-
2
-
-
84908604358
-
International Myeloma Working Group updated criteria for the diagnosis of multiple myeloma
-
Rajkumar SV, Dimopoulos MA, Palumbo A, et al. International Myeloma Working Group updated criteria for the diagnosis of multiple myeloma. Lancet Oncol 2014;15:e538-548.
-
(2014)
Lancet Oncol
, vol.15
, pp. e538-e548
-
-
Rajkumar, S.V.1
Dimopoulos, M.A.2
Palumbo, A.3
-
3
-
-
20644460600
-
International staging system for multiple myeloma
-
Greipp PR, San Miguel J, Durie BG, et al. International staging system for multiple myeloma. J Clin Oncol 2005;23:3412-3420.
-
(2005)
J Clin Oncol
, vol.23
, pp. 3412-3420
-
-
Greipp, P.R.1
San Miguel, J.2
Durie, B.G.3
-
4
-
-
0016804136
-
A clinical staging system for multiple myeloma. Correlation of measured myeloma cell mass with presenting clinical features, response to treatment, and survival
-
Durie BG, Salmon SE. A clinical staging system for multiple myeloma. Correlation of measured myeloma cell mass with presenting clinical features, response to treatment, and survival. Cancer 1975;36:842-854.
-
(1975)
Cancer
, vol.36
, pp. 842-854
-
-
Durie, B.G.1
Salmon, S.E.2
-
5
-
-
84951020021
-
Revised international staging system for Multiple myeloma: A report from international Myeloma working group
-
Palumbo A, Avet-Loiseau H, Oliva S, et al. Revised International Staging System for multiple myeloma: a report from International Myeloma Working Group. J Clin Oncol 2015;33:2863-2869.
-
(2015)
J Clin Oncol
, vol.33
, pp. 2863-2869
-
-
Palumbo, A.1
Avet-Loiseau, H.2
Oliva, S.3
-
6
-
-
77954618168
-
Lenalidomide, bortezomib, and dexamethasone combination therapy in patients with newly diagnosed multiple myeloma
-
Richardson PG, Weller E, Lonial S, et al. Lenalidomide, bortezomib, and dexamethasone combination therapy in patients with newly diagnosed multiple myeloma. Blood 2010;116:679-686.
-
(2010)
Blood
, vol.116
, pp. 679-686
-
-
Richardson, P.G.1
Weller, E.2
Lonial, S.3
-
7
-
-
84906819363
-
Front-line transplantation program with lenalidomide, bortezomib, and dexamethasone combination as induction and consolidation followed by lenalidomide maintenance in patients with multiple myeloma: A phase II study by the Intergroupe Francophone du Myelome
-
Roussel M, Lauwers-Cances V, Robillard N, et al. Front-line transplantation program with lenalidomide, bortezomib, and dexamethasone combination as induction and consolidation followed by lenalidomide maintenance in patients with multiple myeloma: a phase II study by the Intergroupe Francophone du Myelome. J Clin Oncol 2014;32:2712-2717.
-
(2014)
J Clin Oncol
, vol.32
, pp. 2712-2717
-
-
Roussel, M.1
Lauwers-Cances, V.2
Robillard, N.3
-
8
-
-
84860907057
-
Randomized, multicenter, phase 2 study (EVOLUTION) of combinations of bortezomib, dexamethasone, cyclophosphamide, and lenalidomide in previously untreated multiple myeloma
-
Kumar S, Flinn I, Richardson PG, et al. Randomized, multicenter, phase 2 study (EVOLUTION) of combinations of bortezomib, dexamethasone, cyclophosphamide, and lenalidomide in previously untreated multiple myeloma. Blood 2012;119:4375-4382.
-
(2012)
Blood
, vol.119
, pp. 4375-4382
-
-
Kumar, S.1
Flinn, I.2
Richardson, P.G.3
-
9
-
-
84954253780
-
Bortezomib, lenalidomide and dexamethasone vs. Lenalidomide and dexamethasone in patients (pts) with previously untreated multiple myeloma without an intent for immediate autologous stem cell transplant (ASCT): Results of the randomized phase III trial SWOG S0777 [abstract]
-
Durie B, Hoering A, Rajkumar S V, et al. Bortezomib, lenalidomide and dexamethasone vs. lenalidomide and dexamethasone in patients (pts) with previously untreated multiple myeloma without an intent for immediate autologous stem cell transplant (ASCT): results of the randomized phase III trial SWOG S0777 [abstract]. Blood 2015;126:25.
