Integrated processes for expansion and differentiation of human pluripotent stem cells in suspended microcarriers cultures

Biochemical and Biophysical Research Communications

Volumn 473, Issue 3, 2016, Pages 764-768

  Lam, Alan Tin Lun ^a   Chen, Allen Kuan Liang ^a   Ting, Sherwin Qi Peng ^a   Reuveny, Shaul ^a   Oh, Steve Kah Weng ^a  

^a AGENCY FOR SCIENCE   (Singapore)

Author keywords

Extracellular matrix proteins; Human embryonic stem cells; Human induced pluripotent stem cells; Human pluripotent stem cells; Integration of expansion and differentiation; Microcarriers

Indexed keywords

SCLEROPROTEIN;

CARDIAC MUSCLE CELL; CELL AGGREGATION; CELL CULTURE TECHNIQUE; CELL DIFFERENTIATION; CELL EXPANSION; CELL SIZE; HUMAN; NEURAL STEM CELL; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; REVIEW; BIOLOGICAL THERAPY; CELL CULTURE; CELL PROLIFERATION; CYTOLOGY; EMBRYONIC STEM CELL; METABOLISM; NERVE CELL; PROCEDURES; STEM CELL;

CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL- AND TISSUE-BASED THERAPY; CELLS, CULTURED; EMBRYONIC STEM CELLS; HUMANS; MYOCYTES, CARDIAC; NEURONS; PLURIPOTENT STEM CELLS; STEM CELLS;

EID: 84964684029     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2015.09.079     Document Type: Review

References (42)

