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Volumn 6, Issue 1, 2016, Pages 20-28

Hyperkalemia constitutes a constraint for implementing renin-angiotensin-aldosterone inhibition: The widening gap between mandated treatment guidelines and the real-world clinical arena

Author keywords

big data analytics; cardiorenal comorbidities; chronic kidney disease; guideline recommendations for RAASi treatment; hyperkalemia; MR antagonism; prescribing patterns for RAASi; renin angiotensin inhibition

Indexed keywords


EID: 84964413642     PISSN: 21571724     EISSN: 21571716     Source Type: Journal    
DOI: 10.1016/j.kisu.2016.01.004     Document Type: Review
Times cited : (50)

References (56)
  • 1
    • 84964414231 scopus 로고    scopus 로고
    • Epidemiology of hyperkalemia: An update
    • C.P. Kovesdy Epidemiology of hyperkalemia: an update Kidney Int Suppl 6 2016 3 6
    • (2016) Kidney Int Suppl , vol.6 , pp. 3-6
    • Kovesdy, C.P.1
  • 2
    • 84964459249 scopus 로고    scopus 로고
    • Electrophysiological and clinical consequences of hyperkalemia
    • V.M. Campese, and G. Adenuga Electrophysiological and clinical consequences of hyperkalemia Kidney Int Suppl 6 2016 16 19
    • (2016) Kidney Int Suppl , vol.6 , pp. 16-19
    • Campese, V.M.1    Adenuga, G.2
  • 3
    • 33745162185 scopus 로고    scopus 로고
    • Role of the renin-angiotensin-aldosterone system and proinflammatory mediators in cardiovascular disease
    • C.M. Ferrario, and W.B. Strawn Role of the renin-angiotensin-aldosterone system and proinflammatory mediators in cardiovascular disease Am J Cardiol 98 2006 121 128
    • (2006) Am J Cardiol , vol.98 , pp. 121-128
    • Ferrario, C.M.1    Strawn, W.B.2
  • 4
    • 84884500364 scopus 로고    scopus 로고
    • Renin-angiotensin-aldosterone system inhibitors in heart failure
    • F. Shearer, C.C. Lang, and A.D. Struthers Renin-angiotensin-aldosterone system inhibitors in heart failure Clin Pharmacol Ther 94 2013 459 467
    • (2013) Clin Pharmacol Ther , vol.94 , pp. 459-467
    • Shearer, F.1    Lang, C.C.2    Struthers, A.D.3
  • 5
    • 84897696565 scopus 로고    scopus 로고
    • Renoprotective effect of renin-angiotensin-aldosterone system blockade in patients with predialysis advanced chronic kidney disease, hypertension, and anemia
    • T.W. Hsu, J.S. Liu, S.C. Hung, and et al. Renoprotective effect of renin-angiotensin-aldosterone system blockade in patients with predialysis advanced chronic kidney disease, hypertension, and anemia JAMA Intern Med 174 2014 347 354
    • (2014) JAMA Intern Med , vol.174 , pp. 347-354
    • Hsu, T.W.1    Liu, J.S.2    Hung, S.C.3
  • 6
    • 33845902544 scopus 로고    scopus 로고
    • The cardiovascular disease continuum validated: Clinical evidence of improved patient outcomes: Part I: Pathophysiology and clinical trial evidence (risk factors through stable coronary artery disease)
    • V.J. Dzau, E.M. Antman, H.R. Black, and et al. The cardiovascular disease continuum validated: clinical evidence of improved patient outcomes: part I: pathophysiology and clinical trial evidence (risk factors through stable coronary artery disease) Circulation 114 2006 2850 2870
    • (2006) Circulation , vol.114 , pp. 2850-2870
    • Dzau, V.J.1    Antman, E.M.2    Black, H.R.3
  • 7
    • 74949092226 scopus 로고    scopus 로고
    • New physiological concepts of the renin-angiotensin system from the investigation of precursors and products of angiotensin i metabolism