-
(2015)
Blood
, vol.126
, pp. 25
-
-
Durie, B.1
Hoering, A.2
Rajkumar, S.V.3
-
10
-
-
67650882695
-
Cyclophosphamide, bortezomib and dexamethasone induction for newly diagnosed multiple myeloma: High response rates in a phase II clinical trial
-
Reeder CB, Reece DE, Kukreti V, et al. Cyclophosphamide, bortezomib and dexamethasone induction for newly diagnosed multiple myeloma: high response rates in a phase II clinical trial. Leukemia 2009;23:1337-1341.
-
(2009)
Leukemia
, vol.23
, pp. 1337-1341
-
-
Reeder, C.B.1
Reece, D.E.2
Kukreti, V.3
-
11
-
-
77955452192
-
Velcade, intravenous cyclophosphamide and dexamethasone (VCD) induction for previously untreated multiple myeloma (German DSMM XIa Trial) [abstract]
-
131
-
Einsele H, Liebisch P, Langer C, et al. Velcade, intravenous cyclophosphamide and dexamethasone (VCD) induction for previously untreated multiple myeloma (German DSMM XIa Trial) [abstract]. Blood 2009;114: Abstract 131.
-
(2009)
Blood
, vol.114
-
-
Einsele, H.1
Liebisch, P.2
Langer, C.3
-
12
-
-
84916205635
-
Long-term survival with cyclophosphamide, bortezomib and dexamethasone induction therapy in patients with newly diagnosed multiple myeloma
-
Reeder CB, Reece DE, Kukreti V, et al. Long-term survival with cyclophosphamide, bortezomib and dexamethasone induction therapy in patients with newly diagnosed multiple myeloma. Br J Haematol 2014;167:563-565.
-
(2014)
Br J Haematol
, vol.167
, pp. 563-565
-
-
Reeder, C.B.1
Reece, D.E.2
Kukreti, V.3
-
13
-
-
77951453409
-
Once-versus twice-weekly bortezomib induction therapy with CyBorD in newly diagnosed multiple myeloma
-
Reeder CB, Reece DE, Kukreti V, et al. Once-versus twice-weekly bortezomib induction therapy with CyBorD in newly diagnosed multiple myeloma. Blood 2010;115:3416-3417.
-
(2010)
Blood
, vol.115
, pp. 3416-3417
-
-
Reeder, C.B.1
Reece, D.E.2
Kukreti, V.3
-
14
-
-
84964403545
-
Cyclophosphamide, bortezomib and dexamethasone (CyBORD) is a feasible and active regimen for non-transplant eligible multiple myeloma patients [abstract]
-
Jimenez-Zepeda VH, Duggan P, Neri PE, Bahlis NJ. Cyclophosphamide, bortezomib and dexamethasone (CyBORD) is a feasible and active regimen for non-transplant eligible multiple myeloma patients [abstract]. Blood 2014;124; 5751.
-
(2014)
Blood
, vol.124
, pp. 5751
-
-
Jimenez-Zepeda, V.H.1
Duggan, P.2
Neri, P.E.3
Bahlis, N.J.4
-
15
-
-
84925230724
-
Safety and tolerability of ixazomib, an oral proteasome inhibitor, in combination with lenalidomide and dexamethasone in patients with previously untreated multiple myeloma: An open-label phase 1/2 study
-
Kumar SK, Berdeja JG, Niesvizky R, et al. Safety and tolerability of ixazomib, an oral proteasome inhibitor, in combination with lenalidomide and dexamethasone in patients with previously untreated multiple myeloma: an open-label phase 1/2 study. Lancet Oncol 2014;15:1503-1512.
-
(2014)
Lancet Oncol
, vol.15
, pp. 1503-1512
-
-
Kumar, S.K.1
Berdeja, J.G.2
Niesvizky, R.3
-
16
-
-
84865333050
-
A phase 1/2 study of carfilzomib in combination with lenalidomide and low-dose dexamethasone as a frontline treatment for multiple myeloma
-
Jakubowiak AJ, Dytfeld D, Griffith KA, et al. A phase 1/2 study of carfilzomib in combination with lenalidomide and low-dose dexamethasone as a frontline treatment for multiple myeloma. Blood 2012;120:1801-1809.
