메뉴 건너뛰기




Volumn 10, Issue 4, 2016, Pages

Behavioral Abnormalities in a Mouse Model of Chronic Toxoplasmosis Are Associated with MAG1 Antibody Levels and Cyst Burden

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN G; AMPHETAMINE; CENTRAL STIMULANT AGENT; PROTOZOON ANTIBODY;

EID: 84964854205     PISSN: 19352727     EISSN: 19352735     Source Type: Journal    
DOI: 10.1371/journal.pntd.0004674     Document Type: Article
Times cited : (38)

References (41)
  • 1
    • 84859609287 scopus 로고    scopus 로고
    • Globally diverse Toxoplasma gondii isolates comprise six major clades originating from a small number of distinct ancestral lineages
    • 22431627, . ().:–.
    • Su C, Khan A, Zhou P, Majumdar D, Ajzenberg D, et al. (2012) Globally diverse Toxoplasma gondii isolates comprise six major clades originating from a small number of distinct ancestral lineages. Proc Natl Acad Sci U S A109: 5844–5849. doi: 10.1073/pnas.120319010922431627
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 5844-5849
    • Su, C.1    Khan, A.2    Zhou, P.3    Majumdar, D.4    Ajzenberg, D.5
  • 2
    • 0028886480 scopus 로고
    • Toxoplasma gondii comprises three clonal lineages: correlation of parasite genotype with human disease
    • 7594717, ().:–.
    • Howe DK, Sibley LD, (1995) Toxoplasma gondii comprises three clonal lineages: correlation of parasite genotype with human disease. J Infect Dis172: 1561–1566. 7594717
    • (1995) J Infect Dis , vol.172 , pp. 1561-1566
    • Howe, D.K.1    Sibley, L.D.2
  • 3
    • 80054792189 scopus 로고    scopus 로고
    • Toxoplasma gondii effectors are master regulators of the inflammatory response
    • 21893432, ().:–.
    • Melo MB, Jensen KD, Saeij JP, (2011) Toxoplasma gondii effectors are master regulators of the inflammatory response. Trends Parasitol27: 487–495. doi: 10.1016/j.pt.2011.08.00121893432
    • (2011) Trends Parasitol , vol.27 , pp. 487-495
    • Melo, M.B.1    Jensen, K.D.2    Saeij, J.P.3
  • 4
    • 84924797808 scopus 로고    scopus 로고
    • Strain hypothesis of Toxoplasma gondii infection on the outcome of human diseases
    • ().:–.
    • Xiao J, Yolken RH, (2015) Strain hypothesis of Toxoplasma gondii infection on the outcome of human diseases. Acta Physiol (Oxf)213: 828–845.
    • (2015) Acta Physiol (Oxf) , vol.213 , pp. 828-845
    • Xiao, J.1    Yolken, R.H.2
  • 5
    • 30744475270 scopus 로고    scopus 로고
    • Genotyping of Toxoplasma gondii strains from immunocompromised patients reveals high prevalence of type I strains
    • 16333071, . ().:–.
    • Khan A, Su C, German M, Storch GA, Clifford DB, et al. (2005) Genotyping of Toxoplasma gondii strains from immunocompromised patients reveals high prevalence of type I strains. J Clin Microbiol43: 5881–5887. 16333071
    • (2005) J Clin Microbiol , vol.43 , pp. 5881-5887
    • Khan, A.1    Su, C.2    German, M.3    Storch, G.A.4    Clifford, D.B.5
  • 6
    • 37349130556 scopus 로고    scopus 로고
    • Toxoplasma gondii: genotyping of strains from Brazilian AIDS patients with cerebral toxoplasmosis by multilocus PCR-RFLP markers
    • 17950282, . ().:–.