    • C.M. Ferrario New physiological concepts of the renin-angiotensin system from the investigation of precursors and products of angiotensin I metabolism Hypertension 55 2010 445 452
    • (2010) Hypertension , vol.55 , pp. 445-452
    • Ferrario, C.M.1
  • 8
    • 0009307914 scopus 로고    scopus 로고
    • 1 receptor blockade
    • M. Epstein, H.R. Brunner, Hanley & Belfus, Inc. Philadelphia, PA
    • 1 receptor blockade M. Epstein, H.R. Brunner, Angiotensin II Receptor Antagonists 2000 Hanley & Belfus, Inc. Philadelphia, PA 235 256
    • (2000) Angiotensin II Receptor Antagonists , pp. 235-256
    • Grant, S.L.1    Griendline, K.K.2
  • 9
    • 0009435825 scopus 로고    scopus 로고
    • 1 receptor blockade
    • M. Epstein, H.R. Brunner, Hanley & Belfus, Inc. Philadelphia, PA
    • 1 receptor blockade M. Epstein, H.R. Brunner, Angiotensin II Receptor Antagonists 2000 Hanley & Belfus, Inc. Philadelphia, PA 215 222
    • (2000) Angiotensin II Receptor Antagonists , pp. 215-222
    • Gavras, I.1    Gavras, H.2
  • 10
    • 0003077994 scopus 로고    scopus 로고
    • 1 receptor antagonists as antihypertensive agents
    • M. Epstein, H.R. Brunner, Hanley & Belfus, Inc. Philadelphia, PA
    • 1 receptor antagonists as antihypertensive agents M. Epstein, H.R. Brunner, Angiotensin II Receptor Antagonists 2000 Hanley & Belfus, Inc. Philadelphia, PA 263 278
    • (2000) Angiotensin II Receptor Antagonists , pp. 263-278
    • Fabiani, M.E.1    Johnston, C.I.2
  • 11
    • 0002570138 scopus 로고    scopus 로고
    • Wall stress, angiotensin II, and left ventricular hypertrophy
    • M. Epstein, H.R. Brunner, Hanley & Belfus, Inc. Philadelphia, PA
    • T.O. Morgan, C.D. Griffiths, and L.M.D. Delbridge Wall stress, angiotensin II, and left ventricular hypertrophy M. Epstein, H.R. Brunner, Angiotensin II Receptor Antagonists 2000 Hanley & Belfus, Inc. Philadelphia, PA 223 234
    • (2000) Angiotensin II Receptor Antagonists , pp. 223-234
    • Morgan, T.O.1    Griffiths, C.D.2    Delbridge, L.M.D.3
  • 12
    • 0345785961 scopus 로고    scopus 로고
    • 1 angiotensin receptors in vascular remodeling in hypertension
    • M. Epstein, H.R. Brunner, Hanley & Belfus; Inc. Philadelphia, PA
    • 1 angiotensin receptors in vascular remodeling in hypertension M. Epstein, H.R. Brunner, Angiotensin II Receptor Antagonists 2000 Hanley & Belfus; Inc. Philadelphia, PA 279 294
    • (2000) Angiotensin II Receptor Antagonists , pp. 279-294
    • Schiffrin, E.L.1    Hayoz, D.2
  • 14
    • 84864983805 scopus 로고    scopus 로고
    • Angiotensin II, aldosterone, and anti-inflammatory lymphocytes: Interplay and therapeutic opportunities
    • D.A. Kasal, and E.L. Schiffrin Angiotensin II, aldosterone, and anti-inflammatory lymphocytes: interplay and therapeutic opportunities Int J Hypertens 2012 2012 829786 http://dx.doi.org/10.1155/2012/829786
    • (2012) Int J Hypertens , vol.2012 , pp. 829786
    • Kasal, D.A.1    Schiffrin, E.L.2
  • 15
    • 84948823375 scopus 로고    scopus 로고
    • Renin-angiotensin system inhibitors and kidney and cardiovascular outcomes in patients with CKD: A Bayesian network meta-analysis of randomized clinical trials [e-pub ahead of print]
    • Accessed December 15, 2015
    • Xie X, Liu Y, Perkovic V, et al. Renin-angiotensin system inhibitors and kidney and cardiovascular outcomes in patients with CKD: a Bayesian network meta-analysis of randomized clinical trials [e-pub ahead of print]. Am J Kidney Dis. http://dx.doi.org/10.1053/j.ajkd.2015.10.011, accessed December 15, 2015.
    • Am J Kidney Dis.