-
(2012)
Blood
, vol.120
, pp. 1801-1809
-
-
Jakubowiak, A.J.1
Dytfeld, D.2
Griffith, K.A.3
-
17
-
-
84907309743
-
Carfilzomib, lenalidomide, and low-dose dexamethasone in elderly patients with newly diagnosed multiple myeloma
-
Dytfeld D, Jasielec J, Griffith KA, et al. Carfilzomib, lenalidomide, and low-dose dexamethasone in elderly patients with newly diagnosed multiple myeloma. Haematologica 2014;99:e162-164.
-
(2014)
Haematologica
, vol.99
, pp. e162-e164
-
-
Dytfeld, D.1
Jasielec, J.2
Griffith, K.A.3
-
18
-
-
84880119544
-
Phase II clinical and correlative study of carfilzomib, lenalidomide, and dexamethasone (CRd) in newly diagnosed Multiple Myeloma (MM) patients [abstract]
-
732
-
Korde N, Zingone A, Kwok M, et al. Phase II clinical and correlative study of carfilzomib, lenalidomide, and dexamethasone (CRd) in newly diagnosed Multiple Myeloma (MM) patients [abstract]. Blood 2012;120: Abstract 732.
-
(2012)
Blood
, vol.120
-
-
Korde, N.1
Zingone, A.2
Kwok, M.3
-
19
-
-
84904487411
-
Phase II clinical and correlative study of carfilzomib, lenalidomide, and dexamethasone followed by lenalidomide extended dosing (CRD-R) induces high rates of MRD negativity in newly diagnosed multiple myeloma (MM) patients [abstract]
-
538
-
Korde N, Zingone A, Kwok M, et al. Phase II clinical and correlative study of carfilzomib, lenalidomide, and dexamethasone followed by lenalidomide extended dosing (CRD-R) induces high rates of MRD negativity in newly diagnosed multiple myeloma (MM) patients [abstract]. Blood 2013;122: Abstract 538.
-
(2013)
Blood
, vol.122
-
-
Korde, N.1
Zingone, A.2
Kwok, M.3
-
20
-
-
84955420512
-
Carfilzomib and dexamethasone versus bortezomib and dexamethasone for patients with relapsed or refractory multiple myeloma (ENDEAVOR): A randomised, phase 3, open-label, multicentre study
-
Dimopoulos MA, Moreau P, Palumbo A, et al. Carfilzomib and dexamethasone versus bortezomib and dexamethasone for patients with relapsed or refractory multiple myeloma (ENDEAVOR): a randomised, phase 3, open-label, multicentre study. Lancet Oncol 2016;17:27-38.
-
(2016)
Lancet Oncol
, vol.17
, pp. 27-38
-
-
Dimopoulos, M.A.1
Moreau, P.2
Palumbo, A.3
-
21
-
-
84942436321
-
Targeting CD38 with daratumumab monotherapy in multiple myeloma
-
Lokhorst HM, Plesner T, Laubach J P, et al. Targeting CD38 with daratumumab monotherapy in multiple myeloma. N Engl J Med 2015;373:1207-1219.
-
(2015)
N Engl J Med
, vol.373
, pp. 1207-1219
-
-
Lokhorst, H.M.1
Plesner, T.2
Laubach, J.P.3
-
22
-
-
84946713813
-
Phase II study of daratumumab (DARA) monotherapy in patients with >3 lines of prior therapy or double refractory multiple myeloma (MM):54767414MMY2002 (Sirius) [abstract]
-
LBA8512
-
Lonial S, Weiss B, Usmani S, et al. Phase II study of daratumumab (DARA) monotherapy in patients with >3 lines of prior therapy or double refractory multiple myeloma (MM):54767414MMY2002 (Sirius) [abstract]. J Clin Oncol 2015;33(15 Suppl): Abstract LBA8512.
-
(2015)
J Clin Oncol
, vol.33
, Issue.15
-
-
Lonial, S.1
Weiss, B.2
Usmani, S.3
-
23
-
-
52049104695
-
CS1, a potential new therapeutic antibody target for the treatment of multiple myeloma
-
Hsi ED, Steinle R, Balasa B, et al. CS1, a potential new therapeutic antibody target for the treatment of multiple myeloma. Clin Cancer Res 2008;14:2775-2784.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 2775-2784
-
-
Hsi, E.D.1
Steinle, R.2
Balasa, B.3
-
24
-
-
84940581656
-
ELOQUENT-2: A phase III, randomized, open-label study of lenalidomide (Len)/dexamethasone (dex) with/without elotuzumab (Elo) in patients (pts) with relapsed/refractory multiple myeloma (RRMM) [abstract]
-
8508
-
Lonial S, Dimopoulos MA, Palumbo A, et al. ELOQUENT-2: a phase III, randomized, open-label study of lenalidomide (Len)/dexamethasone (dex) with/without elotuzumab (Elo) in patients (pts) with relapsed/refractory multiple myeloma (RRMM) [abstract]. J Clin Oncol 2015;33(Suppl): Abstract 8508.