    • Ferreira IM, Vidal JE, Costa-Silva TA, Meira CS, Hiramoto RM, et al. (2008) Toxoplasma gondii: genotyping of strains from Brazilian AIDS patients with cerebral toxoplasmosis by multilocus PCR-RFLP markers. Exp Parasitol118: 221–227. 17950282
    • (2008) Exp Parasitol , vol.118 , pp. 221-227
    • Ferreira, I.M.1    Vidal, J.E.2    Costa-Silva, T.A.3    Meira, C.S.4    Hiramoto, R.M.5
  • 7
    • 0035450774 scopus 로고    scopus 로고
    • Unusual abundance of atypical strains associated with human ocular toxoplasmosis
    • 11474426, ().:–.
    • Grigg ME, Ganatra J, Boothroyd JC, Margolis TP, (2001) Unusual abundance of atypical strains associated with human ocular toxoplasmosis. J Infect Dis184: 633–639. 11474426
    • (2001) J Infect Dis , vol.184 , pp. 633-639
    • Grigg, M.E.1    Ganatra, J.2    Boothroyd, J.C.3    Margolis, T.P.4
  • 8
    • 70349759316 scopus 로고    scopus 로고
    • Serological pattern consistent with infection with type I Toxoplasma gondii in mothers and risk of psychosis among adult offspring
    • 19638313, . ().:–.
    • Xiao J, Buka SL, Cannon TD, Suzuki Y, Viscidi RP, et al. (2009) Serological pattern consistent with infection with type I Toxoplasma gondii in mothers and risk of psychosis among adult offspring. Microbes Infect11: 1011–1018. doi: 10.1016/j.micinf.2009.07.00719638313
    • (2009) Microbes Infect , vol.11 , pp. 1011-1018
    • Xiao, J.1    Buka, S.L.2    Cannon, T.D.3    Suzuki, Y.4    Viscidi, R.P.5
  • 9
    • 84861085007 scopus 로고    scopus 로고
    • Prematurity and severity are associated with Toxoplasma gondii alleles (NCCCTS, 1981–2009)
    • 22499837, . ().:–.
    • McLeod R, Boyer KM, Lee D, Mui E, Wroblewski K, et al. (2012) Prematurity and severity are associated with Toxoplasma gondii alleles (NCCCTS, 1981–2009). Clin Infect Dis54: 1595–1605. doi: 10.1093/cid/cis25822499837
    • (2012) Clin Infect Dis , vol.54 , pp. 1595-1605
    • McLeod, R.1    Boyer, K.M.2    Lee, D.3    Mui, E.4    Wroblewski, K.5
  • 10
    • 19144362194 scopus 로고    scopus 로고
    • Evidence for genetic regulation of susceptibility to toxoplasmic encephalitis in AIDS patients
    • 8537674, . ().:–.
    • Suzuki Y, Wong SY, Grumet FC, Fessel J, Montoya JG, et al. (1996) Evidence for genetic regulation of susceptibility to toxoplasmic encephalitis in AIDS patients. J Infect Dis173: 265–268. 8537674
    • (1996) J Infect Dis , vol.173 , pp. 265-268
    • Suzuki, Y.1    Wong, S.Y.2    Grumet, F.C.3    Fessel, J.4    Montoya, J.G.5
  • 11
    • 12144286439 scopus 로고    scopus 로고
    • Usefulness of quantitative polymerase chain reaction in amniotic fluid as early prognostic marker of fetal infection with Toxoplasma gondii
    • 15042017, . ().:–.
    • Romand S, Chosson M, Franck J, Wallon M, Kieffer F, et al. (2004) Usefulness of quantitative polymerase chain reaction in amniotic fluid as early prognostic marker of fetal infection with Toxoplasma gondii. Am J Obstet Gynecol190: 797–802. 15042017
    • (2004) Am J Obstet Gynecol , vol.190 , pp. 797-802
    • Romand, S.1    Chosson, M.2    Franck, J.3    Wallon, M.4    Kieffer, F.5
  • 12
    • 65349159878 scopus 로고    scopus 로고
    • Severe acquired toxoplasmosis caused by wild cycle of Toxoplasma gondii, French Guiana
    • 19331765, ().:–.