    • Xie, X.1    Liu, Y.2    Perkovic, V.3
  • 16
    • 0023266532 scopus 로고
    • Effects of enalapril on mortality in severe congestive heart failure: Results of the Cooperative North Scandinavian Enalapril Survival Study (CONSENSUS)
    • The CONSENSUS Trial Study Group Effects of enalapril on mortality in severe congestive heart failure: results of the Cooperative North Scandinavian Enalapril Survival Study (CONSENSUS) N Engl J Med 316 1987 1429 1435
    • (1987) N Engl J Med , vol.316 , pp. 1429-1435
  • 17
    • 0034088314 scopus 로고    scopus 로고
    • Clinical pharmacokinetics of angiotensin II (AT1) receptor blockers in hypertension
    • Z.H. Israili Clinical pharmacokinetics of angiotensin II (AT1) receptor blockers in hypertension J Hum Hypertens 14 suppl 1 2000 S73 S86
    • (2000) J Hum Hypertens , vol.14 , pp. S73-S86
    • Israili, Z.H.1
  • 18
    • 84884294190 scopus 로고    scopus 로고
    • 2013 ACCF/AHA guideline for the management of heart failure: A report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines
    • C.W. Yancy, M. Jessup, B. Bozkurt, and et al. 2013 ACCF/AHA guideline for the management of heart failure: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines J Am Coll Cardiol 62 2013 e147 e239
    • (2013) J Am Coll Cardiol , vol.62 , pp. e147-e239
    • Yancy, C.W.1    Jessup, M.2    Bozkurt, B.3
  • 19
    • 84864493727 scopus 로고    scopus 로고
    • ESC guidelines for the diagnosis and treatment of acute and chronic heart failure 2012: The Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2012 of the European Society of Cardiology: Developed in collaboration with the Heart Failure Association (HFA) of the ESC
    • J.J. McMurray, S. Adamopoulos, S.D. Anker, and et al. ESC guidelines for the diagnosis and treatment of acute and chronic heart failure 2012: the Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2012 of the European Society of Cardiology: developed in collaboration with the Heart Failure Association (HFA) of the ESC Eur Heart J 33 2012 1787 1847
    • (2012) Eur Heart J , vol.33 , pp. 1787-1847
    • McMurray, J.J.1    Adamopoulos, S.2    Anker, S.D.3
  • 20
    • 84884293874 scopus 로고    scopus 로고
    • KDIGO clinical practice guideline for the management of blood pressure in chronic kidney disease
    • Kidney Disease Improving Global Outcomes (KDIGO) Working Group KDIGO clinical practice guideline for the management of blood pressure in chronic kidney disease Kidney Int Suppl 2 2012 337 414
    • (2012) Kidney Int Suppl , vol.2 , pp. 337-414
  • 21
    • 84896705051 scopus 로고    scopus 로고
    • KDIGO 2012 clinical practice guideline for the evaluation and management of chronic kidney disease
    • Kidney Disease Improving Global Outcomes (KDIGO) CKD Work Group KDIGO 2012 clinical practice guideline for the evaluation and management of chronic kidney disease Kidney Int Suppl 3 2013 1 150
    • (2013) Kidney Int Suppl , vol.3 , pp. 1-150
  • 22
    • 84888016838 scopus 로고    scopus 로고
    • KDIGO clinical practice guideline for lipid management in chronic kidney disease
    • Kidney Disease Improving Global Outcomes (KDIGO) Lipid Work Group KDIGO clinical practice guideline for lipid management in chronic kidney disease Kidney Int Suppl 3 2013 259 305
    • (2013) Kidney Int Suppl , vol.3 , pp. 259-305
  • 23
    • 84898869053 scopus 로고    scopus 로고
    • KDOQI US Commentary on the 2012 KDIGO clinical practice guideline for the evaluation and management of CKD
    • L.A. Inker, B.C. Astor, C.H. Fox, and et al. KDOQI US Commentary on the 2012 KDIGO clinical practice guideline for the evaluation and management of CKD Am J Kidney Dis 63 2014 713 735
    • (2014) Am J Kidney Dis , vol.63 , pp. 713-735
    • Inker, L.A.1    Astor, B.C.2    Fox, C.H.3
  • 24
    • 84893549987 scopus 로고    scopus 로고
    • 2014 evidence-based guideline for the management of high blood pressure in adults: Report from the panel members appointed to the Eighth Joint National Committee (JNC 8)
    • P.A. James, S. Oparil, B.L. Carter, and et al. 2014 evidence-based guideline for the management of high blood pressure in adults: report from the panel members appointed to the Eighth Joint National Committee (JNC 8) JAMA 311 2014 507 520