1. G. Keller Embryonic stem cell differentiation: emergence of a new era in biology and medicine Genes Dev. 19 2005 1129 1155
2. S. Sart, Y.J. Schneider, Y. Li, and S.N. Agathos Stem cell bioprocess engineering towards cGMP production and clinical applications Cytotechnology 66 2014 709 722
3. A.K. Chen, S. Reuveny, and S.K. Oh Application of human mesenchymal and pluripotent stem cell microcarrier cultures in cellular therapy: achievements and future direction Biotechnol. Adv. 31 2013 1032 1046
4. J. Rowley, E. Abraham, A. Campbell, H. Brandwein, and S. Oh Meeting lot-size challenges of manufacturing adherent cells for therapy Bioprocess Int. 10 2012 16 22
5. A.K. Chen, X. Chen, A.B. Choo, S. Reuveny, and S.K. Oh Expansion of human embryonic stem cells on cellulose microcarriers Curr. Protoc. Stem Cell Biol. 1 2010 Unit 1C 11
6. A.K. Chen, X. Chen, A.B. Choo, S. Reuveny, and S.K. Oh Critical microcarrier properties affecting the expansion of undifferentiated human embryonic stem cells Stem Cell Res. 7 2011 97 111
7. A.T. Lam, J. Li, A.K. Chen, W.R. Birch, S. Reuveny, and S.K. Oh Improved human pluripotent stem cell attachment and spreading on xeno-free laminin-521-coated microcarriers results in efficient growth in agitated cultures Biores. Open Access 4 2015 242 257
8. A.T. Lam, J. Li, A.K. Chen, S. Reuveny, S.K. Oh, and W.R. Birch Cationic surface charge combined with either vitronectin or laminin dictates the evolution of human embryonic stem cells/microcarrier aggregates and cell growth in agitated cultures Stem Cells Dev. 23 2014 1688 1703
9. S.K. Oh, A.K. Chen, Y. Mok, X. Chen, U.M. Lim, A. Chin, A.B. Choo, and S. Reuveny Long-term microcarrier suspension cultures of human embryonic stem cells Stem Cell Res. 2 2009 219 230
10. A.M. Fernandes, P.A. Marinho, R.C. Sartore, B.S. Paulsen, R.M. Mariante, L.R. Castilho, and S.K. Rehen Successful scale-up of human embryonic stem cell production in a stirred microcarrier culture system Braz. J. Med. Biol. Res. 42 2009 515 522
11. D.E. Kehoe, D. Jing, L.T. Lock, and E.S. Tzanakakis Scalable stirred-suspension bioreactor culture of human pluripotent stem cells Tissue Eng. Part A 16 2010 405 421
12. Y. Nie, V. Bergendahl, D.J. Hei, J.M. Jones, and S.P. Palecek Scalable culture and cryopreservation of human embryonic stem cells on microcarriers Biotechnol. Prog. 25 2009 20 31
13. B.C. Heng, J. Li, A.K. Chen, S. Reuveny, S.M. Cool, W.R. Birch, and S.K. Oh Translating human embryonic stem cells from 2-dimensional to 3-dimensional cultures in a defined medium on laminin- and vitronectin-coated surfaces Stem Cells Dev. 21 2012 1701 1715
14. A. Chen, S. Reuveny, and S.K. Oh Application of human mesenchymal and pluripotent stem cell microcarrier cultures in cellular therapy: achievements and future direction Biotechnol. Adv. 31 2013 1032 1046
15. H. Kurosawa Methods for inducing embryoid body formation: in vitro differentiation system of embryonic stem cells J. Biosci. Bioeng. 103 2007 389 398
16. L.T. Lock, and E.S. Tzanakakis Expansion and differentiation of human embryonic stem cells to endoderm progeny in a microcarrier stirred-suspension culture Tissue Eng. Part A 15 2009 2051 2063
17. A. Chen, S. Ting, J. Seow, S. Reuveny, and S. Oh Considerations in designing systems for large scale production of human cardiomyocytes from pluripotent stem cells Stem Cell Res. Ther. 5 2014 12
18. A.T. Lam, A.K. Chen, J. Li, W.R. Birch, S. Reuveny, and S.K. Oh Conjoint propagation and differentiation of human embryonic stem cells to cardiomyocytes in a defined microcarrier spinner culture Stem Cell Res. Ther. 5 2014 110
19. S. Ting, A. Chen, S. Reuveny, and S. Oh An intermittent rocking platform for integrated expansion and differentiation of human pluripotent stem cells to cardiomyocytes in suspended microcarrier cultures Stem Cell Res. 13 2014 202 213
20. M. Lecina, S. Ting, A. Choo, S. Reuveny, and S. Oh Scalable platform for human embryonic stem cell differentiation to cardiomyocytes in suspended microcarrier cultures Tissue Eng. Part C Methods 16 2010 1609 1619
