Association between RASSF1A promoter methylation and renal cell cancer susceptibility: A meta-analysis

Genetics and Molecular Research

Volumn 15, Issue 2, 2016, Pages

  Huang, Y Q ^a   Guan, H ^a   Liu, C H ^a   Liu, D C ^a,b   Xu, B ^a   Jiang, L ^a   Lin, Z X ^a   Chen, M ^a  

^a SOUTHEAST UNIVERSITY   (China)

^b XUZHOU CENTRAL HOSPITAL   (China)

Author keywords

Meta analysis; Methylation; Promoter; RASSF1A; Renal cell cancer

Indexed keywords

RAS ASSOCIATION DOMAIN FAMILY PROTEIN 1A; RASSF1 PROTEIN, HUMAN; TUMOR SUPPRESSOR PROTEIN;

ADVANCED CANCER; ARTICLE; CANCER GRADING; CANCER GROWTH; CANCER PROGNOSIS; CANCER RISK; CANCER STAGING; CANCER SUSCEPTIBILITY; CLEAR CELL CARCINOMA; CLINICAL FEATURE; CPG ISLAND; EPIGENETICS; HUMAN; KIDNEY CARCINOMA; MAJOR CLINICAL STUDY; META ANALYSIS; METHYLATION; NEPHROBLASTOMA; ONCOCYTOMA; PROMOTER REGION; DNA METHYLATION; GENETIC ASSOCIATION STUDY; GENETIC PREDISPOSITION; GENETICS; PATHOLOGY;

CARCINOMA, RENAL CELL; DNA METHYLATION; GENETIC ASSOCIATION STUDIES; GENETIC PREDISPOSITION TO DISEASE; HUMANS; PROMOTER REGIONS, GENETIC; TUMOR SUPPRESSOR PROTEINS;

EID: 84964754216     PISSN: None     EISSN: 16765680     Source Type: Journal    
DOI: 10.4238/gmr.15026994     Document Type: Article

References (35)