    • Carme B, Demar M, Ajzenberg D, Darde ML, (2009) Severe acquired toxoplasmosis caused by wild cycle of Toxoplasma gondii, French Guiana. Emerg Infect Dis15: 656–658. doi: 10.3201/eid1504.08130619331765
    • (2009) Emerg Infect Dis , vol.15 , pp. 656-658
    • Carme, B.1    Demar, M.2    Ajzenberg, D.3    Darde, M.L.4
  • 13
    • 84871738330 scopus 로고    scopus 로고
    • The Toxoplasma MAG1 peptides induce sex-based humoral immune response in mice and distinguish active from chronic human infection
    • 23142034, . ().:–.
    • Xiao J, Viscidi RP, Kannan G, Pletnikov MV, Li Y, et al. (2013) The Toxoplasma MAG1 peptides induce sex-based humoral immune response in mice and distinguish active from chronic human infection. Microbes Infect15: 74–83. doi: 10.1016/j.micinf.2012.10.01623142034
    • (2013) Microbes Infect , vol.15 , pp. 74-83
    • Xiao, J.1    Viscidi, R.P.2    Kannan, G.3    Pletnikov, M.V.4    Li, Y.5
  • 14
    • 57149129975 scopus 로고    scopus 로고
    • Neurological and behavioral abnormalities, ventricular dilatation, altered cellular functions, inflammation, and neuronal injury in brains of mice due to common, persistent, parasitic infection
    • 18947414, . ().:.
    • Hermes G, Ajioka JW, Kelly KA, Mui E, Roberts F, et al. (2008) Neurological and behavioral abnormalities, ventricular dilatation, altered cellular functions, inflammation, and neuronal injury in brains of mice due to common, persistent, parasitic infection. J Neuroinflammation5: 48. doi: 10.1186/1742-2094-5-4818947414
    • (2008) J Neuroinflammation , vol.5 , pp. 48
    • Hermes, G.1    Ajioka, J.W.2    Kelly, K.A.3    Mui, E.4    Roberts, F.5
  • 15
    • 84857651673 scopus 로고    scopus 로고
    • Sex-specific changes in gene expression and behavior induced by chronic Toxoplasma infection in mice
    • 22240252, . ().:–.
    • Xiao J, Kannan G, Jones-Brando L, Brannock C, Krasnova IN, et al. (2012) Sex-specific changes in gene expression and behavior induced by chronic Toxoplasma infection in mice. Neuroscience206: 39–48. doi: 10.1016/j.neuroscience.2011.12.05122240252
    • (2012) Neuroscience , vol.206 , pp. 39-48
    • Xiao, J.1    Kannan, G.2    Jones-Brando, L.3    Brannock, C.4    Krasnova, I.N.5
  • 17
    • 33746433950 scopus 로고    scopus 로고
    • Cycloxygenase-2 activity promotes cognitive deficits but not increased amyloid burden in a model of Alzheimer's disease in a sex-dimorphic pattern
    • 16753269, . ().:–.
    • Melnikova T, Savonenko A, Wang Q, Liang X, Hand T, et al. (2006) Cycloxygenase-2 activity promotes cognitive deficits but not increased amyloid burden in a model of Alzheimer's disease in a sex-dimorphic pattern. Neuroscience141: 1149–1162. 16753269
    • (2006) Neuroscience , vol.141 , pp. 1149-1162
    • Melnikova, T.1    Savonenko, A.2    Wang, Q.3    Liang, X.4    Hand, T.5
  • 18
    • 84909952376 scopus 로고    scopus 로고
    • Chlorovirus ATCV-1 is part of the human oropharyngeal virome and is associated with changes in cognitive functions in humans and mice
    • 25349393, . ().:–.
