Expanded polyglutamine embedded in the endoplasmic reticulum causes membrane distortion and coincides with Bax insertion

Biochemical and Biophysical Research Communications

Volumn 474, Issue 2, 2016, Pages 259-263

  Ueda, Masashi ^a   Li, Shimo ^a   Itoh, Masanori ^a   Wang, Miao Xing ^a   Hayakawa, Miki ^a   Islam, Saiful ^a   Tana, ^a   Nakagawa, Kiyomi ^a   Chen, Huayue ^a,b   Nakagawa, Toshiyuki ^a  

^a GIFU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH   (Japan)

Author keywords

Apoptosis; Endoplasmic reticulum; Membrane; Polyglutamine

Indexed keywords

CASPASE 3; CASPASE 7; DIGITONIN; DOXYCYCLINE; POLYGLUTAMINE; PROTEIN BAX; PROTEINASE K; TRYPSIN; BAX PROTEIN, MOUSE; PEPTIDE;

APOPTOSIS; ARTICLE; ASSAY; CARBOXY TERMINAL SEQUENCE; CELL LYSATE; CELL NUCLEUS MEMBRANE; CELL STRUCTURE; CYTOSOL; ELECTRON MICROSCOPY; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM MEMBRANE; FLUORESCENCE PROTEASE PROTECTION ASSAY; HUMAN; HUMAN CELL; MICROSOME; MITOCHONDRION; PRIORITY JOURNAL; PROTEIN DEGRADATION; CELL MEMBRANE; HEK293 CELL LINE; MEMBRANE FLUIDITY; METABOLISM; PHYSIOLOGY; ULTRASTRUCTURE;

BCL-2-ASSOCIATED X PROTEIN; CELL MEMBRANE; ENDOPLASMIC RETICULUM; HEK293 CELLS; HUMANS; MEMBRANE FLUIDITY; PEPTIDES;

EID: 84964588021     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2016.04.034     Document Type: Article

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