-
(2015)
J Clin Oncol
, vol.33
-
-
Lonial, S.1
Dimopoulos, M.A.2
Palumbo, A.3
-
25
-
-
84954253781
-
Ixazomib, an investigational oral proteasome inhibitor (PI), in combination with lenalidomide and dexamethasone (IRd), significantly extends progression-free survival (PFS) for patients (Pts) with relapsed and/or refractory multiple myeloma (RRMM): The phase 3 TOURMALINE-MM1 study
-
Moreau P, Masszi T, Grzasko N, et al. Ixazomib, an investigational oral proteasome inhibitor (PI), in combination with lenalidomide and dexamethasone (IRd), significantly extends progression-free survival (PFS) for patients (Pts) with relapsed and/or refractory multiple myeloma (RRMM): the phase 3 TOURMALINE-MM1 study. Blood 2015;126:727-727.
-
(2015)
Blood
, vol.126
, pp. 727
-
-
Moreau, P.1
Masszi, T.2
Grzasko, N.3
-
26
-
-
84905982938
-
Phase 1 study of weekly dosing with the investigational oral proteasome inhibitor ixazomib in relapsed/refractory multiple myeloma
-
Kumar SK, Bensinger WI, Zimmerman TM, et al. Phase 1 study of weekly dosing with the investigational oral proteasome inhibitor ixazomib in relapsed/refractory multiple myeloma. Blood 2014;124:1047-1055.
-
(2014)
Blood
, vol.124
, pp. 1047-1055
-
-
Kumar, S.K.1
Bensinger, W.I.2
Zimmerman, T.M.3
-
27
-
-
84905962613
-
Phase 1 study of twice-weekly ixazomib, an oral proteasome inhibitor, in relapsed/refractory multiple myeloma patients
-
Richardson PG, Baz R, Wang M, et al. Phase 1 study of twice-weekly ixazomib, an oral proteasome inhibitor, in relapsed/refractory multiple myeloma patients. Blood 2014;124:1038-1046.
-
(2014)
Blood
, vol.124
, pp. 1038-1046
-
-
Richardson, P.G.1
Baz, R.2
Wang, M.3
-
28
-
-
84939494205
-
Phase 2 trial of ixazomib in patients with relapsed multiple myeloma not refractory to bortezomib
-
Kumar SK, LaPlant B, Roy V, et al. Phase 2 trial of ixazomib in patients with relapsed multiple myeloma not refractory to bortezomib. Blood Cancer J 2015;5:e338.
-
(2015)
Blood Cancer J
, vol.5
, pp. e338
-
-
Kumar, S.K.1
La Plant, B.2
Roy, V.3
-
29
-
-
84964355331
-
Randomized phase 2 trial of two different doses of ixazomib in patients with relapsed multiple myeloma not refractory to bortezomib
-
Kumar SK, Laplant BR, Reeder CB, et al. Randomized phase 2 trial of two different doses of ixazomib in patients with relapsed multiple myeloma not refractory to bortezomib. Blood 2015;126:3050-3050.
-
(2015)
Blood
, vol.126
, pp. 3050
-
-
Kumar, S.K.1
Laplant, B.R.2
Reeder, C.B.3
-
30
-
-
84996539244
-
Safety and efficacy in the stratus (MM-010) trial, a single-arm phase 3b study evaluating pomalidomide + low-dose dexamethasone in patients with refractory or relapsed and refractory multiple myeloma
-
80 December 6-9, San Francisco, California
-
Dimopoulos MA, Palumbo A, Weisel K, et al. Safety and efficacy in the stratus (MM-010) trial, a single-arm phase 3b study evaluating pomalidomide + low-dose dexamethasone in patients with refractory or relapsed and refractory multiple myeloma. Presented at the American Society of Hematology Annual Meeting; December 6-9, 2014; San Francisco, California. Abstract 80.