    • Yolken RH, Jones-Brando L, Dunigan DD, Kannan G, Dickerson F, et al. (2014) Chlorovirus ATCV-1 is part of the human oropharyngeal virome and is associated with changes in cognitive functions in humans and mice. Proc Natl Acad Sci U S A111: 16106–16111. doi: 10.1073/pnas.141889511125349393
    • (2014) Proc Natl Acad Sci U S A , vol.111 , pp. 16106-16111
    • Yolken, R.H.1    Jones-Brando, L.2    Dunigan, D.D.3    Kannan, G.4    Dickerson, F.5
  • 19
    • 84897529575 scopus 로고    scopus 로고
    • MicroRNA-132 dysregulation in Toxoplasma gondii infection has implications for dopamine signaling pathway
    • 24657774, . ().:–.
    • Xiao J, Li Y, Prandovszky E, Karuppagounder SS, Talbot CC, Jr.et al. (2014) MicroRNA-132 dysregulation in Toxoplasma gondii infection has implications for dopamine signaling pathway. Neuroscience268: 128–138. doi: 10.1016/j.neuroscience.2014.03.01524657774
    • (2014) Neuroscience , vol.268 , pp. 128-138
    • Xiao, J.1    Li, Y.2    Prandovszky, E.3    Karuppagounder, S.S.4    Talbot, C.C.5
  • 20
    • 57049133444 scopus 로고    scopus 로고
    • Toxoplasma gondii: Identification and characterization of bradyzoite-specific deoxyribose phosphate aldolase-like gene (TgDPA)
    • 18950626, . ().:–.
    • Ueno A, Dautu G, Munyaka B, Carmen G, Kobayashi Y, et al. (2009) Toxoplasma gondii: Identification and characterization of bradyzoite-specific deoxyribose phosphate aldolase-like gene (TgDPA). Exp Parasitol121: 55–63. doi: 10.1016/j.exppara.2008.09.01818950626
    • (2009) Exp Parasitol , vol.121 , pp. 55-63
    • Ueno, A.1    Dautu, G.2    Munyaka, B.3    Carmen, G.4    Kobayashi, Y.5
  • 21
    • 28444488928 scopus 로고    scopus 로고
    • Toxoplasma gondii-specific immunoglobulin M limits parasite dissemination by preventing host cell invasion
    • 16299300, ().:–.
    • Couper KN, Roberts CW, Brombacher F, Alexander J, Johnson LL, (2005) Toxoplasma gondii-specific immunoglobulin M limits parasite dissemination by preventing host cell invasion. Infect Immun73: 8060–8068. 16299300
    • (2005) Infect Immun , vol.73 , pp. 8060-8068
    • Couper, K.N.1    Roberts, C.W.2    Brombacher, F.3    Alexander, J.4    Johnson, L.L.5
  • 22
    • 62849121535 scopus 로고    scopus 로고
    • A unique dual activity amino acid hydroxylase in Toxoplasma gondii
    • 19277211, ().:.
    • Gaskell EA, Smith JE, Pinney JW, Westhead DR, McConkey GA, (2009) A unique dual activity amino acid hydroxylase in Toxoplasma gondii. PLoS One4: e4801. doi: 10.1371/journal.pone.000480119277211
    • (2009) PLoS One , vol.4 , pp. e4801
    • Gaskell, E.A.1    Smith, J.E.2    Pinney, J.W.3    Westhead, D.R.4    McConkey, G.A.5
  • 23
    • 84871222839 scopus 로고    scopus 로고
    • Toxoplasma gondii infection and behaviour—location, location, location?
    • 23225873, ():–.
    • McConkey GA, Martin HL, Bristow GC, Webster JP, (2013) Toxoplasma gondii infection and behaviour—location, location, location?J Exp Biol216: 113–119. doi: 10.1242/jeb.07415323225873
    • (2013) J Exp Biol , vol.216 , pp. 113-119
    • McConkey, G.A.1    Martin, H.L.2    Bristow, G.C.3    Webster, J.P.4
  • 24
    • 84911380811 scopus 로고    scopus 로고
    • Chronic infection of Toxoplasma gondii downregulates miR-132 expression in multiple brain regions in a sex-dependent manner
    • 25351997, ().:–.