    • (2014) JAMA , vol.311 , pp. 507-520
    • James, P.A.1    Oparil, S.2    Carter, B.L.3
  • 25
    • 84880644910 scopus 로고    scopus 로고
    • KDOQI US commentary on the 2012 KDIGO clinical practice guideline for management of blood pressure in CKD
    • S.J. Taler, R. Agarwal, G.L. Bakris, and et al. KDOQI US commentary on the 2012 KDIGO clinical practice guideline for management of blood pressure in CKD Am J Kidney Dis 62 2013 201 213
    • (2013) Am J Kidney Dis , vol.62 , pp. 201-213
    • Taler, S.J.1    Agarwal, R.2    Bakris, G.L.3
  • 26
    • 84958584867 scopus 로고    scopus 로고
    • Cardiovascular disease and risk management
    • American Diabetes Association Cardiovascular disease and risk management Diabetes Care 39 suppl 2016 S60 S71
    • (2016) Diabetes Care , vol.39 , pp. S60-S71
  • 27
    • 84962330516 scopus 로고    scopus 로고
    • American Diabetes Association. Microvascular complications and foot care
    • American Diabetes Association. Microvascular complications and foot care Diabetes Care 39 suppl 1 2016 S72 S80
    • (2016) Diabetes Care , vol.39 , pp. S72-S80
  • 28
    • 84880015206 scopus 로고    scopus 로고
    • 2013 ESH/ESC guidelines for the management of arterial hypertension: The Task Force for the management of arterial hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC)
    • G. Mancia, R. Fagard, K. Narkiewicz, and et al. 2013 ESH/ESC guidelines for the management of arterial hypertension: the Task Force for the management of arterial hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC) J Hypertens 31 2013 1281 1357
    • (2013) J Hypertens , vol.31 , pp. 1281-1357
    • Mancia, G.1    Fagard, R.2    Narkiewicz, K.3
  • 29
    • 24044466543 scopus 로고    scopus 로고
    • The adequacy of laboratory monitoring in patients treated with spironolactone for congestive heart failure
    • K.B. Shah, K. Rao, R. Sawyer, and S.S. Gottlieb The adequacy of laboratory monitoring in patients treated with spironolactone for congestive heart failure J Am Coll Cardiol 46 2005 845 849
    • (2005) J Am Coll Cardiol , vol.46 , pp. 845-849
    • Shah, K.B.1    Rao, K.2    Sawyer, R.3    Gottlieb, S.S.4
  • 30
    • 0037438820 scopus 로고    scopus 로고
    • Complications of inappropriate use of spironolactone in heart failure: When an old medicine spirals out of new guidelines
    • B. Bozkurt, M.D. Agoston, and A.A. Knowlton Complications of inappropriate use of spironolactone in heart failure: when an old medicine spirals out of new guidelines J Am Coll Cardiol 41 2003 211 214
    • (2003) J Am Coll Cardiol , vol.41 , pp. 211-214
    • Bozkurt, B.1    Agoston, M.D.2    Knowlton, A.A.3
  • 31
    • 0033517302 scopus 로고    scopus 로고
    • The effect of spironolactone on morbidity and mortality in patients with severe heart failure
    • B. Pitt, F. Zannad, W.J. Remme, et al. for the Randomized Aldactone Evaluation Study Investigators The effect of spironolactone on morbidity and mortality in patients with severe heart failure N Engl J Med 341 1999 709 717
    • (1999) N Engl J Med , vol.341 , pp. 709-717
    • Pitt, B.1    Zannad, F.2    Remme, W.J.3
  • 32
    • 78650399880 scopus 로고    scopus 로고
    • Eplerenone in patients with systolic heart failure and mild symptoms
    • F. Zannad, J.J. McMurray, H. Krum, et al. for the EMPHASIS-HF Study Group Eplerenone in patients with systolic heart failure and mild symptoms N Engl J Med 364 2011 11 21
    • (2011) N Engl J Med , vol.364 , pp. 11-21
    • Zannad, F.1    McMurray, J.J.2    Krum, H.3
  • 33
    • 4644221457 scopus 로고    scopus 로고
    • Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization
    • A.S. Go, G.M. Chertow, D. Fan, and et al. Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization N Engl J Med 351 2004 1296 1305
    • (2004) N Engl J Med , vol.351 , pp. 1296-1305
    • Go, A.S.1    Chertow, G.M.2    Fan, D.3
  • 34
    • 84866385679 scopus 로고    scopus 로고
    • Major barriers against renin-angiotensin-aldosterone system blocker use in chronic kidney disease stages 3-5 in clinical practice: A safety concern?