-
(2014)
The American Society of Hematology Annual Meeting
-
-
Dimopoulos, M.A.1
Palumbo, A.2
Weisel, K.3
-
31
-
-
84884702483
-
Pomalidomide plus low-dose dexamethasone versus high-dose dexamethasone alone for patients with relapsed and refractory multiple myeloma (MM-003): A randomised, openlabel, phase 3 trial
-
San Miguel J, Weisel K, Moreau P, et al. Pomalidomide plus low-dose dexamethasone versus high-dose dexamethasone alone for patients with relapsed and refractory multiple myeloma (MM-003): a randomised, openlabel, phase 3 trial. Lancet Oncol 2013;14:1055-1066.
-
(2013)
Lancet Oncol
, vol.14
, pp. 1055-1066
-
-
San Miguel, J.1
Weisel, K.2
Moreau, P.3
-
32
-
-
67349228774
-
Development of the pan-DAC inhibitor panobinostat (LBH589): Successes and challenges
-
Atadja P. Development of the pan-DAC inhibitor panobinostat (LBH589): successes and challenges. Cancer Lett 2009;280:233-241.
-
(2009)
Cancer Lett
, vol.280
, pp. 233-241
-
-
Atadja, P.1
-
33
-
-
84908133944
-
Panobinostat plus bortezomib and dexamethasone versus placebo plus bortezomib and dexamethasone in patients with relapsed or relapsed and refractory multiple myeloma: A multicentre, randomised, double-blind phase 3 trial
-
San-Miguel J F, Hungria VT, Yoon SS, et al. Panobinostat plus bortezomib and dexamethasone versus placebo plus bortezomib and dexamethasone in patients with relapsed or relapsed and refractory multiple myeloma: a multicentre, randomised, double-blind phase 3 trial. Lancet Oncol 2014;15:1195-1206.
-
(2014)
Lancet Oncol
, vol.15
, pp. 1195-1206
-
-
San-Miguel, J.F.1
Hungria, V.T.2
Yoon, S.S.3
-
34
-
-
84884699420
-
PANORAMA 2: Panobinostat in combination with bortezomib and dexamethasone in patients with relapsed and bortezomib-refractory myeloma
-
Richardson PG, Schlossman RL, Alsina M, et al. PANORAMA 2: panobinostat in combination with bortezomib and dexamethasone in patients with relapsed and bortezomib-refractory myeloma. Blood 2013;122:2331-2337.
-
(2013)
Blood
, vol.122
, pp. 2331-2337
-
-
Richardson, P.G.1
Schlossman, R.L.2
Alsina, M.3
-
35
-
-
84959357825
-
Panobinostat plus bortezomib and dexamethasone in previously treated multiple myeloma: Outcomes by prior treatment
-
Richardson PG, Hungria VT, Yoon SS, et al. Panobinostat plus bortezomib and dexamethasone in previously treated multiple myeloma: outcomes by prior treatment. Blood 2016;127:713-721.
-
(2016)
Blood
, vol.127
, pp. 713-721
-
-
Richardson, P.G.1
Hungria, V.T.2
Yoon, S.S.3
-
36
-
-
84929152720
-
Phase I/II study of the combination of panobinostat and carfilzomib in patients with relapsed/refractory multiple myeloma
-
Berdeja JG, Hart LL, Mace JR, et al. Phase I/II study of the combination of panobinostat and carfilzomib in patients with relapsed/refractory multiple myeloma. Haematologica 2015;100:670-676.
-
(2015)
Haematologica
, vol.100
, pp. 670-676
-
-
Berdeja, J.G.1
Hart, L.L.2
Mace, J.R.3
-
37
-
-
84947269176
-
A phase I/II study of the combination of panobinostat (PAN) and carfilzomib (CFZ) in patients (pts) with relapsed or relapsed/refractory multiple myeloma (MM) [Abstract]
-
8513
-
Berdeja JG, Gregory TK, Matous J, et al. A phase I/II study of the combination of panobinostat (PAN) and carfilzomib (CFZ) in patients (pts) with relapsed or relapsed/refractory multiple myeloma (MM) [Abstract]. J Clin Oncol 2015;33(Suppl): Abstract 8513.
-
(2015)
J Clin Oncol
, vol.33
-
-
Berdeja, J.G.1
Gregory, T.K.2
Matous, J.3
|