    • Li YE, Kannan G, Pletnikov MV, Yolken RH, Xiao J, (2015) Chronic infection of Toxoplasma gondii downregulates miR-132 expression in multiple brain regions in a sex-dependent manner. Parasitology142: 623–632. doi: 10.1017/S003118201400167X25351997
    • (2015) Parasitology , vol.142 , pp. 623-632
    • Li, Y.E.1    Kannan, G.2    Pletnikov, M.V.3    Yolken, R.H.4    Xiao, J.5
  • 25
    • 84862174920 scopus 로고    scopus 로고
    • miR-212/132 expression and functions: within and beyond the neuronal compartment
    • 22362752, ().:–.
    • Wanet A, Tacheny A, Arnould T, Renard P, (2012) miR-212/132 expression and functions: within and beyond the neuronal compartment. Nucleic Acids Res40: 4742–4753. doi: 10.1093/nar/gks15122362752
    • (2012) Nucleic Acids Res , vol.40 , pp. 4742-4753
    • Wanet, A.1    Tacheny, A.2    Arnould, T.3    Renard, P.4
  • 26
    • 0036861363 scopus 로고    scopus 로고
    • Toxoplasma gondii MAG1 protein expression
    • 12473362, ().:.
    • Ferguson DJ, Parmley SF, (2002) Toxoplasma gondii MAG1 protein expression. Trends Parasitol18: 482. 12473362
    • (2002) Trends Parasitol , vol.18 , pp. 482
    • Ferguson, D.J.1    Parmley, S.F.2
  • 28
    • 84885410594 scopus 로고    scopus 로고
    • Toxoplasma serotype is associated with development of ocular toxoplasmosis
    • 23878321, . ().:–.
    • Shobab L, Pleyer U, Johnsen J, Metzner S, James ER, et al. (2013) Toxoplasma serotype is associated with development of ocular toxoplasmosis. J Infect Dis208: 1520–1528. doi: 10.1093/infdis/jit31323878321
    • (2013) J Infect Dis , vol.208 , pp. 1520-1528
    • Shobab, L.1    Pleyer, U.2    Johnsen, J.3    Metzner, S.4    James, E.R.5
  • 29
    • 84880644407 scopus 로고    scopus 로고
    • Atypical strain of Toxoplasma gondii causing fatal reactivation after hematopoietic stem cell transplantion in a patient with an underlying immunological deficiency
    • 23761151, . ().:–.
    • Stajner T, Vasiljevic Z, Vujic D, Markovic M, Ristic G, et al. (2013) Atypical strain of Toxoplasma gondii causing fatal reactivation after hematopoietic stem cell transplantion in a patient with an underlying immunological deficiency. J Clin Microbiol51: 2686–2690. doi: 10.1128/JCM.01077-1323761151
    • (2013) J Clin Microbiol , vol.51 , pp. 2686-2690
    • Stajner, T.1    Vasiljevic, Z.2    Vujic, D.3    Markovic, M.4    Ristic, G.5
  • 30
    • 77954428737 scopus 로고    scopus 로고
    • Correlation of parasite load determined by quantitative PCR to clinical outcome in a heart transplant patient with disseminated toxoplasmosis
    • 20463167, . ().:–.
    • Patrat-Delon S, Gangneux JP, Lavoue S, Lelong B, Guiguen C, et al. (2010) Correlation of parasite load determined by quantitative PCR to clinical outcome in a heart transplant patient with disseminated toxoplasmosis. J Clin Microbiol48: 2541–2545. doi: 10.1128/JCM.00252-1020463167
    • (2010) J Clin Microbiol , vol.48 , pp. 2541-2545
    • Patrat-Delon, S.1    Gangneux, J.P.2    Lavoue, S.3    Lelong, B.4    Guiguen, C.5
  • 31
    • 33744508690 scopus 로고    scopus 로고
    • Parasites as causative agents of human affective disorders? The impact of anti-psychotic, mood-stabilizer and anti-parasite medication on Toxoplasma gondii's ability to alter host behaviour
    • 16627289, ().:–.