    • T. Yildirim, M. Arici, S. Piskinpasa, and et al. Major barriers against renin-angiotensin-aldosterone system blocker use in chronic kidney disease stages 3-5 in clinical practice: a safety concern? Ren Fail 34 2012 1095 1099
    • (2012) Ren Fail , vol.34 , pp. 1095-1099
    • Yildirim, T.1    Arici, M.2    Piskinpasa, S.3
  • 35
    • 3442888821 scopus 로고    scopus 로고
    • Managing hyperkalemia caused by inhibitors of the renin-angiotensin-aldosterone system
    • B.F. Palmer Managing hyperkalemia caused by inhibitors of the renin-angiotensin-aldosterone system N Engl J Med 351 2004 585 592
    • (2004) N Engl J Med , vol.351 , pp. 585-592
    • Palmer, B.F.1
  • 36
    • 84903955528 scopus 로고    scopus 로고
    • Prediction and management of hyperkalemia across the spectrum of chronic kidney disease
    • I. Lazich, and G.L. Bakris Prediction and management of hyperkalemia across the spectrum of chronic kidney disease Semin Nephrol 34 2014 333 339
    • (2014) Semin Nephrol , vol.34 , pp. 333-339
    • Lazich, I.1    Bakris, G.L.2
  • 37
    • 84860617929 scopus 로고    scopus 로고
    • Hyperkalemia associated with use of angiotensin-converting enzyme inhibitors and angiotensin receptor blockers
    • M.A. Raebel Hyperkalemia associated with use of angiotensin-converting enzyme inhibitors and angiotensin receptor blockers Cardiovasc Ther 30 2012 e156 e166
    • (2012) Cardiovasc Ther , vol.30 , pp. e156-e166
    • Raebel, M.A.1
  • 38
    • 84864801182 scopus 로고    scopus 로고
    • Prevalence and factors associated with hyperkalemia in predialysis patients followed in a low-clearance clinic
    • P.A. Sarafidis, R. Blacklock, E. Wood, and et al. Prevalence and factors associated with hyperkalemia in predialysis patients followed in a low-clearance clinic Clin J Am Soc Nephrol 7 2012 1234 1241
    • (2012) Clin J Am Soc Nephrol , vol.7 , pp. 1234-1241
    • Sarafidis, P.A.1    Blacklock, R.2    Wood, E.3
  • 39
    • 84860493488 scopus 로고    scopus 로고
    • Predictors of hyperkalemia and death in patients with cardiac and renal disease
    • N. Jain, S. Kotla, B.B. Little, and et al. Predictors of hyperkalemia and death in patients with cardiac and renal disease Am J Cardiol 109 2012 1510 1513
    • (2012) Am J Cardiol , vol.109 , pp. 1510-1513
    • Jain, N.1    Kotla, S.2    Little, B.B.3
  • 40
    • 84908248239 scopus 로고    scopus 로고
    • Management of hyperkalaemia in chronic kidney disease
    • C.P. Kovesdy Management of hyperkalaemia in chronic kidney disease Nat Rev Nephrol 10 2014 653 662
    • (2014) Nat Rev Nephrol , vol.10 , pp. 653-662
    • Kovesdy, C.P.1
  • 41
    • 67649470527 scopus 로고    scopus 로고
    • The frequency of hyperkalemia and its significance in chronic kidney disease
    • L.M. Einhorn, M. Zhan, V.D. Hsu, and et al. The frequency of hyperkalemia and its significance in chronic kidney disease Arch Intern Med 169 2009 1156 1162
    • (2009) Arch Intern Med , vol.169 , pp. 1156-1162
    • Einhorn, L.M.1    Zhan, M.2    Hsu, V.D.3
  • 42
    • 0030799686 scopus 로고    scopus 로고
    • Hyperkalemia in the elderly: Drugs exacerbate impaired potassium homeostasis
    • M.A. Perazella, and R.L. Mahnensmith Hyperkalemia in the elderly: drugs exacerbate impaired potassium homeostasis J Gen Intern Med 12 1997 646 656
    • (1997) J Gen Intern Med , vol.12 , pp. 646-656
