A high-throughput method for direct detection of therapeutic oligonucleotide-induced gene silencing in vivo

Nucleic Acid Therapeutics

Volumn 26, Issue 2, 2016, Pages 86-92

  Coles, Andrew H ^a   Osborn, Maire F ^a   Alterman, Julia F ^a   Turanov, Anton A ^a   Godinho, Bruno M D C ^a   Kennington, Lori ^a   Chase, Kathryn ^a   Aronin, Neil ^a   Khvorova, Anastasia ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HUNTINGTIN; MESSENGER RNA; SMALL INTERFERING RNA;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORPUS STRIATUM; DNA DETERMINATION; DRUG EFFICACY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; GENE SILENCING; IN VIVO STUDY; LUMINESCENCE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PUNCH BIOPSY; REAL TIME POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SHEEP; ANIMAL; GENETICS; HIGH THROUGHPUT SCREENING; METABOLISM; REPRODUCIBILITY;

ANIMALS; GENE EXPRESSION; GENE KNOCKDOWN TECHNIQUES; GENE SILENCING; HIGH-THROUGHPUT SCREENING ASSAYS; MICE; REPRODUCIBILITY OF RESULTS; RNA, MESSENGER; RNA, SMALL INTERFERING;

EID: 84964556021     PISSN: 21593337     EISSN: 21593345     Source Type: Journal    
DOI: 10.1089/nat.2015.0578     Document Type: Article

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