Meltdose Tacrolimus Pharmacokinetics

Transplantation Proceedings

Volumn 48, Issue 2, 2016, Pages 420-423

  Baraldo, M ^a  

^a UNIVERSITY OF UDINE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

TACROLIMUS; DELAYED RELEASE FORMULATION; IMMUNOSUPPRESSIVE AGENT;

ARTICLE; CONCENTRATION AT STEADY-STATE; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG EFFICACY; DRUG HALF LIFE; DRUG METABOLISM; DRUG MONITORING; DRUG SAFETY; GRAFT RECIPIENT; HUMAN; PRACTICE GUIDELINE; PRIORITY JOURNAL; VOLUME OF DISTRIBUTION AT STEADY-STATE; BIOAVAILABILITY; DELAYED RELEASE FORMULATION; DRUG ADMINISTRATION; GRAFT REJECTION; KIDNEY TRANSPLANTATION; LIVER TRANSPLANTATION; TIME FACTOR;

BIOLOGICAL AVAILABILITY; DELAYED-ACTION PREPARATIONS; DRUG ADMINISTRATION SCHEDULE; DRUG MONITORING; GRAFT REJECTION; HUMANS; IMMUNOSUPPRESSIVE AGENTS; KIDNEY TRANSPLANTATION; LIVER TRANSPLANTATION; TACROLIMUS; TIME FACTORS;

EID: 84964483943     PISSN: 00411345     EISSN: 18732623     Source Type: Journal    
DOI: 10.1016/j.transproceed.2016.02.002     Document Type: Article

References (16)

1. R. Baker, A. Jardine, and P. Andrews Renal Association Clinical Practice Guideline on post-operative care of the kidney transplant recipient Nephron Clin Pract 118 Suppl 1 2011 c311 c347
2. Y. Hashimoto, H. Sasa, M. Shimomura, and et al. Effects of intestinal and hepatic metabolism on the bioavailability of tacrolimus in rats Pharm Res 15 1998 1609 1613
3. M. Antignac, B. Barrou, R. Farinotti, and et al. Population pharmacokinetics and bioavailability of tacrolimus in kidney transplant patients Br J Clin Pharmacol 64 2007 750 757
4. C.E. Staatz, and S.E. Tett Clinical pharmacokinetics and pharmacodynamics of tacrolimus in solid organ transplantation Clin Pharmacokinet 43 2004 623 653
5. M. Rovelli, D. Palmeri, E. Vossler, and et al. Noncompliance in organ transplant recipients Transplant Proc 21 1989 833 834
6. J.A. Butler, P. Roderick, M. Mullee, and et al. Frequency and impact of non-adherence to immunosuppressants after renal transplantation: a systematic review Transplantation 77 2004 769 789
7. F.L. Weng, A.K. Israni, M.M. Joffe, and et al. Race and electronically measured adherence to immunosuppressive medications after deceased donor renal transplantation J Am Soc Nephrol 16 2005 1839 1848
8. K. Pathak, and S. Raghuvanshi Oral bioavailability: issues and solutions via nanoformulations Clin Pharmacokinet 54 2015 325 357
9. P. Buch, P. Holm, J.Q. Thomassen, and et al. IVIVC for fenofibrate immediate release tablets using solubility and permeability as in vitro predictors for pharmacokinetics J Pharm Sci 99 2010 4427 4436
10. K.P. Garnok-Jones Tacrolimus prolonged release (Envarsus®): a review of its use in kidney and liver transplant recipients Drugs 75 2015 309 320
11. Nigro V, Glicklich A, Weinberg J. Improved bioavailability of MELTDOSE once-daily formulation of tacrolimus (LCP-Tacro) with controlled agglomeration allows for consistent absorption over 24 hrs: a scintigraphic and pharmacokinetic evaluation. Edison, NJ: Veloxis Pharmaceuticals. Abstract number: B1034.
12. A.O. Gaber, R.R. Alloway, K. Bodziak, and et al. Conversion from twice-daily tacrolimus capsules to once-daily extended-release tacrolimus (LCPT): a phase 2 trial of stable renal transplant recipients Transplantation 96 2013 191 197
13. R.R. Alloway, D.E. Eckhoff, W.K. Washburn, and et al. Teperman4 conversion from twice daily tacrolimus capsules to once daily extended-release tacrolimus (LCP-Tacro): phase 2 trial of stable liver transplant recipients Liver Transpl 20 2014 564 575
14. J.M. Grinyo, and S. Petruzzelli Once-daily LCP-Tacro MeltDose tacrolimus for the prophylaxis of organ rejection in kidney and liver transplantations Expert Rev Clin Immunol 10 2014 1567 1579
15. S. Bunnapradist, K. Ciechanowski, P. West-Thielke, and et al. Conversion from twice-daily tacrolimus to once-daily extended release tacrolimus (LCPT): the phase III randomized MELT trial Am J Transplant 13 2013 760 769
16. European Medicines Agency Envarsus (tacrolimus extended release tablets): EU summary of product characteristics 2014 Available at: www.ema.europa.eu/ Accessed September 17, 2014