    • Perazella, M.A.1    Mahnensmith, R.L.2
  • 43
    • 77749292028 scopus 로고    scopus 로고
    • Potassium homeostasis and renin-angiotensin-aldosterone system inhibitors
    • M.R. Weir, and M. Rolfe Potassium homeostasis and renin-angiotensin-aldosterone system inhibitors Clin J Am Soc Nephrol 5 2010 531 548
    • (2010) Clin J Am Soc Nephrol , vol.5 , pp. 531-548
    • Weir, M.R.1    Rolfe, M.2
  • 44
    • 84937401175 scopus 로고    scopus 로고
    • Effect of patiromer on serum potassium level in patients with hyperkalemia and diabetic kidney disease: The AMETHYST-DN Randomized Clinical Trial
    • G.L. Bakris, B. Pitt, M.R. Weir, et al. The AMETHYST-DN Investigators Effect of patiromer on serum potassium level in patients with hyperkalemia and diabetic kidney disease: the AMETHYST-DN Randomized Clinical Trial JAMA 314 2015 151 161
    • (2015) JAMA , vol.314 , pp. 151-161
    • Bakris, G.L.1    Pitt, B.2    Weir, M.R.3
  • 45
    • 84907087561 scopus 로고    scopus 로고
    • Angiotensin-neprilysin inhibition versus enalapril in heart failure
    • J.J. McMurray, M. Packer, A.S. Desai, et al. for the PARADIGM-HF Investigators and Committees Angiotensin-neprilysin inhibition versus enalapril in heart failure N Engl J Med 371 2014 993 1004
    • (2014) N Engl J Med , vol.371 , pp. 993-1004
    • McMurray, J.J.1    Packer, M.2    Desai, A.S.3
  • 46
    • 79957930328 scopus 로고    scopus 로고
    • Patterns and predictors of evidence-based medication continuation among hospitalized heart failure patients (from Get with the Guidelines - Heart Failure)
    • M.J. Krantz, A.V. Ambardekar, L. Kaltenbach, et al. for the Get With the Guidelines Steering Committee and Hospitals Patterns and predictors of evidence-based medication continuation among hospitalized heart failure patients (from Get With the Guidelines - Heart Failure) Am J Cardiol 107 2011 1818 1823
    • (2011) Am J Cardiol , vol.107 , pp. 1818-1823
    • Krantz, M.J.1    Ambardekar, A.V.2    Kaltenbach, L.3
  • 47
    • 70350733579 scopus 로고    scopus 로고
    • Use of aldosterone antagonists in heart failure
    • N.M. Albert, C.W. Yancy, L. Liang, and et al. Use of aldosterone antagonists in heart failure JAMA 302 2009 1658 1665
    • (2009) JAMA , vol.302 , pp. 1658-1665
    • Albert, N.M.1    Yancy, C.W.2    Liang, L.3
  • 48
    • 84872022727 scopus 로고    scopus 로고
    • Temporal trends and predictors in the use of aldosterone antagonists post-acute myocardial infarction
    • A.N. Rassi, M.A. Cavender, G.C. Fonarow, and et al. Temporal trends and predictors in the use of aldosterone antagonists post-acute myocardial infarction J Am Coll Cardiol 61 2013 35 40
    • (2013) J Am Coll Cardiol , vol.61 , pp. 35-40
    • Rassi, A.N.1    Cavender, M.A.2    Fonarow, G.C.3
  • 49
    • 84885042198 scopus 로고    scopus 로고
    • Are hospitalized or ambulatory patients with heart failure treated in accordance with European Society of Cardiology guidelines? Evidence from 12,440 patients of the ESC Heart Failure Long-Term Registry
    • A.P. Maggioni, S.D. Anker, U. Dahlström, et al. for the Heart Failure Association of the ESC Are hospitalized or ambulatory patients with heart failure treated in accordance with European Society of Cardiology guidelines? Evidence from 12,440 patients of the ESC Heart Failure Long-Term Registry Eur J Heart Fail 15 2013 1173 1184