    • Webster JP, Lamberton PH, Donnelly CA, Torrey EF, (2006) Parasites as causative agents of human affective disorders? The impact of anti-psychotic, mood-stabilizer and anti-parasite medication on Toxoplasma gondii's ability to alter host behaviour. Proc Biol Sci273: 1023–1030. 16627289
    • (2006) Proc Biol Sci , vol.273 , pp. 1023-1030
    • Webster, J.P.1    Lamberton, P.H.2    Donnelly, C.A.3    Torrey, E.F.4
  • 32
    • 33750315422 scopus 로고    scopus 로고
    • The role of dopamine in Toxoplasma-induced behavioural alterations in mice: an ethological and ethopharmacological study
    • 16882355, ().:–.
    • Skallova A, Kodym P, Frynta D, Flegr J, (2006) The role of dopamine in Toxoplasma-induced behavioural alterations in mice: an ethological and ethopharmacological study. Parasitology133: 525–535. 16882355
    • (2006) Parasitology , vol.133 , pp. 525-535
    • Skallova, A.1    Kodym, P.2    Frynta, D.3    Flegr, J.4
  • 33
    • 84870562259 scopus 로고    scopus 로고
    • Sex-dependent neurotransmitter level changes in brains of Toxoplasma gondii infected mice
    • 23098668, ().:–.
    • Gatkowska J, Wieczorek M, Dziadek B, Dzitko K, Dlugonska H, (2013) Sex-dependent neurotransmitter level changes in brains of Toxoplasma gondii infected mice. Exp Parasitol133: 1–7. doi: 10.1016/j.exppara.2012.10.00523098668
    • (2013) Exp Parasitol , vol.133 , pp. 1-7
    • Gatkowska, J.1    Wieczorek, M.2    Dziadek, B.3    Dzitko, K.4    Dlugonska, H.5
  • 34
    • 84923006085 scopus 로고    scopus 로고
    • Reassessment of the role of aromatic amino acid hydroxylases and the effect of infection by Toxoplasma gondii on host dopamine
    • 25547791, ().:–.
    • Wang ZT, Harmon S, O'Malley KL, Sibley LD, (2015) Reassessment of the role of aromatic amino acid hydroxylases and the effect of infection by Toxoplasma gondii on host dopamine. Infect Immun83: 1039–1047. doi: 10.1128/IAI.02465-1425547791
    • (2015) Infect Immun , vol.83 , pp. 1039-1047
    • Wang, Z.T.1    Harmon, S.2    O'Malley, K.L.3    Sibley, L.D.4
  • 35
    • 0018614103 scopus 로고
    • Learning capacity and memory of normal and Toxoplasma-infected laboratory rats and mice
    • 543216, ().:–.
    • Witting PA, (1979) Learning capacity and memory of normal and Toxoplasma-infected laboratory rats and mice. Z Parasitenkd61: 29–51. 543216
    • (1979) Z Parasitenkd , vol.61 , pp. 29-51
    • Witting, P.A.1
  • 36
    • 34248391475 scopus 로고    scopus 로고
    • Higher perceived dominance in Toxoplasma infected men—a new evidence for role of increased level of testosterone in toxoplasmosis-associated changes in human behavior
    • 17435678, ().:–.
