Gabaa receptor and LGI1 antibody encephalitis in a patient with thymoma

Neurology: Neuroimmunology and NeuroInflammation

Volumn 2, Issue 2, 2015, Pages e73-

  Simabukuro, Mateus Mistieri ^a   Petit Pedrol, Mar ^b   Castro, Luiz H ^a   Nitrini, Ricardo ^a   Lucato, Leandro ^a   Zambon, Antônio Alberto ^a   Silva, Lis Gomes ^a   Fortes, Gabriela Carneiro Rosa ^a   Neto, Herval Ribeiro Soares ^a   Dalmau, Josep O ^b,c,d  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b INSTITUT D INVESTIGACIONS BIOMÈDIQUES AUGUST PI I SUNYER IDIBAPS   (Spain)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

^d INSTITUCIÓ CATALANA DE RECERCA I ESTUDIS AVANÇATS ICREA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; ANTINUCLEAR ANTIBODY; AZATHIOPRINE; C REACTIVE PROTEIN; CHOLINERGIC RECEPTOR; DOUBLE STRANDED DNA ANTIBODY; FLUORODEOXYGLUCOSE; METHYLPREDNISOLONE; PHENOBARBITAL; PREDNISONE; PYRIDOSTIGMINE;

ADULT; ALLERGIC ENCEPHALITIS; AMNESIA; BEHAVIOR CHANGE; BENIGN CHILDHOOD EPILEPSY; CANCER RADIOTHERAPY; CANCER SURGERY; CASE REPORT; CONFABULATION; DISEASE ASSOCIATION; DISORIENTATION; EPILEPTIC DISCHARGE; ERYTHROCYTE SEDIMENTATION RATE; FEMALE; FOLLOW UP; HUMAN; LABORATORY TEST; MEDIASTINUM METASTASIS; MIDDLE AGED; MINI MENTAL STATE EXAMINATION; MULTIMODALITY CANCER THERAPY; MYASTHENIA GRAVIS; NEUROIMAGING; NOTE; NUCLEAR MAGNETIC RESONANCE IMAGING; PLASMA EXCHANGE; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; THYMOMA; TREATMENT DURATION;

EID: 84964995898     PISSN: None     EISSN: 23327812     Source Type: Journal    
DOI: 10.1212/NXI.0000000000000073     Document Type: Note

References (7)

1. Petit-Pedrol M, Armangue T, Peng X, et al. Encephalitis with refractory seizures, status epilepticus, and antibodies to the GABAA receptor: a case series, characterisation of the antigen, and analysis of the effects of antibodies. Lancet Neurol 2014;13:276-286.
2. Lai M, Huijbers MG, Lancaster E, et al. Investigation of LGI1 as the antigen in limbic encephalitis previously attributed to potassium channels: a case series. Lancet Neurol 2010;9:776-285.
3. Evoli A, Lancaster E. Paraneoplastic disorders in thymoma patients. J Thorac Oncol 2014;9:S143-S147.
4. Ohkawa T, Satake S, Yokoi N, et al. Identification and characterization of GABA(A) receptor autoantibodies in autoimmune encephalitis. J Neurosci 2014;34:8151-8163.
5. Ohshita T, Kawakami H, Maruyama H, Kohriyama T, Arimura K, Matsumoto M. Voltage-gated potassium channel antibodies associated limbic encephalitis in a patient with invasive thymoma. J Neurol Sci 2006;250: 167-169.
6. Miyazaki Y, Hirayama M, Watanabe H, et al. Paraneoplas-tic encephalitis associated with myasthenia gravis and malignant thymoma. J Clin Neurosci 2012;19:336-338.
7. Evoli A, Lo Monaco M, Marra R, Lino MM, Batocchi AP, Tonali PA. Multiple paraneoplastic diseases associated with thymoma. Neuromuscul Disord 1999;9:601-603.