Clinical utility of patient-derived xenografts to determine biomarkers of prognosis and map resistance pathways in EGFR-mutant lung adenocarcinoma
Stewart EL, Mascaux C, Pham N-A, et al: Clinical utility of patient-derived xenografts to determine biomarkers of prognosis and map resistance pathways in EGFR-mutant lung adenocarcinoma. J Clin Oncol 33:2472-2480, 2015
Bridging tumor genomics to patient outcomes through an integrated patient-derived xenograft platform
Gandara DR, Mack PC, Bult C, et al: Bridging tumor genomics to patient outcomes through an integrated patient-derived xenograft platform. Clin Lung Cancer 16:165-172, 2015
Tumor grafts derived from women with breast cancer authentically reflect tumor pathology, growth, metastasis and disease outcomes
DeRose YS, Wang G, Lin YC, et al: Tumor grafts derived from women with breast cancer authentically reflect tumor pathology, growth, metastasis and disease outcomes. Nat Med 17:1514-1520, 2011
The ability to form primary tumor xenografts is predictive of increased risk of disease recurrence in early-stage non-small cell lung cancer
John T, Kohler D, Pintilie M, Yanagawa N, et al: The ability to form primary tumor xenografts is predictive of increased risk of disease recurrence in early-stage non-small cell lung cancer. Clin Cancer Res 17:134-141, 2011
Long-term engraftment and expansion of tumor-derived memory T cells following the implantation of non-disrupted pieces of human lung tumor into NOD-scid IL2Rgamma(null) mice
Simpson-Abelson MR, Sonnenberg GF, Takita H, et al: Long-term engraftment and expansion of tumor-derived memory T cells following the implantation of non-disrupted pieces of human lung tumor into NOD-scid IL2Rgamma(null) mice. J Immunol 180:7009-7018, 2008
A pilot clinical study of treatment guided by personalized tumor grafts in patients with advanced cancer
Hidalgo M, Bruckheimer E, Rajeshkumar NV, et al: A pilot clinical study of treatment guided by personalized tumor grafts in patients with advanced cancer. Mol Cancer Ther 10:1311-1316, 2011
Patient-derived xenograft models: An emerging platform for translational cancer research
Hidalgo M, Amant F, Biankin AV, et al: Patient-derived xenograft models: An emerging platform for translational cancer research. Cancer Discov 4:998-1013, 2014
Immunodeficient mouse model for human hematopoietic stem cell engraftment and immune system development
Aryee KE, Schultz LD, Brehm MA: Immunodeficient mouse model for human hematopoietic stem cell engraftment and immune system development. Methods Mol Biol 1185:267-278, 2014