    • Hodkova H, Kolbekova P, Skallova A, Lindova J, Flegr J, (2007) Higher perceived dominance in Toxoplasma infected men—a new evidence for role of increased level of testosterone in toxoplasmosis-associated changes in human behavior. Neuro Endocrinol Lett28: 110–114. 17435678
    • (2007) Neuro Endocrinol Lett , vol.28 , pp. 110-114
    • Hodkova, H.1    Kolbekova, P.2    Skallova, A.3    Lindova, J.4    Flegr, J.5
  • 37
    • 77953289787 scopus 로고    scopus 로고
    • Acquired infection with Toxoplasma gondii in adult mice results in sensorimotor deficits but normal cognitive behavior despite widespread brain pathology
    • 20348009, . ().:–.
    • Gulinello M, Acquarone M, Kim JH, Spray DC, Barbosa HS, et al. (2010) Acquired infection with Toxoplasma gondii in adult mice results in sensorimotor deficits but normal cognitive behavior despite widespread brain pathology. Microbes Infect12: 528–537. doi: 10.1016/j.micinf.2010.03.00920348009
    • (2010) Microbes Infect , vol.12 , pp. 528-537
    • Gulinello, M.1    Acquarone, M.2    Kim, J.H.3    Spray, D.C.4    Barbosa, H.S.5
  • 38
    • 78649739197 scopus 로고    scopus 로고
    • Transgenic miR132 alters neuronal spine density and impairs novel object recognition memory
    • 21124738, ().:.
    • Hansen KF, Sakamoto K, Wayman GA, Impey S, Obrietan K, (2010) Transgenic miR132 alters neuronal spine density and impairs novel object recognition memory. PLoS One5: e15497. doi: 10.1371/journal.pone.001549721124738
    • (2010) PLoS One , vol.5 , pp. e15497
    • Hansen, K.F.1    Sakamoto, K.2    Wayman, G.A.3    Impey, S.4    Obrietan, K.5
  • 39
    • 84879552488 scopus 로고    scopus 로고
    • miRNA-132: a dynamic regulator of cognitive capacity
    • 22706759, . ().:–.
    • Hansen KF, Karelina K, Sakamoto K, Wayman GA, Impey S, et al. (2013) miRNA-132: a dynamic regulator of cognitive capacity. Brain Struct Funct218: 817–831. doi: 10.1007/s00429-012-0431-422706759
    • (2013) Brain Struct Funct , vol.218 , pp. 817-831
    • Hansen, K.F.1    Karelina, K.2    Sakamoto, K.3    Wayman, G.A.4    Impey, S.5
  • 40
    • 0034131525 scopus 로고    scopus 로고
    • Discrimination between patients with acquired toxoplasmosis and congenital toxoplasmosis on the basis of the immune response to parasite antigens
    • 10837184, . ().:–.
    • Yamamoto JH, Vallochi AL, Silveira C, Filho JK, Nussenblatt RB, et al. (2000) Discrimination between patients with acquired toxoplasmosis and congenital toxoplasmosis on the basis of the immune response to parasite antigens. J Infect Dis181: 2018–2022. 10837184
    • (2000) J Infect Dis , vol.181 , pp. 2018-2022
    • Yamamoto, J.H.1    Vallochi, A.L.2    Silveira, C.3    Filho, J.K.4    Nussenblatt, R.B.5
  • 41
    • 84888211861 scopus 로고    scopus 로고
    • Severe South American ocular toxoplasmosis is associated with decreased Ifn-gamma/Il-17a and increased Il-6/Il-13 intraocular levels
    • 24278490, . ().:.
    • de-la-Torre A, Sauer A, Pfaff AW, Bourcier T, Brunet J, et al. (2013) Severe South American ocular toxoplasmosis is associated with decreased Ifn-gamma/Il-17a and increased Il-6/Il-13 intraocular levels. PLoS Negl Trop Dis7: e2541. doi: 10.1371/journal.pntd.000254124278490
    • (2013) PLoS Negl Trop Dis , vol.7 , pp. e2541
    • de-la-Torre, A.1    Sauer, A.2    Pfaff, A.W.3    Bourcier, T.4    Brunet, J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.