Post-surgical mediastinitis due to carbapenem-resistant Enterobacteriaceae: Clinical, epidemiological and survival characteristics

International Journal of Antimicrobial Agents

Volumn 47, Issue 5, 2016, Pages 386-390

  Abboud, C S ^a   Monteiro, J ^b   Stryjewski, M E ^c   Zandonadi, E C ^a   Barbosa, V ^a   Dantas, D ^a   Sousa, E E ^a   Fonseca, M J ^d   Jacobs, D M ^e   Pignatari, A C ^d   Kiffer, C ^d   Rao, G G ^e  

^a INSTITUTO DANTE PAZZANESE DE CARDIOLOGIA   (Brazil)

^b Clinical Microbiology Section   (Brazil)

^c CEMIC   (Argentina)

^d FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^e UNIVERSITY AT BUFFALO   (United States)

Author keywords

Carbapenem resistant Enterobacteriaceae; Mediastinitis; Polymyxin resistance; Post surgical infection

Indexed keywords

AMIKACIN; CARBAPENEM; CIPROFLOXACIN; COLISTIN; GENTAMICIN; IMIPENEM; MEROPENEM; POLYMYXIN B; TIGECYCLINE; ANTIINFECTIVE AGENT; CARBAPENEM DERIVATIVE; POLYMYXIN;

ADULT; AGED; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL GENE; BACTERIUM ISOLATE; BLA KPC GENE; BRAZIL; CARBAPENEM RESISTANT ENTEROBACTERIACEAE; CLINICAL FEATURE; COHORT ANALYSIS; DEBRIDEMENT; DRUG DOSE INCREASE; EPIDEMIOLOGICAL DATA; FEMALE; HEART SURGERY; HOSPITAL MORTALITY; HUMAN; IN VITRO STUDY; MAJOR CLINICAL STUDY; MALE; MEDIASTINITIS; MINIMUM INHIBITORY CONCENTRATION; MULTILOCUS SEQUENCE TYPING; PATHOGENESIS; POSTOPERATIVE INFECTION; PRIORITY JOURNAL; PULSED FIELD GEL ELECTROPHORESIS; RETROSPECTIVE STUDY; SURVIVAL RATE; DRUG EFFECTS; ENTEROBACTERIACEAE; ENTEROBACTERIACEAE INFECTIONS; ISOLATION AND PURIFICATION; MICROBIOLOGY; MIDDLE AGED; MORTALITY; SURGICAL WOUND INFECTION; SURVIVAL ANALYSIS; THORAX SURGERY;

AGED; ANTI-BACTERIAL AGENTS; BETA-LACTAM RESISTANCE; CARBAPENEMS; ENTEROBACTERIACEAE; ENTEROBACTERIACEAE INFECTIONS; FEMALE; HUMANS; MALE; MEDIASTINITIS; MIDDLE AGED; POLYMYXINS; RETROSPECTIVE STUDIES; SURGICAL WOUND INFECTION; SURVIVAL ANALYSIS; THORACIC SURGERY;

EID: 84964873462     PISSN: 09248579     EISSN: 18727913     Source Type: Journal    
DOI: 10.1016/j.ijantimicag.2016.02.015     Document Type: Article

References (22)

