3    Hoffmann, A.4
  • 52
    • 84925535544 scopus 로고    scopus 로고
    • Tuning cytokine receptor signaling by re-orienting dimer geometry with surrogate ligands
    • Moraga, I. et al. Tuning cytokine receptor signaling by re-orienting dimer geometry with surrogate ligands. Cell 160, 1196-1208 (2015).
    • (2015) Cell , vol.160 , pp. 1196-1208
    • Moraga, I.1
  • 53
    • 63049100044 scopus 로고    scopus 로고
    • Functional selectivity of EGF family peptide growth factors: Implications for cancer
    • Wilson, K. J., Gilmore, J. L., Foley, J., Lemmon, M. A.&Riese, D. J. II. Functional selectivity of EGF family peptide growth factors: implications for cancer. Pharmacol. Ther. 122, 1-8 (2009).
    • (2009) Pharmacol. Ther. , vol.122 , pp. 1-8
    • Wilson, K.J.1    Gilmore, J.L.2    Foley, J.3    Lemmon, M.A.4    Riese, D.J.I.I.5
  • 54
    • 84897136781 scopus 로고    scopus 로고
    • Individualized medicine from prewomb to tomb
    • Topol, E. J. Individualized medicine from prewomb to tomb. Cell 157, 241-253 (2014).
    • (2014) Cell , vol.157 , pp. 241-253
    • Topol, E.J.1
  • 55
    • 84874762979 scopus 로고    scopus 로고
    • The PRoteomics IDEntifications (PRIDE) database and associated tools: Status in 2013
    • Vizcaíno, J. A. et al. The PRoteomics IDEntifications (PRIDE) database and associated tools: status in 2013. Nucleic Acids Res. 41, D1063-D1069 (2013).
    • (2013) Nucleic Acids Res. , vol.41 , pp. D1063-D1069
    • Vizcaíno, J.A.1
  • 56
    • 84928383355 scopus 로고    scopus 로고
    • Dynamic caveolae exclude bulk membrane proteins and are required for sorting of excess glycosphingolipids
    • Shvets, E., Bitsikas, V., Howard, G., Hansen, C. G.&Nichols, B. J. Dynamic caveolae exclude bulk membrane proteins and are required for sorting of excess glycosphingolipids. Nat. Commun. 6, 6867 (2015).
    • (2015) Nat. Commun. , vol.6 , pp. 6867
    • Shvets, E.1    Bitsikas, V.2    Howard, G.3    Hansen, C.G.4    Nichols, B.J.5
  • 57
    • 80054033461 scopus 로고    scopus 로고
    • A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles
    • Wagner, S. A. et al. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. Mol. Cell. Proteomics 10, M111 013284 (2011).
    • (2011) Mol. Cell. Proteomics , vol.10 , pp. M111-13284
    • Wagner, S.A.1
  • 58
    • 67349266694 scopus 로고    scopus 로고
    • Universal sample preparation method for proteome analysis
    • Wisniewski, J. R., Zougman, A., Nagaraj, N.&Mann, M. Universal sample preparation method for proteome analysis. Nat. Methods 6, 359-362 (2009).
    • (2009) Nat. Methods , vol.6 , pp. 359-362
    • Wisniewski, J.R.1    Zougman, A.2    Nagaraj, N.3    Mann, M.4
  • 60
    • 80052384081 scopus 로고    scopus 로고
    • GeLCMS for in-depth protein characterization and advanced analysis of proteomes
    • Lundby, A.&Olsen, J. V. GeLCMS for in-depth protein characterization and advanced analysis of proteomes. Methods Mol. Biol. 753, 143-155 (2011).
    • (2011) Methods Mol. Biol. , vol.753 , pp. 143-155
    • Lundby, A.1    Olsen, J.V.2
  • 61
    • 34548183872 scopus 로고    scopus 로고
    • Protocol for micro-purification, enrichment, pre-fractionation and storage of peptides for proteomics using StageTips
    • Rappsilber, J., Mann, M.&Ishihama, Y. Protocol for micro-purification, enrichment, pre-fractionation and storage of peptides for proteomics using StageTips. Nat. Protoc. 2, 1896-1906 (2007).
    • (2007) Nat. Protoc. , vol.2 , pp. 1896-1906
    • Rappsilber, J.1    Mann, M.2    Ishihama, Y.3
  • 62
    • 84861800006 scopus 로고    scopus 로고
    • Optimized fast and sensitive acquisition methods for shotgun proteomics on a quadrupole orbitrap mass spectrometer
    • Kelstrup, C. D., Young, C., Lavallee, R., Nielsen, M. L.&Olsen, J. V. Optimized fast and sensitive acquisition methods for shotgun proteomics on a quadrupole orbitrap mass spectrometer. J. Proteome Res. 11, 3487-3497 (2012).
    • (2012) J. Proteome Res. , vol.11 , pp. 3487-3497
    • Kelstrup, C.D.1    Young, C.2    Lavallee, R.3    Nielsen, M.L.4    Olsen, J.V.5
  • 63
    • 57449099865 scopus 로고    scopus 로고
    • MaxQuant enables high peptide identification rates, individualized p. P. B.-range mass accuracies and proteome-wide protein quantification
    • Cox, J.&Mann, M. MaxQuant enables high peptide identification rates, individualized p. p. b.-range mass accuracies and proteome-wide protein quantification. Nat. Biotechnol. 26, 1367-1372 (2008).
    • (2008) Nat. Biotechnol. , vol.26 , pp. 1367-1372
    • Cox, J.1    Mann, M.2
  • 64
    • 79953701087 scopus 로고    scopus 로고
    • Andromeda: A peptide search engine integrated into the MaxQuant environment
    • Cox, J. et al. Andromeda: A peptide search engine integrated into the MaxQuant environment. J. Proteome Res. 10, 1794-1805 (2011).
    • (2011) J. Proteome Res. , vol.10 , pp. 1794-1805
    • Cox, J.1
  • 65
    • 80051631238 scopus 로고    scopus 로고
    • GProX, a user-friendly platform for bioinformatics analysis and visualization of quantitative proteomics data
    • Rigbolt, K. T., Vanselow, J. T.&Blagoev, B. GProX, a user-friendly platform for bioinformatics analysis and visualization of quantitative proteomics data. Mol. Cell. Proteomics 10, O110. 007450 (2011).
    • (2011) Mol. Cell. Proteomics , vol.10 , pp. 110-7450
    • Rigbolt, K.T.1    Vanselow, J.T.2    Blagoev, B.3
  • 66
    • 84876515907 scopus 로고    scopus 로고
    • STRING v9. 1: Protein-protein interaction networks, with increased coverage and integration
    • Franceschini, A. et al. STRING v9. 1: protein-protein interaction networks, with increased coverage and integration. Nucleic Acids Res. 41, D808-D815 (2013).
    • (2013) Nucleic Acids Res. , vol.41 , pp. D808-D815
    • Franceschini, A.1
  • 68
    • 61449172037 scopus 로고    scopus 로고
    • Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
    • Huang, W., Sherman, B. T.&Lempicki, R. A. Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat. Protoc. 4, 44-57 (2009).
    • (2009) Nat. Protoc. , vol.4 , pp. 44-57
    • Huang, W.1    Sherman, B.T.2    Lempicki, R.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.