Stress-induced gene expression and behavior are controlled by DNA methylation and methyl donor availability in the dentate gyrus

Proceedings of the National Academy of Sciences of the United States of America

Volumn 113, Issue 17, 2016, Pages 4830-4835

  Saunderson, Emily A ^a,d   Spiers, Helen ^b   Mifsud, Karen R ^a   Gutierrez Mecinas, Maria ^a,e   Trollope, Alexandra F ^a,f   Shaikh, Abeera ^a   Mill, Jonathan ^b,c   Reul, Johannes M H M ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b KING'S COLLEGE LONDON   (United Kingdom)

^c UNIVERSITY OF EXETER MEDICAL SCHOOL   (United Kingdom)

^d QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^e UNIVERSITY OF GLASGOW   (United Kingdom)

^f JAMES COOK UNIVERSITY   (Australia)

Author keywords

Behavior; DNA methylation; Hippocampus; Immediate early gene; Stress

Indexed keywords

DNA; DNA METHYLTRANSFERASE 1; DNA METHYLTRANSFERASE 3A; DNA METHYLTRANSFERASE 3B; EARLY GROWTH RESPONSE FACTOR 1; HISTONE H3; LYSINE; MESSENGER RNA; PROTEIN C FOS; S ADENOSYLMETHIONINE; DNA (CYTOSINE 5) METHYLTRANSFERASE; EGR1 PROTEIN, RAT;

ANIMAL TISSUE; BEHAVIOR; BRAIN NERVE CELL; CONFERENCE PAPER; CONTROLLED STUDY; CPG ISLAND; DENTATE GYRUS; DNA METHYLATION; EPIGENETICS; GENE ACTIVITY; GENE EXPRESSION; GENE LOCUS; GENETIC ASSOCIATION; HIPPOCAMPUS; HISTONE METHYLATION; HISTONE MODIFICATION; IMMEDIATE EARLY GENE; IN VITRO STUDY; MALE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; RAT; STRESS; TRANSCRIPTION INITIATION SITE; UNTRANSLATED REGION; ANIMAL; CATALEPSY; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; HISTONE CODE; MENTAL STRESS; METABOLISM; ONCOGENE; PHYSIOLOGICAL STRESS; SWIMMING; WISTAR RAT;

ANIMALS; CPG ISLANDS; DENTATE GYRUS; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DNA METHYLATION; EARLY GROWTH RESPONSE PROTEIN 1; FREEZING REACTION, CATALEPTIC; GENE EXPRESSION REGULATION; GENES, FOS; GENES, IMMEDIATE-EARLY; HISTONE CODE; MALE; PROMOTER REGIONS, GENETIC; RATS; RATS, WISTAR; S-ADENOSYLMETHIONINE; STRESS, PHYSIOLOGICAL; STRESS, PSYCHOLOGICAL; SWIMMING;

EID: 84964780421     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1524857113     Document Type: Article

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