1. Abouzeid HE, Kassem AM, Abdel Wahab AH, El-mezayen HA, et al. (2011). Promoter hypermethylation of RASSF1A, MGMT, and HIC-1 genes in benign and malignant colorectal tumors. Tumour Biol. 32: 845-852. http://dx.doi.org/10.1007/s13277-011-0206-1
2. Bilgrami SM, Qureshi SA, Pervez S and Abbas F (2014). Promoter hypermethylation of tumor suppressor genes correlates with tumor grade and invasiveness in patients with urothelial bladder cancer. Springerplus 3: 178. http://dx.doi.org/10.1186/2193-1801-3-178
3. Chen M, Zhou ZY, Chen JG, Tong N, et al. (2014). Effect of miR-146a polymorphism on biochemical recurrence risk after radical prostatectomy in southern Chinese population. Genet. Mol. Res. 13: 10615-10621. http://dx.doi.org/10.4238/2014.December.18.3
4. Cong DG, Wang SF and Zhang TW (2006). [mRNA expression of RASSF1A in esophageal squamous cell carcinoma and clinical significance thereof]. Zhonghua Yi Xue Za Zhi 86: 1624-1627.
5. Costa VL, Henrique R, Ribeiro FR, Pinto M, et al. (2007). Quantitative promoter methylation analysis of multiple cancer- related genes in renal cell tumors. BMC Cancer 7: 133. http://dx.doi.org/10.1186/1471-2407-7-133
6. Duan Jianmin LZZM (2007). Aberrant methylation promoter of RASSF1A and BLU genes in RCC tissues. Acad. J. Sec. Mil. Med. Univ. 10: 1068-1071.
7. Dulaimi E, Ibanez de Caceres I, Uzzo RG, Al-Saleem T, et al. (2004). Promoter hypermethylation profile of kidney cancer. Clin. Cancer Res. 10: 3972-3979. http://dx.doi.org/10.1158/1078-0432.CCR-04-0175
8. Eads CA, Danenberg KD, Kawakami K, Saltz LB, et al. (2000). MethyLight: a high-throughput assay to measure DNA methylation. Nucleic Acids Res. 28: E32. http://dx.doi.org/10.1093/nar/28.8.e32
9. Ehrlich M, Jiang G, Fiala E, Dome JS, et al. (2002). Hypomethylation and hypermethylation of DNA in Wilms tumors. Oncogene 21: 6694-6702. http://dx.doi.org/10.1038/sj.onc.1205890
10. Ellinger J, Holl D, Nuhn P, Kahl P, et al. (2011). DNA hypermethylation in papillary renal cell carcinoma. BJU Int. 107: 664-669. http://dx.doi.org/10.1111/j.1464-410X.2010.09468.x
11. Gonzalgo ML, Yegnasubramanian S, Yan G, Rogers CG, et al. (2004). Molecular profiling and classification of sporadic renal cell carcinoma by quantitative methylation analysis. Clin. Cancer Res. 10: 7276-7283. http://dx.doi.org/10.1158/1078-0432.CCR-03-0692
12. Guida FM, Santoni M, Conti A, Burattini L, et al. (2014). Alternative dosing schedules for sunitinib as a treatment of patients with metastatic renal cell carcinoma. Crit. Rev. Oncol. Hematol. 92: 208-217. http://dx.doi.org/10.1016/j.critrevonc.2014.07.006
13. Harada K, Toyooka S, Maitra A, Maruyama R, et al. (2002). Aberrant promoter methylation and silencing of the RASSF1A gene in pediatric tumors and cell lines. Oncogene 21: 4345-4349. http://dx.doi.org/10.1038/sj.onc.1205446
14. Kawai Y, Sakano S, Suehiro Y, Okada T, et al. (2010). Methylation level of the RASSF1A promoter is an independent prognostic factor for clear-cell renal cell carcinoma. Ann. Oncol. 21: 1612-1617. http://dx.doi.org/10.1093/annonc/mdp577
15. Kristensen LS, Mikeska T, Krypuy M and Dobrovic A (2008). Sensitive Melting Analysis after Real Time- Methylation Specific PCR (SMART-MSP): high-throughput and probe-free quantitative DNA methylation detection. Nucleic Acids Res. 36: e42. http://dx.doi.org/10.1093/nar/gkn113
16. Kriston L (2013). Dealing with clinical heterogeneity in meta-analysis. Assumptions, methods, interpretation. Int. J. Methods Psychiatr. Res. 22: 1-15. http://dx.doi.org/10.1002/mpr.1377
17. Lee VH, Chow BK, Lo KW, Chow LS, et al. (2009). Regulation of RASSF1A in nasopharyngeal cells and its response to UV irradiation. Gene 443: 55-63. http://dx.doi.org/10.1016/j.gene.2009.05.003