    • (2013) Eur J Heart Fail , vol.15 , pp. 1173-1184
    • Maggioni, A.P.1    Anker, S.D.2    Dahlström, U.3
  • 50
    • 84930437675 scopus 로고    scopus 로고
    • Underprescription of renin-angiotensin system blockers in moderate to severe chronic kidney disease
    • S. Shirazian, C.D. Grant, S. Mujeeb, and et al. Underprescription of renin-angiotensin system blockers in moderate to severe chronic kidney disease Am J Med Sci 349 2015 510 515
    • (2015) Am J Med Sci , vol.349 , pp. 510-515
    • Shirazian, S.1    Grant, C.D.2    Mujeeb, S.3
  • 51
    • 84941216266 scopus 로고    scopus 로고
    • Association between renin-angiotensin system antagonist use and mortality in heart failure with severe renal insufficiency: A prospective propensity score-matched cohort study
    • M. Edner, L. Benson, U. Dahlström, and L.H. Lund Association between renin-angiotensin system antagonist use and mortality in heart failure with severe renal insufficiency: a prospective propensity score-matched cohort study Eur Heart J 36 2015 2318 2326
    • (2015) Eur Heart J , vol.36 , pp. 2318-2326
    • Edner, M.1    Benson, L.2    Dahlström, U.3    Lund, L.H.4
  • 52
    • 85011968147 scopus 로고    scopus 로고
    • Evaluation of the treatment gap between clinical guidelines and the utilization of renin-angiotensin-aldosterone system inhibitors
    • M. Epstein, N.L. Reaven, S.E. Funk, and et al. Evaluation of the treatment gap between clinical guidelines and the utilization of renin-angiotensin-aldosterone system inhibitors Am J Manag Care 21 11 suppl 2015 S212 S220
    • (2015) Am J Manag Care , vol.21 , Issue.11 , pp. S212-S220
    • Epstein, M.1    Reaven, N.L.2    Funk, S.E.3
  • 53
    • 84964502092 scopus 로고    scopus 로고
    • Current and future treatment options for managing hyperkalemia
    • M.R. Weir Current and future treatment options for managing hyperkalemia Kidney Int Suppl 6 2016 29 34
    • (2016) Kidney Int Suppl , vol.6 , pp. 29-34
    • Weir, M.R.1
  • 54
    • 84920982556 scopus 로고    scopus 로고
    • Patiromer in patients with kidney disease and hyperkalemia receiving RAAS inhibitors
    • M.R. Weir, G.L. Bakris, D.A. Bushinsky, et al. OPAL-HK Investigators Patiromer in patients with kidney disease and hyperkalemia receiving RAAS inhibitors N Engl J Med 372 2015 211 221
    • (2015) N Engl J Med , vol.372 , pp. 211-221
    • Weir, M.R.1    Bakris, G.L.2    Bushinsky, D.A.3
  • 55
    • 84914703676 scopus 로고    scopus 로고
    • Effect of sodium zirconium cyclosilicate on potassium lowering for 28 days among outpatients with hyperkalemia: The HARMONIZE randomized clinical trial
    • M. Kosiborod, H.S. Rasmussen, P. Lavin, and et al. Effect of sodium zirconium cyclosilicate on potassium lowering for 28 days among outpatients with hyperkalemia: the HARMONIZE randomized clinical trial JAMA 312 2014 2223 2233
    • (2014) JAMA , vol.312 , pp. 2223-2233
    • Kosiborod, M.1    Rasmussen, H.S.2    Lavin, P.3
  • 56
    • 84920973726 scopus 로고    scopus 로고
    • Sodium zirconium cyclosilicate in hyperkalemia
    • D.K. Packham, H.S. Rasmussen, P.T. Lavin, and et al. Sodium zirconium cyclosilicate in hyperkalemia N Engl J Med 372 2015 222 231
    • (2015) N Engl J Med , vol.372 , pp. 222-231
    • Packham, D.K.1    Rasmussen, H.S.2    Lavin, P.T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.