Effect of Plasmodium inactivation in whole blood on the incidence of blood transfusion-transmitted malaria in endemic regions: The African Investigation of the Mirasol System (AIMS) randomised controlled trial

The Lancet

Volumn 387, Issue 10029, 2016, Pages 1753-1761

  Allain, Jean Pierre ^a   Owusu Ofori, Alex K ^b   Assennato, Sonny Michael ^a   Marschner, Susanne ^c   Goodrich, Raymond P ^c   Owusu Ofori, Shirley ^d  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b KWAME NKRUMAH UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Ghana)

^c Terumo BCT   (United States)

^d KOMFO ANOKYE TEACHING HOSPITAL   (Ghana)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; BIOCHEMICAL ANALYSIS; BLEEDING; BLOOD GROUP O; BLOOD TRANSFUSION; CONTROLLED STUDY; DISEASE TRANSMISSION; DOUBLE BLIND PROCEDURE; FEMALE; FEVER; HEMATOLOGICAL PARAMETERS; HUMAN; INCIDENCE; MAJOR CLINICAL STUDY; MALE; PARASITEMIA; PATHOGEN REDUCTION SYSTEM; PATIENT SAFETY; PLASMODIUM; PLASMODIUM MALARIAE INFECTION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; ADOLESCENT; ADVERSE EFFECTS; GHANA; MALARIA; MIDDLE AGED; TRANSMISSION; ULTRAVIOLET RADIATION; YOUNG ADULT;

PHOTOSENSITIZING AGENT; RIBOFLAVIN;

ADOLESCENT; ADULT; BLOOD TRANSFUSION; DOUBLE-BLIND METHOD; FEMALE; GHANA; HUMANS; INCIDENCE; MALARIA; MALE; MIDDLE AGED; PHOTOSENSITIZING AGENTS; PLASMODIUM; RIBOFLAVIN; ULTRAVIOLET RAYS; YOUNG ADULT;

EID: 84964413510     PISSN: 01406736     EISSN: 1474547X     Source Type: Journal    
DOI: 10.1016/S0140-6736(16)00581-X     Document Type: Article

References (15)

1. G Freimanis, M Sedagah, S Owusu-Ofori, S Kumar, JP Allain Investigating the prevalence of transfusion transmission of Plasmodium within a hyperendemic blood donation system Transfusion 53 2013 1429 1441
2. M ElChaar, S Atwal, GL Freimanis, B Dinko, CJ Sutherland, JP Allain Inactivation of Plasmodium falciparum in whole blood by riboflavin plus irradiation Transfusion 53 2013 3174 3183
3. S Owusu-Ofori, J Kusi, A Owusu-Ofori et al. Treatment of whole blood (WB) with riboflavin and UV light: impact on malaria parasite viability and WB storage Shock 44 suppl 1 2014 33 38
4. HF Pidcoke, SJ McFaul, AK Ramasubramanian et al. Primary hemostatic capacity of whole blood: A comprehensive analysis of pathogen reduction and refrigeration effects over time Transfusion 53 2013 137S 149S
5. OT Okoye, H Reddy, MD Wong et al. Large animal evaluation of riboflavin and ultraviolet light-treated whole blood transfused in a diffuse, nonsurgical bleeding porcine model Transfusion 55 2015 532 543
6. SK Volkman, PC Sabeti, D DeCaprio et al. A genome-wide map of diversity in Plasmodium falciparum Nat Genet 39 2007 113 119
7. M Kaesti, A Cortes, M Lagog, M Ott, HP Beck Longitudinal assessment of Plasmodium falciparum var gene transcription in naturally infected asymptomatic children in Papua New Guinea J Infect Dis 189 2004 1942 1951
8. D Eisen, H Billman-Jacobe, VF Marshall, D Fryauff, RL Coppel Temporal variation of the merozoite surface protein-2 gene of Plasmodium falciparum Infect Immun 66 1998 239 246
9. C Dechavanne, C Pierrat, E Renard et al. Genetic characterization of Plasmodium falciparum allelic variants infecting mothers at delivery and their children during their first plasmodial infections Infect Genome Evol 20 2013 16 25
10. A Ogouyemi-Hounto, D Kinde-Gazard, N Ndam et al. Genetic polymorphism or merozoite surface protein-1 and merozoite surface protein-2 in Plasmodium falciparum isolates from children in south of Benin Parasite 20 2013 37 43
11. S Owusu-Ofori, J Temple, F Sarkodie, D Candotti, JP Allain Predonation testing of potential blood donors in resource-restricted settings Transfusion 45 2005 1542 1543
12. D Candotti, F Sarkodie, JP Allain Residual risk of transfusion in Ghana Br J Haematol 113 2001 37 39
13. RP Goodrich, S Doane, HL Reddy Design and development of a method for the reduction of infectious pathogen load and inactivation of white blood cells in whole blood products Biologicals 38 2010 20 30
14. SD Keil, R Rapaport, SK Doane et al. Viral reduction of intracellular HIV using the Mirasol system for whole blood Vox Sang 103 suppl S1 2012 144
15. LD Fast, M Nevola, J Tavares et al. Treatment of whole blood with riboflavin plus ultraviolet light, an alternative to gamma irradiation in the prevention of transfusion associated graft-versus-host disease? Transfusion 53 2013 373 381