21. J. Bardy, A.K. Chen, Y.M. Lim, S. Wu, S. Wei, H. Weiping, K. Chan, S. Reuveny, and S.K. Oh Microcarrier suspension cultures for high-density expansion and differentiation of human pluripotent stem cells to neural progenitor cells Tissue Eng. Part C Methods 19 2013 166 180
22. Y. Park, Y. Chen, L. Ordovas, and C.M. Verfaillie Hepatic differentiation of human embryonic stem cells on microcarriers J. Biotechnol. 174 2014 39 48
23. S.J. Lu, T. Kelley, Q. Feng, A. Chen, S. Reuveny, R. Lanza, and S.K. Oh 3D microcarrier system for efficient differentiation of human pluripotent stem cells into hematopoietic cells without feeders and serum [corrected] Regen. Med. 8 2013 413 424
24. S. Ting, M. Lecina, S. Reuveny, and S. Oh Differentiation of human embryonic stem cells to cardiomyocytes on microcarrier cultures Curr. Protoc. Stem Cell Biol. 1 2012 Unit1D 7
25. M. Serra, C. Brito, M.F. Sousa, J. Jensen, R. Tostoes, J. Clemente, R. Strehl, J. Hyllner, M.J. Carrondo, and P.M. Alves Improving expansion of pluripotent human embryonic stem cells in perfused bioreactors through oxygen control J. Biotechnol. 148 2010 208 215
26. F. Gattazzo, A. Urciuolo, and P. Bonaldo Extracellular matrix: a dynamic microenvironment for stem cell niche Biochim. Biophys. Acta 1840 2014 2506 2519
27. H. Taylor-Weiner, J.E. Schwarzbauer, and A.J. Engler Defined extracellular matrix components are necessary for definitive endoderm induction Stem Cells 31 2013 2084 2094
28. S. Sa, L. Wong, and K.E. McCloskey Combinatorial fibronectin and laminin signaling promote highly efficient cardiac differentiation of human embryonic stem cells Biores. Open Access 3 2014 150 161
29. T. Ezashi, P. Das, and R.M. Roberts Low O2 tensions and the prevention of differentiation of hES cells Proc. Natl. Acad. Sci. U. S. A. 102 2005 4783 4788
30. N.R. Forsyth, A. Musio, P. Vezzoni, A.H. Simpson, B.S. Noble, and J. McWhir Physiologic oxygen enhances human embryonic stem cell clonal recovery and reduces chromosomal abnormalities Cloning Stem Cells 8 2006 16 23
31. R. Peerani, B.M. Rao, C. Bauwens, T. Yin, G.A. Wood, A. Nagy, E. Kumacheva, and P.W. Zandstra Niche-mediated control of human embryonic stem cell self-renewal and differentiation EMBO J. 26 2007 4744 4755
32. J. Hua, L.E. Erickson, T.Y. Yiin, and L.A. Glasgow A review of the effects of shear and interfacial phenomena on cell viability Crit. Rev. Biotechnol. 13 1993 305 328
33. G. Kretzmer Influence of stress on adherent cells Adv. Biochem. Eng. Biotechnol. 67 2000 123 137
34. A.W. Nienow Reactor engineering in large scale animal cell culture Cytotechnology 50 2006 9 33
35. H.W. Leung, A. Chen, A.B. Choo, S. Reuveny, and S.K. Oh Agitation can induce differentiation of human pluripotent stem cells in microcarrier cultures Tissue Eng. Part C Methods 17 2011 165 172
36. D. Steiner, H. Khaner, M. Cohen, S. Even-Ram, Y. Gil, P. Itsykson, T. Turetsky, M. Idelson, E. Aizenman, R. Ram, Y. Berman-Zaken, and B. Reubinoff Derivation, propagation and controlled differentiation of human embryonic stem cells in suspension Nat. Biotechnol. 28 2010 361 364
37. D. Jing, A. Parikh, J.M. Canty Jr., and E.S. Tzanakakis Stem cells for heart cell therapies Tissue Eng. Part B Rev. 14 2008 393 406
38. M.A. Laflamme, and C.E. Murry Regenerating the heart Nat. Biotechnol. 23 2005 845 856
39. U. Sarig, E.B. Nguyen, Y. Wang, S. Ting, T. Bronshtein, H. Sarig, N. Dahan, M. Gvirtz, S. Reuveny, S.K. Oh, T. Scheper, Y.C. Boey, S.S. Venkatraman, and M. Machluf Pushing the envelope in tissue engineering: ex vivo production of thick vascularized cardiac extracellular matrix constructs Tissue Eng. Part A 21 2015 1507 1519
40. P.L. Martinez-Morales, A. Revilla, I. Ocana, C. Gonzalez, P. Sainz, D. McGuire, and I. Liste Progress in stem cell therapy for major human neurological disorders Stem Cell Rev. 9 2013 685 699
41. S.C. Zhang, M. Wernig, I.D. Duncan, O. Brustle, and J.A. Thomson In vitro differentiation of transplantable neural precursors from human embryonic stem cells Nat. Biotechnol. 19 2001 1129 1133
42. P. Koch, T. Opitz, J.A. Steinbeck, J. Ladewig, and O. Brustle A rosette-type, self-renewing human ES cell-derived neural stem cell with potential for in vitro instruction and synaptic integration, Proc. Natl. Acad. Sci. U. S. A. 106 2009 3225 3230