1. C.S. Abboud, S.B. Wey, and V.T. Baltar Risk factors for mediastinitis after cardiac surgery Ann Thorac Surg 77 2004 676 683
2. F. Filsoufi, J.G. Castillo, P.B. Rahmanian, S.R. Broumand, G. Silvay, A. Carpentier, and et al. Epidemiology of deep sternal wound infection in cardiac surgery J Cardiothorac Vasc Anesth 23 2009 488 494
3. F.D. Wang, and C.H. Chang Risk factors of deep sternal wound infections in coronary artery bypass graft surgery J Cardiovasc Surg (Torino) 41 2000 709 713
4. V.G. Fowler Jr., S.M. O'Brien, L.H. Muhlbaier, G.R. Corey, T.B. Ferguson, and E.D. Peterson Clinical predictors of major infections after cardiac surgery Circulation 112 9 Suppl. 2005 I358 I365
5. H. Charbonneau, J.M. Maillet, M. Faron, O. Mangin, E. Puymirat, P. Le Besnerais, and et al. Mediastinitis due to Gram-negative bacteria is associated with increased mortality Clin Microbiol Infect 20 2014 O197 O202
6. G.L. Daikos, S. Tsaousi, L.S. Tzouvelekis, I. Anyfantis, M. Psichogiou, A. Argyropoulou, and et al. Carbapenemase-producing Klebsiella pneumoniae bloodstream infections: lowering mortality by antibiotic combination schemes and the role of carbapenems Antimicrob Agents Chemother 58 2014 2322 2328
7. M. Tumbarello, P. Viale, C. Viscoli, E.M. Trecarichi, F. Tumietto, A. Marchese, and et al. Predictors of mortality in bloodstream infections caused by Klebsiella pneumoniae carbapenemase-producing K. pneumoniae: importance of combination therapy Clin Infect Dis 55 2012 943 950
8. M. Tumbarello, E.M. Trecarichi, F.G. De Rosa, M. Giannella, D.R. Giacobbe, M. Bassetti, and et al. Infections caused by KPC-producing Klebsiella pneumoniae: differences in therapy and mortality in a multicentre study J Antimicrob Chemother 70 2015 2133 2143
9. C. Mammina, C. Bonura, F. Di Bernardo, A. Aleo, T. Fasciana, C. Sodano, and et al. Ongoing spread of colistin-resistant Klebsiella pneumoniae in different wards of an acute general hospital, Italy, June to December 2011 Euro Surveill 2012 17 pii: 20248
10. D. Marchaim, T. Chopra, J.M. Pogue, F. Perez, A.M. Hujer, S. Rudin, and et al. Outbreak of colistin-resistant, carbapenem-resistant Klebsiella pneumoniae in metropolitan Detroit, Michigan Antimicrob Agents Chemother 55 2011 593 599
11. D.R. Giacobbe, V. Del Bono, E.M. Trecarichi, F.G. De Rosa, M. Giannella, M. Bassetti, and et al. Risk factors for bloodstream infections due to colistin-resistant KPC-producing Klebsiella pneumoniae: results from a multicenter case-control-control study Clin Microbiol Infect 21 2015 e1 e8
12. T.C. Horan, M. Andrus, and M.A. Dudeck CDC/NHSN surveillance definition of health care-associated infection and criteria for specific types of infections in the acute care setting Am J Infect Control 36 2008 309 332
13. J.G. Gaca, S. Sheng, M.A. Daneshmand, S. O'Brien, J.S. Rankin, J.M. Brennan, and et al. Outcomes for endocarditis surgery in North America: a simplified risk scoring system J Thorac Cardiovasc Surg 141 2011 98 106 e1-2
14. J. Monteiro, R.H. Widen, A.C. Pignatari, C. Kubasek, and S. Silbert Rapid detection of carbapenemase genes by multiplex real-time PCR J Antimicrob Chemother 67 2012 906 909
15. L. Diancourt, V. Passet, J. Verhoef, P.A. Grimont, and S. Brisse Multilocus sequence typing of Klebsiella pneumoniae nosocomial isolates J Clin Microbiol 43 2005 4178 4182
16. J.G. Egito, C.S. Abboud, A.P. Oliveira, C.A. Maximo, C.M. Montenegro, V.L. Amato, and et al. Clinical evolution of mediastinitis in patients undergoing adjuvant hyperbaric oxygen therapy after coronary artery bypass surgery Einstein (Sao Paulo) 11 2013 345 349
17. C.S. Abboud, J. Monteiro, J.I. Franca, A.C. Pignatari, E.E. De Souza, E.C. Camargo, and et al. A space-time model for carbapenemase-producing Klebsiella pneumoniae (KPC) cluster quantification in a high-complexity hospital Epidemiol Infect 143 2015 2648 2652
18. M.K. Hayden, M.Y. Lin, K. Lolans, S. Weiner, D. Blom, N.M. Moore, and et al. Prevention of colonization and infection by Klebsiella pneumoniae carbapenemase-producing Enterobacteriaceae in long-term acute-care hospitals Clin Infect Dis 60 2015 1153 1161
19. T. Ducomble, S. Faucheux, U. Helbig, U.X. Kaisers, B. Konig, A. Knaust, and et al. Large hospital outbreak of KPC-2-producing Klebsiella pneumoniae: investigating mortality and the impact of screening for KPC-2 with polymerase chain reaction J Hosp Infect 89 2015 179 185
20. Y. Carmeli, M. Akova, G. Cornaglia, G.L. Daikos, J. Garau, S. Harbarth, and et al. Controlling the spread of carbapenemase-producing Gram-negatives: therapeutic approach and infection control Clin Microbiol Infect 16 2010 102 111
21. F. Robicsek, H.K. Daugherty, and J.W. Cook The prevention and treatment of sternum separation following open-heart surgery J Thorac Cardiovasc Surg 73 1977 267 268
22. A.W. Yu, R.A. Rippel, E. Smock, and O.A. Jarral In patients with post-sternotomy mediastinitis is vacuum-assisted closure superior to conventional therapy? Interact Cardiovasc Thorac Surg 17 2013 861 865