Neurodegenerative disease: Complement mediates pathological pruning

Nature Reviews Neuroscience

Volumn 17, Issue 6, 2016, Pages 336-

  Whalley, Katherine ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; COMPLEMENT; COMPLEMENT COMPONENT C1Q; COMPLEMENT COMPONENT C3; COMPLEMENT COMPONENT C3 RECEPTOR;

ALZHEIMER DISEASE; AMYLOID PLAQUE; COMPLEMENT ACTIVATION; COMPLEMENT DEPOSITION; COMPLEMENT SYSTEM; HUMAN; INTERNALIZATION; MICROGLIA; MOLECULAR PATHOLOGY; NEUROPATHOLOGY; NONHUMAN; NOTE; PRIORITY JOURNAL; SYNAPSE; ANIMAL; MOUSE;

ALZHEIMER DISEASE; ANIMALS; COMPLEMENT SYSTEM PROTEINS; MICE; MICROGLIA; SYNAPSES;

EID: 84964374529     PISSN: 1471003X     EISSN: 14710048     Source Type: Journal    
DOI: 10.1038/nrn.2016.52     Document Type: Note

References (2)

1. Hong S, et al. Complement and microglia mediate early synapse loss in Alzheimer mouse models. Science http://dx.doi.org/.10.1126/science.aad8373 (2016).
2. Heppner F.L, et al. Immune attack: the role of inflammation in Alzheimer disease. Nat. Rev. Neurosci. 16, 358-372 (2015)