18. Loginov VI, Maliukova AV, Seregin IuA, Khodyrev DS, et al. (2004). [Methylation of the promoter region of the RASSF1A gene, a candidate tumor suppressor, in primary epithelial tumors]. Mol. Biol. (Mosk.) 38: 654-667
19. Mengxi D, Qian W, Nan W, Xiaoguang X, et al. (2013). Effect of DNA methylation inhibitor on RASSF1A genes expression in non-small cell lung cancer cell line A549 and A549DDP. Cancer Cell Int. 13: 91. http://dx.doi.org/10.1186/1475-2867-13-91
20. Morrissey C, Martinez A, Zatyka M, Agathanggelou A, et al. (2001). Epigenetic inactivation of the RASSF1A 3p21.3 tumor suppressor gene in both clear cell and papillary renal cell carcinoma. Cancer Res. 61: 7277-7281.
21. Ohshima J, Haruta M, Fujiwara Y, Watanabe N, et al. (2012). Methylation of the RASSF1A promoter is predictive of poor outcome among patients with Wilms tumor. Pediatr. Blood Cancer 59: 499-505. http://dx.doi.org/10.1002/pbc.24093
22. Peters I, Rehmet K, Wilke N, Kuczyk MA, et al. (2007). RASSF1A promoter methylation and expression analysis in normal and neoplastic kidney indicates a role in early tumorigenesis. Mol. Cancer 6: 49. http://dx.doi.org/10.1186/1476-4598-6-49
23. Pronina IV, Loginov VI, Kholdyrev DS, Kazubskaia TP, et al. (2012). [Alterations of expression level of RASSFIA gene in primary epithelial tumors of various locations]. Mol. Biol. (Mosk.) 46: 260-268.
24. Ram RR, Mendiratta S, Bodemann BO, Torres MJ, et al. (2014). RASSF1A inactivation unleashes a tumor suppressor/ oncogene cascade with context-dependent consequences on cell cycle progression. Mol. Cell. Biol. 34: 2350-2358. http://dx.doi.org/10.1128/MCB.01506-13
25. Sebova K, Zmetakova I, Bella V, Kajo K, et al. (2011-2012). RASSF1A and CDH1 hypermethylation as potential epimarkers in breast cancer. Cancer Biomark. 10: 13-26.
26. Serth J, Tezval H, Peters I, Atschekzei F, et al. (2008). Methylation of the RASSF1A tumor suppressor gene promoter. Risk factor for carcinogenesis of urological tumors. Urologe A 47: 1117-1118, 1120-1121.
27. Siegel R, Desantis C and Jemal A (2014). Colorectal cancer statistics, 2014. CA Cancer J. Clin. 64: 104-117. http://dx.doi.org/10.3322/caac.21220
28. Tokinaga K, Okuda H, Nomura A, Ashida S, et al. (2004). Hypermethylation of the RASSF1A tumor suppressor gene in Japanese clear cell renal cell carcinoma. Oncol. Rep. 12: 805-810.
29. Wagner KJ, Cooper WN, Grundy RG, Caldwell G, et al. (2002). Frequent RASSF1A tumour suppressor gene promoter methylation in Wilms’ tumour and colorectal cancer. Oncogene 21: 7277-7282. http://dx.doi.org/10.1038/sj.onc.1205922
30. Wang Dan ZJMZ (2009). Discussing on the research of heterogeneity in meta-analysis. Chin. J. Evidence-Based Med. 1115-1118.
31. Xu B, Tong N, Chen SQ, Yang Y, et al. (2012). Contribution of HOGG1 Ser³²⁶Cys polymorphism to the development of prostate cancer in smokers: meta-analysis of 2779 cases and 3484 controls. PLoS One 7: e30309. http://dx.doi.org/10.1371/journal.pone.0030309
32. Yaqinuddin A, Qureshi SA, Pervez S, Bashir MU, et al. (2013). Frequent DNA hypermethylation at the RASSF1A and APC gene loci in prostate cancer patients of Pakistani origin. ISRN Urol. 2013: 627249. http://dx.doi.org/10.1155/2013/627249
33. Yoon JH, Dammann R and Pfeifer GP (2001). Hypermethylation of the CpG island of the RASSF1A gene in ovarian and renal cell carcinomas. Int. J. Cancer 94: 212-217. http://dx.doi.org/10.1002/ijc.1466
34. Zhai X and Li SJ (2014). Methylation of RASSF1A and CDH13 genes in individualized chemotherapy for patients with non- small cell lung cancer. Asian Pac. J. Cancer Prev. 15: 4925-4928. http://dx.doi.org/10.7314/APJCP.2014.15.12.4925
35. Zhang Jian-Ying LZ (2008). Methylation of RASSF1A and BLU in bladder carcinoma and renal carcinoma. Zhe Jiang Clin. Med. 10: 1418-1420.